Throughput Maximization Leveraging Just-Enough SNR Margin and Channel Spacing Optimization

Flexible optical network is a promising technology to accommodate high-capacity demands in next-generation networks. To ensure uninterrupted communication, existing lightpath provisioning schemes are mainly done with the assumption of worst-case resource under-provisioning and fixed channel spacing, which preserves an excessive signal-to-noise ratio (SNR) margin. However, under a resource over-provisioning scenario, the excessive SNR margin restricts the transmission bit-rate or transmission reach, leading to physical layer resource waste and stranded transmission capacity. To tackle this challenging problem, we leverage an iterative feedback tuning algorithm to provide a just-enough SNR margin, so as to maximize the network throughput. Specifically, the proposed algorithm is implemented in three steps. First, starting from the high SNR margin setup, we establish an integer linear programming model as well as a heuristic algorithm to maximize the network throughput by solving the problem of routing, modulation format, forward error correction, baud-rate selection, and spectrum assignment. Second, we optimize the channel spacing of the lightpaths obtained from the previous step, thereby increasing the available physical layer resources. Finally, we iteratively reduce the SNR margin of each lightpath until the network throughput cannot be increased. Through numerical simulations, we confirm the throughput improvement in different networks and with different baud-rates. In particular, we find that our algorithm enables over 20\% relative gain when network resource is over-provisioned, compared to the traditional method preserving an excessive SNR margin.Comment: submitted to IEEE JLT, Jul. 17th, 2021. 14 pages, 8 figure

On 4n4n-dimensional neither pointed nor semisimple Hopf algebras and the associated weak Hopf algebras

For a class of neither pointed nor semisimple Hopf algebras $H_{4n}$ of dimension $4n$, it is shown that they are quasi-triangular, which universal $R$-matrices are described. The corresponding weak Hopf algebras $\mathfrak{w}H_{4n}$ and their representations are constructed. Finally, their duality and their Green rings are established by generators and relations explicitly. It turns out that the Green rings of the associated weak Hopf algebras are not commutative even if the Green rings of $H_{4n}$ are commutative.Comment: 18 page

Mapping the potential distribution of high artemisinin-yielding Artemisia annua L. (Qinghao) in China with a geographic information system

<p>Abstract</p> <p>Background</p> <p><it>Artemisia annua </it>L. is an important source for artemisinin, a potent drug for treating malaria. This study aims to map and predict the potential geographic distribution of <it>A. annua </it>L. in China.</p> <p>Methods</p> <p>The Geographic Information System for traditional Chinese medicine (TCM-GIS) was developed and used to map the potential geographic distribution of <it>A. annua </it>L.</p> <p>Results</p> <p>Climatic, edaphic and topographic characteristics of <it>A. annua </it>L. microhabitats in Youyang County were mapped to find distribution patterns. The maps identified that certain habitats in the Chongqing region and some potential regions, especially in Guizhou Province, possess similarity indices of ≥98%. In particular, high quality microhabitats <it>A. annua </it>L. were found in the Wuling mountains region.</p> <p>Conclusion</p> <p>The present study demonstrates a GIS approach to predict potential habitats for <it>A. annua </it>L. TCM-GIS is a powerful tool for assessing bioclimatic suitability for medicinal plants.</p

Throughput Maximization in Multi-Band Optical Networks with Column Generation

Multi-band transmission is a promising technical direction for spectrum and capacity expansion of existing optical networks. Due to the increase in the number of usable wavelengths in multi-band optical networks, the complexity of resource allocation problems becomes a major concern. Moreover, the transmission performance, spectrum width, and cost constraint across optical bands may be heterogeneous. Assuming a worst-case transmission margin in U, L, and C-bands, this paper investigates the problem of throughput maximization in multi-band optical networks, including the optimization of route, wavelength, and band assignment. We propose a low-complexity decomposition approach based on Column Generation (CG) to address the scalability issue faced by traditional methodologies. We numerically compare the results obtained by our CG-based approach to an integer linear programming model, confirming the near-optimal network throughput. Our results also demonstrate the scalability of the CG-based approach when the number of wavelengths increases, with the computation time in the magnitude order of 10 s for cases varying from 75 to 1200 wavelength channels per link in a 14-node network.Comment: 6 pages, 4 figures, submitted to IEEE International Conference on Communications 2024 (ICC2024). (Note on arXiv: for beginners in the area of column generation, please refer to the example computation in the file . I have uploaded it to this arXiv project along with other source files.

Gut microbiota and immune mediation: a Mendelian randomization study on granulomatosis with polyangiitis

BackgroundThe gut microbiota plays a pivotal role in influencing various health outcomes, including immune-mediated conditions. Granulomatosis with Polyangiitis (GPA) is one such condition, and its potential associations with gut microbiota remain underexplored.MethodUsing a two-sample Mendelian randomization approach, we investigated the causal links between gut microbiota and GPA. We sourced our data from multiple cohorts and consortiums, including the MiBioGen consortium. Our study design incorporated both direct associations and mediation effects of immune traits on the relationship between gut microbiota and GPA.ResultsOur analysis revealed significant associations between 1 phylum, 1 family 9 genus microbiota taxa and GPA. Furthermore, we identified several immune cell traits that mediated the effects of gut microbiota on GPA. For instance, the family Defluviitaleaceae and genus Defluviitaleaceae UCG011 influenced GPA through CD11c in granulocytes. The mediation effect proportions further elucidated the complex dynamics between gut microbiota exposures, immune markers, and their combined influence on GPA.ConclusionOur findings underscore the intricate relationship between gut microbiota, immune markers, and GPA. The identified associations and mediation effects provide valuable insights into the potential therapeutic avenues targeting gut microbiota to manage GPA

Integrated metagenomics and metabolomics analysis reveals changes in the microbiome and metabolites in the rhizosphere soil of Fritillaria unibracteata

Fritillaria unibracteata (FU) is a renowned herb in China that requires strict growth conditions in its cultivation process. During this process, the soil microorganisms and their metabolites may directly affect the growth and development of FU, for example, the pathogen infection and sipeimine production. However, few systematic studies have reported the changes in the microbiome and metabolites during FU cultivation thus far. In this work, we simultaneously used metagenomics and metabolomics technology to monitor the changes in microbial communities and metabolites in the rhizosphere of FU during its cultivation for one, two, and three years. Moreover, the interaction between microorganisms and metabolites was investigated by co-occurrence network analysis. The results showed that the microbial composition between the three cultivation-year groups was significantly different (2020-2022). The dominant genera changed from Pseudomonas and Botrytis in CC1 to Mycolicibacterium and Pseudogymnoascus in CC3. The relative abundances of beneficial microorganisms decreased, while the relative abundances of harmful microorganisms showed an increasing trend. The metabolomics results showed that significant changes of the of metabolite composition were observed in the rhizosphere soil, and the relative abundances of some beneficial metabolites showed a decreasing trend. In this study, we discussed the changes in the microbiome and metabolites during the three-year cultivation of FU and revealed the relationship between microorganisms and metabolites. This work provides a reference for the efficient and sustainable cultivation of FU