488 research outputs found

    NLO QCD corrections to the production of Higgs plus two jets at the LHC

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    We present the calculation of the NLO QCD corrections to the associated production of a Higgs boson and two jets, in the infinite top-mass limit. We discuss the technical details of the computation and we show the numerical impact of the radiative corrections on several observables at the LHC. The results are obtained by using a fully automated framework for fixed order NLO QCD calculations based on the interplay of the packages GoSam and Sherpa. The evaluation of the virtual corrections constitutes an application of the d-dimensional integrand-level reduction to theories with higher dimensional operators. We also present first results for the one-loop matrix elements of the partonic processes with a quark-pair in the final state, which enter the hadronic production of a Higgs boson together with three jets in the infinite top-mass approximation.Comment: 9 pages, 7 figures, references added, published in Phys.Lett.

    Automated one-loop calculations with GoSam 2.0

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    We present the version 2.0 of the program GoSam, which is a public program package to compute one-loop corrections to multi-particle processes. The extended version of the "Binoth-Les-Houches-Accord" interface to Monte Carlo programs is also implemented. This allows a large flexibility regarding the combination of the code with various Monte Carlo programs to produce fully differential NLO results, including the possibility of parton showering and hadronisation. We describe the new features of the code and illustrate the wide range of applicability for multi-particle processes at NLO, both within and beyond the Standard Model.Comment: 9 pages, talk given at the conference "Loops and Legs in Quantum Field Theory", Weimar, Germany, April 201

    GoSam-2.0: a tool for automated one-loop calculations within the Standard Model and beyond

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    We present the version 2.0 of the program package GoSam for the automated calculation of one-loop amplitudes. GoSam is devised to compute one-loop QCD and/or electroweak corrections to multi-particle processes within and beyond the Standard Model. The new code contains improvements in the generation and in the reduction of the amplitudes, performs better in computing time and numerical accuracy, and has an extended range of applicability. The extended version of the "Binoth-Les-Houches-Accord" interface to Monte Carlo programs is also implemented. We give a detailed description of installation and usage of the code, and illustrate the new features in dedicated examples.Comment: replaced by published version and reference adde

    Statin associated necrotizing autoimmune myopathies in the Indigenous population: a case series from North Queensland

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    Aim: To describe clinical and histopathological features of statin associated necrotizing autoimmune myopathies (NAM) in Indigenous Australians and increase awareness of this condition amongst treating physicians. Methods: Cases were collected through the Rheumatology Department at The Townsville Hospital between March 2012 and January 2015. A chart review was performed to obtain retrospective information about each case. We detail patient demographics, presenting features, histopathological findings, autoimmune profile, treatment and outcomes. Results: 4 Indigenous Australians were identified as having a biopsy confirmed statin associated NAM. All patients had been on atorvastatin for at least 2 years and had significant proximal weakness with average CK level on presentation 16,820 U/L. Predisposing factors for myopathy included vitamin D deficiency and diabetes mellitus (all cases), with primary hypothyroidism and liver cirrhosis identified in two other cases. Two individuals were positive for the auto-antibody anti-HMGCR. Histopathological findings included muscle necrosis with varying degrees of inflammation, membrane attack complex (MAC) deposition and MHC-1 upregulation. Treatment involved various combinations of prednisolone, IVIG, methotrexate and mycophenolate. Recovery was slow but favourable in all cases with an average length of inpatient stay of 54 days. There was a significant delay in diagnosis of 1–3 months in two of the cases. Conclusions: The statin associated necrotizing autoimmune myopathies are rare but important disorders that cause significant morbidity to affected individuals. Given the prevalence of cardiovascular disease in Indigenous Australians, further research is required to facilitate earlier diagnosis and improved treatment outcomes

    Statin associated necrotizing autoimmune myopathies in the Indigenous population: a case series from North Queensland

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    Aim: To describe clinical and histopathological features of statin associated necrotizing autoimmune myopathies (NAM) in Indigenous Australians and increase awareness of this condition amongst treating physicians. Methods: Cases were collected through the Rheumatology Department at The Townsville Hospital between March 2012 and January 2015. A chart review was performed to obtain retrospective information about each case. We detail patient demographics, presenting features, histopathological findings, autoimmune profile, treatment and outcomes. Results: 4 Indigenous Australians were identified as having a biopsy confirmed statin associated NAM. All patients had been on atorvastatin for at least 2 years and had significant proximal weakness with average CK level on presentation 16,820 U/L. Predisposing factors for myopathy included vitamin D deficiency and diabetes mellitus (all cases), with primary hypothyroidism and liver cirrhosis identified in two other cases. Two individuals were positive for the auto-antibody anti-HMGCR. Histopathological findings included muscle necrosis with varying degrees of inflammation, membrane attack complex (MAC) deposition and MHC-1 upregulation. Treatment involved various combinations of prednisolone, IVIG, methotrexate and mycophenolate. Recovery was slow but favourable in all cases with an average length of inpatient stay of 54 days. There was a significant delay in diagnosis of 1–3 months in two of the cases. Conclusions: The statin associated necrotizing autoimmune myopathies are rare but important disorders that cause significant morbidity to affected individuals. Given the prevalence of cardiovascular disease in Indigenous Australians, further research is required to facilitate earlier diagnosis and improved treatment outcomes

    Clear sky fraction above Indonesia: an analysis for astronomical site selection

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    We report a study of cloud cover over Indonesia based on meteorological satellite data, spanning over the past 15 years (from 1996 to 2010) in order to be able to select a new astronomical site capable to host a multi-wavelength astronomical observatory. High spatial resolution of meteorological satellite data acquired from {\it Geostationary Meteorological Satellite 5} ({\it GMS 5}), {\it Geostationary Operational Environmental Satellite 9} ({\it GOES 9}), and {\it Multi-functional Transport Satellite-1R} ({\it MTSAT-1R}) are used to derive yearly average clear fractions over the regions of Indonesia. This parameter is determined from temperature measurement of the IR3 channel (water vapor, 6.7 μ\mum) for high altitude clouds (cirrus) and from the IR1 channel (10.7 μ\mum) for lower altitude clouds. Accordingly, an algorithm is developed to detect the corresponding clouds. The results of this study are then adopted to select the best possible sites in Indonesia to be analysed further by performing in situ measurements planned for the coming years. The results suggest that regions of East Nusa Tenggara, located in south-eastern part of Indonesia, are the most promising candidates for such an astronomical site. Yearly clear sky fraction of this regions may reach better than 70 per cent with an uncertainty of 10 per cent.Comment: 15 pages, 13 figures, and 4 table
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