Diagnóstico bioclimático para produção de melão no município de Patos – PB : Bioclimatic diagnosis for melon production in the city of Patos – PB

A condições ambientais que possibilitam o cultivo do meloeiro estão relacionadas, sobretudo, aos fatores climáticos, tais como temperatura, luminosidade, umidade relativa do ar e características do solo e, a junção dessas condições pode favorecer ao meloeiro aumentar a produtividade de frutos e qualidade comercial. A pesquisa teve como objetivo avaliar as condições climatológicas e verificar a viabilidade da produção de melão cantaloupe no município de Patos, região semiárida paraibana. Os dados meteorológicos utilizados foram obtidos no Instituto Nacional de Meteorologia (INMET), no período de 2000 a 2020, sendo os elementos meteorológicos avaliados às temperaturas máximas, medias e mínimas e umidade relativa do ar, confrontando-se os dados obtidos com os dados ideais para a produção do melão. instalações para seu cultivo.   Constatou-se que no município de Patos apresenta durante o ano temperaturas máximas acima das exigidos pelo melão em todas as fases produtivas, sendo que temperaturas acima de 35 °C, como ocorre nos meses de Outubro a Janeiro

Adesão aos Universitários aos Diversos Níveis de Atividade Física

Este estudo objetiva identificar os níveis de atividade física existentes na UCG e os fatores relacionados com a adesão dos universitários a essas atividades. O trabalho sugere a necessidade de um programa de promoção da atividade física para todos os estudantes, em especial para os de Zootecnia, com altos índices de sedentarismo, a fim de prevenir danos futuros à  saúde

Chromosomal Polymorphism in the <i>Sporothrix schenckii</i> Complex

<div><p>Sporotrichosis is a polymorphic disease caused by a complex of thermodimorphic fungi including <i>S. brasiliensis, S. schenckii sensu stricto</i> (<i>s. str.</i>), <i>S. globosa</i> and <i>S. luriei.</i> Humans and animals can acquire the disease through traumatic inoculation of propagules into the subcutaneous tissue. Despite the importance of sporotrichosis as a disease that can take epidemic proportions there are just a few studies dealing with genetic polymorphisms and genomic architecture of these pathogens. The main objective of this study was to investigate chromosomal polymorphisms and genomic organization among different isolates in the <i>S. schenckii</i> complex. We used pulsed field gel electrophoresis (PFGE) to separate chromosomal fragments of isolated DNA, followed by probe hybridization. Nine loci (β-tubulin, calmodulin, catalase, chitin synthase 1, Internal Transcribed Spacer, Pho85 cyclin-dependent kinase, protein kinase C Ss-2, G protein α subunit and topoisomerase II) were mapped onto chromosomal bands of Brazilian isolates of <i>S. schenckii s. str.</i> and <i>S. brasiliensis</i>. Our results revealed the presence of intra and interspecies polymorphisms in chromosome number and size. The gene hybridization analysis showed that closely related species in phylogenetic analysis had similar genetic organizations, mostly due to identification of synteny groups in chromosomal bands of similar sizes. Our results bring new insights into the genetic diversity and genome organization among pathogenic species in the <i>Sporothrix schenckii</i> complex.</p></div

Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi studyResearch in context

Summary: Background: Mucositis is a common and highly impactful side effect of conventional and emerging cancer therapy and thus the subject of intense investigation. Although common practice, mucositis assessment is heterogeneously adopted and poorly guided, impacting evidence synthesis and translation. The Multinational Association of Supportive Care in Cancer (MASCC) Mucositis Study Group (MSG) therefore aimed to establish expert recommendations for how existing mucositis assessment tools should be used, in clinical care and trials contexts, to improve the consistency of mucositis assessment. Methods: This study was conducted over two stages (January 2022–July 2023). The first phase involved a survey to MASCC-MSG members (January 2022–May 2022), capturing current practices, challenges and preferences. These then informed the second phase, in which a set of initial recommendations were prepared and refined using the Delphi method (February 2023–May 2023). Consensus was defined as agreement on a parameter by >80% of respondents. Findings: Seventy-two MASCC-MSG members completed the first phase of the study (37 females, 34 males, mainly oral care specialists). High variability was noted in the use of mucositis assessment tools, with a high reliance on clinician assessment compared to patient reported outcome measures (PROMs, 47% vs 3%, 37% used a combination). The World Health Organization (WHO) and Common Terminology Criteria for Adverse Events (CTCAE) scales were most commonly used to assess mucositis across multiple settings. Initial recommendations were reviewed by experienced MSG members and following two rounds of Delphi survey consensus was achieved in 91 of 100 recommendations. For example, in patients receiving chemotherapy, the recommended tool for clinician assessment in clinical practice is WHO for oral mucositis (89.5% consensus), and WHO or CTCAE for gastrointestinal mucositis (85.7% consensus). The recommended PROM in clinical trials is OMD/WQ for oral mucositis (93.3% consensus), and PRO-CTCAE for gastrointestinal mucositis (83.3% consensus). Interpretation: These new recommendations provide much needed guidance on mucositis assessment and may be applied in both clinical practice and research to streamline comparison and synthesis of global data sets, thus accelerating translation of new knowledge into clinical practice. Funding: No funding was received