430 research outputs found
Prompt Beta Spectroscopy as a Diagnostic for Mix in Ignited NIF Capsules
The National Ignition Facility (NIF) technology is designed to drive
deuterium-tritium (DT) internal confinement fusion (ICF) targets to ignition
using indirect radiation from laser beam energy captured in a hohlraum.
Hydrodynamical instabilities at interfaces in the ICF capsule leading to mix
between the DT fue l and the ablator shell material are of fundamental physical
interest and can affect the performance characteristics of the capsule. In this
Letter we describe new radiochemical diagnostics for mix processes in ICF
capsules with plastic or Be (0.9%Cu) ablator shells. Reactions of high-energy
tritons with shell material produce high-energy -emitters.
We show that mix between the DT fuel and the shell material enhances
high-energy prompt beta emission from these reactions by more than an order of
magnitude over that expected in the absence of mix
Coherent X-ray Diffractive Imaging; applications and limitations
The inversion of a diffraction pattern offers aberration-free
diffraction-limited 3D images without the resolution and depth-of-field
limitations of lens-based tomographic systems, the only limitation being
radiation damage. We review our experimental results, discuss the fundamental
limits of this technique and future plans.Comment: 7 pages, 8 figure
Darwin-Lagrangian Analysis for the Interaction of a Point Charge and a Magnet: Considerations Related to the Controversy Regarding the Aharonov-Bohm and Aharonov-Casher Phase Shifts
The classical electromagnetic interaction of a point charge and a magnet is
discussed by first calculating the interaction of point charge with a simple
model magnetic moment and then suggesting a multiparticle limit. The Darwin
Lagrangian is used to analyze the electromagnetic behavior of the model
magnetic moment (composed of two oppositely charged particles of different mass
in an initially circular orbit) interacting with a passing point charge. The
changing mangetic moment is found to put a force back on a passing charge; this
force is of order 1/c^2 and depends upon the magnitude of the magnetic moment.
It is suggested that in the limit of a multiparticle magnetic toroid, the
electric fields of the passing charge are screened out of the body of the
magnet while the magnetic fields penetrate into the magnet. This is consistent
with our understanding of the penetration of electromagnetic velocity fields
into ohmic conductors. Conservation laws are discussed. The work corresponds to
a classical electromagnetic analysis of the interaction which is basic to
understanding the controversy over the Aharonov-Bohm and Aharonov-Casher phase
shifts and represents a refutation of the suggestions of Aharonov, Pearle, and
Vaidman.Comment: 33 page
Professional development in teaching and learning for early career academic geographers: Contexts, practices and tensions
This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Geography in Higher Education on 16th May 2011, available online: doi: 10.1080/03098265.2011.563380This paper provides a review of the practices and tensions informing approaches to professional development for early career academic geographers who are teaching in higher education. We offer examples from Britain, Canada, Nigeria and the USA. The tensions include: institutional and departmental cultures; models that offer generic and discipline-specific approaches; the credibility of alternative settings for professional development in teaching and learning; the valuing of professional development and of teaching in academic systems of reward and recognition; and the challenges of balancing professional and personal life. We summarize concepts of good practice and suggest opportunities for future research
Geometric Phases and Mielnik's Evolution Loops
The cyclic evolutions and associated geometric phases induced by
time-independent Hamiltonians are studied for the case when the evolution
operator becomes the identity (those processes are called {\it evolution
loops}). We make a detailed treatment of systems having equally-spaced energy
levels. Special emphasis is made on the potentials which have the same spectrum
as the harmonic oscillator potential (the generalized oscillator potentials)
and on their recently found coherent states.Comment: 11 pages, harvmac, 2 figures available upon request; CINVESTAV-FIS
GFMR 11/9
Influence of real-world characteristics on outcomes for patients with methicillin-resistant Staphylococcal skin and soft tissue infections:a multi-country medical chart review in Europe
BACKGROUND: Patient-related (demographic/disease) and treatment-related (drug/clinician/hospital) characteristics were evaluated as potential predictors of healthcare resource use and opportunities for early switch (ES) from intravenous (IV)-to-oral methicillin-resistant Staphylococcus aureus (MRSA)-active antibiotic therapy and early hospital discharge (ED). METHODS: This retrospective observational medical chart study analyzed patients (across 12 European countries) with microbiologically confirmed MRSA complicated skin and soft tissue infections (cSSTI), ≥3 days of IV anti-MRSA antibiotics during hospitalization (July 1, 2010-June 30, 2011), and discharged alive by July 31, 2011. Logistic/linear regression models evaluated characteristics potentially associated with actual resource use (length of IV therapy, length of hospital stay [LOS], IV-to-oral antibiotic switch), and ES and ED (using literature-based and expert-verified criteria) outcomes. RESULTS: 1542 patients (mean ± SD age 60.8 ± 16.5 years; 61.5% males) were assessed with 81.0% hospitalized for MRSA cSSTI as the primary reason. Several patient demographic, infection, complication, treatment, and hospital characteristics were predictive of length of IV therapy, LOS, IV-to-oral antibiotic switch, or ES and ED opportunities. Outcomes and ES and ED opportunities varied across countries. Length of IV therapy and LOS (r = 0.66, p < 0.0001) and eligibilities for ES and ED (r = 0.44, p < 0.0001) showed relatively strong correlations. IV-to-oral antibiotic switch patients had significantly shorter length of IV therapy (−5.19 days, p < 0.001) and non-significantly shorter LOS (−1.86 days, p > 0.05). Certain patient and treatment characteristics were associated with increased odds of ES (healthcare-associated/ hospital-acquired infection) and ED (patient living arrangements, healthcare-associated/ hospital-acquired infection, initiating MRSA-active treatment 1–2 days post cSSTI index date, existing ED protocol), while other factors decreased the odds of ES (no documented MRSA culture, ≥4 days from admission to cSSTI index date, IV-to-oral switch, IV line infection) and ED (dementia, no documented MRSA culture, initiating MRSA-active treatment ≥3 days post cSSTI index date, existing ES protocol). CONCLUSIONS: Practice patterns and opportunity for further ES and ED were affected by several infection, treatment, hospital, and geographical characteristics, which should be considered in identifying ES and ED opportunities and designing interventions for MRSA cSSTI to reduce IV days and LOS while maintaining the quality of care. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2334-14-476) contains supplementary material, which is available to authorized users
Laser-induced nonresonant nuclear excitation in muonic atoms
Coherent nuclear excitation in strongly laser-driven muonic atoms is
calculated. The nuclear transition is caused by the time-dependent Coulomb
field of the oscillating charge density of the bound muon. A closed-form
analytical expression for electric multipole transitions is derived and applied
to various isotopes; the excitation probabilities are in general very small. We
compare the process with other nuclear excitation mechanisms through coupling
with atomic shells and discuss the prospects to observe it in experiment.Comment: 7 pages, 5 figure
Study protocol: evaluation of a parenting and stress management programme: a randomised controlled trial of Triple P discussion groups and stress control
<br>Background: Children displaying psychosocial problems are at an increased risk of negative developmental outcomes. Parenting practices are closely linked with child development and behaviour, and parenting programmes have been recommended in the treatment of child psychosocial problems. However, parental mental health also needs to be addressed when delivering parenting programmes as it is linked with parenting practices, child outcomes, and treatment outcomes of parenting programmes. This paper describes the protocol of a study examining the effects of a combined intervention of a parenting programme and a cognitive behavioural intervention for mental health problems.</br>
<br>Methods: The effects of a combined intervention of Triple P Discussion Groups and Stress Control will be examined using a randomised controlled trial design. Parents with a child aged 3?8?years will be recruited to take part in the study. After obtaining informed consent and pre-intervention measures, participants will be randomly assigned to either an intervention or a waitlist condition. The two primary outcomes for this study are change in dysfunctional/ineffective parenting practices and change in symptoms of depression, anxiety, and stress. Secondary outcomes are child behaviour problems, parenting experiences, parental self-efficacy, family relationships, and positive parental mental health. Demographic information, participant satisfaction with the intervention, and treatment fidelity data will also be collected. Data will be collected at pre-intervention, mid-intervention, post-intervention, and 3-month follow-up.</br>
<br>Discussion: The aim of this paper is to describe the study protocol of a randomised controlled trial evaluating the effects of a combined intervention of Triple P Discussion Groups and Stress Control in comparison to a waitlist condition. This study is important because it will provide evidence about the effects of this combined intervention for parents with 3?8?year old children. The results of the study could be used to inform policy about parenting support and support for parents with mental health problems. Trial registration ClinicalTrial.gov: NCT01777724, UTN: U1111-1137-1053.</br>
Inflammatory bowel disease, such as Ulcerative colitis, is a risk factor for recurrent thromboembolic events: a case report
Ulcerative colitis (UC), a member of the family of inflammatory bowel disease (IBD), occurs worldwide. It has an incidence which in recent years has been rising in areas such as Southern Europe and Asia, while remaining relatively constant in Northern Europe and North America
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