Habilidades básicas del pensamiento matemático en niños de cinco años de una institución educativa inicial, Los Olivos 2019

Es muy importante que los niños desde muy pequeños tengan un dominio del pensamiento matemático, ya que hoy en día viven en un mundo donde nos comunicamos matemáticamente, es por ello que el objetivo de esta investigación es, determinar el nivel del pensamiento matemático en niños de cinco años, teniendo como dimensiones : el razonamiento matemático, descubrimiento de la geometría y el ámbito numérico, puesto que son la base para poder construir conocimientos matemáticos que todo infante debe obtener para contar con un correcto lenguaje matemático, es así que se tomó consideración los siguientes indicadores : asociaciones por pareja, selección y clasificación , el orden , sucesiones , el conocimiento general del espacio, la geometría en el espacio , el espacio al plano , comparación de conjuntos , la enumeración , escritura en cifras. El tipo de investigación fue básico, con un diseño no experimental, esta investigación está conformada por 80 niños, con una muestra de 20 niños. Se utilizo como instrumento una ficha de observación. Para poder aplicar dicho instrumento se validó por un juicio de expertos y la confiabilidad para la escala valorativa se consideró el Alfa de Cronbach, cuyo valor obtenido fue de ,954 indicando un resultado elevado para la aplicación del instrumento. Igualmente, se determinó el nivel de las habilidades básicas en niños de cinco años, Los Olivos 2019

José de la Riva Agüero y Osma. Un exiliado latinoamericano a comienzos del siglo XX

This text reconstructs the trajectory of Dr. José de la Riva Agüero and Osma, one of the benchmarks of Peruvian intellectuality of the first half of the twentieth century, which is going through a process ofexile in the twenties. His biography has been elaborated on the basis of specialized literature and his own work, which has allowed us to meet the character within his generation and relate it to other university students of importance to Peru and Latin america.Este texto reconstruye la trayectoria del Dr. José de la Riva Agüero y Osma, uno de los referentes de la intelectualidad peruana de la primera mitad del siglo xx, que atraviesa un proceso de exilio en losaños veinte. Su biografía, ha sido elaborada en base a bibliografía especializada y a su propia obra, la que nos ha permitido conocer al personaje dentro de su generación y relacionarlo con otros estudiantes universitariosde importancia para Perú y América Latina

Enfrentamiento de exigencias del Teletrabajo en Pandemia Covid-19

Se revisa el despliegue de estrategias de enfrentamiento presentes en el trabajo remoto en contexto de la pandemia por Covid-19. Se entrevistaron 23 personas que se encuentran recientemente teletrabajando. Los resultados muestran que las personas experimentaban cierta desestructuración de su actividad laboral y vida personal, tendiendo a desarrollar estrategias reactivas y adaptativas. Se concluye que, responder a las exigencias que impone el teletrabajo, supone no sólo la adaptación de los/as teletrabajadores/as, sino que igualmente condiciones que fomenten la apropiación constructiva de las posibilidades que abre el trabajo remoto. -- The deployment of coping strategies present in remote work in the context of Covid-19 pandemic is reviewed. 23 people who are recently teleworking were interviewed, Results show that people would experience a certain destructure of their work activity and personal life, tending to develop reactive and adaptive strategies. It is concluded that responding to the demands imposed by teleworking implies not only the adaptation of teleworkers but also conditions that foster the constructive appropriation of the possibilities that remote work opens

A longitudinal study of CMT1A using Rasch analysis based CMT neuropathy and examination scores

Objective: To evaluate the sensitivity of Rasch analysis-based, weighted Charcot-Marie-Tooth Neuropathy and Examination Scores (CMTNS-R and CMTES-R) to clinical progression in patients with Charcot-Marie-Tooth disease type 1A (CMT1A). Methods: Patients with CMT1A from 18 sites of the Inherited Neuropathies Consortium were evaluated between 2009 and 2018. Weighted CMTNS and CMTES modified category responses were developed with Rasch analysis of the standard scores. Change from baseline for CMTNS-R and CMTES-R was estimated with longitudinal regression models. Results: Baseline CMTNS-R and CMTES-R scores were available for 517 and 1,177 participants, respectively. Mean ± SD age of participants with available CMTES-R scores was 41 ± 18 (range 4–87) years, and 56% were female. Follow-up CMTES-R assessments at 1, 2, and 3 years were available for 377, 321, and 244 patients. A mixed regression model showed significant change in CMTES-R score at years 2 through 6 compared to baseline (mean change from baseline 0.59 points at 2 years, p = 0.0004, n = 321). Compared to the original CMTES, the CMTES-R revealed a 55% improvement in the standardized response mean (mean change/SD change) at 2 years (0.17 vs 0.11). Change in CMTES-R at 2 years was greatest in mildly to moderately affected patients (1.48-point mean change, 95% confidence interval 0.99–1.97, p < 0.0001, for baseline CMTES-R score 0–9). Conclusion: The CMTES-R demonstrates change over time in patients with CMT1A and is more sensitive than the original CMTES. The CMTES-R was most sensitive to change in patients with mild to moderate baseline disease severity and failed to capture progression in patients with severe CMT1A. ClinicalTrials.gov identifier NCT01193075

Griffonia simplicifolia I: Fluorescent tracer for microcirculatory vessels in nonperfused thin muscles and sectioned muscle

Previous studies on mice have revealed that the Griffonia simplicifolia I (GSI) lectin selectively binds to capillaries in a number of microvascular beds. These observations suggest that the lectin might be a suitable microvascular marker for physiological studies of skeletal muscle, particularly when fluorescent visualization of vessels is desired independently of their perfusion status. Since species and strain heterogeneity has been demonstrated for certain lectins associated with the microcirculatory vessels, lectin binding was studied in a number of muscles taken from the major species of mammals used for experimental purposes. Staining of cryostal sections confirmed the utility of GSI as a marker for capillaries from muscle of mice, rats, hamsters, rabbits, dogs, and monkeys. Differential staining of arterioles and veins was revealed by double labeling with GSI and antisera to Factor VIII-related antigen. Double labeling for GSI binding and alkaline phosphatase activity revealed that the GSI method detects many more capillaries and terminal arterioles than does the alkaline phosphatase method. GSI binding to unfixed whole mounts of thin skeletal muscles (hamster cheek pouch, mouse diaphragm, and rat cremaster) was studied to determine whether the GSI lectin would be a suitable marker for intravital studies. An extensive microvascular bed, including terminal arterioles, venules, and capillaries, was revealed which could be visualized in the complete absence of perfusion with fluorescent markers. These observations suggest that the GSI lectin may be extremely useful as a probe for the microcirculation of skeletal muscle in many types of physiological experiments.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/27080/1/0000071.pd