42 research outputs found

    Adolescent Brain Cognitive Development (ABCD) Study Linked External Data (LED): Protocol and practices for geocoding and assignment of environmental data

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    Our brain is constantly shaped by our immediate environments, and while some effects are transient, some have long-term consequences. Therefore, it is critical to identify which environmental risks have evident and long-term impact on brain development. To expand our understanding of the environmental context of each child, the Adolescent Brain Cognitive Development (ABCD) Study® incorporates the use of geospatial location data to capture a range of individual, neighborhood, and state level data based on the child\u27s residential location in order to elucidate the physical environmental contexts in which today\u27s youth are growing up. We review the major considerations and types of geocoded information incorporated by the Linked External Data Environmental (LED) workgroup to expand on the built and natural environmental constructs in the existing and future ABCD Study data releases. Understanding the environmental context of each youth furthers the consortium\u27s mission to understand factors that may influence individual differences in brain development, providing the opportunity to inform public policy and health organization guidelines for child and adolescent health

    Tracts originating from each of the clusters in the left hemisphere <i>K</i> = 6.

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    <p>Label colors (on left) match the cluster colors in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124797#pone.0124797.g002" target="_blank">Fig 2</a> (K = 6), which is reproduced at the bottom right. The color scale on brain maps represents the proportion of tract overlap across the participants, with the maps thresholded at 50%. Axial slices are shown in the left column, with slice locations marked on the sagittal slice with a blue line. Sagittal slices are shown in the right column, with slice locations marked on the axial slice with a blue line. MNI coordinates for the <i>z</i>-axis (axial slices) and <i>x</i>-axis (sagittal slices) are shown above the top row.</p

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    Cluster metrics.

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    <p>A) Variation of information metric for each <i>K</i> value and each hemisphere. Error bars represent 95% confidence intervals. B) Hierarchy index for each <i>K</i> value and each hemisphere. C) Symmetry measurement between the left and right hemispheres for each <i>K</i> value. D) Average of the standard deviation in the center-of-gravity across clusters for each <i>K</i> value.</p
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