Effet protecteur du calcium alimentaire lors de la carcinogenèse colique chimio-induite chez le rat Wistar

The aim of the study was fa evaluate in Wistar rats the promoting effect of poiyunsaturated (n-6)or saturated (végétaline) fats (24%) in colon carcinogenesis and the influence of supplemental calcium(1.5%) in this process. NMU was intrarectally instillated to induce colon carcinogenesis. Three differentcalcium salts (carbonate, lactate, and gluconate) were tested. Colon cancer incidence was higher in rats fed saturated fats than in those consuming unsaturated ones.The calcium supplementalion exhibits a protective effect depending on the chemical form used.Calcium lactate provide better protection than carbonate or gluconate.From the parameters those were used to follow carcinogenesis, resulls indicate that calcium salt acts through several ways, luminal and systemic. It chelates fatty acids and bile acids in the lumen and modulates the microbial transformations of cholesterol and bile acids, thus reflecting a modification of the intestinal microflora. The calcium balance suggests that the proteclive effect of calcium lactate is also efficient in reducing the cellular proliferation.Laminin P1 is proposed as a possible tumoral marker. Its serum levels are associated with colon tumorigenesis.Ce travail analyse chez les rats wistar, le rôle promoteur des régimes hyper lipidiques polyinsaturés (n6) et satures (vegetaline) ainsi que l'influence de la supplémentassions calcique (1.5%) sous forme carbonate, lactate ou gluconate vis-à-vis de la carcinogenèse colique induite par la NMU. Les lipides saturés, en présence de la NMU, sont des promoteurs potentiels de la carcinogenèse colique. La protection vis-à-vis de la carcinogenèse colique dépend de la forme chimique du sel de calcium. Le lactate de calcium semble avoir plus d'effets relativement au carbonate et gluconate de calcium. Cet effet protecteur du calcium se manifeste sur plusieurs niveaux (luminal et systémique) et à différentes étapes de la carcinogenèse (prolifération, promotion et progression). Le calcium agit principalement par la chélation des acides biliaires et surtout des acides gras et à travers la modulation des transformations bactériennes du cholestérol et de ses dérivés. Les bilans calciques suggèrent que l'effet du lactate de calcium est également systémique à travers la diminution de la prolifération cellulaire. La laminine p1 est proposée comme un marqueur tumoral. Les taux sériques de cette protéine sont associés à la tumorigenese colique

Influence de Mango Mania sur les habitudes alimentaires et de pratique de l’activité physique des enfants : perception des parents

L’objectif de l’étude était de déterminer la perception des parents sur l’influence de Mango Mania, une initiative de promotion de la santé en milieux scolaires, sur les habitudes alimentaires et de pratique de l’activité physique de leurs enfants. Un questionnaire a été administré aux parents d’enfants ayant participé aux initiatives de Mango Mania dans la région de Miramichi, Nouveau-Brunswick. Les résultats ont montré que Mango Mania a une influence positive sur les habitudes alimentaires et de pratique de l’activité physique des enfants. Cette influence semble aussi avoir été transmise aux parents qui indiquent avoir renforcé ces comportements positifs. De plus, les parents ont observé certains bienfaits chez leurs enfants, tel qu’un niveau plus élevé d’énergie et une meilleure concentration. Cette étude servira de base aux groupes qui souhaitent mettre sur pied une initiative dans les écoles de leur communauté afin de réduire le risque d’obésité et de diabète chez les enfants.The objective of this study was to determine parents’ perception on whether Mango Mania, a school-based health initiative, has an influence on eating habits and physical activity levels of their children. A questionnaire was administered to parents of children who participated in the Mango Mania initiative at their school in Miramichi, New Brunswick. Results show that Mango Mania has a positive influence on physical activity practices of children as well as their eating habits. Mango Mania also heightened parents’ awareness of the benefits of healthy eating and physical activity. Parents indicated encouraging these positive behaviors in their children. Parents also observed several other positive changes in their children, such as higher energy level and better concentration. This study provides the basis for groups who aspire to establish a school-based initiative in their communities in order to reduce the risk of obesity in children

Anthropometric Characteristics of Hospitalised Elderly Women: A Case-Control Study

This study assessed the anthropometric status of 451 hospitalised female patients aged 70 or over, at their admission to hospital, in reference to 77 healthy women of the same age. The most frequent diseases were circulatory diseases (40.8%), mental disorders (29.9%), respiratory diseases (12.4%), endocrine and metabolic diseases (11.5%), osteomuscular diseases (8.4%), and traumatisms (6.9%). The differences were significantly high for mid-arm circumference (MAC), triceps skinfold thickness (TSF), weight, weight/height, and body mass index (BMI). The patients with cancers, blood diseases, mental disorders, respiratory disease, digestive diseases, or traumatisms had the lowest values. All the indicators correlated in a similarly negative way with age. The decreased TSF was more pronounced among subjects with respiratory diseases. Measurement of anthropometric indicators, TSF in particular, should be part of preventive measures aimed at reducing malnutrition and its consequences in a hospital setting

Association of School Health Relationship Difficulties with Lack of Regular Physical Activity in Younger Adolescents: A Population Based Study

International audienc

Associations between School-Behavior-Health Difficulties and Subsequent Injuries among Younger Adolescents: A Population-based Study

International audienc