IRONIC HEADLINE IN THE ORENBURG PRESS

В статье анализируются иронические заголовки 56 номеров газет «Южный Урал» (87 материалов), «Орская хроника» (82 материала) и «Оренбургская неделя» (34 материала). В список вошли не только материалы, содержащие преимущественно ироничный текст, но и тексты, содержащие ироничный заголовок. Большое количество примеров использования иронии в заголовках свидетельствует об эффективности данного риторического приема в письменной газетной речи.The article analyzes the ironic headlines of 56 issues of the newspapers “South Ural” (87 materials), “Orskaya Chronicle” (82 materials) and “Orenburg Week” (34 materials). The list includes not only materials containing predominantly ironic text, but also texts containing an ironic title. A large number of examples of the use of irony in headlines indicates the effectiveness of this rhetorical device in written newspaper speech

Newspaper Periodicals of the Orenburg Region on the Eve of a Political Transfer

В статье исследуется состояние газетной периодики Оренбуржья за последние тридцать лет. Показано взаимодействие органов власти и прессы в условиях рынка, противоречивость региональной государственной информационной политики, что обусловлено желанием органов власти и органов местного самоуправления всеми силами удержать электоральный ресурс СМИ. Делаются выводы о жесткой борьбе за концентрацию идеологических PR-ресурсов и сохранение рычагов влияния на руководство органов местного самоуправления.The article examines the state of the newspaper periodicals of the Orenburg region over the past thirty years. The interaction of authorities and the press in the market conditions, the inconsistency of the regional state information policy, which is caused by the desire of the authorities and local governments to retain the electoral resource of the media with all their might, is shown. Conclusions are drawn about a tough struggle for the concentration of ideological PR resources and the preservation of leverage over the leadership of local governments

Enabling magnetic resonance imaging of hollow-core microstructured optical fibers via nanocomposite coating

Optical fibers are widely used in bioimaging systems as flexible endoscopes capable of low-invasive penetration inside hollow tissue cavities. Here, we report on the technique which allows magnetic resonance imaging (MRI) of hollow-core microstructured fibers (HC-MFs), paving the way for combing MRI and optical bioimaging. Our approach is based on Layer-by-Layer assembly of oppositely charged polyelectrolytes and magnetite nanoparticles on the inner core surface of HC-MFs. Incorporation of magnetite nanoparticles into polyelectrolyte layers renders HC-MFs visible for MRI and induces the red-shift in their transmission spectra. Specifically, the transmission shifts up to 60 nm have been revealed for the several-layers composite coating along with the high-quality contrast of HC-MFs in MRI scans. Our results shed light on marrying fiber-based endoscopy with MRI that opens novel possibilities for minimally invasive clinical diagnostics and surgical procedures in vivo.Comment: 11 pages, 6 figure

Solar energy for green university: estimation of economic, environmental and image benefits

The paper considers the main components of the green university concept, the foreign experience of environmental transformation of higher education institutions, and the impact of eco-innovations implementation on strengthening universities’ position in the UI GreenMetric World University Rankings. The green strategy of Sumy State University, the results of its implementation, and prospects for improvement in terms of increasing renewable energy sources usage through the solar power plant installation are analysed. The effectiveness of the solar power plant investment project and the reduction of carbon dioxide emissions into the atmosphere by replacing conventional electricity with electricity generated by the solar power plant are estimated. It is proved that in addition to economic and environmental benefits, the implementation of the solar energy project will positively impact the university’s image at the national and international level

Comparative effectiveness of autologous hematopoietic stem cell transplant vs fingolimod, natalizumab, and ocrelizumab in highly active relapsing-remitting multiple sclerosis

Importance: Autologous hematopoietic stem cell transplant (AHSCT) is available for treatment of highly active multiple sclerosis (MS). Objective: To compare the effectiveness of AHSCT vs fingolimod, natalizumab, and ocrelizumab in relapsing-remitting MS by emulating pairwise trials. Design, Setting, and Participants: This comparative treatment effectiveness study included 6 specialist MS centers with AHSCT programs and international MSBase registry between 2006 and 2021. The study included patients with relapsing-remitting MS treated with AHSCT, fingolimod, natalizumab, or ocrelizumab with 2 or more years study follow-up including 2 or more disability assessments. Patients were matched on a propensity score derived from clinical and demographic characteristics. Exposure: AHSCT vs fingolimod, natalizumab, or ocrelizumab. Main outcomes: Pairwise-censored groups were compared on annualized relapse rates (ARR) and freedom from relapses and 6-month confirmed Expanded Disability Status Scale (EDSS) score worsening and improvement. Results: Of 4915 individuals, 167 were treated with AHSCT; 2558, fingolimod; 1490, natalizumab; and 700, ocrelizumab. The prematch AHSCT cohort was younger and with greater disability than the fingolimod, natalizumab, and ocrelizumab cohorts; the matched groups were closely aligned. The proportion of women ranged from 65% to 70%, and the mean (SD) age ranged from 35.3 (9.4) to 37.1 (10.6) years. The mean (SD) disease duration ranged from 7.9 (5.6) to 8.7 (5.4) years, EDSS score ranged from 3.5 (1.6) to 3.9 (1.9), and frequency of relapses ranged from 0.77 (0.94) to 0.86 (0.89) in the preceding year. Compared with the fingolimod group (769 [30.0%]), AHSCT (144 [86.2%]) was associated with fewer relapses (ARR: mean [SD], 0.09 [0.30] vs 0.20 [0.44]), similar risk of disability worsening (hazard ratio [HR], 1.70; 95% CI, 0.91-3.17), and higher chance of disability improvement (HR, 2.70; 95% CI, 1.71-4.26) over 5 years. Compared with natalizumab (730 [49.0%]), AHSCT (146 [87.4%]) was associated with marginally lower ARR (mean [SD], 0.08 [0.31] vs 0.10 [0.34]), similar risk of disability worsening (HR, 1.06; 95% CI, 0.54-2.09), and higher chance of disability improvement (HR, 2.68; 95% CI, 1.72-4.18) over 5 years. AHSCT (110 [65.9%]) and ocrelizumab (343 [49.0%]) were associated with similar ARR (mean [SD], 0.09 [0.34] vs 0.06 [0.32]), disability worsening (HR, 1.77; 95% CI, 0.61-5.08), and disability improvement (HR, 1.37; 95% CI, 0.66-2.82) over 3 years. AHSCT-related mortality occurred in 1 of 159 patients (0.6%). Conclusion: In this study, the association of AHSCT with preventing relapses and facilitating recovery from disability was considerably superior to fingolimod and marginally superior to natalizumab. This study did not find evidence for difference in the effectiveness of AHSCT and ocrelizumab over a shorter available follow-up time

Sustainable Development of EU countries: Assessment Methodology and Indicators

The aim of the article is to substantiate the methodology and indicators for assessment of sustainable development in EU countries at the present stage. The article suggests the use of certain indicators for assessment of sustainable development of EU countries: for economic evaluation – Index of Competitiveness and Index of Economic Freedom; for social evaluation — Life Quality Index, Human Development Index, Index of Knowledge Societies; for environmental evaluation — Environmental Sustainability Index and Environmental Efficiency Index. Each of the selected indexes in EU countries is analyzed. The methodology for calculating the ratio of the economic, social and environmental components of sustainable development for EU countries is presented. Emphasis is placed on the significant regional diversification of sustainable development and its components across EU countries, there identified countries of the strong, medium and weak sustainability

SBBOS AND PEPTIC ULCER DISEASE: EPIDEMIOLOGY, PATHOGENESIS, INFLUENCE ON CLINICAL MANIFESTATIONS AND THERAPEUTIC APPROACHES

The paper discusses the main aspects of the pathogenesis and incidence of SBBOS in the small intestine in patients with peptic ulcer of the duodenum associated with persistence of H. pylori; the effect of SBBOS on clinical manifestations. Diagnosis was made using the hydrogen breathing test with lactulose. The study found that SBBOS in patients with peptic ulcer associated with H. pylor is found in 62% and modifies the clinical pattern, prolonging the symptoms of gastric dyspepsia, provokes development of symptoms of intestinal dyspepsia, requires longer duration of treatment to achieve remission (clinical and endoscopic). This is the basis for its treatment

Influence of the obtaining method on the properties of amorphous aluminum compounds

© 2019 by the authors. Amorphous aluminum compounds are formed during the synthesis of the γ -Al2O3 catalyst precursor. Amorphous compounds influence on the alumina catalyst variously due to different physicochemical properties, which depend on the method of their preparation. In this research, the comparative analysis of physicochemical properties of amorphous aluminum compounds that were obtained by the precipitation method, the thermal decomposition of aluminum nitrate, and alcoxide hydrolysis product were studied. It is the first time that a new method for calculating of quantitative phase composition of amorphous aluminum compounds using the X-ray powder diffraction, thermogravimetric and differential scanning calorimetry analysis, mass-spectrometry, and CHN-analysis was described. Properties of obtaining samples were studied using scanning electron microscopy, low-temperature nitrogen adsorption, and temperature programmed desorption of ammonium analyses. The methods of precipitation and thermal decomposition of aluminum nitrate allows for obtaining non-porous samples consisting of a mixture of amorphous phases (hydroxide and basic salt) that contain the metals impurities and have low acidity of the oxides obtained from them. The highly porous amorphous alumina formed by the thermal decomposition of the alcoxide hydrolysis product with the least amount of impurities and a high acidity of the surface was observed

Influence of the obtaining method on the properties of amorphous aluminum compounds

© 2019 by the authors. Amorphous aluminum compounds are formed during the synthesis of the γ -Al2O3 catalyst precursor. Amorphous compounds influence on the alumina catalyst variously due to different physicochemical properties, which depend on the method of their preparation. In this research, the comparative analysis of physicochemical properties of amorphous aluminum compounds that were obtained by the precipitation method, the thermal decomposition of aluminum nitrate, and alcoxide hydrolysis product were studied. It is the first time that a new method for calculating of quantitative phase composition of amorphous aluminum compounds using the X-ray powder diffraction, thermogravimetric and differential scanning calorimetry analysis, mass-spectrometry, and CHN-analysis was described. Properties of obtaining samples were studied using scanning electron microscopy, low-temperature nitrogen adsorption, and temperature programmed desorption of ammonium analyses. The methods of precipitation and thermal decomposition of aluminum nitrate allows for obtaining non-porous samples consisting of a mixture of amorphous phases (hydroxide and basic salt) that contain the metals impurities and have low acidity of the oxides obtained from them. The highly porous amorphous alumina formed by the thermal decomposition of the alcoxide hydrolysis product with the least amount of impurities and a high acidity of the surface was observed