6,547 research outputs found
The Effects of Negative Legacies on the Adjustment of Parentally Bereaved Children and Adolescents
This is a report of a qualitative analysis of a sample of bereaved families in which one parent died and in which children scored in the clinical range on the Child Behavior Check List. The purpose of this analysis was to learn more about the lives of these children. They were considered to be at risk of developing emotional and behavioral problems associated with the death. We discovered that many of these “high risk” children had a continuing bond with the deceased that was primarily negative and troubling for them in contrast to a comparison group of children not at risk from the same study. Five types of legacies, not mutually exclusive, were identified: health related, role related, personal qualities, legacy of blame, and an emotional legacy. Coping behavior on the part of the surviving parent seemed to make a difference in whether or not a legacy was experienced as negative
Hyperfine Level Splitting for Hydrogen-Like Ions due to Rotation-Spin Coupling
The theoretical aspects of spin-rotation coupling are presented. The approach
is based on the general covariance principle. It is shown that the
gyrogravitational ratio of the bare spin-1/2 and the spin-1 particles is equal
unity. That is why spin couples with rotation as an ordinary angular momentum.
This result is the rigorous substantiation of the cranking model. To observe
the phenomenon, the experiment with hydrogen-like ions in a storage ring is
suggested. It is found that the splitting of the
hyperfine state of the and ions
circulating in the storage ring ESR in Darmstadt along a helical trajectory is
about 4.5 MHz. We argue that such splitting can be experimentally determined by
means of the ionic interferometry.Comment: 6 pages, final versio
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Turning points: the personal and professional circumstances that lead academics to become middle managers
In the current higher education climate, there is a growing perception that the pressures associated with being an academic middle manager outweigh the perceived rewards of the position. This article investigates the personal and professional circumstances that lead academics to become middle managers by drawing on data from life history interviews undertaken with 17 male and female department heads from a range of disciplines, in a post-1992 UK university. The data suggests that experiencing conflict between personal and professional identities, manifested through different socialization experiences over time, can lead to a ‘turning point’ and a decision that affects a person’s career trajectory. Although the results of this study cannot be generalized, the findings may help other individuals and institutions move towards a firmer understanding of the academic who becomes head of department—in relation to theory, practice and research
Theory of the propagation of coupled waves in arbitrarily-inhomogeneous stratified media
We generalize the invariant imbedding theory of the wave propagation and
derive new invariant imbedding equations for the propagation of arbitrary
number of coupled waves of any kind in arbitrarily-inhomogeneous stratified
media, where the wave equations are effectively one-dimensional. By doing this,
we transform the original boundary value problem of coupled second-order
differential equations to an initial value problem of coupled first-order
differential equations, which makes the numerical solution of the coupled wave
equations much easier. Using the invariant imbedding equations, we are able to
calculate the matrix reflection and transmission coefficients and the wave
amplitudes inside the inhomogeneous media exactly and efficiently. We establish
the validity and the usefulness of our results by applying them to the
propagation of circularly-polarized electromagnetic waves in one-dimensional
photonic crystals made of isotropic chiral media. We find that there are three
kinds of bandgaps in these structures and clarify the nature of these bandgaps
by exact calculations.Comment: 7 pages, 1 figure, to appear in Europhys. Let
The cosmic growth of the active black hole population at 1<z<2 in zCOSMOS, VVDS and SDSS
We present a census of the active black hole population at 1<z<2, by
constructing the bivariate distribution function of black hole mass and
Eddington ratio, employing a maximum likelihood fitting technique. The study of
the active black hole mass function (BHMF) and the Eddington ratio distribution
function (ERDF) allows us to clearly disentangle the active galactic nuclei
(AGN) downsizing phenomenon, present in the AGN luminosity function, into its
physical processes of black hole mass downsizing and accretion rate evolution.
We are utilizing type-1 AGN samples from three optical surveys (VVDS, zCOSMOS
and SDSS), that cover a wide range of 3 dex in luminosity over our redshift
interval of interest. We investigate the cosmic evolution of the AGN population
as a function of AGN luminosity, black hole mass and accretion rate. Compared
to z = 0, we find a distinct change in the shape of the BHMF and the ERDF,
consistent with downsizing in black hole mass. The active fraction or duty
cycle of type-1 AGN at z~1.5 is almost flat as a function of black hole mass,
while it shows a strong decrease with increasing mass at z=0. We are witnessing
a phase of intense black hole growth, which is largely driven by the onset of
AGN activity in massive black holes towards z=2. We finally compare our results
to numerical simulations and semi-empirical models and while we find reasonable
agreement over certain parameter ranges, we highlight the need to refine these
models in order to match our observations.Comment: 31 pages, 28 figures, accepted for publication in MNRA
A Flux-Limited Sample of z~1 Ly-alpha Emitting Galaxies in the CDFS
We describe a method for obtaining a flux-limited sample of Ly-alpha emitters
from GALEX grism data. We show that the multiple GALEX grism images can be
converted into a three-dimensional (two spatial axes and one wavelength axis)
data cube. The wavelength slices may then be treated as narrowband images and
searched for emission-line galaxies. For the GALEX NUV grism data, the method
provides a Ly-alpha flux-limited sample over the redshift range z=0.67-1.16. We
test the method on the Chandra Deep Field South field, where we find 28
Ly-alpha emitters with faint continuum magnitudes (NUV>22) that are not present
in the GALEX pipeline sample. We measure the completeness by adding artificial
emitters and measuring the fraction recovered. We find that we have an 80%
completeness above a Ly-alpha flux of 10^-15 erg/cm^2/s. We use the UV spectra
and the available X-ray data and optical spectra to estimate the fraction of
active galactic nuclei in the selection. We report the first detection of a
giant Ly-alpha blob at z<1, though we find that these objects are much less
common at z=1 than at z=3. Finally, we compute limits on the z~1 Ly-alpha
luminosity function and confirm that there is a dramatic evolution in the
luminosity function over the redshift range z=0-1.Comment: 18 pages, in press at The Astrophysical Journa
Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L
Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans. These viruses encode conserved replicase and structural proteins as well as more diverse accessory proteins, encoded in the 3′ ends of their genomes, that often act as host cell antagonists. We previously showed that 2′,5′-phosphodiesterases (2′,5′-PDEs) encoded by the prototypical Betacoronavirus, mouse hepatitis virus (MHV), and by Middle East respiratory syndrome-associated coronavirus antagonize the oligoadenylate-RNase L (OAS-RNase L) pathway. Here we report that additional coronavirus superfamily members, including lineage A betacoronaviruses and toroviruses infecting both humans and animals, encode 2′,5′-PDEs capable of antagonizing RNase L. We used a chimeric MHV system (MHV(Mut)) in which exogenous PDEs were expressed from an MHV backbone lacking the gene for a functional NS2 protein, the endogenous RNase L antagonist. With this system, we found that 2′,5′-PDEs encoded by the human coronavirus HCoV-OC43 (OC43; an agent of the common cold), human enteric coronavirus (HECoV), equine coronavirus (ECoV), and equine torovirus Berne (BEV) are enzymatically active, rescue replication of MHV(Mut) in bone marrow-derived macrophages, and inhibit RNase L-mediated rRNA degradation in these cells. Additionally, PDEs encoded by OC43 and BEV rescue MHV(Mut) replication and restore pathogenesis in wild-type (WT) B6 mice. This finding expands the range of viruses known to encode antagonists of the potent OAS-RNase L antiviral pathway, highlighting its importance in a range of species as well as the selective pressures exerted on viruses to antagonize it. IMPORTANCE Viruses in the family Coronaviridae include important human and animal pathogens, including the recently emerged viruses severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and Middle East respiratory syndrome-associated coronavirus (MERS-CoV). We showed previously that two viruses within the genus Betacoronavirus, mouse hepatitis virus (MHV) and MERS-CoV, encode 2′,5′-phosphodiesterases (2′,5′-PDEs) that antagonize the OAS-RNase L pathway, and we report here that these proteins are furthermore conserved among additional coronavirus superfamily members, including lineage A betacoronaviruses and toroviruses, suggesting that they may play critical roles in pathogenesis. As there are no licensed vaccines or effective antivirals against human coronaviruses and few against those infecting animals, identifying viral proteins contributing to virulence can inform therapeutic development. Thus, this work demonstrates that a potent antagonist of host antiviral defenses is encoded by multiple and diverse viruses within the family Coronaviridae, presenting a possible broad-spectrum therapeutic target
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