814 research outputs found
Work-related basic need satisfaction as a predictor of work engagement among academic staff in Turkey
This study examines the relationship between work-related basic need satisfaction and work engagement. Data were obtained from a total of 203 academics who are employed in various universities of Turkey. In this research Work-Related Basic Need Satisfaction Scale and The Turkish Form of Utrecht Work Engagement Scale were utilized. The data were analysed through multiple regression and Pearson product-moment correlation coefficient analysis methods. The findings revealed that the sub-dimensions of work-related basic need satisfaction significantly predicted work engagement. Upper management should improve work conditions of their personnel, which are related with competency, autonomy, and relatedness needs of academics. This way, academic staff will have better efficiency in terms of work engagement, which will also result in higher work adaptation and participation.Keywords: academic staff, basic need satisfaction, work engagemen
Polycystic Kidney Disease with Renal failure Presenting as Incarcerated Inguinal Hernia in the ED
Autosomal dominant polycystic kidney disease may present to the emergency department (ED) with vomiting, abdominal pain or hernias, renal insufficiency or failure, or bleeding from cerebral aneurysms. A 37-year-old man presented to the ED with signs and symptoms of incarcerated inguinal hernia. Laboratory studies showed renal failure with anion gap acidosis, and bedside ultrasound showed multicystic kidneys. Computed tomography confirmed the diagnosis. Emergency physicians should be aware of this common connective tissue defect and its serious associated conditions
Flipping quantum coins
Coin flipping is a cryptographic primitive in which two distrustful parties
wish to generate a random bit in order to choose between two alternatives. This
task is impossible to realize when it relies solely on the asynchronous
exchange of classical bits: one dishonest player has complete control over the
final outcome. It is only when coin flipping is supplemented with quantum
communication that this problem can be alleviated, although partial bias
remains. Unfortunately, practical systems are subject to loss of quantum data,
which restores complete or nearly complete bias in previous protocols. We
report herein on the first implementation of a quantum coin-flipping protocol
that is impervious to loss. Moreover, in the presence of unavoidable
experimental noise, we propose to use this protocol sequentially to implement
many coin flips, which guarantees that a cheater unwillingly reveals
asymptotically, through an increased error rate, how many outcomes have been
fixed. Hence, we demonstrate for the first time the possibility of flipping
coins in a realistic setting. Flipping quantum coins thereby joins quantum key
distribution as one of the few currently practical applications of quantum
communication. We anticipate our findings to be useful for various
cryptographic protocols and other applications, such as an online casino, in
which a possibly unlimited number of coin flips has to be performed and where
each player is free to decide at any time whether to continue playing or not.Comment: 17 pages, 3 figure
Crash Injury Prediction and Vehicle Damage Reporting by Paramedics
Objective: The accuracy of pre-hospital crash scene details and crash victim assessment has important implications for initial trauma care assessment and management. Similarly, it is known to influence physician perception of crash victim injury severity. The goal of this feasibility study was to examine paramedic accuracy in predicting crash victim injury profile, disability outcome at hospital discharge, and reporting vehicle damage with other crash variables.Methods: This prospective case series study was undertaken at a Southern California, Level I trauma center certified by the American College of Surgeons. Paramedics transporting crash injured motor vehicle occupants to our emergency department (ED)/trauma center were surveyed. We abstracted ED and in-patient records of injured vehicle occupants. Vehicle and crash scene data were obtained from a professional crash reconstruction, which included the assessment of deformation, crash forces, change in velocity, and the source of each injury.Results: We used survey, injury, and crash reconstruction data from 22 collision cases in the final analysis. The median Injury Severity Score (ISS) was five (range 1-24). No enrolled patients died, and none were severely disabled at the time of discharge from the hospital. The paramedic crash injury severity predictions were sensitive for an Abbreviated Injury Scale (AIS) of 2-4. Paramedics often agreed with the crash reconstruction on restraint use, ejection, and other fatalities at the scene, and had lower levels of agreement for front airbag deployment, steering wheel damage, and window/windshield impact. Paramedics had 80% accuracy in predicting any disability at the time of hospital discharge.Conclusion: Paramedic prediction of injury profile was sensitive, and prediction of disability outcome at discharge was accurate when compared to discharge diagnosis. Their reporting of vehicle specific crash variables was less accurate. Further study should be undertaken to assess the benefits of crash biomechanics education for paramedics and other pre-hospital care providers. [WestJEM. 2009;10:62-67.
Fully Distrustful Quantum Cryptography
In the distrustful quantum cryptography model the different parties have
conflicting interests and do not trust one another. Nevertheless, they trust
the quantum devices in their labs. The aim of the device-independent approach
to cryptography is to do away with the necessity of making this assumption,
and, consequently, significantly increase security. In this paper we enquire
whether the scope of the device-independent approach can be extended to the
distrustful cryptography model, thereby rendering it `fully' distrustful. We
answer this question in the affirmative by presenting a device-independent
(imperfect) bit-commitment protocol, which we then use to construct a
device-independent coin flipping protocol
Regulation of pituitary MT1 melatonin receptor expression by gonadotrophin-releasing hormone (GnRH) and early growth response factor-1 (Egr-1) : in vivo and in vitro studies
Copyright: © 2014 Bae et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was funded by the UK Biotechnology and Biological Sciences Research Council (BBSRC; grant BB/F020309/1; http://www.bbsrc.ac.uk/home/home.aspx). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype
The aim of this study was to investigate HLA class II associations in polymyositis (PM) and dermatomyositis (DM), and to determine how these associations influence clinical and serological differences. DNA samples were obtained from 225 UK Caucasian idiopathic inflammatory myopathy patients (PM = 117, DM = 108) and compared with 537 randomly selected UK Caucasian controls. All cases had also been assessed for the presence of related malignancy and interstitial lung disease (ILD), and a number of myositis-specific/myositis-associated antibodies (MSAs/MAAs). Subjects were genotyped for HLA-DRB1, DQA1 and DQB1. HLA-DRB1*03, DQA1*05 and DQB1*02 were associated with an increased risk for both PM and DM. The HLA-DRB1*03-DQA1*05-DQB1*02 haplotype demonstrated strong association with ILD, irrespective of myositis subtype or presence of anti-aminoacyl-transfer RNA synthetase antibodies. The HLA-DRB1*07-DQA1*02-DQB1*02 haplotype was associated with risk for anti-Mi-2 antibodies, and discriminated PM from DM (odds ratio 0.3, 95% confidence interval 0.1–0.6), even in anti-Mi-2 negative patients. Other MSA/MAAs showed specific associations with other HLA class II haplotypes, irrespective of myositis subtype. There were no genotype, haplotype or serological associations with malignancy. The HLA-DRB1*03-DQA1*05-DQB1*02 haplotype associations appear to not only govern disease susceptibility in Caucasian PM/DM patients, but also phenotypic features common to PM/DM. Though strongly associated with anti-Mi-2 antibodies, the HLA-DRB1*07-DQA1*02-DQB1*02 haplotype shows differential associations with PM/DM disease susceptibility. In conclusion, these findings support the notion that myositis patients with differing myositis serology have different immunogenetic profiles, and that these profiles may define specific myositis subtypes
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