Thriving in a Changing Academic Landscape: Moving at the Speed of Light

Academic leaders are facing pressure to change how they deliver education. To respond, universities are increasingly charged with setting up educational programs that challenge the traditional notion of delivering classes. Using a case study approach, this session highlights how one university built a collaborative industry hub , developed interdisciplinary programs, and gained departmental and faculty buy-in in a sixth month window. Strategies for remaining nimble and transforming the ivory tower will discussed

86TH Annual Georgia Public Health Association Meeting & Conference Report

The 86th annual meeting of the Georgia Public Health Association (GPHA) and joint conference with the Southern Health Association was held in Atlanta, Georgia, on April 13-14, 2015, with pre-conference (April 12th) and post-conference (April14th) Executive Board meetings. As Georgia’s leading forum for public health researchers, practitioners, and students, the annual meeting of the GPHA brings together participants from across the state to explore recent developments in the field and to exchange techniques, tools, and experiences. Historically, the GPHA conference has been held in Savannah (n=24); Jekyll Island (n=20); Atlanta (n=16); Augusta (n=4); and Gainesville (n=1). There was no annual meeting during the early years (1929-1936); during World War II (1941-1943 and 1945); and for four years during the 1980s. Between 2006 and 2010, GPHA held one-day annual meetings and business sessions with educational workshops. Several new initiatives were highlighted as part of this year’s conference. These included a “move and groove” physical activity lounge, registration scholarships for students with a dedicated meet-and-greet reception, an expanded exhibit hall, presentation and approval of three resolutions (related to healthy foods at official activities and events; weapons at official activities and events; and memorials), and approval of the 2015 legislative policy positions and amended association bylaws. The theme for the conference was Advocacy in Action for Public Health. Specifically, the program addressed ensuring access to care; protecting funding for core programs, services, and infrastructure; eliminating health disparities; and addressing key public health issues important to the state of Georgia. One hundred and nine (109) abstracts were submitted for peer review; 36 were accepted for poster and 40 for workshop presentations. Four plenary sessions with keynote speakers covered the intersection between advocacy and policy, Georgia’s response to the Ebola crisis, palliative care, and essentials of advocacy in action for public health. Concurrent workshops focused on Board of Health training, public health accreditation, capacity building, collaboration, patient-centered outcomes, synthetic cannabinoid use, the HIV care continuum, use of data for informed decision making, environmental threats, organizational development, epidemiology, policy, and regulation. Thirty-two (32) awards were presented, including Lawmaker of the Year Award to Governor Nathan and First Lady Sandra Deal for their active and engaged role in promoting public health in Georgia; and the Sellers-McCroan Award to Commissioner Brenda Fitzgerald, Georgia Department of Public Health (DPH) State Health Officer, for her leadership of the Georgia Ebola Response Team and leadership of the newly formed department. The conference attracted 569 registrants primarily through pre-registration (n=561) with limited onsite registration (n=8). For this year’s conference, there was a significant increase in attendance (36%) and exhibitors (33%) relative to 2014. Of registrants reporting GPHA section participation, representation included: academic (5%); administration (10%); boards of health (13%); career development (15%); emergency preparedness (2%); epidemiology (5%); health education and promotion (2%); information technology (2%); maternal and child health (3%); medical/dental (3%); nursing (10%); nutrition

88th Annual Georgia Public Health Association Meeting & Conference Report

The 88th Annual Meeting of the Georgia Public Health Association (GPHA) was held in Atlanta, Georgia, on April 11-12, 2017, with pre-conference (April 10th) and post-conference (April 12th) Executive Board meetings. As Georgia’s leading forum for public health researchers, practitioners, and students, the annual meeting of the GPHA brings together participants from across the state to explore recent developments in the field and to exchange techniques, tools, and experiences. In recent years the venue for the GPHA annual conference has been Atlanta, but in an effort to expand participation across the state the 2018 GPHA Annual Meeting and Conference is scheduled to be held on Jekyll Island, GA (April 4-6. 2018). This conference built on the successes of the previous years’ conferences. These included the continuation of offering three pre-conference workshops, an expansion of sponsorships, more poster sessions, more CEU-certified workshops, and the expansion of dedicated tracks for administration, accreditation, and boards of health training. The theme for the 2017 conference was People, Providers, Professionals, and Partners, which reflects an understanding of the all-encompassing nature of who is part of public health in Georgia. Public Health in Georgia includes all individuals who live, work, and play in Georgia, not just those who provide public health services through government agencies. It includes those in education, public safety, and emergency services. It includes those in private industry as well as public. It includes those working for foundations, non-profit, and non-governmental organizations who are working for the health of all Georgians. All of these individuals have a role in Georgia’s public health, and, therefore, a reason to be at the GPHA annual conference. One hundred and thirty-three (133) abstracts were submitted for peer review; 52 were accepted for poster (41 by students) and 62 for workshop presentations. Four plenary sessions with keynote speakers covered the international, national, and local response to the Zika pandemic, and setting the stage for further discussions on the future workforce education and training challenges for public health in Georgia. Concurrent workshops focused on board of health training, public health accreditation, genomics, environmental health regulations, continuing education of nurses, best practices learned from natural disasters, community capacity building, and lessons learned from other surveillance activities in dealing with the emerging Zika disease crisis, and the implementation of policies and regulations. Seventeen (17) GPHA awards were presented at the conference, including Legislator of the Year Award to State Senator Renee Untermann (a two-time award winner) for her legislative efforts critical to the success of public health initiatives in Georgia. These efforts included working tirelessly to keep the Department of Public Health funded and increase “hold harmless” funding for county boards of health, push through funding to make public health nursing salaries competitive, and a host of other issues. The Sellers-McCroan Award went to the Gwinnett, Newton, and Rockdale Health District Epidemiology Team (Brittany Carter, MPH; Catherine Clark, RN, MPH, CIC; and Modu Feyistitan, MPH) for their tieless work in keeping the people of their health district safe. The Gwinnett, Newton, and Rockdale Epidemiology Team has consistently investigated more outbreaks than any other health district and has excelled in their targeted approaches to education and disease control. The conference attracted 534 registrants (491 one- or two-day attendees, 26 luncheon-only, and 10 President’s Reception only). This was a 12.4% increase over the previous year. Additionally, there was a 55% increase in the number of workshops offered (n=62), and a 15.6% increase in the number of poster presentations (n=52). The number of exhibitors decreased by 13.9% (n=31), but the number of sponsors increased, by 46.7% (n=22) compared to 2016. Conference sponsorships brought in $82,850, a 14.1$85,000. Of registrants reporting GPHA section participation, representation included: Academic (6.4%); Administration (15.7%); Behavioral Health (0.3%); Boards of Health (9.3%); Career Development (6.1%); Safety and Health Preparedness (0.3%); Environmental Health (5.5%); Epidemiology (7.4%); Health Education and Promotion (15.7%); Information Technology (2.2%); Maternal and Child Health (5.5%); Medical/Dental (2.2%); Nursing (13.8%); Nutrition (8.0%); and Primary Care (0.6%). Yvette Daniels, JD, of the Department of Public Health was instrumental in working to revitalize the Nutrition Section participation at the Annual Meeting and Conference. There was 100% participation in the conference from the state’s 18 public health districts again this year. The online conference evaluation completed by a representative sample of registrants indicated areas of potential improvement as: include all speakers in handbook, handouts available, diversity in concurrent sessions, better scheduling of poster sessions, use of technology and social media for changes in programming and locations, avoid Holy Week and/or Passover, conference date earlier in calendar year or during summer would bring more county-level participation. Over 90 percent rated the conference as “good” or “excellent.

87th Annual Georgia Public Health Association Meeting & Conference Report

The 87th Annual Meeting of the Georgia Public Health Association (GPHA) was held in Atlanta, Georgia, on March 22-23, 2016, with pre-conference (March 21st) and post-conference (March 23rd) Executive Board meetings. As Georgia’s leading forum for public health researchers, practitioners, and students, the annual meeting of the GPHA brings together participants from across the state to explore recent developments in the field and to exchange techniques, tools, and experiences. In recent years the venue for the GPHA annual conference has been Atlanta, with the 2017 GPHA Annual Meeting and Conference also scheduled to be held in Atlanta. Several new initiatives were highlighted as part of this year’s conference. These included three pre-conference workshops, expansion of academic sponsorships, an enhanced exhibit hall integrated with the poster sessions, silent auction, breaks and President’s Reception, an information booth, and an inaugural administration section track. The 2016 Annual Meeting & Conference added the Certified in Public Health (CPH) Continuing Education (CE) designation. The theme for the conference was Understanding Public Health: Research, Evidence and Practice, which reflects the science of public health

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two

Background The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd. Methods We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background. Results First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001). Conclusions In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival

Disrupting Race, Claiming Colonization: Collective Remembering and Rhetorical Colonialism in Negotiating (Native) American Identities in the U.S.

This critical rhetorical critique interrogates rhetorics of memory in negotiations of national identity, especially as they address race and colonialism. We need to rethink race in more complex ways that disrupt homogenous conceptions of who belongs in the U.S., instead embracing the possibilities offered in those liminal spaces of racial national identities, such as (Native)American. Doing so requires acknowledging the reverberations of past rhetorics in contemporary sense-making and how those echoes vary across communities. In exploring how we (mis)remember race and colonization in relation to nation, my concern lies in exposing some of the persistent rhetorical strategies that impede social justice efforts by marginalized communities, as well as the resistive rhetorics these communities respond with. Pursuing this project, I rely on investigating rhetorical mnemonic strategies of race, nation, and colonialism in everyday discourses about the relationship(s) between a Euro-American community in Lawrence, Kansas and a pan-Indian community associated with Haskell Indian Nations University (HINU) to reveal how we negotiate national identities in relation to the past and to one another. At its core, this ideological critique of rhetorics of race, nation, memory and colonialism is an investigation of identity negotiation among two representative communities in disparate positions of power, their places constituted across several centuries of racist discourses that we too-often continue to rely on. In examining historic Assimilation Era discourses from Haskell Indian Boarding School as well as recent discourses produced by the Lawrence, Kansas, and HINU communities about a local land controversy, I interrogate the role of memory in contemporary negotiations of identity and reveal ways the normative assumptions of U.S. citizenship are profoundly raced. I also propose the idea of “enabling uncertainty” as a perspective that explicitly troubles narrow and limiting conceptions of racial identities, highlighting the idea through discussion of the complex ways (Native)Americans navigate the interstices between Native and American identities

Disrupting race, claiming colonization: Collective remembering and rhetorical colonization in negotiating (Native)American identities in the U.S..

This critical rhetorical critique interrogates rhetorics of memory in negotiations of national identity, especially as they address race and colonialism. We need to rethink race in more complex ways that disrupt homogenous conceptions of who belongs in the U.S., instead embracing the possibilities offered in those liminal spaces of racial national identities, such as (Native)American. Doing so requires acknowledging the reverberations of past rhetorics in contemporary sense-making and how those echoes vary across communities. In exploring how we (mis)remember race and colonization in relation to nation, my concern lies in exposing some of the persistent rhetorical strategies that impede social justice efforts by marginalized communities, as well as the resistive rhetorics these communities respond with. Pursuing this project, I rely on investigating rhetorical mnemonic strategies of race, nation, and colonialism in everyday discourses about the relationship(s) between a Euro-American community in Lawrence, Kansas and a pan-Indian community associated with Haskell Indian Nations University (HINU) to reveal how we negotiate national identities in relation to the past and to one another. At its core, this ideological critique of rhetorics of race, nation, memory and colonialism is an investigation of identity negotiation among two representative communities in disparate positions of power, their places constituted across several centuries of racist discourses that we too-often continue to rely on. In examining historic Assimilation Era discourses from Haskell Indian Boarding School as well as recent discourses produced by the Lawrence, Kansas, and HINU communities about a local land controversy, I interrogate the role of memory in contemporary negotiations of identity and reveal ways the normative assumptions of U.S. citizenship are profoundly raced. I also propose the idea of “enabling uncertainty” as a perspective that explicitly troubles narrow and limiting conceptions of racial identities, highlighting the idea through discussion of the complex ways (Native)Americans navigate the interstices between Native and American identities

OHS Oral Histories

Interview with Barney Christy, one taking place on March.3,1983 and 1985, discussing his life experiences