993 research outputs found

    Kondo Quantum Dots and the Novel Kondo-doublet interaction

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    We analyze the interactions between two Kondo Quantum Dots connected to a Rashba-active Quantum Wire. We find that the Kondo-doublet interaction, at an inter-dot distance of the order of the wire Fermi length, is over an order of magnitude greater than the RKKY interaction. The effects induced on the Kondo-doublet interaction by the wire spin-orbit coupling can be used to control the Quantum Dots spin-spin correlation. These results imply that the widely used assumption that the RKKY is the dominant interaction between Anderson impurities must be revised.Comment: 4 pages, 4 figs, accepted for publication in PRL. title changed and text polishe

    Simulation of a particle-laden turbulent channel flow using an improved stochastic Lagrangian model

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    The purpose of this paper is to examine the Lagrangian stochastic modeling of the fluid velocity seen by inertial particles in a nonhomogeneous turbulent flow. A new Langevin-type model, compatible with the transport equation of the drift velocity in the limits of low and high particle inertia, is derived. It is also shown that some previously proposed stochastic models are not compatible with this transport equation in the limit of high particle inertia. The drift and diffusion parameters of these stochastic differential equations are then estimated using direct numerical simulation (DNS) data. It is observed that, contrary to the conventional modeling, they are highly space dependent and anisotropic. To investigate the performance of the present stochastic model, a comparison is made with DNS data as well as with two different stochastic models. A good prediction of the first and second order statistical moments of the particle and fluid seen velocities is obtained with the three models considered. Even for some components of the triple particle velocity correlations, an acceptable accordance is noticed. The performance of the three different models mainly diverges for the particle concentration and the drift velocity. The proposed model is seen to be the only one which succeeds in predicting the good evolution of these latter statistical quantities for the range of particle inertia studied

    Coulomb interaction effects on the electronic structure of radial polarized excitons in nanorings

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    The electronic structure of radially polarized excitons in structured nanorings is analyzed, with emphasis in the ground-state properties and their dependence under applied magnetic fields perpendicular to the ring plane. The electron-hole Coulomb attraction has been treated rigorously, through numerical diagonalization of the full exciton Hamiltonian in the non-interacting electron-hole pairs basis. Depending on the relative weight of the kinetic energy and Coulomb contributions, the ground-state of polarized excitons has "extended" or "localized" features. In the first case, corresponding to small rings dominated by the kinetic energy, the ground-state shows Aharonov-Bohm (AB) oscillations due to the individual orbits of the building particles of the exciton. In the localized regime, corresponding to large rings dominated by the Coulomb interaction, the only remaining AB oscillations are due to the magnetic flux trapped between the electron and hole orbits. This dependence of the exciton, a neutral excitation, on the flux difference confirms this feature as a signature of Coulomb dominated polarized excitons. Analytical approximations are provided in both regimens, which accurate reproduce the numerical results.Comment: 9 pages, including 6 figure

    Forensic identification of urine samples: a comparison between nuclear and mitochondrial DNA markers

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    Urine samples from 20 male volunteers of European Caucasian origin were stored at 4°C over a 4-month period in order to compare the identification potential of nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) markers. The amount of nDNA recovered from urines dramatically declined over time. Consequently, nDNA likelihood ratios (LRs) greater than 1,000 were obtained for 100, 70 and 55% of the urines analysed after 6, 60 and 120 days, respectively. For the mtDNA, HVI and HVII sequences were obtained for all samples tested, whatever the period considered. Nevertheless, the highest mtDNA LR of 435 was relatively low compared to its nDNA equivalent. Indeed, LRs obtained with only three nDNA loci could easily exceed this value and are quite easier to obtain. Overall, the joint use of nDNA and mtDNA markers enabled the 20 urine samples to be identified, even after the 4-month perio

    Combined Bacteriophage and Antibiotic Treatment Prevents Pseudomonas aeruginosa Infection of Wild Type and cftr- Epithelial Cells.

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    With the increase of infections due to multidrug resistant bacterial pathogens and the shortage of antimicrobial molecules with novel targets, interest in bacteriophages as a therapeutic option has regained much attraction. Before the launch of future clinical trials, in vitro studies are required to better evaluate the efficacies and potential pitfalls of such therapies. Here we studied in an ex vivo human airway epithelial cell line model the efficacy of phage and ciprofloxacin alone and in combination to treat infection by Pseudomonas aeruginosa. The Calu-3 cell line and the isogenic CFTR knock down cell line (cftr-) infected apically with P. aeruginosa strain PAO1 showed a progressive reduction in transepithelial resistance during 24 h. Administration at 6 h p.i. of single phage, phage cocktails or ciprofloxacin alone prevented epithelial layer destruction at 24 h p.i. Bacterial regrowth, due to phage resistant mutants harboring mutations in LPS synthesis genes, occurred thereafter both in vitro and ex vivo. However, co-administration of two phages combined with ciprofloxacin efficiently prevented PAO1 regrowth and maintained epithelial cell integrity at 72 p.i. The phage/ciprofloxacin treatment did not induce an inflammatory response in the tested cell lines as determined by nanoString <sup>®</sup> gene expression analysis. We conclude that combination of phage and ciprofloxacin efficiently protects wild type and cftr- epithelial cells from infection by P. aeruginosa and emergence of phage resistant mutants without inducing an inflammatory response. Hence, phage-antibiotic combination should be a safe and promising anti-Pseudomonas therapy for future clinical trials potentially including cystic fibrosis patients

    Current-voltage characteristics of diluted Josephson-junction arrays: scaling behavior at current and percolation threshold

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    Dynamical simulations and scaling arguments are used to study the current-voltage (IV) characteristics of a two-dimensional model of resistively shunted Josephson-junction arrays in presence of percolative disorder, at zero external field. Two different limits of the Josephson-coupling concentration pp are considered, where pcp_c is the percolation threshold. For pp >> pcp_c and zero temperature, the IV curves show power-law behavior above a disorder dependent critical current. The power-law behavior and critical exponents are consistent with a simple scaling analysis. At pcp_c and finite temperature TT, the results show the scaling behavior of a T=0 superconducting transition. The resistance is linear but vanishes for decreasing TT with an apparent exponential behavior. Crossover to non-linearity appears at currents proportional to % T^{1+\nu_T}, with a thermal-correlation length exponent νT\nu_T consistent with the corresponding value for the diluted XY model at pcp_c.Comment: Revtex, 9 postscript pages, to appear in Phys. Rev.

    Liquid/Liquid Extraction Kinetics of Eu(III) and Am(III) by Extractants Designed for the Industrial Reprocessing of Nuclear Wastes

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    Results about the kinetics of extraction of Eu(III) and Am(III) by extractants designed for the industrial reprocessing of nuclear wastes are reported. They were obtained using the rotating membrane cell (RMC) technique. Extraction and stripping kinetic rate constants were determined for various compositions of the aqueous and organic phases. The transfer was studied at liquid/liquid interfaces between an aqueous nitric acid solution and an organic solvent containing the diglycolamide extractant molecule N,N,N′,N′-tetra-n-octyl-diglycolamide (TODGA) or a mixture of the bipyridine molecule CyMe4BTBP with TODGA (the latter being used as a phase-transfer catalyst), dissolved in an aliphatic diluent. In some experiments, an aqueous ligand (a sulfonated bis triazinyl pyridine, SO3-Ph-BTP, or a PyTri-diol) was added to the aqueous phase as a stripping agent. The diffusion coefficients of Eu(III) and Am(III), which are key in the analysis of the kinetic data, were measured using the RMC and the closed capillary technique. Whenever possible, mechanisms are proposed to interpret the experimental results
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