Bis[2-(morpholinometh­yl)phen­yl]phenyl­phosphane

The title compound, C28H33N2O2P, contains a penta­coordinated P atom as a result of the weak N→P intra­molecular inter­actions, with three C atoms, two N atoms and the lone pair arranged in a dicapped pseudo-tetra­hedral geometry. The morpholine rings exhibit an almost ideal chair conformation. In the crystal, two weak C—H⋯O hydrogen-bond inter­actions link the mol­ecules in layers stacked along the a axis; there are no further inter­actions between the layers

Organoselenium( II ) halides containing the pincer 2,6-(Me 2 NCH 2 ) 2 C 6 H 3 ligand – an experimental and theoretical investigation

New organoselenium( II )halidesofthetype[RSe] + X − [R = 2,6-(Me 2 NCH 2 ) 2 C 6 H 3 ;X=Cl( 2 ), Br ( 3 ), I ( 4 )] were prepared by cleavage of the Se – Se bond in R 2 Se 2 ( 1 )withSO 2 Cl 2 followed by halogen exchange when organo- selenium chloride was treated with NaBr or KI. The reaction between 2 and R ’ 2 MCl n resulted in new ionic [RSe] + [R ’ 2 MCl n +1 ] − [R ’ =2-(Me 2 NCH 2 )C 6 H 4 , n =1,M=Sb( 5 ), Bi ( 6 ); R ’ =Ph,M=Sb, n =1( 7 )or n =3( 8 )] species. All new compounds were investigated in solution by multinuclear NMR spectroscopy ( 1 H, 13 C, 77 Se, 2D experiments) and mass spectrometry. The ionic nature of 2 and the antimonates species was con fi rmed by conductivity studies. The molecular structures of [{2,6-(Me 2 NCH 2 ) 2 C 6 H 3 }Se] + Cl − · n H 2 O( 2 ·H 2 Oand 2 ·2H 2 O) and [{2,6-(Me 2 NCH 2 ) 2 C 6 H 3 }Se] + [Ph 2 SbCl 4 ] − ( 8 ), respectively, were established by single-crystal X-ray di ff raction, pointing out that the ionic nature of the se compounds is also preserved in the solid state, with both nitrogen atoms strongly trans coordinated to the selenium atom of the cation. Theoretical calculations carried out at the DFT level were exploite d to investigate the nature of the bonding in compounds 2 – 4 and the free cation [RSe] + ( 2a ). A topological analysis based on the theory of Atoms-In-Molecules (AIM) and Electron Localization Function (ELF) jointly to a Natural Bond Orbital (NBO) approach was used to shed light on the e ff ect of the nature of the halogen specie s X on the bonding within the 3c-4e N – Se – Nmoiet

[2-(4-Methyl­piperazin-1-ylmeth­yl)phen­yl]diphenyl­phosphane

In the title compound, C24H27N2P, the P atom is bonded to three C atoms in a trigonal–pyramidal geometry. The overall Ψ-trigonal-bipyramidal coordination of the P atom is established when the contribution of the electron lone pair and of the N—P donor–acceptor distance of 3.051 (3)Å are considered. The 4-methyl­piperazinyl ring adopts a chair conformation. Intra- and inter­molecular C—H⋯π hydrogen bonding leads to the consolidation of the structure

Substitutional disorder in a hypervalent diorganotin(IV) dihalide

The structure of bromidochloridobis[2-(dimethyl­amino­meth­yl)phen­yl]tin(IV), [SnBr0.65Cl1.35(C9H12N)2], contains two 2-(Me2NCH2)C6H4 units bonded to a Sn atom which lies on a twofold axis. The compound exhibits substitutional disorder of the halide atoms bonded to the Sn, with 1.35 occupancy for Cl and 0.65 for Br; it is isomorphous with the corresponding dichloride. The Sn atom is hexa­coordinated with a (C,N)2SnX 2 (X = Cl/Br) distorted octa­hedral core as a result of the strong intra­molecular N→Sn coordination trans to the Sn—X bonds (N1—Sn1—X1 = 165.8°). As a result of the inter­molecular contacts, viz. H⋯X and H⋯benzene inter­actions, the mol­ecules are arranged in a three-dimensional supra­molecular manner in the crystal structure

Bis(8-methyl-2,8-dicarba-closo-dodeca­boran-2-yl) tris­elenide

In the title compound, C6H26B20Se3, the geometry around the central Se atom is V-shaped, with the Se—Se—Se angle being 105.60 (4)°. The Se—Se bond lengths are consistent with single covalent bonds

Antitumour Organometallics. III. In Vivo Activity of Diphenylantimony(III) and Diorganotin(IV) Dithiophosphorus Derivatives Against P388 Leukemia

Diphenylantimony(III) and diorganotin(IV) derivatives of dithiophosphorus ligands, i.e. Ph2SbS2PR′2 (R′ = Ph, OPr-i) and R2Sn(S2PR′2)2 (R = n-Bu, Ph, R′ = Ph; R = Ph, R′ = OPr-i), have been screened against P388 leukemia in mice. All the compounds showed marginal activity towards this tumor system, some of them increasing the life span of the animals with more than 20%. The best results were obtained with (di-iso-propylphosphorodithioato)diphenylantimony(III) which exhibited a T/C value of 136%, at a dose of 5 mg/kg, administered on days 1,2 and 3 after tumor transplantation

Hydrogen bonding in substitutionally disordered di-μ-hydroxido-bis­{aqua­tri[bromido/chlorido(1/2)]tin(IV)} acetone disolvate

The structure of the title compound, [Sn2Br1.97Cl4.03(OH)2(H2O)2]·2C3H6O, contains two hexa­coordinated Sn atoms bridged symmetrically by two hydroxide groups, with an inversion center in the middle of the planar Sn2O2 ring, half of the mol­ecule being generated by inversion symmetry. The other sites of the distorted octa­hedral coordination geometry are occupied by halide atoms and water mol­ecules. The structure exhibits substitutional disorder of the halide atoms bonded to the Sn atom, with 0.672 (4) occupancy for Cl and 0.328 (4) for Br for each halide position. The compound crystallizes with two acetone mol­ecules, which are involved in intra- and inter­molecular O—H⋯O contacts. The water mol­ecules coordinated to the Sn atoms are also involved in O—H⋯O and O—H⋯X contacts, leading to a polymeric array along the a axis

Di-μ-chlorido-bis­{[2-(morpholinometh­yl)phenyl-κ2 C 1,N]palladium(II)}

The title compound, [Pd2(C11H14NO)2Cl2], has a dimeric structure with Cl atoms bridging the two Pd atoms, one half of the mol­ecule being generated by symmetry due to the crystallographic inversion centre located in the middle of the perfectly planar Pd2Cl2 ring. The five-membered ring adopts an envelope conformation, while the morpholino group has a chair conformation. The geometry around the metal centres is distorted square-planar, as a result of a strong intra­molecular N→Pd coordination trans to a Pd—Cl bond. In the crystal structure, the dimeric structure is strengthened by inter­molecular C—H⋯Cl hydrogen bonds. C—H⋯Cphen­yl inter­actions link the dimers into a columnar supra­molecular array along the a axis; the dimers are further connected by C—H⋯Ph inter­actions into a three-dimensional supra­molecular arrangement

Cibermarketing&Blog – a New Media Paradigm in the Development of Digital Culture

If 10 to 15 years ago the use of the internet for commercial and business purposes was considered improper, today hundred’s millions people are fervent users. The explanation for this impressive growth lays in the fact that the internet adds value both to the individual and the organizations. Marketing in a virtual world, using internet is not that different in concept from the traditional marketing, in the real world, but uses different ways to express itself and an unprecedented dynamics. The evolution of the marketing concepts has known a series of stages, from classical marketing to telemarketing (perform through phone exclusively) and cybermarketing (performed using the new information and communications technology).cybermarketing, blog, paradigm, digital culture, information and communication technology.

μ-Carbonato-bis­(bis­{2-[(diethyl­amino)­meth­yl]phen­yl}bis­muth(III))

The mol­ecular structure of the title compound, [Bi2(C11H16N)4(CO3)], consists of a symmetrically bridging carbonato group which binds two [2-Et2NCH2C6H4]2Bi units that are crystallographically related via a twofold rotation axis bis­ecting the carbonate group. The two Bi atoms and two of the C atoms directly bonded to bis­muth are quasi-planar [deviations of 0.323 (1) and 0.330 (9)Å for the Bi and C atoms, respectively] with the carbonate group. The remaining two ligands are in a trans arrangement relative to the quasi-planar (CBi)2CO3 system. The metal atom is strongly coordinated by the N atom of one pendant arm [Bi—N = 2.739 (6) Å], almost trans to the O atom, while the N atom of the other pendant arm exhibits a weaker intra­molecular inter­action [Bi⋯N = 3.659 (7) Å] almost trans to a C atom. If both these intra­molecular N→Bi inter­actions per metal atom are considered, the overall coordination geometry at bis­muth becomes distorted square-pyramidal [(C,N)2BiO cores] and the compound can be described as a hypervalent 12-Bi-5 species. Additional quite short intra­molecular Bi⋯O inter­actions are also present [3.796 (8)–4.020 (9) Å]. Inter­molecular associations through weak η6⋯Bi inter­actions [Bi⋯centroid of benzene ring = 3.659 (1) Å] lead to a ribbon-like supra­molecular association