Enhancement of sustainable land soil resource management in agriculture - E2SOILAGRI. Project mid-term implementation review

This is a mid-term report for the NIBIO assignment in “E2SOILAGRI”. The report gives information on the process and the deliveries for the Latvian partners in the project and includes remarks from the review team. This task is defined as sub-activity 4.1 in the Terms of Reference for the NIBIO assignment.publishedVersio

Motor development and gender differences for children between the ages of 5 and 15

Hensikten med denne studien var å undersøke barn og ungdoms motoriske utvikling, samt undersøke eventuell kjønnsforskjell i utførelsen av ulike motoriske oppgaver. Resultatene viser at det er en progresjon i motorisk kompetanse fra alderen 5-15 år i de respektive deltestene, der motoriske kompetanse bedres ved økende alder fra 5-15 år. Resultatene viser også til at jentene hadde signifikant bedre resultat i to av de finmotoriske deltestene, tre kubber på snor (Movement ABC) og plassere pinner på brett (Movement ABC). Mens guttene hadde signifikant bedre ferdighet i en av de grovmotoriske testene, gå/løpe i sløyfe (Test of Motor Competence)

Letter to the Editor

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Experiences with energy drink consumption among Norwegian adolescents

The objective of the present study was to describe adolescents’ habits and experiences with energy drink (ED) consumption and the relation to the amount of ED consumed. We used the national cross-sectional study Ungdata, conducted in 2015–16 in Norway. A total of 15 913 adolescents aged 13–19 years answered questions about ED consumption related to the following topics: reasons for, experiences with, habits and parental attitudes. The sample comprised only adolescents reporting to be ED consumers. We estimated the association between the responses and the average daily consumption of ED in multiple regression models. Those who consumed ED ‘to concentrate’ or ‘to perform better in school’ consumed on average 73⋅1 (CI 65⋅8, 80⋅3) and 112⋅0 (CI 102⋅7, 121⋅2) ml more daily, respectively, than those who did not consume ED for these reasons. Up to 80 % of the adolescents reported that ‘my parents think it is OK that I drink energy drink’, but at the same time almost 50 % reported that ‘my parents say that I shouldn't drink energy drink’. Apart from increased endurance and feeling stronger, both desired and adverse effects of ED consumption were reported. Our findings indicate that the expectation created by the ED companies have great influence on the adolescents’ consumption rate and that parental attitudes towards ED have little to no influence on the adolescents’ consumption rate.publishedVersio

Enhancement of sustainable land soil resource management in agriculture - E2SOILAGRI. Final project implementation review (PIR)

This is the final report for the NIBIO assignment in E2SOILAGRI. The report is a final project implementation review (PIR) assessing implementation results according to the planned results for E2SOILAGRI and the recommendations provided in the mid-term PIR is also be assessed. The review is sub-activity 4.1 in E2SOILAGRI project.Enhancement of sustainable land soil resource management in agriculture - E2SOILAGRI. Final project implementation review (PIR)publishedVersio

Klimatilpasning av høstkornproduksjon i Østfold

Klimaendringer er i Norge ventet å gi en lenger vekstsesong som kan øke muligheten for å etablere høstkorn i tide om høsten og dermed øke høstkornarealet. Det er også forventet mer ekstremvær som store nedbørsmengder og tørke. Det kan gi utfordringer i forhold til etablering av høstkornet, påvirke planteproduksjonen og behovet for tilpasninger. Dette faktaarket omhandler strategier for klimatilpasning for høstkornproduksjon på leirjord i Østfold.Klimatilpasning av høstkornproduksjon i ØstfoldpublishedVersio

Klimatilpasning av byggdyrking i Hedmark

Klimaendringer er i Norge ventet å gi en lenger vekstsesong, men også risiko for mer ekstremvær som tørke og episoder med store nedbørsmengder. Dette vil påvirke planteproduksjonen og behovet for tilpasninger. Dette faktaarket omhandler strategier for klimatilpasning for byggdyrking på lettleire i Hedmark.Klimatilpasning av byggdyrking i HedmarkpublishedVersio

Reduction in omission events after implementing a Rapid Response System: a mortality review in a department of gastrointestinal surgery

Background Hospitals worldwide have implemented Rapid Response Systems (RRS) to facilitate early recognition and prompt response by trained personnel to deteriorating patients. A key concept of this system is that it should prevent ‘events of omission’, including failure to monitor patients’ vital signs, delayed detection, and treatment of deterioration and delayed transfer to an intensive care unit. Time matters when a patient deteriorates, and several in-hospital challenges may prevent the RRS from functioning adequately. Therefore, we must understand and address barriers for timely and adequate responses in cases of patient deterioration. Thus, this study aimed to investigate whether implementing (2012) and developing (2016) an RRS was associated with an overall temporal improvement and to identify needs for further improvement by studying; patient monitoring, omission event occurrences, documentation of limitation of medical treatment, unexpected death, and in-hospital- and 30-day mortality rates. Methods We performed an interprofessional mortality review to study the trajectory of the last hospital stay of patients dying in the study wards in three time periods (P1, P2, P3) from 2010 to 2019. We used non-parametric tests to test for differences between the periods. We also studied overall temporal trends in in-hospital- and 30-day mortality rates. Results Fewer patients experienced omission events (P1: 40%, P2: 20%, P3: 11%, P = 0.01). The number of documented complete vital sign sets, median (Q1,Q3) P1: 0 (0,0), P2: 2 (1,2), P3: 4 (3,5), P = 0.01) and intensive care consultations in the wards ( P1: 12%, P2: 30%, P3: 33%, P = 0.007) increased. Limitations of medical treatment were documented earlier (median days from admission were P1: 8, P2: 8, P3: 3, P = 0.01). In-hospital and 30-day mortality rates decreased during this decade (rate ratios 0.95 (95% CI: 0.92–0.98) and 0.97 (95% CI: 0.95–0.99)). Conclusion The RRS implementation and development during the last decade was associated with reduced omission events, earlier documentation of limitation of medical treatments, and a temporal reduction in the in-hospital- and 30-day mortality rates in the study wards. The mortality review is a suitable method to evaluate an RRS and provide a foundation for further improvement.publishedVersio

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

Ductal carcinoma in situ; Tumor microenvironment; Whole genome sequencingCarcinoma ductal in situ; Microambiente tumoral; Secuenciación del genoma completoCarcinoma ductal in situ; Microambient tumoral; Seqüenciació del genoma completDuctal carcinoma in situ (DCIS) is the most common precursor of invasive breast cancer (IBC), with variable propensity for progression. We perform multiscale, integrated molecular profiling of DCIS with clinical outcomes by analyzing 774 DCIS samples from 542 patients with 7.3 years median follow-up from the Translational Breast Cancer Research Consortium 038 study and the Resource of Archival Breast Tissue cohorts. We identify 812 genes associated with ipsilateral recurrence within 5 years from treatment and develop a classifier that predicts DCIS or IBC recurrence in both cohorts. Pathways associated with recurrence include proliferation, immune response, and metabolism. Distinct stromal expression patterns and immune cell compositions are identified. Our multiscale approach employed in situ methods to generate a spatially resolved atlas of breast precancers, where complementary modalities can be directly compared and correlated with conventional pathology findings, disease states, and clinical outcome.This publication is part of the HTAN (Human Tumor Atlas Network) Consortium paper package. A list of HTAN members is available at humantumoratlas.org/htan-authors/. R01 CA185138-01 (E.S.H.); U2C CA-17-035 Pre-Cancer Atlas (PCA) Research Centers (E.S.H., R.B.W., C.M., K.P., G.A.C., K.O.); UO1 CA214183 (J.R.M.); DOD BC132057 (E.S.H., C.M.); BCRF 19-074 (E.S.H.); BCRF 19-028 (G.A.C.); PRECISION CRUK Grand Challenge (E.S.H.); R01CA193694 (R.B.W., G.A.C.), BCRF PPI-18-006 (R.B.W.). AEI RYC2019- 026576-I, "LaCaixa" Foundation LCF/PR/PR17/51120011 (J.A.S.). S.H.S. was supported by the Lundbeck Foundation (R288-2018-35) and the Danish Cancer Society (R229-A13616). K.E.H. was supported by a CIHR Banting Postdoctoral Fellowship. TBCRC 038 was conducted by the TBCRC, which receives major funding support from The Breast Cancer Research Foundation and Susan G. Komen. Some results in this paper are based upon data generated by the TCGA Research Network

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

Ductal carcinoma in situ (DCIS) is the most common precursor of invasive breast cancer (IBC), with variable propensity for progression. We perform multiscale, integrated molecular profiling of DCIS with clinical outcomes by analyzing 774 DCIS samples from 542 patients with 7.3 years median follow-up from the Translational Breast Cancer Research Consortium 038 study and the Resource of Archival Breast Tissue cohorts. We identify 812 genes associated with ipsilateral recurrence within 5 years from treatment and develop a classifier that predicts DCIS or IBC recurrence in both cohorts. Pathways associated with recurrence include proliferation, immune response, and metabolism. Distinct stromal expression patterns and immune cell compositions are identified. Our multiscale approach employed in situ methods to generate a spatially resolved atlas of breast precancers, where complementary modalities can be directly compared and correlated with conventional pathology findings, disease states, and clinical outcome