Intravenous Cyclophosphamide Therapy in Adults with Henoch-Schönlein Purpura

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Observation of Topologically Stable 2D Skyrmions in an Antiferromagnetic Spinor Bose-Einstein Condensate

We present the creation and time evolution of two-dimensional Skyrmion excitations in an antiferromagnetic spinor Bose-Einstein condensate. Using a spin rotation method, the Skyrmion spin textures were imprinted on a sodium condensate in a polar phase, where the two-dimensional Skyrmion is topologically protected. The Skyrmion was observed to be stable on a short time scale of a few tens of ms but to have dynamical instability to deform its shape and eventually decay to a uniform spin texture. The deformed spin textures reveal that the decay dynamics involves breaking the polar phase inside the condensate without having topological charge density flow through the boundary of the finite-sized sample. We discuss the possible formation of half-quantum vortices in the deformation process.Comment: 5 pages, 5 figure

Bivariate Beta-LSTM

Long Short-Term Memory (LSTM) infers the long term dependency through a cell state maintained by the input and the forget gate structures, which models a gate output as a value in [0,1] through a sigmoid function. However, due to the graduality of the sigmoid function, the sigmoid gate is not flexible in representing multi-modality or skewness. Besides, the previous models lack modeling on the correlation between the gates, which would be a new method to adopt inductive bias for a relationship between previous and current input. This paper proposes a new gate structure with the bivariate Beta distribution. The proposed gate structure enables probabilistic modeling on the gates within the LSTM cell so that the modelers can customize the cell state flow with priors and distributions. Moreover, we theoretically show the higher upper bound of the gradient compared to the sigmoid function, and we empirically observed that the bivariate Beta distribution gate structure provides higher gradient values in training. We demonstrate the effectiveness of bivariate Beta gate structure on the sentence classification, image classification, polyphonic music modeling, and image caption generation.Comment: AAAI 202

Complications of nephrotic syndrome

Nephrotic syndrome (NS) is one of the most common glomerular diseases that affect children. Renal histology reveals the presence of minimal change nephrotic syndrome (MCNS) in more than 80% of these patients. Most patients with MCNS have favorable outcomes without complications. However, a few of these children have lesions of focal segmental glomerulosclerosis, suffer from severe and prolonged proteinuria, and are at high risk for complications. Complications of NS are divided into two categories: disease-associated and drug-related complications. Disease-associated complications include infections (e.g., peritonitis, sepsis, cellulitis, and chicken pox), thromboembolism (e.g., venous thromboembolism and pulmonary embolism), hypovolemic crisis (e.g., abdominal pain, tachycardia, and hypotension), cardiovascular problems (e.g., hyperlipidemia), acute renal failure, anemia, and others (e.g., hypothyroidism, hypocalcemia, bone disease, and intussusception). The main pathomechanism of disease-associated complications originates from the large loss of plasma proteins in the urine of nephrotic children. The majority of children with MCNS who respond to treatment with corticosteroids or cytotoxic agents have smaller and milder complications than those with steroid-resistant NS. Corticosteroids, alkylating agents, cyclosporin A, and mycophenolate mofetil have often been used to treat NS, and these drugs have treatment-related complications. Early detection and appropriate treatment of these complications will improve outcomes for patients with NS

Evidence for a preformed Cooper pair model in the pseudogap spectra of a Ca10(Pt4As8)(Fe2As2)5 single crystal with a nodal superconducting gap

For high-Tc superconductors, clarifying the role and origin of the pseudogap is essential for understanding the pairing mechanism. Among the various models describing the pseudogap, the preformed Cooper pair model is a potential candidate. Therefore, we present experimental evidence for the preformed Cooper pair model by studying the pseudogap spectrum observed in the optical conductivity of a Ca10(Pt4As8)(Fe2As2)5 (Tc = 34.6 K) single crystal. We observed a clear pseudogap structure in the optical conductivity and observed its temperature dependence. In the superconducting (SC) state, one SC gap with a gap size of {\Delta} = 26 cm-1, a scattering rate of 1/{\tau} = 360 cm-1 and a low-frequency extra Drude component were observed. Spectral weight analysis revealed that the SC gap and pseudogap are formed from the same Drude band. This means that the pseudogap is a gap structure observed as a result of a continuous temperature evolution of the SC gap observed below Tc. This provides clear experimental evidence for the preformed Cooper pair model.Comment: 15 pages, 4 figure

Predicting Disease Activity in Systemic Vasculitides: On the Hunt for Potential Candidates

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Relaxation of superfluid turbulence in highly oblate Bose-Einstein condensates

We investigate thermal relaxation of superfluid turbulence in a highly oblate Bose-Einstein condensate. We generate turbulent flow in the condensate by sweeping the center region of the condensate with a repulsive optical potential. The turbulent condensate shows a spatially disordered distribution of quantized vortices and the vortex number of the condensate exhibits nonexponential decay behavior which we attribute to the vortex pair annihilation. The vortex-antivortex collisions in the condensate are identified with crescent-shaped, coalesced vortex cores. We observe that the nonexponential decay of the vortex number is quantitatively well described by a rate equation consisting of one-body and two-body decay terms. In our measurement, we find that the local two-body decay rate is closely proportional to $T^2/\mu$, where $T$ is the temperature and $\mu$ is the chemical potential.Comment: 7 pages, 9 figure