Public Library as a Social Interactive Space

This paper elaborates on the current condition of the public library, focusing on the one in Alor Gajah.  One of the main issues faced by the public library today is the lack of visitors.  Scholars suggest that it is crucial to integrate the users’ perspectives into the building design as the sense of attachment of the user to a place can greatly affect their attitude towards the spaces perceived.  The study aims to investigate the new approaches in the design of a library, to upgrade it as a social interactive space, particularly in Alor Gajah, Melaka.  

Impacts of anthropogenic heat on summertime rainfall in Beijing

Anthropogenic heat is an important component of the urban energy budgets that can affect land surface and atmospheric boundary layer processes. Representation of anthropogenic heat in numerical climate modeling systems is therefore important when simulating urban meteorology and climate and has the potential to improve weather forecasts, climate process studies, and energy demand analysis. Here, spatiotemporally dynamic anthropogenic heat data estimated by the Building Effects Parameterization and Building Energy Model (BEP-BEM) are incorporated into the Weather Research and Forecasting (WRF) Model system to investigate its impact on simulation of summertime rainfall in Beijing, China. Simulations of four local rainfall events with and without anthropogenic heat indicate that anthropogenic heat leads to increased rainfall over the urban area. For all four events, anthropogenic heat emission increases sensible heat flux, enhances mixing and turbulent energy transport, lifts PBL height, increases dry static energy, and destabilizes the atmosphere in urban areas through thermal perturbation and strong upward motion during the prestorm period, resulting in enhanced convergence during the major rainfall period. Intensified rainfall leads to greater atmospheric dry-down during the storm and a higher poststorm LCL

Cloning and analysis of a NBS-LRR disease resistance gene candidate PnAG1 from peanut ( Arachis hypogaea L.)

Background: Based on the conserved sequences of a known NBS resistance gene, a pair of degenerate primers was designed to amplify the NBS-LRR resistance gene from peanut using PCR and RACE methods. Results: Analyzing the amino acid sequence by BLAST on NCBI, which was deduced from the 1088bp-long gene named PnAG1-2, showed that it had a certain homology with some resistance proteins, among which Arachis cardenasii resistance protein gene had the highest homology (66%). Relative quantification PCR analysis indicated that PnAG1-2 gene expresses more in J11 (an A. flavus-resistant variety) than in JH1012 (an A. flavus-susceptible variety) when the harvest time was coming. Conclusions: In this study, the NBS-LRR resistance sequence was successfully cloned from peanut and prokaryotic expression was done on the gene, which provided a foundation for cultivating anti-A. flavus peanut varieties

Paralogues from the expanded Tlr11 gene family in mudskipper (Boleophthalmus pectinirostris) are under positive selection and respond differently to LPS/Poly(I:C) challenge

publishedVersio

Impact of Different Static Air-Gap Eccentricity Forms on Rotor UMP of Turbogenerator

Theoretical analysis and numerical FEM calculations, together with segmental experiment studies, are used to study the impact of the static air-gap eccentricity forms on the rotor unbalanced magnetic pull (UMP) of turbogenerator. The universal expression of the magnetic flux density under different forms of SAGE is firstly deduced, based on which the detailed UMP formulas for the normal condition and three SAGE cases are obtained, respectively. Then the exciting characteristics of the UMP for each SAGE form to generate vibrations are analyzed. Finally, numerical FEM calculations and segmental experiments are carried out to investigate the effect of SAGE forms on the rotor UMP, taking the SDF-9 type non-salient-pole fault simulating generator as the object. It is shown that, no matter what kind of SAGE occurs, amplitude increments at each even harmonic component of the UMP and the rotor vibration, especially the 2nd harmonic component, will be brought in. Meanwhile, the UMP keeps directing to the very position where the minimum radial air-gap is. Among the different SAGE forms, the rotor offset has the most sensitive effect on the rotor UMP and vibration, while the stator ellipse deformation has the weakest impact

The effects of low frequency electrical stimulation on satellite cell activity in rat skeletal muscle during hindlimb suspension

<p>Abstract</p> <p>Background</p> <p>The ability of skeletal muscle to grow and regenerate is dependent on resident stem cells called satellite cells. It has been shown that chronic hindlimb unloading downregulates the satellite cell activity. This study investigated the role of low-frequency electrical stimulation on satellite cell activity during a 28 d hindlimb suspension in rats.</p> <p>Results</p> <p>Mechanical unloading resulted in a 44% reduction in the myofiber cross-sectional area as well as a 29% and 34% reduction in the number of myonuclei and myonuclear domains, respectively, in the soleus muscles (<it>P </it>< 0.001 <it>vs </it>the weight-bearing control). The number of quiescent (M-cadherin⁺), proliferating (BrdU⁺and myoD⁺), and differentiated (myogenin⁺) satellite cells was also reduced by 48-57% compared to the weight-bearing animals (<it>P </it>< 0.01 for all). Daily application of electrical stimulation (2 × 3 h at a 20 Hz frequency) partially attenuated the reduction of the fiber cross-sectional area, satellite cell activity, and myonuclear domain (<it>P </it>< 0.05 for all). Extensor digitorum longus muscles were not significantly altered by hindlimb unloading.</p> <p>Conclusion</p> <p>This study shows that electrical stimulation partially attenuated the decrease in muscle size and satellite cells during hindlimb unloading. The causal relationship between satellite cell activation and electrical stimulation remain to be established.</p

Extracorporeal membrane oxygenation for neonatal congenital diaphragmatic hernia: The initial single-center experience in Taiwan

Background/Purpose Extracorporeal membrane oxygenation (ECMO) is a treatment option for stabilizing neonates with congenital diaphragmatic hernia (CDH) in a critical condition when standard therapy fails. However, the use of this approach in Taiwan has not been previously reported. Methods The charts of all neonates with CDH treated in our institute during the period 2007–2014 were reviewed. After 2010, patients who could not be stabilized with conventional treatment were candidates for ECMO. We compared the demographic data of patients with and without ECMO support. The clinical course and complications of ECMO were also reviewed. Results We identified 39 neonates with CDH with a median birth weight of 2696 g (range, 1526–3280 g). Seven (18%) of these patients required ECMO support. The APGAR score at 5 minutes differed significantly between the ECMO and non-ECMO groups. The survival rate was 84.6% (33/39) for all CDH patients and 57.1% (4/7) for the ECMO group. The total ECMO bypass times in the survivors was in the range of 5–36 days, whereas all nonsurvivors received ECMO for at least 36 days (mean duration, 68 days). Surgical bleeding occurred in four of seven patients in the ECMO group. Conclusion The introduction of ECMO rescued some CDH patients who could not have survived by conventional management. Prolonged (i.e., > 36 days) ECMO support had no benefit for survival

Scientific layout and integrative development of urban and rural health and family planning resources under the background of the new urbanization

新型城镇化是中国现代化的必由之路，是扩大内需、促进区域协调发展的重要抓手。新型城镇化建设客观上要求城乡卫生计生资源配置逐步破除城乡二元体制，科学布局，均衡发展。基于当前S省城乡卫生计生资源在整合方面的滞后性、配置方面的非均衡性、布局与发展方面的不适应性等问题，以及对S省城乡卫生计生资源整合的挑战与机遇分析，本研究提出在新型城镇化进程中应该正确认识城乡卫生计生资源整合的必要性和发展的持续性，厘清整合后卫生和计生部门之间的关系，实现S省城乡卫生计生资源科学布局与融合发展，保障城乡居民的医疗卫生服务需求，推进新型城镇化建设的质量和速度。New type of urbanization is the only way for China's modernization and the key to expanding domestic demand and promoting regional coordinated development. The new urbanization objectively requires the urban and rural health planning resources to gradually get rid of the urban-rural dual structure, scientific layout, balanced development. Based on the hysteretic integration, imbalance allocation, and the analysis of health family and planning resources integration between urban and rural areas in our province, this paper argues that in the new urbanization, we should correctly understand the necessity of health and family planning resources integration and the  sustainability of development. In addition, it is very important to clarify the relationship between health and family planning department after integration. Only in this way, our province can realize the scientific layout and integrative development of urban and rural health and family planning resources, ensure the health service demand of urban and rural residents, and promote the quality and speed of the new type of urbanization construction

Impact of Radial Air-Gap Eccentricity on Stator End Winding Vibration Characteristics in DFIG

In this paper, qualitative theoretical derivations, finite element analysis (FEA) and experiments are used to investigate the electromagnetic force (EF) and vibration characteristics of end windings. In contrast to previous studies, this study focuses not only on end winding EF/vibration under normal and radial static air gap eccentricity (RSAGE) conditions, but also for the cases of radial dynamic air gap eccentricity (RDAGE) and radial dynamic static hybrid air gap eccentricity (RHAGE). Firstly, the magnetic flux density (MFD) is derived for normal and radial air gap eccentricity (RAGE) faults, and detailed EF expressions are obtained before and after the RAGE fault. The finite element analysis (FEA) and experimental studies were performed on a four-pole DFIG at a speed of 1500 rpm to verify the proposed theoretical analysis. It is shown that RSAGE only enlarges the EF/end winding vibration and does not introduce new frequency components. RDAGE not only increases EF/end winding vibration but also introduces new frequency components. RHAGE can be seen as a superimposed effect of RSAGE and RDAGE