8 research outputs found
Vibrations of perforated plate in flow
Object and purpose of research. A study of inception conditions for hydroelastic self-induced vibrations of perforated plate in slip flow. Materials and methods. Vibration spectra measurements of plate in flow. Analysis of physical nature of vibration frequency spectra maximums. Main results. Inception conditions for hydroelastic self-induced vibrations of perforated plate in slip flow were determined. Conclusion. Proposals for prevention the inception of hydroelastic self-induced vibrations in ship structures including perforated plates in water slip flow were formulated
Simulated B-cells Rep-Seq datasets (called SIMULATED) from "Reconstructing antibody repertoires from error-prone immunosequencing datasets" paper
Simulated test datasets used for benchmarking of immunorepertoire construction tool
Verification of the Numerical Model in the Problem of Studying Directional Characteristics of Sound Radiation from Inhomogeneous Shells
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are an important class of natural products that contain antibiotics and a variety of other bioactive compounds. The existing methods for discovery of RiPPs by combining genome mining and computational mass spectrometry are limited to discovering specific classes of RiPPs from small datasets, and these methods fail to handle unknown post-translational modifications. Here, we present MetaMiner, a software tool for addressing these challenges that is compatible with large-scale screening platforms for natural product discovery. After searching millions of spectra in the Global Natural Products Social (GNPS) molecular networking infrastructure against just eight genomic and metagenomic datasets, MetaMiner discovered 31 known and seven unknown RiPPs from diverse microbial communities, including human microbiome and lichen microbiome, and microorganisms isolated from the International Space Station