277 research outputs found

    A PRÁTICA DA PESQUISA NA FORMAÇÃO DOCENTE: CONCEPÇÕES DE PROFESSORES DE LICENCIATURA EM MATEMÁTICA DE UMA UNIVERSIDADE NO CONTEXTO DA AMAZÔNIA BRASILEIRA

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    This article is presented with the purpose of highlight some reflections on the reality of research practice in training initial teacher of Mathematics. Having such problem, investigate and analyze the conceptions of teachers-trainers on the practice of research in Mathematics degree, the research presented by this paper was based methodological on approach qualitative of character interpretative, basing on the use of a questionnaire as a tool for data collection, applied at each of the participating teachers of research, allowing obtain information about their conceptions about the practice of research in training teacher of Mathematics. The subjects of research consisted of six teachers-trainers of the course of degree in Mathematics of University Federal of Rondônia (UNIR), Campus of Ji-Paraná. In response to the problem of present research, it can be concluded that the surveyed teachers understand the meaning of research, relating primarily to the scientific research. These teachers also emphasize the importance of research practice to the personal and professional formation of the undergraduates in mathematics and it is possible to teach mathematics through research. In more, also demonstrate recognize the responsibility of the University forward the context of academic and scientific research, and that despite the difficulties to promote and actualize the practice of research in the scope university, have struggled in the sense that their researches will contribute to their teaching activities and professional qualification and consequently to the formation of undergraduates in Mathematics.Este artigo se apresenta com o propósito de evidenciar algumas reflexões sobre a realidade da prática da pesquisa na formação inicial de professores de Matemática. Tendo como problemática, investigar e analisar quais as concepções de professores-formadores sobre a prática da pesquisa na Licenciatura em Matemática, a pesquisa apresentada através desse artigo fundamentou-se metodologicamente na abordagem qualitativa de caráter interpretativo, embasando-se na utilização de um questionário como instrumento de coleta de dados, aplicado junto a cada um dos professores participantes da investigação, permitindo obter informações sobre as suas concepções a respeito da prática da pesquisa na formação de professores de Matemática. Os sujeitos da pesquisa constituíram-se de seis professores-formadores do curso de Licenciatura em Matemática da Universidade Federal de Rondônia (UNIR), Campus de Ji-Paraná. Em resposta à problemática da presente investigação, pode-se concluir que os professores pesquisados compreendem o significado de pesquisa, relacionando-a principalmente à investigação científica. Esses professores destacam ainda a importância da prática da pesquisa para a formação pessoal e profissional dos licenciandos em Matemática e que é possível ensinar Matemática através da pesquisa. No mais, também demonstram reconhecer a responsabilidade da Universidade frente o contexto da pesquisa acadêmico-científica, e que apesar das dificuldades de se promover e efetivar a prática da pesquisa no âmbito universitário, têm se esforçado no sentido de que suas pesquisas contribuam para suas atividades docentes e qualificação profissional e consequentemente para a formação dos licenciandos em Matemática

    A PRÁTICA DA PESQUISA NA FORMAÇÃO DOCENTE: CONCEPÇÕES DE PROFESSORES DE LICENCIATURA EM MATEMÁTICA DE UMA UNIVERSIDADE NO CONTEXTO DA AMAZÔNIA BRASILEIRA

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    This article is presented with the purpose of highlight some reflections on the reality of research practice in training initial teacher of Mathematics. Having such problem, investigate and analyze the conceptions of teachers-trainers on the practice of research in Mathematics degree, the research presented by this paper was based methodological on approach qualitative of character interpretative, basing on the use of a questionnaire as a tool for data collection, applied at each of the participating teachers of research, allowing obtain information about their conceptions about the practice of research in training teacher of Mathematics. The subjects of research consisted of six teachers-trainers of the course of degree in Mathematics of University Federal of Rondônia (UNIR), Campus of Ji-Paraná. In response to the problem of present research, it can be concluded that the surveyed teachers understand the meaning of research, relating primarily to the scientific research. These teachers also emphasize the importance of research practice to the personal and professional formation of the undergraduates in mathematics and it is possible to teach mathematics through research. In more, also demonstrate recognize the responsibility of the University forward the context of academic and scientific research, and that despite the difficulties to promote and actualize the practice of research in the scope university, have struggled in the sense that their researches will contribute to their teaching activities and professional qualification and consequently to the formation of undergraduates in Mathematics.Este artigo se apresenta com o propósito de evidenciar algumas reflexões sobre a realidade da prática da pesquisa na formação inicial de professores de Matemática. Tendo como problemática, investigar e analisar quais as concepções de professores-formadores sobre a prática da pesquisa na Licenciatura em Matemática, a pesquisa apresentada através desse artigo fundamentou-se metodologicamente na abordagem qualitativa de caráter interpretativo, embasando-se na utilização de um questionário como instrumento de coleta de dados, aplicado junto a cada um dos professores participantes da investigação, permitindo obter informações sobre as suas concepções a respeito da prática da pesquisa na formação de professores de Matemática. Os sujeitos da pesquisa constituíram-se de seis professores-formadores do curso de Licenciatura em Matemática da Universidade Federal de Rondônia (UNIR), Campus de Ji-Paraná. Em resposta à problemática da presente investigação, pode-se concluir que os professores pesquisados compreendem o significado de pesquisa, relacionando-a principalmente à investigação científica. Esses professores destacam ainda a importância da prática da pesquisa para a formação pessoal e profissional dos licenciandos em Matemática e que é possível ensinar Matemática através da pesquisa. No mais, também demonstram reconhecer a responsabilidade da Universidade frente o contexto da pesquisa acadêmico-científica, e que apesar das dificuldades de se promover e efetivar a prática da pesquisa no âmbito universitário, têm se esforçado no sentido de que suas pesquisas contribuam para suas atividades docentes e qualificação profissional e consequentemente para a formação dos licenciandos em Matemática

    Biologically-active compounds from Brazilian lichens and their affinity with ether

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    It can be obtained from lichens biologically-active extracts and pure substances, many of them of phenolic nature. They are usually obtained by using organic solvents, such as diethyl ether. In this paper the usefulness of ether for the obtainment of crude extracts and the subsequent purification of pure substances from Brazilian lichen is reviewed, as well as alternatives to their production through cells or thallus immobilization in bioreactors and their entrapment in inert matrix

    Histological evaluation of the liver of mice with sarcoma-180 treated with salazinic acid

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    Abstract Many of the drugs used to fight cancer cells induce various damage causing hepatotoxic effects which are characterized by tissue changes. The aim of the study is to know the possible effects of salazinic acid on livers of mice exposed to Sacoma-180. The tumor was grown in the animals in ascitic form and inoculated subcutaneously in the axillary region of the mouse developing the solid tumor. Treatment with salazinic acid (25 and 50 mg/kg) and 5-Fluorouracil (20 mg/kg) started 24-hours after inoculation and was performed for 7 days. To verify these effects, the qualitative method of histological criteria investigated in liver tissue was used. It was observed that all treated groups showed an increase of pyknotic nuclei in relation to the negative control. There was an increase in steatosis in all groups compared to the negative control but there was a decrease in the groups treated with salazinic acid in the 5-Fluorouracil. There was no necrosis in the salazinic acid treated groups. However, this effect was seen in 20% of the positive control group. Therefore, it can be concluded that salazinic acid did not show hepatoprotective action on mice but demonstrated a decrease in steatosis and absence of tissue necrosis

    Storage methods, phenolic composition, and bioactive properties of Apis mellifera and Trigona spinipes pollen

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    The aim of this study was to evaluate the influence of lyophilization and drying in stove on phenolic compounds content and the biological activity of Apis mellifera and Trigona spinipes pollens produced in Brazil. In general, the bee pollen produced by T. spinipes presented highest antioxidant activity in dried and fresh samples assessed either by test of plasma ferric reduction capacity (FRAP) and free radical scavenging assay (DPPH) methods. For A. mellifera bee pollen the antioxidant activity was higher on the fresh samples. Nevertheless, b-carotene bleaching assay (BCB) and linoleic acid content were higher in T. spinipes samples, mainly in the fresh ones. Higher antioxidant activity was owing to higher content in phenolic compounds. Lyophilization method was the best for phenolic compounds’ conservation for both species. The bee pollen of both species has a high amount of flavonoids: kaempferol-3-O-glucoside was the most abundant in A. mellifera while for T. spinipes the most prevalent was resorcylic acidþepicatechin. All extracts presented antibacterial activity against Saphylococcus aureus (ATCC 43300)TM, (ESA 83138150), (ESA 32), Pseudomonas aeruginosa (ATCC 15442)TM, Pseudomonas aeruginosa (MRC.4) and (MRC.10). The methods used for storage influenced the biological properties of bee pollen from both species. Regarding the content of phenolic compounds, differences were observed amongst the pollen types: for A. mellifera these were best preserved with lyophilization, while for T. spinipes the three storage methods were equivalent.The authors are grateful to the Coordenac¸~ao de Aperfeic¸oamento de Pessoal de N ıvel Superior – CAPES (88881.062167/2014-01 for M.L.M.E.). A. Pascoal would like to thank Foundation for Science and Technology (FCT, Portugal), Programa Operacional Potencial Humano (POPH), and European Union (EU) for his Postdoctoral grant SFRH/BPD/ 91380/2012.info:eu-repo/semantics/publishedVersio

    Levantamento preliminar de térmitas em bosques de mangues na Reserva Ecológica da Michelin, Igrapiúna, Bahia, Brasil

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    Aiming at providing a background for the establishment of a Management and Conservation Plan for the Michelin Ecological Reserve, located in Camamu Bay, Bahia State, we analyzed the diversity and structure of termite communities occurring in mangrove vegetation in this area. Five 3 x 100 m unconnected transects were setup, each one subdivided in 10 sections measuring 3 x 10 m. Three morphospecies, belonging to two genera of termites, were found: Nasutitermes sp1 (64,71%), Nasutitermes sp2 (23,53%) e Termes sp (11,76%), present in 17 samples. Nasutitermes was the most abundant genus, as a result of the wide ecological valence demonstrated by this taxonomic group, which is able to build epigeic or tree nests, increasing the likelihood of mangrove colonization, an environment constantly flooded and soaked.Com o propósito de fornecer subsídios para a criação do plano de Manejo e Conservação da Reserva Ecológica da Michelin, localizada na Bahia de Camamú-Ba, analisamos a diversidade e a estrutura da comunidade de cupins que ocorrem em bosques de manguezais daquela localidade. Foram demarcados 5 transectos não conectados, com 3m x 100m, subdivididos em 10 seções de 3m x 10m. Foram encontradas 3 morfoespécies de 2 gêneros de cupins: Nasutitermes sp1 (64,71%), Nasutitermes sp2 (23,53%) e Termes sp. (11,76%) num total de 17 amostras coletadas. Nasutitermes foi o gênero mais abundante, resultado da ampla valência ecológica demonstrada por este grupo, capaz de construir ninhos epígeos ou arborícolas, ampliando a possibilidade de colonização em manguezal, cujo solo se mantém periodicamente inundado e encharcado

    Antifungal activity of synthetic naphthoquinones against dermatophytes and opportunistic fungi: Preliminary mechanism-of-action tests

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    This study evaluated the antifungal activities of synthetic naphthoquinones against opportunistic and dermatophytic fungi and their preliminary mechanisms of action. The minimum inhibitory concentrations (MICs) of four synthetic naphthoquinones for 89 microorganisms, including opportunistic yeast agents, dermatophytes and opportunistic filamentous fungi, were determined. The compound that exhibited the best activity was assessed for its action against the cell wall (sorbitol test), for interference associated with ergosterol interaction, for osmotic balance (K+ efflux) and for membrane leakage of substances that absorb at the wavelength of 260 nm. All tested naphthoquinones exhibited antifungal activity, and compound IVS320 (3a,10b-dihydro-1H-cyclopenta [b] naphtho [2,3-d] furan-5,10-dione)-dione) demonstrated the lowest MICs across the tested species. The MIC of IVS320 was particularly low for dermatophytes (values ranging from 5-28 μg/mL) and Cryptococcus spp. (3-5 μg/mL). In preliminary mechanism-of-action tests, IVS320 did not alter the fungal cell wall but did cause problems in terms of cell membrane permeability (efflux of K+ and leakage of substances that absorb at 260 nm). This last effect was unrelated to ergosterol interactions with the membrane. © 2014 Ferreira et al

    Antifungal activity of synthetic naphthoquinones against dermatophytes and opportunistic fungi: Preliminary mechanism-of-action tests

    Get PDF
    This study evaluated the antifungal activities of synthetic naphthoquinones against opportunistic and dermatophytic fungi and their preliminary mechanisms of action. The minimum inhibitory concentrations (MICs) of four synthetic naphthoquinones for 89 microorganisms, including opportunistic yeast agents, dermatophytes and opportunistic filamentous fungi, were determined. The compound that exhibited the best activity was assessed for its action against the cell wall (sorbitol test), for interference associated with ergosterol interaction, for osmotic balance (K+ efflux) and for membrane leakage of substances that absorb at the wavelength of 260 nm. All tested naphthoquinones exhibited antifungal activity, and compound IVS320 (3a,10b-dihydro-1H-cyclopenta [b] naphtho [2,3-d] furan-5,10-dione)-dione) demonstrated the lowest MICs across the tested species. The MIC of IVS320 was particularly low for dermatophytes (values ranging from 5-28 μg/mL) and Cryptococcus spp. (3-5 μg/mL). In preliminary mechanism-of-action tests, IVS320 did not alter the fungal cell wall but did cause problems in terms of cell membrane permeability (efflux of K+ and leakage of substances that absorb at 260 nm). This last effect was unrelated to ergosterol interactions with the membrane. © 2014 Ferreira et al
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