PROXIMATE COMPOSITION, NUTRITIVE VALUE AND EVALUATION OF ANTIOXIDANT POTENTIAL OF STEM OF DRACAENA REFLEXA LAM

Objective: The stem of Dracaena reflexa was analyzed for preliminary phytochemical screening, proximate composition, nutritive value, total phenolic content and antioxidant potential.Methods: Preliminary phytochemical screening, proximate analysis, nutritive value were evaluated using standard methods. Total phenols were calculated by folin ciocalteu method. The antioxidant activity was performed by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay and ferric reducing antioxidant power (FRAP) assay.Results: Phytochemical screening revealed the presence of various medicinal active phytoconstituent like alkaloids, flavonoids, glycosides, tannins etc. Total phenolic content was highest for dichloromethane extract (73.48mGAE/g dry weight). Proximate analysis showed content of ash (8.015%), moisture (3.31%), fat (0.97%), fiber (1.31%), protein (3.70%), carbohydrate (86.01%) and nutritive value (367.56 Kcal/100grams of stems). In DPPH assay highest activities shown by dichloromethane extract with IC50 values of 0.46 mg/ml and also have FRAP value 2.071.Conclusion: Overall results revealed that Dracaena reflexa stem exhibits excellent nutritive value along with potent antioxidant activity and can be used in medicine as well as in food supplements to prevent the oxidation and rancidity of food.Â

MUDHAGARBHA W.S.R. OBSTRUCTED LABOUR AND ITS APPLIED ASPECT

Maternal and Infant mortality is still a big problem in Modern scenario. Different complications during preconception, antenatal, intranatal and postnatal period are increasing day by day. Ayurveda has given prime importance to Antenatal and Intranatal care of women and her baby. In spite of good care sometimes labour has unpredictable outcomes, previously normal labour suddenly landed up into abnormal or obstructed labour. In Ayurveda, obstructed labour has unique concepts and is explained under the term Mudagarbha. Obstructed labour is also a cause of maternal and infant death. In the present article an attempt is made to throw light on the very unique concept of Mudhagarbha described in Ayurveda and its scientific Concept

Confinement study of an SU(4) gauge theory with fermions in multiple representations

We discuss the phase diagnostics used in our finite-temperature study of an SU(4) gauge theory with dynamical fermions in both the fundamental and two-index antisymmetric representations. Beyond the usual Polyakov loop diagnostics of confinement, we employ several Wilson flow phase diagnostics. The first, what we call the "flow anisotropy", is known in the literature: the deconfinement transition introduces anisotropy between the spatial and temporal directions, to which the flow is extremely sensitive. The second, the "long flow time Polyakov loop," is related but novel. While we do not claim to fully understand this diagnostic, we have empirically found it to be useful as an unusually sharp diagnostic of phase.Comment: 7 pages, 6 figures. Presented at Lattice 2017, the 35th International Symposium on Lattice Field Theory, Granada, Spain, 18-24 June 201

Comparison of ease of insertion, visibility of strings and continuation rate of post-partum intrauterine copper device insertion by long inserter versus with the help of Kelly’s forceps

Background: The objective of the study was to compare ease of insertion, visibility of strings and continuation rate of post-partum intrauterine copper devices (PPIUCD) insertion by long inserter versus with the help of Kelly’s forceps.Methods: 100 women were enrolled in our study which was conducted in department of obstetrics and gynecology, Subharti medical college and Chattrapati Shivaji Subharti hospital (CSSH), Meerut over a period of 2 years between November 2018 and August 2020. In study comparison was done on insertion technique of PPIUCD.Results: High fundal placement was achieved with long inserter. There was no perforation and decreased infection rate among the users with no increase in incidence of side effects and expulsion. Among 50 insertion, 1 woman (2%) had partial expulsion, 2 women (4%) had complete expulsion and 1 woman (2%) got PPIUCD removed on request. Providers reported 100% easier technique. 96% satisfaction among the users.Conclusions: The dedicated long inserter PPIUCD was found to be safe, with high acceptability among the participants and providers. Study revealed the reduced risk of infection and expulsion, providers also reported increased convenience in insertion compared to standard PPIUCD insertion techniques

USG guided femoral nerve block vs fascia iliaca compartment block as post-operative analgesia in hip fracture patients

Background: Adequate postoperative analgesia facilitates early mobilization which is important to reduce postoperative morbidity. Here, we intended to compare the efficacy of two different nerve blocks for postoperative pain relief in fractured neck of femur patients.Methods: One hundred and five patients posted either for dynamic hip screw or proximal femoral nail implantation under spinal anaesthesia were randomly allocated to three groups. At the end of surgery, group 1 received femoral nerve block (FNB) and group 2 received fascia iliaca compartment block (FICB) for postoperative pain relief. These blocks were ultrasound guided. Group 3 received no block and acted as control. Patients’ pain was evaluated by Visual Analogue Scale (VAS) both at rest and at passive elevation of leg. Rescue analgesia was given when VAS score exceeded 3. Heart rate, mean arterial blood pressure, respiratory rate and total analgesic consumption in first 24 hours were also recorded.Results: Groups 1 and 2 had similar duration of analgesia of around 8 hours (P value = 0.727). Analgesic consumption in both these groups were similar (P value = 0.648). These groups had less pain, less analgesic requirement and more stable haemodynamics as compared to group 3. No adverse effect was seen due to application of block.Conclusions: FICB can be an effective alternative to femoral nerve block, because of its relative simplicity in technique and less invasiveness. Hence FICB holds considerable promise as an effective postoperative analgesia

MANAGEMENT OF PSORIASIS THROUGH AYURVEDA- A CASE STUDY

Psoriasis is one of the most common dermatologic diseases, affecting up to 1% of the world's population. It is a chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules and rounded plaques, covered by silvery micaceous scale. It has poorly understood etiology and presence of 50% positive family history. Drugs used now a day are basically immunosuppressive which have severe side effects along with remission of disease as well therefore holistic approach of Ayurveda can be a better approach to such disease. Psoriasis due to its different manifestation in different types can be correlated to different types of Kustha mentioned in Ayurveda. So the case being presented here is a male patient with red demarcated patches with severe itching in armpits, groin and nipple.Material and method: The patient was administered with Virechana with Trivritaavaleha followed by Shamana drugs.Results: After Virechana there was the complete improvement in itching and redness of patches was reduced to some extent but after using Shamana drugs there was moderate reduction in all the symptoms along with mild remission.Conclusion: There is need to develop a management for psoriasis which can give benefit on a long run without any adverse effects so, Ayurvedic system of medicine could be answer to this question

Peri-Operative Cataract Surgery Complications associated with Hepatitis C: an observational study

 Introduction: Small Incision Cataract surgery (SICS) is one of the most commonly performed surgery and the Hepatitis C virus infection in the country like ours is an upcoming health hazard. Undiagnosed asymptomatic HCV sero-positive cases outnumber the diagnosed cases. Hypocoagulability because of hepatitis, can cause detrimental effect on cataract surgery.  Objective: To analyze the cataract surgery complications in HCV infected cases. Methods: This was a prospective, observational study conducted in the department of Ophthalmology of Muzaffarnagar Medical College, Uttar Pradesh from January 2019 to January 2020. After taking permission from the ethical committee and informed-written consent from the patients, total 200 eyes of 158 patients having (116 unilateral and 42 bilateral) cataract and incidentally diagnosed positive for HCV infection were enrolled in the study.Results: Out of 200 eyes, 48 eyes had no complications and 152 (76%) eyes had one or more complications like intra-operative bleed (68%), difficulty in wound closure (19.5%), post-operative AC reaction (61.5%), delayed healing (49%), hyphema (48%), leaky wound (37%) and keratitis (34%).Conclusion: Significant number of asymptomatic HCV sero-positive patients undergoing cataract surgery had peri-operative complications. It is recommended that pre-operative viral marker screening of all cataract patients should be done and measures to combat the difficulties during and after the surgery should be taken care of.&nbsp

A case report on serous cyst fibroadenoma of ovary

A 16-year-old unmarried female patient presented to the Subharti hospital with a lump in her abdomen that had been there for one year. For the previous two months, there had been abdominal pain. Constipation, intermittent fever, and vomiting were all present. A mass of around 25×25 cm (approximately) was found on per-abdominal examination, which was firm in consistency, non-tender, afebrile to touch with smooth borders, and restricted mobility. On the basis of the above mentioned examination and investigation, a diagnosis of ovarian cyst with typhoid immunoglobulin G (IgG) and immunoglobulin M (IgM) positive, dengue IgG with hepatitis B surface antigen (HbsAg) positive was made

Phylogeography of mtDNA haplogroup R7 in the Indian peninsula.

BACKGROUND: Human genetic diversity observed in Indian subcontinent is second only to that of Africa. This implies an early settlement and demographic growth soon after the first 'Out-of-Africa' dispersal of anatomically modern humans in Late Pleistocene. In contrast to this perspective, linguistic diversity in India has been thought to derive from more recent population movements and episodes of contact. With the exception of Dravidian, which origin and relatedness to other language phyla is obscure, all the language families in India can be linked to language families spoken in different regions of Eurasia. Mitochondrial DNA and Y chromosome evidence has supported largely local evolution of the genetic lineages of the majority of Dravidian and Indo-European speaking populations, but there is no consensus yet on the question of whether the Munda (Austro-Asiatic) speaking populations originated in India or derive from a relatively recent migration from further East. RESULTS: Here, we report the analysis of 35 novel complete mtDNA sequences from India which refine the structure of Indian-specific varieties of haplogroup R. Detailed analysis of haplogroup R7, coupled with a survey of approximately 12,000 mtDNAs from caste and tribal groups over the entire Indian subcontinent, reveals that one of its more recently derived branches (R7a1), is particularly frequent among Munda-speaking tribal groups. This branch is nested within diverse R7 lineages found among Dravidian and Indo-European speakers of India. We have inferred from this that a subset of Munda-speaking groups have acquired R7 relatively recently. Furthermore, we find that the distribution of R7a1 within the Munda-speakers is largely restricted to one of the sub-branches (Kherwari) of northern Munda languages. This evidence does not support the hypothesis that the Austro-Asiatic speakers are the primary source of the R7 variation. Statistical analyses suggest a significant correlation between genetic variation and geography, rather than between genes and languages. CONCLUSION: Our high-resolution phylogeographic study, involving diverse linguistic groups in India, suggests that the high frequency of mtDNA haplogroup R7 among Munda speaking populations of India can be explained best by gene flow from linguistically different populations of Indian subcontinent. The conclusion is based on the observation that among Indo-Europeans, and particularly in Dravidians, the haplogroup is, despite its lower frequency, phylogenetically more divergent, while among the Munda speakers only one sub-clade of R7, i.e. R7a1, can be observed. It is noteworthy that though R7 is autochthonous to India, and arises from the root of hg R, its distribution and phylogeography in India is not uniform. This suggests the more ancient establishment of an autochthonous matrilineal genetic structure, and that isolation in the Pleistocene, lineage loss through drift, and endogamy of prehistoric and historic groups have greatly inhibited genetic homogenization and geographical uniformity.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are