124 research outputs found

    Interfaces for understanding: Improving access to consumer health information.

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    This research will examine how health care consumers use a prototype interface that supports understanding and defining information problems through visual exploration of the medical domain (relationships among medical concepts and functional relationships in the human body)

    Assessing users' subjective satisfaction with the Information System for Youth Services (ISYS)

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    In this investigation, the Questionnaire for User Interaction Satisfaction (QUIS 5.5), a tool for assessing users' subjective satisfaction with specific aspects of the human/computer interface was used to assess the strengths and weaknesses of the Info rmation System for Youth Services (ISYS). ISYS is used by over 600 employees of the Maryland State Department of Juvenile Services (DJS) as a tracking device for juvenile offenders. Ratings and comments were collected from 254 DJS employees who use ISYS. The overall mean rating across all questions was 5.1 on a one to nine scale. The ten highest and lowest rated questions were identified. The QUIS allowed us to isolate subgroups which were compared with mean ratings from four measures of specific interfac e factors. The comments obtained from users provided suggestions, complaints and endorsements of the system. Also cross-referenced as CAR-TR-76

    Dual Navigation of Computerized Self-Administered Questionnaires and Organizational Records

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    This research explored dual navigation between organizational records and a computerized self-administered questionnaire. Two alternative interface designs for on-line questionnaire presentation were investigated. The form-based version of the questionnaire was divided into sections by question topic and each section was displayed as a single web page. In the item-based version, each question item was displayed individually on the screen. The navigational data collected was used to examine how participants moved between the organizational records and the questionnaire items as they completed the computerized questionnaire. Along with the navigational data, responses from pre- and post- questionnaires were analyzed. There were no significant differences in terms of accuracy, completion time, and ratings given in the pre- and post- questionnaires. However, there were significantly different navigational patterns between the two groups. Respondents in the form-based group tended to answer questions in more of a non-linear sequence. Additionally, the item-based group had more organizational record to organizational record traversals while the form-based group had more questionnaire item to questionnaire item traversals. Keywords : Questionnaires, Surveys, User Interface, World Wide Web, CSAQ, Navigation, Break-Dancing (Also corss-referenced as HCIL-TR-2000-22) (Also cross-referenced as UMIACS-TR-2000-71

    Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease

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    Ross River fever is a mosquito-transmitted viral disease that is endemic to Australia and the surrounding Pacific Islands. Ross River virus (RRV) belongs to the arthritogenic group of alphaviruses, which largely cause disease characterized by debilitating polyarthritis, rash, and fever. There is no specific treatment or licensed vaccine available, and the mechanisms of protective humoral immunity in humans are poorly understood. Here, we describe naturally occurring human mAbs specific to RRV, isolated from subjects with a prior natural infection. These mAbs potently neutralize RRV infectivity in cell culture and block infection through multiple mechanisms, including prevention of viral attachment, entry, and fusion. Some of the most potently neutralizing mAbs inhibited binding of RRV to Mxra8, a recently discovered alpahvirus receptor. Epitope mapping studies identified the A and B domains of the RRV E2 protein as the major antigenic sites for the human neutralizing antibody response. In experiments in mice, these mAbs were protective against cinical disease and reduced viral burden in multiple tissues, suggesting a potential therapeutic use for humans

    PenQuest Volume 2, Number 1

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    Table of Contents for this Volume: Untitled by Janet Collins Untitled by Judy Gozdur Last Hour of Light by Susan Reed Untitled by Judy Godzur Untitled by Rick Wagner Untitled by Carol Groover Untitled by R. Wagner Only in the Portico by Linda Banicki Untitled by Helen Hagadorn Private Place, Pubic Place by David Reed Untitled by Tammy Hutchinson Untitled by Tammy Hutchinson Madison Knights by Susan Reed Untitled by Sissy Crabtree The Price by Sandra Coleman Untitled by Ann Harrington Invasion of Privacy by Mark Touchton Untitled by Bruce Warner Untitled by Tom Schifanella Untitled by Tammy Hutchinson Bloodwork by Laura Jo Last Untitled by David Whitsett Burial Instructions by Bill Slaughter Untitled by S. Trevett PenQuest Interview: Joe Haldeman by David Reed Her Name Came from the Sea by Richard L. Ewart Untitled by V. Williams In the Woodshed by R. E. Mallery Untitled by Modesta Matthews Untitled by David Olson Illumination by E. Allen Tilley Untitled by Joseph Avanzini Everywoman by Laura Jo Last Untitled by Beth Goeckel Believe Me by Donna Kaluzniak Untitled by Judy Gozdur Untitled by Judy Gozdur Unicorn by David Reed Untitled by Susan Reed untitled by Paul Cramer Unititled by Lucinda Halsema The Violin by Richard L. Ewart Untitled by Maria Barry Untitled by Roger Whitt Jr. Haiku by Lori Nasrallah Rhymer’s Revolt by R. E. Mallery Untitled by Valerie William

    Motivations for collaborating with industry: has public policy influenced new academics in Argentina?

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    Between 2005 and 2015 a series of science, technology and innovation policies were deployed in Argentina among which academic research collaborations with industry was particularly fostered. This paper studies the effect of those policies on newer researchers, defined as those with PhD or postdoctoral scholarships, looking at their motivations to collaborate and, to some extent, at their actual collaborations with Industry. Our hypothesis is that those policies had a positive effect on young academics’ perception of collaborations with industry, now conceived as a dimension of their job, and also on actual collaborations. To conduct our study, we used an original database constructed from an online survey answered by more than 600 newer researchers. Empirical results partly confirm our hypothesis: a direct policy encouraging collaborations by providing collaborative grants was not associated with actual collaborations, while orienting research towards strategic areas–defined by the Science and Technology Ministry- is
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