Geotecnologias aplicadas à análise espaçotemporal do uso e da ocupação da terra na planície costeira de caravelas (BA)

O objetivo deste artigo é diagnosticar as principais formas de uso e ocupação da terra na Planície Costeira de Caravelas, no extremo sul da Bahia, ao longo dos anos de 1984, 1991, 2006 e 2011. Sua área é de aproximadamente 580 km², localizada entre os paralelos 17°37’52”S e 17°51’44”S e os meridianos 39°22’7” e 39°12’7.11” W de Greenwich. Para este diagnóstico, foram utilizadas como base as imagens orbitais do Satélite Landsat-TM, posteriormente integradas e processadas no Sistema de Informação Geográfica, pelo software ArcGis, por meio da classificação híbrida. Os resultados comprovam a gradativa expansão da área agrícola, da área urbana e da pastagem. Paralelamente há a redução das áreas ocupadas pelos corpos d’água e pelos Manguezais e brejos. O mapeamento realizado pretende contribuir com os estudos de evolução da paisagem e subsidiar melhores propostas de planejamento para o uso e a ocupação da terra nessa planície. Palavras-chave: uso e ocupação da terra, classificação híbrida, Caravelas, geotecnologias35

Impact of previous entrepreneurial experience on start­up evaluation & success

In this paper, a sample of 819 companies was tested for four different hypotheses. This dataset was collected and provided by Early Metrics. Throughout the literature, it is evident that several determinants influence start­up success. How exactly entrepreneurial experience contributes to this is not entirely clear, as there is also different literature contradicting each other. The effects of entrepreneurial experience on success were tested using several multiple regressions. We can conclude that the dataset used does not provide enough evidence that entrepreneurial experience affects the Early Metrics positioning. As a result, hypothesis (H1) entrepreneurial experience has a small but positive effect on start­up evaluation, is rejected. However, it must be said that such an effect cannot be excluded in general. The second hypothesis "(H2) Industry experience has a positive effect on start­up success" was examined and no significance could be shown in our dataset. Hypothesis (H3) that there is no significant difference between experienced and non­experienced founders in terms of team size, was analyzed and it can be concluded that we accept hypothesis H3. Due to the existing limitations within our dataset, no reliable statement can be made about the effect of entrepreneurial experience on yearly revenue. Some indicators and findings of this paper give an impetus for further research in this field, which is currently not characterized by a clear consensus. Therefore, it is important that academia continues to add to this field and also makes the implications for theory and practice accessible.Neste artigo, foi testada uma amostra de 819 empresas para quatro hipóteses diferentes. Este conjunto de dados foi recolhido e fornecido pela Early Metrics. Ao longo da literatura, é evidente que existem vários fatores determinantes que influenciam o sucesso. A forma exata como a experiência empresarial contribui para tal não é inteiramente clara, uma vez que também a literatura existente apresenta resultados contraditórios. Os efeitos da experiência empresarial no sucesso foram testados por meio de várias regressões. Podemos concluir que o conjunto de dados utilizado não fornece provas suficientes de que a experiência empresarial tenha um efeito sobre o posicionamento da Early Metrics. Como resultado, a hipótese (H1) de experiência empresarial tem um efeito pequeno mas positivo na avaliação inicial, é rejeitada. Contudo, deve dizer­se que tal efeito não pode ser excluído em geral. A segunda hipótese "(H2) A experiência da indústria tem um efeito positivo no sucesso do arranque" foi examinada e não pôde ser demonstrado qualquer significado no conjunto de dados analisados. A hipótese (H3) de que não há diferença significativa entre fundadores experientes e não experientes em termos de dimensão da equipa foi analisada e pode concluir­se que aceitamos a hipótese H3. Devido às limitações existentes nos dados considerados, não pode ser feita nenhuma declaração fiável sobre o efeito da experiência empresarial nas receitas anuais. Alguns indicadores e conclusões deste documento poderão motivar uma maior investigação neste campo, que atualmente não se caracteriza por ser consensual. Por conseguinte, é importante que a academia continue a desenvolver esforços neste campo e, também, a tornar as implicações para a teoria e para a prática acessíveis

Organisational decision-making processes behind incorporating autonomous task-performing technology and its impact on the future of work : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Management at Massey University, Manawatu, New Zealand

In recent years there have been mounting discussions among scholars, business people, governments, and scientists to understand the impact of emerging technologies such as automation and AI and their subsequent impact on the future of work. The concern for the future of work has primarily circulated around predictions estimating that up to half of the workforce, if not more, could be impacted by these technologies by the year 2030. Despite these predictions, there remains a need to understand the impact of emerging technologies on the future of work from the perspective of organisations, which has largely been omitted from previous research into this phenomenon. One of the prominent limitations throughout the literature circulates around the assumption that organisations will adopt these technologies. In light of this, there remains unanswered questions pertaining to the extent in which organisations will use emerging technology and whether adopting this technology inherently leads to job loss. It is vital to develop insights into what drives organisational decision-making processes to adopt these technologies to understand better the relationship between organisations, employees, and emerging technologies. When it comes to understanding the future of work, there remains a distinct difference between the impact on a job task versus an entire job. To address this, Autonomous Task Performing Technology (ATPT) has been adopted throughout this paper to reflect on how emerging technologies can impact employees to different extents. The present study was designed to understand the organisational decision-making process behind adopting ATPT and the subsequent impact on the future of work. Two primary participant groups were identified using purposive sampling with the snowball approach to address this research, which includes a total of 34 top managers and 10 union representatives. The 34 top manager participants are made up of 17 top managers from the public sector and 17 top managers from the private sector representing twenty-two different industries/ line of work across telecommunications, agriculture, finance, healthcare, business, education, transportation, technology, architecture, energy, technical services, engineering, retail, produce, manufacturing, finance, social services, marketing, research, legal, environment, and emergency services. The data with top managers were collected using in-depth semi-structured interviews with an average interview time of just over 1 hour which translated to over 34 hours in total of interview recordings. The 10 union representatives consisted of four participants from the public sector and six from the private sector covering six different industries spanning across finance, education, business, retail, transportation, and healthcare. Data collected with union representatives utilised the critical incident technique to understand the impact of ATPT on employees from incidents where organisations adopted ATPT with an average interview time of over 25 minutes. Although the design of this research was to understand the organisational decision-making processes behind adopting ATPT, it remained critical to understand this phenomenon from both perspectives of top managers and unions. Triangulation was used to compare and analyse the data using thematic analysis with the Framework method between top managers and union representatives. This approach provided valuable insight into how organisations adopt ATPT and how the impact is experienced by employees. The findings from this research place distinct emphasise on how ATPT does not inherently predetermine job loss. Rather, the findings capture the highly variable nature of organisational adoption of ATPT and the subsequent impact on the future of work through the development of the ATPT impact Framework. The ATPT impact Framework was conceptualised through the underpinning of three core themes in this research: organisational drivers behind ATPT adoption, scenarios of ATPT adoption, and the outcome of organisational adoption of ATPT on employees/ and the future of work. Ultimately, the future of work is not determined by the capabilities of ATPT, but rather by the ATPT impact Framework and the ethical responsibility of organisations to use ATPT responsibly. The impact of ATPT on the future of work does not fall on the shoulders of organisations alone, but rather requires an ongoing collaboration and open dialogue between organisations, government, policy makers, scholars, employees and unions to establish a form of good practice and ethical responsibility behind adopting ATPT as society continues to navigate through the challenges of how to effectively use ATPT

Untersuchungen über die antiinflammatorischen Eigenschaften des alpha-Melanozyten-stimulierenden-Hormones im Bezug auf die allergische Atemwegsentzündung

Erkrankungen des atopischen Formenkreises, wie beispielsweise das Asthma bronchiale, die Rhinitis allergica oder die atopische Dermatitis gehören heute zu den großen Volkskrankheiten der Industrienationen. Dabei sind ihre Inzidenzen und Prävalenzen in den letzten Jahren stetig angestiegen. Die zentrale Hypothese dieser Promotionsarbeit ist, dass das alpha-Melanozyten-stimulierende-Hormon (α-MSH) die allergische Atemwegsentzündung in vivo inhibiert. Die Lunge ist ein Organ, in dem sich schwerwiegende allergische Erkrankungen manifestieren können. Aufgrund der oftmals beschriebenen antiinflammatorischen Eigenschaften von α-MSH auf allergische Reaktionen der Haut, wurde die Hypothese aufgestellt, dass α-MSH auch bezüglich der allergischen Atemwegsentzündung antiinflammatorisch wirke. Um den Einfluss von α-MSH auf die allergische Atemwegsentzündung zu untersuchen, wurde ein neues Studienprotokoll in Anlehnung an ein bereits gut etabliertes Mausmodell für allergische Atemwegserkrankungen entworfen. BALB/c-Mäuse wurden systemisch (i. p.) mit dem Modellallergen Ovalbumin (OVA) immunisiert. Weiterhin erfolgte durch eine zweimalige Allergenprovokation mit einem OVA-Aerosol die Induktion der allergischen Entzündung in der Lunge. Einer Versuchsgruppe wurde zusätzlich vor allen Immunisierungs- und Provokationsschritten α-MSH i. v. appliziert. Als Negativkontrolle zu α-MSH wurde das Neuropeptid g-MSH verwendet, von dem bislang keine immunmodulatorischen Funktionen bekannt sind. Zur Quantifizierung der Atemwegshyperreagibilität wurde die non-invasive head-out Bodyplethysmographie herangezogen. Zudem erfolgte bei den Tieren eine broncho-alveoläre Lavage (BAL). In der BAL-Flüssigkeit wurden zum einen relevante Zytokine mittels ELISA-Techniken bestimmt, zum anderen wurde eine mikroskopische Differenzierung des Zellprofils der BAL durchgeführt. Ferner wurden zur Darstellung des pulmonalen Entzündungsinfiltrates Kryoschnittpräparate von den Lungen der Versuchstiere angefertigt. Weiterhin wurde mittels FACS-Analyse die Expression des für α-MSH spezifischen Melanocortin-Rezeptors MC-1 auf BAL-Makrophagen, sowie die Expression des Makrophagen-Aktvierungsmarkers MAC-3 untersucht. Mittels Radioimmunoassay erfolgte darüber hinaus erstmalig der Nachweis von α-MSH in der BAL. Außerdem wurde der Verlauf der α-MSH-Konzentrationen nach einer aerosolischen Allergenprovokation über 16 Tage gemessen. Des Weiteren wurden mit Hilfe von ELISA-Techniken relevante Immunglobuline aus dem peripheren Blut bestimmt. Die Analysen ergaben folgende Ergebnisse: In der BAL-Flüssigkeit von Tieren, die parallel zu dem Sensibilisierungsprotokoll mit α-MSH behandelt wurden, waren die Konzentrationen von proinflammatorischen Zytokinen, wie IL-4 oder IL-13, signifikant erniedrigt, im Vergleich zu nur OVA sensibilisierten/provozierten (OVA-Gruppe) Tieren. Im Gegensatz dazu waren die Konzentrationen des antiinflammatorischen Zytokins IL-10 in der α-MSH-Gruppe signifikant erhöht. Des Weiteren konnte in der α-MSH-Gruppe ein signifikanter Abfall der Anzahl von eosinophilen Granulozyten in der BAL-Flüssigkeit, verglichen mit Tieren ohne α-MSH Behandlung, nachgewiesen werden. Ebenso zeigten die mit α-MSH behandelten Tiere nicht die sonst bei der allergischen Atemwegserkrankung zu findende peribronchiale entzündliche Infiltration. Die Auswertung der Bodyplethysmographie ergab allerdings nur eine tendenzielle Verringerung der Atemwegshyperreagibilität in der α-MSH-Gruppe. Hingegen konnte bei der Analyse der Serum-Immunglobuline ein signifikanter Abfall der Konzentrationen von anti-OVA spezifischen Antikörpern bei der α-MSH-Gruppe im Vergleich zur OVA-Gruppe nachgewiesen werden. In früheren Studien gab es weitreichende Hinweise darauf, dass die antiinflammatorischen Wirkungen von α-MSH IL-10 vermittelt sein könnten. Diesbezüglich waren bei den Ergebnissen dieser Promotionsarbeit erhöhte IL-10-Konzentrationen in der BAL-Flüssigkeit α-MSH behandelter Tiere aufgefallen. Um zu untersuchen, ob die α-MSH vermittelten Effekte im vorliegenden Tiermodell ebenfalls IL-10 vermittelt seien, etablierten wir daher ein identisches Studienprotokoll mit IL-10-knock-out-Mäusen. Bei den IL-10-knock-out-Mäusen konnte keiner der oben aufgeführten antiinflammatorischen Effekte von α-MSH nachgewiesen werden. Ein IL-10 vermittelter Wirkmechanismus von α-MSH erscheint demnach wahrscheinlich

IMPLEMENTASI MODEL ARIMA-GARCH TERHADAP PERAMALAN KONVERSI MATA UANG YEN KE RUPIAH

Transaksi jual beli selalu digunakan oleh manusia guna memenuhi kebutuhannya. Salah satu alat transaksi yang digunakan adalah uang. Setiap negara memiliki mata uangnya tersendiri termasuk Jepang, dengan mata uangnya yaitu Yen, dimana Yen terus mengalami penurunan yang signifikan sepanjang April 2022 melebihi 5-10%. Oleh karena itu, perlu adanya antisipasi terhadap laju kenaikan/penurunan nilai mata uang Yen. Metode yang digunakan adalah metode ARIMA-GARCH. Penelitian ini memiliki tujuan untuk mendapatkan model terbaik untuk konversi mata uang Yen ke Rupiah dari Januari 2001 hingga Juni 2023, serta mendapatkan hasil peramalan selama 12 bulan mendatang dari konversi mata uang tersebut. Jenis penelitian yang dipakai pada penelitian ini yaitu penelitian kuantitatif. Data yang dipakai pada penelitian ini adalah data konversi mata uang Yen ke Rupiah periode harian berupa deret waktu. Setelah dilakukan pengujian dan peramalan, didapatkan kesimpulan bahwa model yang paling tepat untuk menganalisis data di penelitian ini adalah model ARIMA(3,1,3)-GARCH(1,1). Hal ini dikarenakan model tersebut dapat mengatasi adanya homogenitas pada data yang ada. Konversi mata uang Yen ke Rupiah dari bulan Agustus 2022 hingga Juli 2023 dapat diramalkan memiliki fluktuasi, serta menghasilkan nilai MAPE sebesar 19.29%, dimana hal tersebut menandakan bahwa tingkat presisi dari model ARIMA(3,1,3)-GARCH(1,1) cukup baik untuk digunakan kepada data konversi tersebut. ***** Transaksi jual beli selalu digunakan oleh manusia guna memenuhi kebutuhannya. Salah satu alat transaksi yang digunakan adalah uang. Setiap negara memiliki mata uangnya tersendiri termasuk Jepang, dengan mata uangnya yaitu Yen, dimana Yen terus mengalami penurunan yang signifikan sepanjang April 2022 melebihi 5-10%. Oleh karena itu, perlu adanya antisipasi terhadap laju kenaikan/penurunan nilai mata uang Yen. Metode yang digunakan adalah metode ARIMA-GARCH. Penelitian ini memiliki tujuan untuk mendapatkan model terbaik untuk konversi mata uang Yen ke Rupiah dari Januari 2001 hingga Juni 2023, serta mendapatkan hasil peramalan selama 12 bulan mendatang dari konversi mata uang tersebut. Jenis penelitian yang dipakai pada penelitian ini yaitu penelitian kuantitatif. Data yang dipakai pada penelitian ini adalah data konversi mata uang Yen ke Rupiah periode harian berupa deret waktu. Setelah dilakukan pengujian dan peramalan, didapatkan kesimpulan bahwa model yang paling tepat untuk menganalisis data di penelitian ini adalah model ARIMA(3,1,3)-GARCH(1,1). Hal ini dikarenakan model tersebut dapat mengatasi adanya homogenitas pada data yang ada. Konversi mata uang Yen ke Rupiah dari bulan Agustus 2022 hingga Juli 2023 dapat diramalkan memiliki fluktuasi, serta menghasilkan nilai MAPE sebesar 19.29 %, dimana hal tersebut menandakan bahwa tingkat presisi dari model ARIMA(3,1,3)-GARCH(1,1) cukup baik untuk digunakan kepada data konversi tersebut

Untersuchungen über die antiinflammatorischen Eigenschaften des alpha-Melanozyten-stimulierenden-Hormones im Bezug auf die allergische Atemwegsentzündung

Erkrankungen des atopischen Formenkreises, wie beispielsweise das Asthma bronchiale, die Rhinitis allergica oder die atopische Dermatitis gehören heute zu den großen Volkskrankheiten der Industrienationen. Dabei sind ihre Inzidenzen und Prävalenzen in den letzten Jahren stetig angestiegen. Die zentrale Hypothese dieser Promotionsarbeit ist, dass das alpha-Melanozyten-stimulierende-Hormon (α-MSH) die allergische Atemwegsentzündung in vivo inhibiert. Die Lunge ist ein Organ, in dem sich schwerwiegende allergische Erkrankungen manifestieren können. Aufgrund der oftmals beschriebenen antiinflammatorischen Eigenschaften von α-MSH auf allergische Reaktionen der Haut, wurde die Hypothese aufgestellt, dass α-MSH auch bezüglich der allergischen Atemwegsentzündung antiinflammatorisch wirke. Um den Einfluss von α-MSH auf die allergische Atemwegsentzündung zu untersuchen, wurde ein neues Studienprotokoll in Anlehnung an ein bereits gut etabliertes Mausmodell für allergische Atemwegserkrankungen entworfen. BALB/c-Mäuse wurden systemisch (i. p.) mit dem Modellallergen Ovalbumin (OVA) immunisiert. Weiterhin erfolgte durch eine zweimalige Allergenprovokation mit einem OVA-Aerosol die Induktion der allergischen Entzündung in der Lunge. Einer Versuchsgruppe wurde zusätzlich vor allen Immunisierungs- und Provokationsschritten α-MSH i. v. appliziert. Als Negativkontrolle zu α-MSH wurde das Neuropeptid g-MSH verwendet, von dem bislang keine immunmodulatorischen Funktionen bekannt sind. Zur Quantifizierung der Atemwegshyperreagibilität wurde die non-invasive head-out Bodyplethysmographie herangezogen. Zudem erfolgte bei den Tieren eine broncho-alveoläre Lavage (BAL). In der BAL-Flüssigkeit wurden zum einen relevante Zytokine mittels ELISA-Techniken bestimmt, zum anderen wurde eine mikroskopische Differenzierung des Zellprofils der BAL durchgeführt. Ferner wurden zur Darstellung des pulmonalen Entzündungsinfiltrates Kryoschnittpräparate von den Lungen der Versuchstiere angefertigt. Weiterhin wurde mittels FACS-Analyse die Expression des für α-MSH spezifischen Melanocortin-Rezeptors MC-1 auf BAL-Makrophagen, sowie die Expression des Makrophagen-Aktvierungsmarkers MAC-3 untersucht. Mittels Radioimmunoassay erfolgte darüber hinaus erstmalig der Nachweis von α-MSH in der BAL. Außerdem wurde der Verlauf der α-MSH-Konzentrationen nach einer aerosolischen Allergenprovokation über 16 Tage gemessen. Des Weiteren wurden mit Hilfe von ELISA-Techniken relevante Immunglobuline aus dem peripheren Blut bestimmt. Die Analysen ergaben folgende Ergebnisse: In der BAL-Flüssigkeit von Tieren, die parallel zu dem Sensibilisierungsprotokoll mit α-MSH behandelt wurden, waren die Konzentrationen von proinflammatorischen Zytokinen, wie IL-4 oder IL-13, signifikant erniedrigt, im Vergleich zu nur OVA sensibilisierten/provozierten (OVA-Gruppe) Tieren. Im Gegensatz dazu waren die Konzentrationen des antiinflammatorischen Zytokins IL-10 in der α-MSH-Gruppe signifikant erhöht. Des Weiteren konnte in der α-MSH-Gruppe ein signifikanter Abfall der Anzahl von eosinophilen Granulozyten in der BAL-Flüssigkeit, verglichen mit Tieren ohne α-MSH Behandlung, nachgewiesen werden. Ebenso zeigten die mit α-MSH behandelten Tiere nicht die sonst bei der allergischen Atemwegserkrankung zu findende peribronchiale entzündliche Infiltration. Die Auswertung der Bodyplethysmographie ergab allerdings nur eine tendenzielle Verringerung der Atemwegshyperreagibilität in der α-MSH-Gruppe. Hingegen konnte bei der Analyse der Serum-Immunglobuline ein signifikanter Abfall der Konzentrationen von anti-OVA spezifischen Antikörpern bei der α-MSH-Gruppe im Vergleich zur OVA-Gruppe nachgewiesen werden. In früheren Studien gab es weitreichende Hinweise darauf, dass die antiinflammatorischen Wirkungen von α-MSH IL-10 vermittelt sein könnten. Diesbezüglich waren bei den Ergebnissen dieser Promotionsarbeit erhöhte IL-10-Konzentrationen in der BAL-Flüssigkeit α-MSH behandelter Tiere aufgefallen. Um zu untersuchen, ob die α-MSH vermittelten Effekte im vorliegenden Tiermodell ebenfalls IL-10 vermittelt seien, etablierten wir daher ein identisches Studienprotokoll mit IL-10-knock-out-Mäusen. Bei den IL-10-knock-out-Mäusen konnte keiner der oben aufgeführten antiinflammatorischen Effekte von α-MSH nachgewiesen werden. Ein IL-10 vermittelter Wirkmechanismus von α-MSH erscheint demnach wahrscheinlich

Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case

Bisphosphonates are drugs indicated for the treatment of bone metabolic diseases or malignant hypercalcemia. They are generally well-tolerated drugs, however, recent reports have described osteonecrosis of the jaw bones as a potentially serious complication related to the long-term use of these drugs. We report a case of severe osteonecrosis in a 52-years-old white woman that was taking bisphosphonates (zoledronic acid and alendronate) for the management of osteoporosis. Following a long exposure to these drugs and after being subjected to multiples exodontias, developed bisphosphonate-related osteonecrosis of the jaw compromising the whole maxilla and that extended toward the base of skull. Due to the extent of osteonecrosis, total maxillectomy and removal of all adjacent necrotic bone were planned guided by ultraviolet light. fluorescence. This case illustrates that if not treated correctly, bisphosphonate-related osteonecrosis of the jaw may cause significant morbidity, affect the quality of life and can eventually produce significant morbidity with the dissemination to noble structures and potentially causing life-threatening complications

Canadians studying medicine abroad and their journey to secure postgraduate training in Canada or the United States

Background: From national and international workforce perspectives, Canadians studying medicine abroad (CSAs) are a growing provider group. Some were born in Canada whereas others immigrated as children. They study medicine in various countries, often attempting both American and Canadian medical licensure pathways. Methods: Using data from the Educational Commission for Foreign Medical Graduates (ECFMG) and the Medical Council of Canada (MCC), we looked at CSAs who attempted to secure residency positions in both Canada and the United States. We detailed the CSAs’ countries of birth and medical education. We tracked these individuals through their postgraduate education programs to enumerate their success rate and categorize the geographic locations of their training. Results: The majority of CSAs study medicine in one of 10 countries. The remainder are disbursed across 88 other countries. Most CSAs were born in Canada (62%). Approximately 1/3 of CSA from the 2004-2016 cohort had no record of entering a residency program in Canada or the United States (U.S.). Recently graduated CSAs were most likely to secure residency training in Ontario and New York. Conclusion: Many CSAs attempt to secure residency training in both Canada and the U.S. Quantifying success rates may be helpful for Canadians thinking about studying medicine abroad. Understanding the educational pathways of CSAs will be useful for physician labour workforce planning

Proposal of geoenvironmental zoning as a subsidy to the land us and occupation planning in the Whale Coast Region (Bahia)

Orientador: Regina Célia de OliveiraTese (doutorado) - Universidade Estadual de Campinas, Instituto de GeociênciasResumo: A funcionalidade dos ambientes naturais é alterada pelas ações humanas em um ritmo mais intenso que aquele normalmente produzido pela própria natureza. Quando não planejadas, tais alterações proporcionam uma série de desequilíbrios funcionais que, muitas vezes acarretam consequências drásticas à vida humana e à própria natureza. Exemplos desses desequilíbrios ambientais podem ser visualizados na maioria dos municípios situados ao longo do litoral brasileiro. Estes, nas últimas décadas sofreram com a implantação imprópria de novas formas de uso e ocupação da terra. O desmatamento, o lançamento de efluentes nos cursos de água, o aterramento e a construção em zonas costeiras denunciam a falta de preocupação com o ordenamento do território. O modelo de urbanização regente no cenário nacional, imprime aos limites da costa uma relação de uso secular, onde o processo de urbanização reflete em diferentes níveis de impactos no comprometimento do funcionamento dos sistemas naturais costeiros, refletindo na maximização de processos de inundações e na completa instabilidade dos ecossistemas associados aqueles espaços. Ao considerarmos o quadro de fragilidade natural e a relação de uso das terras no estado da Bahia e de forma mais especifica na Região da Costa das Baleias, esta pesquisa objetiva colaborar com as ações de planejamento do uso e ocupação da Região Costa das Baleias, a partir da abordagem sistêmica, apresentando como produto síntese um zoneamento em escala 1:100.000 com base na proposta de Rodriguez, Silva e Cavalcanti (2004). Sob a visão sistêmica, procurou-se caracterizar os principais sistemas naturais existentes, com um destaque para os sistemas de Tabuleiros Costeiros. Foram também analisados os sistemas antrópicos presentes na Região Costa das Baleias que, ao abrangerem também a evolução antrópica, sinalizaram a alteração do ambiente como um todo. Por fim, o estado ambiental, a vulnerabilidade ambiental e o zoneamento proposto neste trabalho poderão contribuir no auxílio aos planos de uso e ocupação das terras e servir de apoio ao planejamento urbano e ambiental na área, visando a minimização do quadro de impactos ambientais negativos, na busca por um desenvolvimento compatível com as necessidades antrópicas e o equilíbrio dos sistemas ambientais presentesAbstract: The functionality of the natural environment is modified by human actions in a a faster rhythm than that normally produced by nature itself. When unplanned, these changes provide a number of functional imbalances that often entail drastic consequences to human life and nature. Examples of these environmental imbalances can be viewed in most cities located along the Brazilian coast. These, in recent decades suffered from the improper implementation of new forms of use and occupation of land. Deforestation, the discharge of effluents into waterways, grounding and construction in coastal areas denounce the lack of concern for land use planning. The conductor urbanization model on the national scene, print limits the coast a secular use interface, where the process of urbanization reflected in different levels of impact on the commitment of the systemic functioning of coastal natural systems, reflecting on the maximization of flooding processes and full instability of ecosystems associated with those areas. As we consider the natural fragility framework and land use relation in the state of Bahia and more specifically in the Whale Coast Region , this research aims to collaborate with the actions of planning the use and occupation of the Coastal Whales Region, the From the systemic approach, presenting as a synthesis product a 1: 100,000 scale zoning based on the Rodriguez, Silva and Cavalcanti (2004) proposal. Under the systemic view, we tried to characterize the main existing natural systems, with a emphasis for the coastal tableland systems. Also analyzed were the anthropic systems present in the Whales Coastal Region that, when they also covered the anthropic evolution, signaled the alteration of the environment as a whole. Finally, the environmental state, environmental vulnerability and zoning proposed in this study may contribute to the land use plans and support urban and environmental planning in the area, aiming at minimizing the negative environmental impact, of the search by a development compatible with the anthropic needs and the balance of the present environmental systemsDoutoradoAnálise Ambiental e Dinâmica TerritorialDoutor em Geografia2013/25003-2FAPES