The dynamics of certain indicators of nuclein metabolism during hypokinesia in rats of different ages under the influence of sinusoidal modulated currents and measured physical load

The influence of sinusoidal modulated currents was studied and physical loads on the nucleic acid content and the nucleotide composition of the total RNA in muscles of rats of various ages under conditions of hypodynamia were measured. Methodology utilized is described and conclusions are presented

The influence of modulated sinusoidal current on the state of chromatin from neurons of the cerebral cortex of rats in hypokinesia

The biochemical changes under the influence of modulated sinusoidal current in the central nervous system were investigated. The methodology used is discussed, the results are reported in a table, and conclusions are presented

In Vitro Cytotoxicity of CdSe/ZnS Quantum Dots and Their Interaction with Biological Systems

Semiconductor nanocrystals (quantum dots, QDs) have a wide range of potential application in multiplexed tissue and cell imaging, and for in vivo molecular diagnostics and therapy. Therefore studying of the toxicity of QDs and their influence on various cellular processes in vitro is necessary to understand their interaction with living systems.; The paper presents the results of studies on the evaluation of CdSe/ZnS QD cytotoxicity, as well as the results of studying their interaction with freshly prepared human monocytes in vitro. Keywords: Quantum dots, semiconductor nanocrystals, cytotoxicity, in vitro models, monocytes

Konus-Wind and Helicon-Coronas-F Observations of Solar Flares

Results of solar flare observations obtained in the Konus-Wind experiment from November, 1994 to December, 2013 and in the Helicon Coronas-F experiment during its operation from 2001 to 2005, are presented. For the periods indicated Konus-Wind detected in the trigger mode 834 solar flares, and Helicon-Coronas-F detected more than 300 solar flares. A description of the instruments and data processing techniques are given. As an example, the analysis of the spectral evolution of the flares SOL2012-11-08T02:19 (M 1.7) and SOL2002-03-10T01:34 (C5.1) is made with the Konus-Wind data and the flare SOL2003-10-26T06:11 (X1.2) is analyzed in the 2.223 MeV deuterium line with the Helicon-Coronas-F data.Comment: Published version. A list of the Konus-Wind solar flare triggers and figures of their time profiles are available at http://www.ioffe.ru/LEA/Solar

A flaring X-ray pulsar in Dorado

A study of unusual gamma-ray bursts detected on March 5 and March 6, 1979 in the KONUS experiment on the Venera 11 and Venera 12 spacecraft shows their source to be flaring X-ray pulsar in Dorado

Preliminary results of a gamma-ray burst study in the Konus experiment on the Venera-11 and Venera-12 space probes

Twenty-one gamma-ray bursts and 68 solar flares in the hard X-ray range were detected on Venera-11 and Venera-12 space probes during the initial 50-day observation period. Major characteristics of the equipment used and preliminary data on the temporal structure and energy spectra of the gamma-ray bursts are considered. The pattern of gamma-ray burst frequency distribution vs. intensity, N(S), is established

Endonuclease from Proteus mirabilis

Two isoforms of nuclease displaying DNase and RNase activities were found in the culture liquid and periplasm of Proteus mirabilis. The enzyme was isolated from the periplasm and then purified to a functionally homogeneous state. The nuclease was equally potent in cleaving denatured and native DNAs by the endonuclease mechanism and was designated Pm endonuclease. The endonuclease was shown to be a temperature-dependent enzyme with a pH optimum of 10.4-10.6, requiring the presence of bivalent metal ions and inhibited by citrate and ethylenediaminetetraacetate. © 2001 MAIK "Nauka/Interperiodica"

Cytotoxicity of Polyelectrolyte Microcapsules Encoded with Semiconductor Nanocrystals

Polyelectrolyte microcapsules are promising carriers of drugs and diagnostic agents for designing targeted and controlled delivery systems design. The use of quantum dots (QDs) as fluorescent labels in bioimaging is a promising approach to bioimaging tool development. The potential toxicity of QDs makes their applicability as fluorescent labels in vivo questionable. Therefore, the cytotoxicity of polyelectrolyte microcapsules encoded with semiconductor nanocrystals has been investigated. Keywords: Polyelectrolyte microcapsules, semiconductor nanocrystals, cytotoxicity, theranostic agents

Phytoinsecticides to Fight Against Colorado Beetle

Nowadays researchers are focused on biological farming. In modern environmental conditions the reduction of the chemical load on the environment is a current issue. In the article the following plants are used as pest management, especially, with Colorado potato beetle: jimson weed, white hellebore, Camelina. They contain a lot of alkaloids and essential oils that inhibit weeds and frightening off potato pests. The use of such agricultural practices on large areas reduces the cost of chemical means of pest control and improves product quality while maintaining the environment

KW-Sun: The Konus-Wind Solar Flare Database in Hard X-ray and Soft Gamma-ray Ranges

We present a database of solar flares registered by the Konus-Wind instrument during more than 27 years of operation, from 1994 November to now (2022 June). The constantly updated database (hereafter KW-Sun) contains over 1000 events detected in the instrument's triggered mode and is accessible online at http://www.ioffe.ru/LEA/kwsun/. For each flare, the database provides time-resolved energy spectra in energy range from ~20 keV to ~15 MeV in FITS format along with count rate light curves in three wide energy bands G1 (~20-80 keV), G2 (~80-300 keV), and G3 (~300-1200 keV) with high time resolution (down to 16 ms) in ASCII and IDL SAV formats. This article focuses on the instrument capabilities in the context of solar observations, the structure of the KW-Sun data and their intended usage. The presented homogeneous data set obtained in the broad energy range with high temporal resolution during more than two full solar cycles is beneficial for both statistical and case studies as well as a source of context data for solar flare research.Comment: 10 pages, 6 figures, 1 table. Accepted for publication in ApJ