A hexahomotrioxacalix[3]arene-based ditopic receptor for alkylammonium ions controlled by Ag + ions 4

A receptor cone-1 based on a hexahomotrioxacalix[3]arene bearing three pyridyl groups 21 was successfully synthesized, which has a C3-symmetric conformation and is capable of binding 22 alkylammonium and metal ions simultaneously in a cooperative fashion. It can bind 23 alkylammonium ions through the -cavity formed by three aryl rings. This behaviour is consistent 24 with the cone-in/cone-out conformational rearrangement needed to reorganize the cavity for 25 endo-complexation. As a C3-symmetrical pyridyl-substituted calixarene, receptor cone-1 can also 26 bind a Ag + ion and the nitrogen atoms are turned towards the inside of the cavity and interact with 27 Ag +. After complexation of tris(2-pyridylamide) derivative receptor cone-1 with Ag + , the original 28 C3-symmetry was retained and higher complexation selectivity for n-BuNH3 + versus t-BuNH3 + was 29 observed. Thus, it is believed that this receptor will have a role to play in the sensing, detection, and 30 recognition of Ag + and n-BuNH3 + ions. 3

Nanoelectromechanical relay without pull-in instability for high-temperature non-volatile memory

Emerging applications such as the Internet-of-Things and more-electric aircraft require electronics with integrated data storage that can operate in extreme temperatures with high energy efficiency. As transistor leakage current increases with temperature, nanoelectromechanical relays have emerged as a promising alternative. However, a reliable and scalable non-volatile relay that retains its state when powered off has not been demonstrated. Part of the challenge is electromechanical pull-in instability, causing the beam to snap in after traversing a section of the airgap. Here we demonstrate an electrostatically actuated nanoelectromechanical relay that eliminates electromechanical pull-in instability without restricting the dynamic range of motion. It has several advantages over conventional electrostatic relays, including low actuation voltages without extreme reduction in critical dimensions and near constant actuation airgap while the device moves, for improved electrostatic control. With this nanoelectromechanical relay we demonstrate the first high-temperature non-volatile relay operation, with over 40 non-volatile cycles at 200 ∘C

EVH Black Holes, AdS3 Throats and EVH/CFT Proposal

Within class of generic black holes there are extremal black holes (with vanishing Hawking temperature T) and vanishing horizon area Ah, but with finite Ah/T ratio,the Extremal Vanishing Horizon (EVH) black holes. We study the near horizon limit of a four dimensional EVH black hole solution to a generic (gauged) Einstein-Maxwell dilaton theory and show that in the near horizon limit they develop a throat which is a pinching orbifold limit of AdS3. This is an extension of the well known result for extremal black holes the near horizon limit of which contains an AdS2 throat. We show that in the near EVH near horizon limit the pinching AdS3 factor turns to a pinching BTZ black hole and that this near horizon limit is indeed a decoupling limit. We argue that the pinching AdS3 or BTZ orbifold is resolved if the near horizon limit is accompanied by taking the 4d Newton constant G4 to zero such that the Bekenstein-Hawking entropy S = Ah/(4G4) remains finite. We propose that in this limit the near horizon EVH black hole is dual to a 2d CFT. We provide pieces of evidence in support of the EVH/CFT correspondence and comment on its connection to the Kerr/CFT proposal and speculations how the EVH/CFT may be used to study generic e.g. Schwarzchild-type black holes.Comment: 31 pages, 3 figures, JHEP styl

Predicting consumer product demands via Big Data: the roles of online promotional marketing and online reviews

This study aims to investigate the contributions of online promotional marketing and online reviews as predictors of consumer product demands. Using electronic data from Amazon.com, we attempt to predict if online review variables such as valence and volume of reviews, the number of positive and negative reviews, and online promotional marketing variables such as discounts and free deliveries, can influence the demand of electronic products in Amazon.com. A Big Data architecture was developed and Node.JS agents were deployed for scraping the Amazon.com pages using asynchronous Input/Output calls. The completed Web crawling and scraping data-sets were then preprocessed for Neural Network analysis. Our results showed that variables from both online reviews and promotional marketing strategies are important predictors of product demands. Variables in online reviews in general were better predictors as compared to online marketing promotional variables. This study provides important implications for practitioners as they can better understand how online reviews and online promotional marketing can influence product demands. Our empirical contributions include the design of a Big Data architecture that incorporate Neural Network analysis which can used as a platform for future researchers to investigate how Big Data can be used to understand and predict online consumer product demands

Current continuing professional education practice among Malaysian nurses

Nurses need to participate in CPE to update their knowledge and increase their competencies. This research was carried out to explore their current practice and the future general needs for CPE. This cross-sectional descriptive study involved registered nurses from government hospitals and health clinics from Peninsular Malaysia. Multistage cluster sampling was used to recruit 1000 nurses from four states of Malaysia. Self-explanatory questionnaires were used to collect the data, which were analyzed using SPSS version 16. Seven hundred and ninety-two nurses participated in this survey. Only 80% (562) of the nurses had engaged in CPE activities during the past 12 months. All attendance for the various activities was below 50%. Workshops were the most popular CPE activity (345, 43.6%) and tertiary education was the most unpopular activity (10, 1.3%). The respondents did perceive the importance of future CPE activities for career development. Mandatory continuing professional education (MCPE) is a key measure to ensure that nurses upgrade their knowledge and skills; however, it is recommended that policy makers and nurse leaders in the continuing professional development unit of health service facilities plan CPE activities to meet registered nurses’ (RNs) needs and not simply organizational requirements

The CJIE1 prophage of Campylobacter jejuni affects protein expression in growth media with and without bile salts

BACKGROUND: The presence of Campylobacter jejuni temperate bacteriophages has increasingly been associated with specific biological effects. It has recently been demonstrated that the presence of the prophage CJIE1 is associated with increased adherence and invasion of C. jejuni isolates in cell culture assays. RESULTS: Quantitative comparative proteomics experiments were undertaken using three closely related isolates with CJIE1 and one isolate without CJIE1 to determine whether there was a corresponding difference in protein expression levels. Initial experiments indicated that about 2% of the total proteins characterized were expressed at different levels in isolates with or without the prophage. Some of these proteins regulated by the presence of CJIE1 were associated with virulence or regulatory functions. Additional experiments were conducted using C. jejuni isolates with and without CJIE1 grown on four different media: Mueller Hinton (MH) media containing blood; MH media containing 0.1% sodium deoxycholate, which is thought to result in increased expression of virulence proteins; MH media containing 2.5% Oxgall; and MHwithout additives. These experiments provided further evidence that CJIE1 affected protein expression, including virulence-associated proteins. They also demonstrated a general bile response involving a majority of the proteome and clearly showed the induction of almost all proteins known to be involved with iron acquisition. The data have been deposited to the ProteomeXchange with identifiers PXD000798, PXD000799, PXD000800, and PXD000801. CONCLUSION: The presence of the CJIE1 prophage was associated with differences in protein expression levels under different conditions. Further work is required to determine what genes are involved in causing this phenomenon

Multiple photoluminescence from pyrene-fused hexaarylbenzenes with aggregation-enhanced emission features

© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Multiple photoluminescence, which included monomer emission, excimer emission, and charge-transfer emission processes, has been observed from new pyrene-fused hexaarylbenzene (HAB) compounds, which were synthesized in high yields through a Diels–Alder reaction between bis(2-tert-butylpyren-6-yl)acetylene and tetraphenylcyclopentadienone. Although the differentiation between the two molecules only arose from the geometrical position of one of the pyrenes, the NMR spectra, crystal packing, and physicochemical properties of these pyrene-based HAB hybrids were distinctly different in both the solution and aggregate states. X-ray diffraction analysis clearly indicated that the pyrene moieties adopted different crystal packing arrangements in the crystalline state that could induce a multiple-photoluminescence phenomenon

A soliton menagerie in AdS

We explore the behaviour of charged scalar solitons in asymptotically global AdS4 spacetimes. This is motivated in part by attempting to identify under what circumstances such objects can become large relative to the AdS length scale. We demonstrate that such solitons generically do get large and in fact in the planar limit smoothly connect up with the zero temperature limit of planar scalar hair black holes. In particular, for given Lagrangian parameters we encounter multiple branches of solitons: some which are perturbatively connected to the AdS vacuum and surprisingly, some which are not. We explore the phase space of solutions by tuning the charge of the scalar field and changing scalar boundary conditions at AdS asymptopia, finding intriguing critical behaviour as a function of these parameters. We demonstrate these features not only for phenomenologically motivated gravitational Abelian-Higgs models, but also for models that can be consistently embedded into eleven dimensional supergravity.Comment: 62 pages, 21 figures. v2: added refs and comments and updated appendice

Probing many-body noise in a strongly interacting two-dimensional dipolar spin system

The most direct approach for characterizing the quantum dynamics of a strongly-interacting system is to measure the time-evolution of its full many-body state. Despite the conceptual simplicity of this approach, it quickly becomes intractable as the system size grows. An alternate framework is to think of the many-body dynamics as generating noise, which can be measured by the decoherence of a probe qubit. Our work centers on the following question: What can the decoherence dynamics of such a probe tell us about the many-body system? In particular, we utilize optically addressable probe spins to experimentally characterize both static and dynamical properties of strongly-interacting magnetic dipoles. Our experimental platform consists of two types of spin defects in diamond: nitrogen-vacancy (NV) color centers (probe spins) and substitutional nitrogen impurities (many-body system). We demonstrate that signatures of the many-body system's dimensionality, dynamics, and disorder are naturally encoded in the functional form of the NV's decoherence profile. Leveraging these insights, we directly characterize the two-dimensional nature of a nitrogen delta-doped diamond sample. In addition, we explore two distinct facets of the many-body dynamics: First, we address a persistent debate about the microscopic nature of spin dynamics in strongly-interacting dipolar systems. Second, we demonstrate direct control over the spectral properties of the many-body system, including its correlation time. Our work opens the door to new directions in both quantum sensing and simulation.Comment: 10 + 8 + 5 pages; 3 + 5 figure