Relaxation of Spin Polarized 3^3He in Mixtures of 3^3He and 4^4He Below the 4^4He Lambda Point

We report the first study of the depolarization behavior of spin polarized 3He in a mixture of 3He-4He at a temperature below the 4He Lambda point in a deuterated TetraPhenyl Butadiene-doped deuterated PolyStyrene (dTPB-dPS) coated acrylic cell. In our experiment the measured 3He relaxation time is due to the convolution of the 3He longitudinal relaxation time, T1, and the diffusion time constant of 3He in superfluid 4He since depolarization takes place on the walls. We have obtained a 3He relaxation time ~3000 seconds at a temperature around 1.9K. We have shown that it's possible to achieve values of wall depolarization probability on the order of (1-2)x10^-7 for polarized 3He in the superfluid 4He from a dTPB-dPS coated acrylic surface.Comment: The Model used to interpret the data has been change

日本とオーストラリアのダイエットに関する意識とその実態

わが国における飽食的食生活と文明の発達による便利な暮らしは、摂取エネルギーの増加と消費エネルギーの低下をもたらした。その結果、肥満に対する恐れと生活習慣病が助長され、人々の健康意識が向上し、現在、ダイエットが盛んに行われている。そこで、私たちは、健康寿命の長い国のベスト 5 に入りながら、生活習慣病が深刻な問題となっている日本とオーストラリアにおいてダイエットに関するアンケート調査を行い、両国におけるダイエットの現状を比較検討した。その結果、日本人の「人の目線を気にする」性格に対して、オーストラリアの人の「自分は自分」という性格の違いが、ダイエットの目的と実践に大きく影響をしていることや、日本では標準型が、オーストラリアでは肥満型がダイエットを行うなど、日本人は、肥満になる前にダイエットをするのに対し、オーストラリア人は、肥満になってからダイエットを行う傾向にあるなど、日本とオーストラリアのダイエットに対する意識の違いや方法が明らかになった。The eating habits of the gluttony in our country and the convenient living by the development of the civilization brought increase of the intake energy and the fall of the energy consumed.As a result, fear for the corpulence and a lifestyle-related disease were promoted. The health awareness of people improves, and a diet is performed.We belong under best 5 of a long country of the healthy life expectancy. However, a lifestyle-related disease becomes the serious problem. Therefore, I decided to perform questionary survey about the diet in Australia which had the problem that was similar to Japan. And I weighed the situation of the diet in the two countries

Epigenetic Chromatin Silencing: Bistability and Front Propagation

The role of post-translational modification of histones in eukaryotic gene regulation is well recognized. Epigenetic silencing of genes via heritable chromatin modifications plays a major role in cell fate specification in higher organisms. We formulate a coarse-grained model of chromatin silencing in yeast and study the conditions under which the system becomes bistable, allowing for different epigenetic states. We also study the dynamics of the boundary between the two locally stable states of chromatin: silenced and unsilenced. The model could be of use in guiding the discussion on chromatin silencing in general. In the context of silencing in budding yeast, it helps us understand the phenotype of various mutants, some of which may be non-trivial to see without the help of a mathematical model. One such example is a mutation that reduces the rate of background acetylation of particular histone side-chains that competes with the deacetylation by Sir2p. The resulting negative feedback due to a Sir protein depletion effect gives rise to interesting counter-intuitive consequences. Our mathematical analysis brings forth the different dynamical behaviors possible within the same molecular model and guides the formulation of more refined hypotheses that could be addressed experimentally.Comment: 19 pages, 5 figure

Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs

BACKGROUND: The canonical core promoter elements consist of the TATA box, initiator (Inr), downstream core promoter element (DPE), TFIIB recognition element (BRE) and the newly-discovered motif 10 element (MTE). The motifs for these core promoter elements are highly degenerate, which tends to lead to a high false discovery rate when attempting to detect them in promoter sequences. RESULTS: In this study, we have performed the first analysis of these core promoter elements in orthologous mouse and human promoters with experimentally-supported transcription start sites. We have identified these various elements using a combination of positional weight matrices (PWMs) and the degree of conservation of orthologous mouse and human sequences – a procedure that significantly reduces the false positive rate of motif discovery. Our analysis of 9,010 orthologous mouse-human promoter pairs revealed two combinations of three-way synergistic effects, TATA-Inr-MTE and BRE-Inr-MTE. The former has previously been putatively identified in human, but the latter represents a novel synergistic relationship. CONCLUSION: Our results demonstrate that DNA sequence conservation can greatly improve the identification of functional core promoter elements in the human genome. The data also underscores the importance of synergistic occurrence of two or more core promoter elements. Furthermore, the sequence data and results presented here can help build better computational models for predicting the transcription start sites in the promoter regions, which remains one of the most challenging problems

Modulation of NTC frequencies by Pc5 ULF pulsations : experimental test of the generation mechanism and magnetoseismology of the emitting surface

Nonthermal continuum (NTC) radiation is believed to be emitted by the conversion of an electrostatic wave into an electromagnetic one, which takes place at the Earth's magnetic equator. It is generally accepted that the frequency of the electrostatic wave at the source meets a local characteristic frequency placed in between two multiples of the electron cyclotron frequency, fce, which results in emission of a narrow band frequency element. In an event on 14 August 2003, we compare oscillations of the central frequency of distinct NTC frequency elements observed from Cluster orbiting near perigee, with simultaneous Pc5 Ultra Low Frequency (ULF) pulsations in the magnetic field observed from the same platform. The latter magnetic perturbations are interpreted as magnetohydrodynamic poloidal waves, where fundamental and second harmonic modes coexist. The NTC oscillation and the fundamental wave have similar periods, but are phase shifted by a quarter of period. From the correlation between both signals, and the proximity of the NTC source (localized via triangulation) with Cluster, we infer that the poloidal perturbations are spatially uniform between the source and the satellites. From the phase shift between signals, we conclude that the electrostatic wave which converts into NTC is mainly governed by the plasma density, affected by movements of the magnetic field lines. Furthermore, we demonstrate that the observations can be used to perform a magnetoseismology of the emitting surface. The results show a steepening of the plasmapause density profile near the satellites, which can be responsible for the generation of NTC emission

Transcription, one allele at a time

A recent study presents a technique allowing one to image transcription from a single gene copy in live cells, and highlights the dynamic nature of transcriptional regulation

Influence of Carbon Concentration on the Superconductivity in MgCxNi3

The influence of carbon concentration on the superconductivity (SC) in MgC$_{x}$Ni$_3$ has been investigated by measuring the low temperature specific heat combined with first principles electronic structure calculation. It is found that the specific heat coefficient $\gamma_n=C_{en}/T$ of the superconducting sample ($x\approx1$) in normal state is twice that of the non-superconducting one ($x\approx 0.85$). The comparison of measured $\gamma_n$ and the calculated electronic density of states (DOS) shows that the effective mass renormalization changes remarkably as the carbon concentration changes. The large mass renormalization for the superconducting sample and the low $T_{c}$(7K) indicate that more than one kind of boson mediated electron-electron interactions exist in MgC$_{x}$Ni$_3$.Comment: 4 pages, 4 figure