237 research outputs found
anomalies and simplified limits on models at the LHC
The LHCb collaboration has recently reported a 2.5 discrepancy with
respect to the predicted value in a test of lepton universality in the ratio
.
Coupled with an earlier observation of a similar anomaly in , this has
generated significant excitement. A number of new physics scenarios have been
proposed to explain the anomaly. In this work we consider simplified limits on
models from ATLAS and CMS searches for new resonances in dilepton and
dijet modes, and we use the simplified limits variable to correlate the
results of the resonance and B-decay experiments. By examining minimal
models that can accomodate the observed LHCb results, we show that the
high-mass resonance search results are begining to be sensitive to these models
and that future results will be more informative.Comment: 24 pages, 5 figures. Typo corrected, resulting in strengthened
limits. Additional references added; minor corrections found in referee
process include
Expressive Aphasia and Carotid Dissection
Ultrasound images of a patient presenting to the emergency department with expressive aphasia who was found to have carotid dissection. The first image is a standard two dimensional image that depicts the internal carotid with a visible flap within the lumen. The second image is a color Doppler image showing turbulent flow within the true lumen and visible flow within the false lumen. The case and the patient’s outcome are summarized along with some teaching points about carotid dissection. Also, there is some background and research on using ultrasound to help identify dissection
Aerospike Rockets for Increased Space Launch Capability
The US Department of Defense DOD increasingly depends on space assets for everyday operations. Precision navigation communications and intelligence, surveillance, and reconnaissance satellites are highly leveraged space assets. The launch vehicles that place these satellites in orbit are a major limitation of current space systems. If higher-performing launch vehicles were available, many satellites could accommodate additional capabilities, whether in terms of more sensor channels, types of payloads, electrical power, or propellant for orbital maneuvering and station keeping. Space assets are typically designed to conform to a particular launch vehicle s limitations e.g., engineers might design a satellite to be carried by a Delta IV-2 medium launch vehicle. Essentially, this choice of vehicle fixes the maximum mass of the satellite and, thus, its capabilities. If a launcher capable of placing more mass in the desired orbit were available at similar cost, the satellite s design could allow for additional capability. Furthermore, some payloads are too heavy for present-day launch vehicles to place into a particular orbit. A better-performing launcher would enable us to put those payloads into the desired orbits, permitting new missions and capabilities
Scattering Amplitudes of Massive Spin-2 Kaluza-Klein States with Matter
We perform a comprehensive analysis of the scattering of matter and
gravitational Kaluza-Klein (KK) modes in five-dimensional gravity theories. We
consider matter localized on a brane as well as in the bulk of the extra
dimension for scalars, fermions and vectors respectively, and consider an
arbitrary warped background. While naive power-counting suggests that there are
amplitudes which grow as fast as [where is the
center-of-mass scattering energy-squared], we demonstrate that cancellations
between the various contributions result in a total amplitude which grows no
faster than . Extending previous work on the self-interactions of
the gravitational KK modes, we show that these cancellations occur due to
sum-rule relations between the couplings and the masses of the modes that can
be proven from the properties of the mode equations describing the gravity and
matter wavefunctions. We demonstrate that these properties are tied to the
underlying diffeomorphism invariance of the five-dimensional theory. We discuss
how our results generalize when the size of the extra dimension is stabilized
via the Goldberger-Wise mechanism. Our conclusions are of particular relevance
for freeze-out and freeze-in relic abundance calculations for dark matter
models including a spin-2 portal arising from an underlying five-dimensional
theory.Comment: 34 pages, 3 figures. Footnote added on page
Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses
Introduction: The rising global burden of metabolic disease impacts the control of endemic tuberculosis (TB) in many regions, as persons with diabetes mellitus (DM) are up to three times more likely to develop active TB than those without DM. Active TB can also promote glucose intolerance during both acute infection and over a longer term, potentially driven by aspects of the immune response. Identifying patients likely to have persistent hyperglycemia following TB treatment would enable closer monitoring and care, and an improved understanding of underlying immunometabolic dysregulation.
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Methods: We measured the relationship of plasma cytokine levels, T cell phenotypes and functional responses with the change in hemoglobin A1c (HbA1c) before and after treatment of pulmonary TB in a prospective observational cohort in Durban, South Africa. Participants were stratified based on stable/increased HbA1c (n = 16) versus decreased HbA1c (n = 46) levels from treatment initiation to 12 month follow-up.
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Results: CD62 P-selectin was up- (1.5-fold) and IL-10 downregulated (0.85-fold) in plasma among individuals whose HbA1c remained stable/increased during TB treatment. This was accompanied by increased pro-inflammatory TB-specific IL-17 production (Th17). In addition, Th1 responses were upregulated in this group, including TNF-α production and CX3CR1 expression, with decreased IL-4 and IL-13 production. Finally, the TNF-α+ IFNγ+ CD8+ T cells were associated with stable/increased HbA1c. These changes were all significantly different in the stable/increased HbA1c relative to the decreased HbA1c group.
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Discussion: Overall, these data suggest that patients with stable/increased HbA1c had an increased pro-inflammatory state. Persistent inflammation and elevated T cell activity in individuals with unresolved dysglycemia following TB treatment may indicate failure to fully resolve infection or may promote persistent dysglycemia in these individuals, and further studies are needed to explore potential mechanisms
Dynamic nuclear polarization and nuclear magnetic resonance in the vicinity of edge states of a 2DES in GaAs quantum wells
Abstract Nuclear magnetic resonance is detected via the in-plane conductivity of a two-dimensional electron system at unity Landau level filling factor in the regime of the quantum Hall effect in narrow and wide quantum wells. The NMR is spatially selective to nuclei with a coupling to electrons in the current carrying edge states at the perimeter of the 2DES. Interpretation of the electron-nuclear double resonance signals is facilitated by numerical simulations. A new RF swept method for conductivity-detected NMR is introduced which offers more efficient signal averaging. The method is applied to the study of electric quadrupole interactions, weakly allowed overtone transitions, and evaluation of the extent of electron wave function delocalization in the wide quantum well. r 2005 Published by Elsevier Inc
The most luminous, merger-free AGN show only marginal correlation with bar presence
The role of large-scale bars in the fuelling of active galactic nuclei (AGN)
is still debated, even as evidence mounts that black hole growth in the absence
of galaxy mergers cumulatively dominated and may substantially influence disc
(i.e., merger-free) galaxy evolution. We investigate whether large-scale
galactic bars are a good candidate for merger-free AGN fuelling. Specifically,
we combine slit spectroscopy and Hubble Space Telescope imagery to characterise
star formation rates (SFRs) and stellar masses of the unambiguously
disc-dominated host galaxies of a sample of luminous, Type-1 AGN with 0.02 < z
0.024. After carefully correcting for AGN signal, we find no clear difference
in SFR between AGN hosts and a stellar mass-matched sample of galaxies lacking
an AGN (0.013 < z < 0.19), although this could be due to a small sample size
(n_AGN = 34). We correct for SFR and stellar mass to minimise selection biases,
and compare the bar fraction in the two samples. We find that AGN are
marginally (1.7) more likely to host a bar than inactive galaxies, with
AGN hosts having a bar fraction, fbar = 0.59^{+0.08}_{-0.09} and inactive
galaxies having a bar fraction fbar = 0.44^{+0.08}_{-0.09}. However, we find no
further differences between SFR- and mass-matched AGN and inactive samples.
While bars could potentially trigger AGN activity, they appear to have no
further, unique effect on a galaxy's stellar mass or SFR.Comment: 15 pages (9 figures). Accepted for publication in MNRA
A Cautionary Tale: MARVELS Brown Dwarf Candidate Reveals Itself To Be A Very Long Period, Highly Eccentric Spectroscopic Stellar Binary
We report the discovery of a highly eccentric, double-lined spectroscopic
binary star system (TYC 3010-1494-1), comprising two solar-type stars that we
had initially identified as a single star with a brown dwarf companion. At the
moderate resolving power of the MARVELS spectrograph and the spectrographs used
for subsequent radial-velocity (RV) measurements (R ~ <30,000), this particular
stellar binary mimics a single-lined binary with an RV signal that would be
induced by a brown dwarf companion (Msin(i)~50 M_Jup) to a solar-type primary.
At least three properties of this system allow it to masquerade as a single
star with a very low-mass companion: its large eccentricity (e~0.8), its
relatively long period (P~238 days), and the approximately perpendicular
orientation of the semi-major axis with respect to the line of sight (omega~189
degrees). As a result of these properties, for ~95% of the orbit the two sets
of stellar spectral lines are completely blended, and the RV measurements based
on centroiding on the apparently single-lined spectrum is very well fit by an
orbit solution indicative of a brown dwarf companion on a more circular orbit
(e~0.3). Only during the ~5% of the orbit near periastron passage does the
true, double-lined nature and large RV amplitude of ~15 km/s reveal itself. The
discovery of this binary system is an important lesson for RV surveys searching
for substellar companions; at a given resolution and observing cadence, a
survey will be susceptible to these kinds of astrophysical false positives for
a range of orbital parameters. Finally, for surveys like MARVELS that lack the
resolution for a useful line bisector analysis, it is imperative to monitor the
peak of the cross-correlation function for suspicious changes in width or
shape, so that such false positives can be flagged during the candidate vetting
process.Comment: 16 pages, 11 figures, 6 table
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