3,604 research outputs found
Synthesis of racemic and chiral BEDT-TTF derivatives possessing hydroxy groups and their achiral and chiral charge transfer complexes
Chiral molecular crystals built up by chiral molecules without inversion centers have attracted much interest owing to their versatile functionalities related to optical, magnetic, and electrical properties. However, there is a difficulty in chiral crystal growth due to the lack of symmetry. Therefore, we made the molecular design to introduce intermolecular hydrogen bonds in chiral crystals. Racemic and enantiopure bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF) derivatives possessing hydroxymethyl groups as the source of hydrogen bonds were designed. The novel racemic trans-vic-(hydroxymethyl)(methyl)-BEDT-TTF 1, and racemic and enantiopure trans-vic-bis(hydroxymethyl)-BEDT-TTF 2 were synthesized. Moreover, the preparations, crystal structure analyses, and electrical resistivity measurements of the novel achiral charge transfer salt θ21-[(S,S)-2]3[(R,R)-2]3(ClO4)2 and the chiral salt α’-[(R,R)-2]ClO4(H2O) were carried out. In the former θ21-[(S,S)-2]3[(R,R)-2]3(ClO4)2, there are two sets of three crystallographically independent donor molecules [(S,S)-2]2[(R,R)-2] in a unit cell, where the two sets are related by an inversion center. The latter α’-[(R,R)-2]ClO4(H2O) is the chiral salt with included solvent H2O, which is not isostructural with the reported chiral salt α’-[(S,S)-2]ClO4 without H2O, but has a similar donor arrangement. According to the molecular design by introduction of hydroxy groups and a ClO4− anion, many intermediate-strength intermolecular hydrogen bonds (2.6–3.0 Å) were observed in these crystals between electron donor molecules, anions, and included H2O solvent, which improve the crystallinity and facilitate the extraction of physical properties. Both salts are semiconductors with relatively low resistivities at room temperature and activation energies of 1.2 ohm cm with Ea = 86 meV for θ21-[(S,S)-2]3[(R,R)-2]3(ClO4)2 and 0.6 ohm cm with Ea = 140 meV for α'-[(R,R)-2]2ClO4(H2O), respectively. The variety of donor arrangements, θ21 and two kinds of α’-types, and their electrical conductivities of charge transfer complexes based upon the racemic and enantiopure (S,S)-2, and (R,R)-2 donors originates not only from the chirality, but also the introduced intermolecular hydrogen bonds involving the hydroxymethyl groups, perchlorate anion, and the included solvent H2O
A numerical study of the r-mode instability of rapidly rotating nascent neutron stars
The first results of numerical analysis of classical r-modes of {\it rapidly}
rotating compressible stellar models are reported. The full set of linear
perturbation equations of rotating stars in Newtonian gravity are numerically
solved without the slow rotation approximation. A critical curve of
gravitational wave emission induced instability which restricts the rotational
frequencies of hot young neutron stars is obtained. Taking the standard cooling
mechanisms of neutron stars into account, we also show the `evolutionary
curves' along which neutron stars are supposed to evolve as cooling and
spinning-down proceed. Rotational frequencies of stars suffering
from this instability decrease to around 100Hz when the standard cooling
mechanism of neutron stars is employed. This result confirms the results of
other authors who adopted the slow rotation approximation.Comment: 4 pages, 2 figures; MNRAS,316,L1(2000
On the relative expressiveness of higher-order session processes
By integrating constructs from the λ-calculus and the π-calculus, in higher-order process calculi exchanged values may contain processes. This paper studies the relative expressiveness of HOπ, the higher-order π-calculus in which communications are governed by session types. Our main discovery is that HO, a subcalculus of HOπ which lacks name-passing and recursion, can serve as a new core calculus for session-typed higher-order concurrency. By exploring a new bisimulation for HO, we show that HO can encode HOπ fully abstractly (up to typed contextual equivalence) more precisely and efficiently than the first-order session π-calculus (π). Overall, under session types, HOπ, HO, and π are equally expressive; however, HOπ and HO are more tightly related than HOπ and π
Supernovae from rotating stars
The present paper discusses the main physical effects produced by stellar
rotation on presupernovae, as well as observations which confirm these effects
and their consequences for presupernova models. Rotation critically influences
the mass of the exploding cores, the mass and chemical composition of the
envelopes and the types of supernovae, as well as the properties of the
remnants and the chemical yields. In the formation of gamma-ray bursts,
rotation and the properties of rotating stars appear as the key factor. In
binaries, the interaction between axial rotation and tidal effects often leads
to interesting and unexpected results. Rotation plays a key role in shaping the
evolution and nucleosynthesis in massive stars with very low metallicities
(metallicity below about the Small Magellanic Cloud metallicity down to
Population III stars). At solar and higher metallicities, the effects of
rotation compete with those of stellar winds. In close binaries, the
synchronisation process can lock the star at a high rotation rate despite
strong mass loss and thus both effects, rotation and stellar winds, have a
strong impact. In conclusion, rotation is a key physical ingredient of the
stellar models and of presupernova stages, and the evolution both of single
stars and close binaries. Moreover, important effects are expected along the
whole cosmic history.Comment: 36 pages, 15 figures, published in Handbook of Supernovae, A.W.
Alsabti and P. Murdin (eds), Springe
Wide-Scale Analysis of Human Functional Transcription Factor Binding Reveals a Strong Bias towards the Transcription Start Site
We introduce a novel method to screen the promoters of a set of genes with
shared biological function, against a precompiled library of motifs, and find
those motifs which are statistically over-represented in the gene set. The gene
sets were obtained from the functional Gene Ontology (GO) classification; for
each set and motif we optimized the sequence similarity score threshold,
independently for every location window (measured with respect to the TSS),
taking into account the location dependent nucleotide heterogeneity along the
promoters of the target genes. We performed a high throughput analysis,
searching the promoters (from 200bp downstream to 1000bp upstream the TSS), of
more than 8000 human and 23,000 mouse genes, for 134 functional Gene Ontology
classes and for 412 known DNA motifs. When combined with binding site and
location conservation between human and mouse, the method identifies with high
probability functional binding sites that regulate groups of biologically
related genes. We found many location-sensitive functional binding events and
showed that they clustered close to the TSS. Our method and findings were put
to several experimental tests. By allowing a "flexible" threshold and combining
our functional class and location specific search method with conservation
between human and mouse, we are able to identify reliably functional TF binding
sites. This is an essential step towards constructing regulatory networks and
elucidating the design principles that govern transcriptional regulation of
expression. The promoter region proximal to the TSS appears to be of central
importance for regulation of transcription in human and mouse, just as it is in
bacteria and yeast.Comment: 31 pages, including Supplementary Information and figure
R-mode oscillations of rapidly rotating Newtonian stars - A new numerical scheme and its application to the spin evolution of neutron stars
We have developed a new numerical scheme to solve r-mode oscillations of {\it
rapidly rotating polytropic stars} in Newtonian gravity. In this scheme, Euler
perturbations of the density, three components of the velocity are treated as
four unknown quantities together with the oscillation frequency. For the basic
equations of oscillations, the compatibility equations are used instead of the
linearized equations of motion.
By using this scheme, we have solved the classical r-mode oscillations of
rotational equilibrium sequences of polytropes with the polytropic indices and 1.5 for and 4 modes. Here is the rank of the
spherical harmonics . These results have been applied to investigate
evolution of uniformly rotating hot young neutron stars by considering the
effect of gravitational radiation and viscosity. We have found that the maximum
angular velocities of neutron stars are around 10-20% of the Keplerian angular
velocity irrespective of the softness of matter. This confirms the results
obtained from the analysis of r-modes with the slow rotation approximation
employed by many authors.Comment: LaTeX 12 pages with 19 figures, to be published in PR
Resource Sharing via Capability-Based Multiparty Session Types
Multiparty Session Types (MPST) are a type formalism used to model communication protocols among components in distributed systems, by specifying type and direction of data transmitted. It is standard for multiparty session type systems to use access control based on linear or affine types. While useful in offering strong guarantees of communication safety and session fidelity, linearity and affinity run into the well-known problem of inflexible programming, excluding scenarios that make use of shared channels or need to store channels in shared data structures.
In this paper, we develop capability-based resource sharing for multiparty session types. In this setting, channels are split into two entities, the channel itself and the capability of using it. This gives rise to a more flexible session type system, which allows channel references to be shared and stored in persistent data structures. We illustrate our type system through a producer-consumer case study. Finally, we prove that the resulting language satisfies type safety
Biphasic investigation of contact mechanics in natural human hips during activities
The aim of this study was to determine the cartilage contact mechanics and the associated fluid pressurisation of the hip joint under eight daily activities, using a three-dimensional finite element hip model with biphasic cartilage layers and generic geometries. Loads with spatial and temporal variations were applied over time and the time-dependent performance of the hip cartilage during walking was also evaluated. It was found that the fluid support ratio was over 90% during the majority of the cycles for all the eight activities. A reduced fluid support ratio was observed for the time at which the contact region slid towards the interior edge of the acetabular cartilage, but these occurred when the absolute level of the peak contact stress was minimal. Over 10 cycles of gait, the peak contact stress and peak fluid pressure remained constant, but a faster process of fluid exudation was observed for the interior edge region of the acetabular cartilage. The results demonstrate the excellent function of the hip cartilage within which the solid matrix is prevented from high levels of stress during activities owing to the load shared by fluid pressurisation. The findings are important in gaining a better understanding of the hip function during daily activities, as well as the pathology of hip degeneration and potential for future interventions. They provide a basis for future subject-specific biphasic investigations of hip performance during activities
The Dark Side of the Electroweak Phase Transition
Recent data from cosmic ray experiments may be explained by a new GeV scale
of physics. In addition the fine-tuning of supersymmetric models may be
alleviated by new O(GeV) states into which the Higgs boson could decay. The
presence of these new, light states can affect early universe cosmology. We
explore the consequences of a light (~ GeV) scalar on the electroweak phase
transition. We find that trilinear interactions between the light state and the
Higgs can allow a first order electroweak phase transition and a Higgs mass
consistent with experimental bounds, which may allow electroweak baryogenesis
to explain the cosmological baryon asymmetry. We show, within the context of a
specific supersymmetric model, how the physics responsible for the first order
phase transition may also be responsible for the recent cosmic ray excesses of
PAMELA, FERMI etc. We consider the production of gravity waves from this
transition and the possible detectability at LISA and BBO
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