488 research outputs found
NLO QCD corrections to the production of Higgs plus two jets at the LHC
We present the calculation of the NLO QCD corrections to the associated
production of a Higgs boson and two jets, in the infinite top-mass limit. We
discuss the technical details of the computation and we show the numerical
impact of the radiative corrections on several observables at the LHC. The
results are obtained by using a fully automated framework for fixed order NLO
QCD calculations based on the interplay of the packages GoSam and Sherpa. The
evaluation of the virtual corrections constitutes an application of the
d-dimensional integrand-level reduction to theories with higher dimensional
operators. We also present first results for the one-loop matrix elements of
the partonic processes with a quark-pair in the final state, which enter the
hadronic production of a Higgs boson together with three jets in the infinite
top-mass approximation.Comment: 9 pages, 7 figures, references added, published in Phys.Lett.
Automated one-loop calculations with GoSam 2.0
We present the version 2.0 of the program GoSam, which is a public program
package to compute one-loop corrections to multi-particle processes. The
extended version of the "Binoth-Les-Houches-Accord" interface to Monte Carlo
programs is also implemented. This allows a large flexibility regarding the
combination of the code with various Monte Carlo programs to produce fully
differential NLO results, including the possibility of parton showering and
hadronisation. We describe the new features of the code and illustrate the wide
range of applicability for multi-particle processes at NLO, both within and
beyond the Standard Model.Comment: 9 pages, talk given at the conference "Loops and Legs in Quantum
Field Theory", Weimar, Germany, April 201
GoSam-2.0: a tool for automated one-loop calculations within the Standard Model and beyond
We present the version 2.0 of the program package GoSam for the automated
calculation of one-loop amplitudes. GoSam is devised to compute one-loop QCD
and/or electroweak corrections to multi-particle processes within and beyond
the Standard Model. The new code contains improvements in the generation and in
the reduction of the amplitudes, performs better in computing time and
numerical accuracy, and has an extended range of applicability. The extended
version of the "Binoth-Les-Houches-Accord" interface to Monte Carlo programs is
also implemented. We give a detailed description of installation and usage of
the code, and illustrate the new features in dedicated examples.Comment: replaced by published version and reference adde
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Assessing the consistency of satellite-derived upper tropospheric humidity measurements
Four upper tropospheric humidity (UTH) datasets derived from satellite sounders are evaluated to assess their consistency as part of the activities for the Global Energy and Water Exchanges (GEWEX) water vapor assessment project. The datasets include UTH computed from brightness temperature measurements of the 183.31±1 GHz channel of the Special Sensor Microwave – Humidity (SSM/T-2), Advanced Microwave Sounding Unit-B (AMSU-B), and Microwave Humidity Sounder (MHS) and from channel 12 of the High-resolution Infrared Radiation Sounder (HIRS). The four datasets are generally consistent in the interannual temporal and spatial variability of the tropics. Large positive anomalies peaked over the central equatorial Pacific region during El Niño events in the same phase with the increase of sea surface temperature (SST). Conversely, large negative anomalies were obtained during El Niño events when the tropical-domain average is taken. The weakened ascending branch of the Pacific Walker circulation in the western Pacific and the enhanced descending branches of the local Hadley circulation along the Pacific subtropics largely contributed to widespread drying areas and thus negative anomalies in the upper troposphere during El Niño events as shown in all four datasets. During a major El Niño event, UTH had higher correlations with the coincident precipitation (0.60 to 0.75) and with 200 hPa velocity potential (−0.42 to −0.64) than with SST (0.37 to 0.49). Due to differences in retrieval definitions and gridding procedures, there can be a difference of 3 %–5 % UTH between datasets on average, and larger magnitudes of anomaly values are usually observed in spatial maps of microwave UTH data. Nevertheless, the tropical-domain averaged anomalies of the datasets are close to each other with their differences being mostly less than 0.5 %, and more importantly the phases of the time series are generally consistent for variability studie
Statin associated necrotizing autoimmune myopathies in the Indigenous population: a case series from North Queensland
Aim: To describe clinical and histopathological features of statin associated necrotizing autoimmune myopathies (NAM) in Indigenous Australians and increase awareness of this condition amongst treating physicians.
Methods: Cases were collected through the Rheumatology Department at The Townsville Hospital between March 2012 and January 2015. A chart review was performed to obtain retrospective information about each case. We detail patient demographics, presenting features, histopathological findings, autoimmune profile, treatment and outcomes.
Results: 4 Indigenous Australians were identified as having a biopsy confirmed statin associated NAM. All patients had been on atorvastatin for at least 2 years and had significant proximal weakness with average CK level on presentation 16,820 U/L. Predisposing factors for myopathy included vitamin D deficiency and diabetes mellitus (all cases), with primary hypothyroidism and liver cirrhosis identified in two other cases. Two individuals were positive for the auto-antibody anti-HMGCR. Histopathological findings included muscle necrosis with varying degrees of inflammation, membrane attack complex (MAC) deposition and MHC-1 upregulation. Treatment involved various combinations of prednisolone, IVIG, methotrexate and mycophenolate. Recovery was slow but favourable in all cases with an average length of inpatient stay of 54 days. There was a significant delay in diagnosis of 1–3 months in two of the cases.
Conclusions: The statin associated necrotizing autoimmune myopathies are rare but important disorders that cause significant morbidity to affected individuals. Given the prevalence of cardiovascular disease in Indigenous Australians, further research is required to facilitate earlier diagnosis and improved treatment outcomes
Statin associated necrotizing autoimmune myopathies in the Indigenous population: a case series from North Queensland
Aim: To describe clinical and histopathological features of statin associated necrotizing autoimmune myopathies (NAM) in Indigenous Australians and increase awareness of this condition amongst treating physicians.
Methods: Cases were collected through the Rheumatology Department at The Townsville Hospital between March 2012 and January 2015. A chart review was performed to obtain retrospective information about each case. We detail patient demographics, presenting features, histopathological findings, autoimmune profile, treatment and outcomes.
Results: 4 Indigenous Australians were identified as having a biopsy confirmed statin associated NAM. All patients had been on atorvastatin for at least 2 years and had significant proximal weakness with average CK level on presentation 16,820 U/L. Predisposing factors for myopathy included vitamin D deficiency and diabetes mellitus (all cases), with primary hypothyroidism and liver cirrhosis identified in two other cases. Two individuals were positive for the auto-antibody anti-HMGCR. Histopathological findings included muscle necrosis with varying degrees of inflammation, membrane attack complex (MAC) deposition and MHC-1 upregulation. Treatment involved various combinations of prednisolone, IVIG, methotrexate and mycophenolate. Recovery was slow but favourable in all cases with an average length of inpatient stay of 54 days. There was a significant delay in diagnosis of 1–3 months in two of the cases.
Conclusions: The statin associated necrotizing autoimmune myopathies are rare but important disorders that cause significant morbidity to affected individuals. Given the prevalence of cardiovascular disease in Indigenous Australians, further research is required to facilitate earlier diagnosis and improved treatment outcomes
Clear sky fraction above Indonesia: an analysis for astronomical site selection
We report a study of cloud cover over Indonesia based on meteorological
satellite data, spanning over the past 15 years (from 1996 to 2010) in order to
be able to select a new astronomical site capable to host a multi-wavelength
astronomical observatory. High spatial resolution of meteorological satellite
data acquired from {\it Geostationary Meteorological Satellite 5} ({\it GMS
5}), {\it Geostationary Operational Environmental Satellite 9} ({\it GOES 9}),
and {\it Multi-functional Transport Satellite-1R} ({\it MTSAT-1R}) are used to
derive yearly average clear fractions over the regions of Indonesia. This
parameter is determined from temperature measurement of the IR3 channel (water
vapor, 6.7 m) for high altitude clouds (cirrus) and from the IR1 channel
(10.7 m) for lower altitude clouds. Accordingly, an algorithm is developed
to detect the corresponding clouds. The results of this study are then adopted
to select the best possible sites in Indonesia to be analysed further by
performing in situ measurements planned for the coming years. The results
suggest that regions of East Nusa Tenggara, located in south-eastern part of
Indonesia, are the most promising candidates for such an astronomical site.
Yearly clear sky fraction of this regions may reach better than 70 per cent
with an uncertainty of 10 per cent.Comment: 15 pages, 13 figures, and 4 table
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Radiative forcing of climate: the historical evolution of the radiative forcing concept, the forcing agents and their quantification, and applications
We describe the historical evolution of the conceptualization, formulation, quantification, application and utilization of “radiative forcing (RF, see e.g., IPCC, 1990)” of Earth’s climate.
Basic theories of shortwave and long wave radiation were developed through the 19th and 20th centuries, and established the analytical framework for defining and quantifying the perturbations to the Earth’s radiative energy balance by natural and anthropogenic influences. The insight that the Earth’s climate could be radiatively forced by changes in carbon dioxide, first introduced in the 19th century, gained empirical support with sustained observations of the atmospheric concentrations of the gas beginning in 1957. Advances in laboratory and field measurements, theory, instrumentation, computational technology, data and analysis of well-mixed greenhouse gases and the global climate system through the 20th Century enabled the development and formalism of RF; this allowed RF to be related to changes in global-mean surface temperature with the aid of increasingly sophisticated models. This in turn led to RF becoming firmly established as a principal concept in climate science by 1990.
The linkage with surface temperature has proven to be the most important application of the RF concept, enabling a simple metric to evaluate the relative climate impacts of different agents. The late 1970s and 1980s saw accelerated developments in quantification including the first assessment of the effect of the forcing due to doubling of carbon dioxide on climate (the “Charney” report, National Research Council, 1979). The concept was subsequently extended to a wide variety of agents beyond well-mixed greenhouse gases (WMGHGs: carbon dioxide, methane, nitrous oxide, and halocarbons) to short-lived species such as ozone. The WMO (1986) and IPCC (1990) international assessments began the important sequence of periodic evaluations and quantifications of the forcings by natural (solar irradiance changes and stratospheric aerosols resulting from volcanic eruptions) and a growing set of anthropogenic agents (WMGHGs, ozone, aerosols, land surface changes, contrails). From 1990s to the present, knowledge and scientific confidence in the radiative agents acting on the climate system has proliferated. The conceptual basis of RF has also evolved as both our understanding of the way radiative forcing drives climate change, and the diversity of the forcing mechanisms, have grown. This has led to the current situation where “Effective Radiative Forcing (ERF, e.g., IPCC, 2013)” is regarded as the preferred practical definition of radiative forcing in order to better capture the link between forcing and global-mean surface temperature change. The use of ERF, however, comes with its own attendant issues, including challenges in its diagnosis from climate models, its applications to small forcings, and blurring of the distinction between rapid climate adjustments (fast responses) and climate feedbacks; this will necessitate further elaboration of its utility in the future. Global climate model simulations of radiative perturbations by various agents have established how the forcings affect other climate variables besides temperature e.g., precipitation. The forcing-response linkage as simulated by models, including the diversity in the spatial distribution of forcings by the different agents, has provided a practical demonstration of the effectiveness of agents in perturbing the radiative energy balance and causing climate changes.
The significant advances over the past half-century have established, with very high confidence, that the global-mean ERF due to human activity since preindustrial times is positive (the 2013 IPCC assessment gives a best estimate of 2.3 W m-2, with a range from 1.1 to 3.3 W m-2; 90% confidence interval). Further, except in the immediate aftermath of climatically-significant volcanic eruptions, the net anthropogenic forcing dominates over natural radiative forcing mechanisms. Nevertheless, the substantial remaining uncertainty in the net anthropogenic ERF leads to large uncertainties in estimates of climate sensitivity from observations and in predicting future climate impacts. The uncertainty in the ERF arises principally from the incorporation of the rapid climate adjustments in the formulation, the well-recognized difficulties in characterizing the preindustrial state of the atmosphere, and the incomplete knowledge of the interactions of aerosols with clouds. This uncertainty impairs the quantitative evaluation of climate adaptation and mitigation pathways in the future. A grand challenge in Earth System science lies in continuing to sustain the relatively simple essence of the radiative forcing concept in a form similar to that originally devised, and at the same time improving the quantification of the forcing. This, in turn, demands an accurate, yet increasingly complex and comprehensive, accounting of the relevant processes in the climate system
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