Application of Neural-Fuzzy System in Twin-Turbo Hydraulic Torque Converter's Performance Testing

AbstractTwin-turbo hydraulic torque converter's performance testing is very important in the product's development and production. According to the needs of data processing and analysis in performance testing, A neural-fuzzy algorithm was used to analyze the test data in this paper. It can improve computing speed and programming capability, decrease artificial involved times, realize the data analysis processing's automation. The application shows that the digital information's relationship can be expressed very well by this method. At the same time, this method has high degree of accuracy and quick speed on data recognition and can satisfy the requirement of designing

Effective and efficient midlevel visual elements-oriented land-use classification using VHR remote sensing images

Land-use classification using remote sensing images covers a wide range of applications. With more detailed spatial and textural information provided in very high resolution (VHR) remote sensing images, a greater range of objects and spatial patterns can be observed than ever before. This offers us a new opportunity for advancing the performance of land-use classification. In this paper, we first introduce an effective midlevel visual elements-oriented land-use classification method based on “partlets,” which are a library of pretrained part detectors used for midlevel visual elements discovery. Taking advantage of midlevel visual elements rather than low-level image features, a partlets-based method represents images by computing their responses to a large number of part detectors. As the number of part detectors grows, a main obstacle to the broader application of this method is its computational cost. To address this problem, we next propose a novel framework to train coarse-to-fine shared intermediate representations, which are termed “sparselets,” from a large number of pretrained part detectors. This is achieved by building a single-hidden-layer autoencoder and a single-hidden-layer neural network with an L0-norm sparsity constraint, respectively. Comprehensive evaluations on a publicly available 21-class VHR land-use data set and comparisons with state-of-the-art approaches demonstrate the effectiveness and superiority of this paper

17β-Estradiol Enhances Breast Cancer Cell Motility and Invasion via Extra-Nuclear Activation of Actin-Binding Protein Ezrin

Estrogen promotes breast cancer metastasis. However, the detailed mechanism remains largely unknown. The actin binding protein ezrin is a key component in tumor metastasis and its over-expression is positively correlated to the poor outcome of breast cancer. In this study, we investigate the effects of 17β-estradiol (E2) on the activation of ezrin and its role in estrogen-dependent breast cancer cell movement. In T47-D breast cancer cells, E2 rapidly enhances ezrin phosphorylation at Thr567 in a time- and concentration-dependent manner. The signalling cascade implicated in this action involves estrogen receptor (ER) interaction with the non-receptor tyrosine kinase c-Src, which activates the phosphatidylinositol-3 kinase/Akt pathway and the small GTPase RhoA/Rho-associated kinase (ROCK-2) complex. E2 enhances the horizontal cell migration and invasion of T47-D breast cancer cells in three-dimensional matrices, which is reversed by transfection of cells with specific ezrin siRNAs. In conclusion, E2 promotes breast cancer cell movement and invasion by the activation of ezrin. These results provide novel insights into the effects of estrogen on breast cancer progression and highlight potential targets to treat endocrine-sensitive breast cancers

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Self-Image Congruence, Functional Congruence, and Mobile App Intention to Use

Although the research on the technology acceptance model (TAM) has received much attention, limited research has been done on the role of self-image congruence on the mobile application (app) intention to use. Therefore, leveraging the lens of the self-congruence theory, the primary objective of the present research is to examine the impact of self-image and functional congruence on the mobile app intention to use. We conduct a survey and collect 349 responses from Chinese smartphone users. The results of the current research reveal that self-image congruence is positively significantly related to mobile app intention to use. Also, our findings show that symbolic congruence is a vital determinant of the mobile app intention to use among Chinese smartphone users. Overall, the present study extends the understanding of TAM and concludes that symbolic congruence, such as functional attributes, is equally essential for technology intention to use. Moreover, this study extends the TAM and self-congruence theory literature by empirically investigating and validating the conceptual framework. The present study highlights the significance of self-image congruence to understand the user mobile app adoption behavior better. It provides important knowledge for the app developers, researchers, policymakers, and marketing managers of the famous social commerce and popular brand apps

Stability analysis of a nonlocal SIHRDP epidemic model with memory effects.

The prediction and control of COVID-19 is critical for ending this pandemic. In this paper, a nonlocal SIHRDP (S-susceptible class, I-infective class (infected but not hospitalized), H-hospitalized class, R-recovered class, D-death class and P-isolated class) epidemic model with long memory is proposed to describe the multi-wave peaks for the spread of COVID-19. Based on the basic reproduction number R0 , which is completely controlled by fractional order, the stability of the proposed system is studied. Furthermore, the numerical simulation is conducted to gauge the performance of the proposed model. The results on Hunan, China, reveal that R0<1 suggests that the disease-free equilibrium point is globally asymptotically stable. Likewise, the situation of the multi-peak case in China is presented, and it is clear that the nonlocal epidemic system has a superior fitting effect than the classical model. Finally an adaptive impulsive vaccination is introduced based on the proposed system. Then employing the real data of France, India, the USA and Argentina, parameters identification and short-term forecasts are carried out to verify the effectiveness of the proposed model in describing the case of multiple peaks. Moreover, the implementation of vaccine control is expected once the hospitalized population exceeds 20% of the total population. Numerical results of France, Indian, the USA and Argentina shed light on the varied effect of vaccine control in different countries. According to the vaccine control imposed on France, no obvious effect is observed even consider reducing human contact. As for India, although there will be a temporary increase in hospitalized admissions after execution of vaccination control, COVID-19 will eventually disappear. Results on the USA have seen most significant effect of vaccine control, the number of hospitalized individuals drops off and the disease is eventually eradicated. In contrast to the USA, vaccine control in Argentina has also been very effective, but COVID-19 cannot be completely eradicated