Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition

The present report describes a microwave assisted convenient and efficient protocol for the synthesis of new 6-(4-substituted-phenyl)-3-methylimidazo[2,1-b]thiazole-2-carbohydra- zide derivatives. The current method holds a tag of green synthesis by virtue of catalyst and solvent free media. Moreover, the procedure offers excellent yield and purity of the products under mild condition compared with conventional method

Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition

The present report describes a microwave assisted convenient and efficient protocol for the synthesis of new 6-(4-substituted-phenyl)-3-methylimidazo[2,1-b]thiazole-2-carbohydra- zide derivatives. The current method holds a tag of green synthesis by virtue of catalyst and solvent free media. Moreover, the procedure offers excellent yield and purity of the products under mild condition compared with conventional method

A rapid, mild, and efficient method for C-5 iodination/thiocyanation of 2-aminothiazoles

<p>An efficient, green, rapid multitasking protocol for the selective C-5 substitution of 2-aminothiazole using iodic acid and aqueous PEG-400 was developed. The method found suitable for C-5 substitution i.e. iodination and thiocyanation of 2-amino thiazole using iodine and ammonium thiocyanate respectively. Iodic acid was found to be a good oxidant and aqueous PEG-400 as green reaction solvent.</p