4,092 research outputs found
HIGH PRICE VOLATILITY AND SPILLOVER EFFECTS IN ENERGY MARKETS
Replaced with revised version of paper 07/22/11.Asymmetric shocks, energy markets, oil, spillover effects, volatility, Marketing, Resource /Energy Economics and Policy, GARCH,
The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review)
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease. Patients with severe chronic obstructive pulmonary disease who are symptomatic and who suffer repeated exacerbations are recommended to add inhaled corticosteroids to their bronchodilator treatment. However, the benefits and risks of adding inhaled corticosteroid to tiotropium and long-acting beta2-agonists for the treatment of chronic obstructive pulmonary disease are unclear.ObjectivesTo assess the relative effects of adding inhaled corticosteroids to tiotropium and long-acting beta2-agonists treatment in patients with chronic obstructive pulmonary disease.Search strategyWe searched the Cochrane Airways Group Specialised Register of trials (February 2011) and reference lists of articles.Selection criteriaWe included parallel group, randomised controlled trials of three months or longer comparing inhaled corticosteroid and long-acting beta(2)-agonist combination therapy in addition to inhaled tiotropium against tiotropium and long-acting beta2-agonist treatment for patients with chronic obstructive pulmonary disease (COPD).Data collection and analysisTwo review authors independently assessed trials for inclusion and then extracted data on trial quality and the outcome results. We contacted study authors for additional information. We collected information on adverse effects from the trials.Main resultsOne trial (293 patients) was identified comparing tiotropium in addition to inhaled corticosteroid and long-acting beta(2)-agonist combination therapy to tiotropium plus long-acting beta2-agonist. The study was of good methodological quality, however it suffered from high and uneven withdrawal rates between the treatment arms. There is currently insufficient evidence to know how much difference the addition of inhaled corticosteroids makes to people who are taking tiotropium and a long-acting beta(2)-agonist for COPD.Authors' conclusionsThe relative efficacy and safety of adding inhaled corticosteroid to tiotropium and a long-acting beta(2)-agonist for chronic obstructive pulmonary disease patients remains uncertain and additional trials are required to answer this question
Second Line of Defense Virtual Private Network Guidance for Deployed and New CAS Systems
This paper discusses the importance of remote access via virtual private network (VPN) for the Second Line of Defense (SLD) Central Alarm System (CAS) sites, the requirements for maintaining secure channels while using VPN and implementation requirements for current and future sites
Sediment Graphs Based on Entropy Theory
Using the entropy theory, this paper derives an instantaneous unit sediment graph (IUSG or USG) to determine sediment discharge and the relation between sediment yield and runoff volume. The derivation of IUSG requires an expression of the effective sediment erosion intensity whose relation with rainfall is revisited. The entropy theory provides an efficient way to estimate the parameters involved in the derivations. Sediment discharge is also computed using the instantaneous unit hydrograph (IUH), which can also be derived using the entropy theory. This method works as well as the IUSG method, especially when the peak sediment discharge and peak runoff occur at the same time. The entropy theory yields the probability distribution of sediment yield and of sediment discharge, which can then be used to estimate uncertainty in sediment yield prediction
Periodic Optical Variability of Radio Detected Ultracool Dwarfs
A fraction of very low mass stars and brown dwarfs are known to be radio
active, in some cases producing periodic pulses. Extensive studies of two such
objects have also revealed optical periodic variability and the nature of this
variability remains unclear. Here we report on multi-epoch optical photometric
monitoring of six radio detected dwarfs, spanning the M8 - L3.5 spectral
range, conducted to investigate the ubiquity of periodic optical variability in
radio detected ultracool dwarfs. This survey is the most sensitive ground-based
study carried out to date in search of periodic optical variability from
late-type dwarfs, where we obtained 250 hours of monitoring, delivering
photometric precision as low as 0.15%. Five of the six targets exhibit
clear periodicity, in all cases likely associated with the rotation period of
the dwarf, with a marginal detection found for the sixth. Our data points to a
likely association between radio and optical periodic variability in
late-M/early-L dwarfs, although the underlying physical cause of this
correlation remains unclear. In one case, we have multiple epochs of monitoring
of the archetype of pulsing radio dwarfs, the M9 TVLM 513-46546, spanning a
period of 5 years, which is sufficiently stable in phase to allow us to
establish a period of 1.95958 0.00005 hours. This phase stability may be
associated with a large-scale stable magnetic field, further strengthening the
correlation between radio activity and periodic optical variability. Finally,
we find a tentative spin-orbit alignment of one component of the very low mass
binary LP 349-25.Comment: Accepted to The Astrophysical Journal; 22 pages; 12 figure
An Experimental and Modeling Study on the Response to Varying Pore Pressure and Reservoir Fluids in the Morrow A Sandstone
In mature oil fields undergoing enhanced oil recovery methods, such as CO2 injection, monitoring the reservoir changes becomes important. To understand how reservoir changes influence compressional wave (P) and shear wave (S) velocities, we conducted laboratory core experiments on five core samples taken from the Morrow A sandstone at Postle Field, Oklahoma. The laboratory experiments measured P- and S-wave velocities as a function of confining pressure, pore pressure, and fluid type (which included CO2 in the gas and supercritical phase). P-wave velocity shows a response that is sensitive to both pore pressure and fluid saturation. However, S-wave velocity is primarily sensitive to changes in pore pressure. We use the fluid and pore pressure response measured from the core samples to modify velocity well logs through a log facies model correlation. The modified well logs simulate the brine- and CO2-saturated cases at minimum and maximum reservoir pressure and are inputs for full waveform seismic modeling. Modeling shows how P- and S-waves have a different time-lapse amplitude response with offset. The results from the laboratory experiments and modeling show the advantages of combining P- and S-wave attributes in recognizing the mechanism responsible for time-lapse changes due to CO2 injection
Revisiting Maximum Entropy Inverse Reinforcement Learning: New Perspectives and Algorithms
We provide new perspectives and inference algorithms for Maximum Entropy
(MaxEnt) Inverse Reinforcement Learning (IRL), which provides a principled
method to find a most non-committal reward function consistent with given
expert demonstrations, among many consistent reward functions.
We first present a generalized MaxEnt formulation based on minimizing a
KL-divergence instead of maximizing an entropy. This improves the previous
heuristic derivation of the MaxEnt IRL model (for stochastic MDPs), allows a
unified view of MaxEnt IRL and Relative Entropy IRL, and leads to a model-free
learning algorithm for the MaxEnt IRL model. Second, a careful review of
existing inference algorithms and implementations showed that they
approximately compute the marginals required for learning the model. We provide
examples to illustrate this, and present an efficient and exact inference
algorithm. Our algorithm can handle variable length demonstrations; in
addition, while a basic version takes time quadratic in the maximum
demonstration length L, an improved version of this algorithm reduces this to
linear using a padding trick.
Experiments show that our exact algorithm improves reward learning as
compared to the approximate ones. Furthermore, our algorithm scales up to a
large, real-world dataset involving driver behaviour forecasting. We provide an
optimized implementation compatible with the OpenAI Gym interface. Our new
insight and algorithms could possibly lead to further interest and exploration
of the original MaxEnt IRL model.Comment: Published as a conference paper at the 2020 IEEE Symposium Series on
Computational Intelligence (SSCI
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