Pentecostal Women and Religious Reformation in the Progressive Era: The Political Novelty of Women’s Religious and Organizational Leadership

The Progressive Era in America from 1870 to 1920 introduced unprecedented change in the way Americans lived, worked, and thought about themselves in relation to the rest of the world. New platforms of charitable benevolence, religious activism, and legislative reform were enacted to meet the changed demographic landscape initiated by waves of new immigration from Europe. The tenor of religious worship shifted in mainstream and evangelical churches to reflect not only new ways of response to these changes, but new ideas of women as authoritative leaders in secular and religious institutions. Charismatic evangelical women influenced by an era of change worked to establish autonomous ministries unbeholden to clergymen who declined to accept their scriptural authority to preach or occupy the pulpit. Women who identified within Holiness and Pentecostal traditions were no longer content to preach from street-corners or rented meeting rooms. Instead, women who considered themselves prophets and preachers established ministries that supported their initiatives of religious reform and advancement of women

Women, Feminism, and Aging in Appalachia

Aging has become a problem for men and women in Western societies where youth is touted and revered as a standard of success by which individual value is measured and esteemed. Older women in particular find that as they age they face discrimination in the form of ageism and social diminution. The purpose of the study is to remedy a lack of scholarship on aging in Appalachia and to establish a precedent for future studies. A liberal, feminist approach is used to analyze the results of recorded interviews and to interpret transcripts of relevant data. The results of the analysis are mixed owing to the heterogeneity of the women interviewed and the differences in personal circumstances, socioeconomic status, and levels of education that influence their perceptions. Limitations of the study include: the size of the sample, and a lack of ethnic diversity

Recasting the White Stereotype of Southern Appalachia: Contribution to Culture and Community by Black Appalachian Women

The myth and image of Southern Appalachia spun by local color writers of the early nineteenth century and, later, by local elites in privileged positions of power have long cast the historiography of the region in tones of Caucasian lineage and remediation. The production of culture, contribution to community, and service to church and, family long considered to be the domain of women has predominantly been viewed from the privilege of a white perspective. Prescriptive definitions of a monochromatic culture in the Uplands of Southern Appalachia has written out the cultural contribution of diverse ethnicities who continue to call the region home. The purpose of this study is to illuminate the ways in which women of color and diversity contribute to the production of culture through service to their communities, volunteer outreach, and service in the church and, as models of core Appalachian values for their families

Linguistic Features of Metaphor, Metonymy and Narrative Gap in “The Yellow Wallpaper:” A Literary Analysis

In 1890, Charlotte Perkins Gilman wrote a piece of fiction that reflected her personal experience for treatment of nervous exhaustion. The story she developed created controversy and comment after it was published and, years later, agitation among feminists who found allegories of truth in its narrative. This thesis explores the use of linguistic features employed by Gilman to establish cognitive connections between physical structures and social institutions, such as marriage and domesticity, that confine women within contractual obligations. Gilman’s use of extended metaphor challenges conventional conceptions of the home, inanimate objects, and institutional authority and her use of metonymy extrapolates examples from the particular to a wider review. The main findings of this inquiry reveal feminist opposition to women’s subjugated status in the marital relationship and to established hierarchies of male control. The literary analysis exposes the efficacy of narrative gap and textual silences in provoking the reader’s participation

The Effects Orthostatic Hypotension has on Falls: A study done in San Francisco with the Patient Population of the Veterans Affairs Hospital

The Effects Orthostatic Hypotension has on Falls: A Study Done in San Francisco Represented Population of the Veterans Affairs Hoapital The global AIM of this project is to Identify patients that are at risk for Orthostatic Hypotension (OH) with in the first 24 hours of addmission. It was identified that 50% of the falls over the last 4 quarters at the VA were OH related. The patients were not identified as a fall risk and over half of them had fallen multiple times. After performing a nursing survey online, a SWOT analysis, and a Root Cause Analysis using a fishbone diagram, The problem was identified as a gap in knowledge for the assessment of OH and poor implementation and standardization of the current fall program. The 124 bed unit of 2 B South is a Telemetry/Seizure unit that has over-flow from TCU. The patients are all Veteran’s, many who suffer from multiple co-morbidities, including psychiatric conditions and Post Traumatic Stress Disorder (PTSD). As the Clinical Nurse Leader (CNL) I will build and strengthen this project using two essential competencies. The first #3 Quality Improvement and Safety as this is the AIM of the project, to reduce falls. The second is #7 Interprofessional Collaboration for Improving Patient and Population Health Outcomes, through working with the medical staff on the unit we will build a strong team to enhance the quality and satisfaction of the patient. Evaluation of the OH patient at risk for falls, as defined by the Merck Manual, will be assessed following the guidelines of the Morse Fall Scale (MFS). 3 cycles of PDSA were ran over a weeks time to gain more specific information of gaps in knowledge and program process. I used Lewin’s Change Theory and Kotter’s Eight-Step Process for Leading Change. I selected two theories to guide me due to the staffs resistence to change, this has been a strong barrier dueing my rotation. The nursing surveys were done through an online questionaire to allow privacy and honest answers, I often made rounds on the unit meeting independantly with staff as well as visual assessments. Through the use of Evidence-based data, the current falls program was updated to incorporate OH patients. I have designed a patient pamphlet to help the nurses teach patients about OH and how it relates to falls. The project met or exceded the goal of reducing falls by 35% and repeat falls by 50%. The project started working with pharmacy and IT to change the charting process and identify patients that are on medications that could cause OH. These changes will not be in effect due to the projects length of 3.5 months, but the CNL preceptor will continue the project with the appointed Fall Champions. Education to the nurses was delivered by a projection power point on the wall once a month for 15 minutes. As the knowledge grew, the nurse became more confident and change started to take place. By mid November the staff, at 87%, had almost reach the 24 hour OH assessment goal of 95%. We celebrated small wins as a team with bagels or special treats. The nurse manager was able to get one paid day off for each of the Champion, with the restriction that each month they be reassessed for participation. My biggest surprise implementing this project was that this unit had just started hourly rounding and they were not doing post fall huddles. We did start PFH with this project as it is the best way to dissimenate information. It is proven research PFH reduce fall rates. Pre fall project the fall rate in July was 7 with 4 reoccuring falls at the end of the project the October fall rate was 2 with no reoccuring falls

Review for the generalist: evaluation of anterior knee pain

Anterior knee pain is common in children and adolescents. Evaluation and management is challenging and requires a thorough history and physical exam, and understanding of the pediatric skeleton. This article will review common causes of chronic anterior knee pain in the pediatric population with a focus on patellofemoral pain

Identification and characterization of a novel non-structural protein of bluetongue virus

Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins. The non-structural proteins (NS1, NS2, NS3/NS3a) play different key roles during the viral replication cycle. In this study we show that BTV expresses a fourth non-structural protein (that we designated NS4) encoded by an open reading frame in segment 9 overlapping the open reading frame encoding VP6. NS4 is 77–79 amino acid residues in length and highly conserved among several BTV serotypes/strains. NS4 was expressed early post-infection and localized in the nucleoli of BTV infected cells. By reverse genetics, we showed that NS4 is dispensable for BTV replication in vitro, both in mammalian and insect cells, and does not affect viral virulence in murine models of bluetongue infection. Interestingly, NS4 conferred a replication advantage to BTV-8, but not to BTV-1, in cells in an interferon (IFN)-induced antiviral state. However, the BTV-1 NS4 conferred a replication advantage both to a BTV-8 reassortant containing the entire segment 9 of BTV-1 and to a BTV-8 mutant with the NS4 identical to the homologous BTV-1 protein. Collectively, this study suggests that NS4 plays an important role in virus-host interaction and is one of the mechanisms played, at least by BTV-8, to counteract the antiviral response of the host. In addition, the distinct nucleolar localization of NS4, being expressed by a virus that replicates exclusively in the cytoplasm, offers new avenues to investigate the multiple roles played by the nucleolus in the biology of the cell

Optimal Conservation of Migratory Species

Background. Migratory animals comprise a significant portion of biodiversity worldwide with annual investment for their conservation exceeding several billion dollars. Designing effective conservation plans presents enormous challenges. Migratory species are influenced by multiple events across land and sea-regions that are often separated by thousands of kilometres and span international borders. To date, conservation strategies for migratory species fail to take into account how migratory animals are spatially connected between different periods of the annual cycle (i.e. migratory connectivity) bringing into question the utility and efficiency of current conservation efforts. Methodology/Principal Findings. Here, we report the first framework for determining an optimal conservation strategy for a migratory species. Employing a decision theoretic approach using dynamic optimization, we address the problem of how to allocate resources for habitat conservation for a Neotropical-Nearctic migratory bird, the American redstart Setophaga ruticilla, whose winter habitat is under threat. Our first conservation strategy used the acquisition of winter habitat based on land cost, relative bird density, and the rate of habitat loss to maximize the abundance of birds on the wintering grounds. Our second strategy maximized bird abundance across the entire range of the species by adding the constraint of maintaining a minimum percentage of birds within each breeding region in North America using information on migratory connectivity as estimated from stable-hydrogen isotopes in feathers. We show that failure to take into account migratory connectivity may doom some regional populations to extinction, whereas including information on migratory connectivity results in the protection of the species across its entire range. Conclusions/Significance. We demonstrate that conservation strategies for migratory animals depend critically upon two factors: knowledge of migratory connectivity and the correct statement of the conservation problem. Our framework can be used to identify efficient conservation strategies for migratory taxa worldwide, including insects, birds, mammals, and marine organisms

Prevalence and sociodemographic correlates of stunting, underweight, and overweight among Palestinian school adolescents (13-15 years) in two major governorates in the West Bank

<p>Abstract</p> <p>Background</p> <p>There is little information about height and weight status of Palestinian adolescents. The objective of this paper was to assess the prevalence of stunting, underweight, and overweight/obesity among Palestinian school adolescents (13-15 years) and associated sociodemographic factors in 2 major governorates in the West Bank.</p> <p>Methods</p> <p>A Cross-sectional survey was conducted in 2005 comprising 1942 students in 65 schools in Ramallah and Hebron governorates. Data was collected through self-administered questionnaires from students and parents. Weights and heights were measured. Overweight and obesity were assessed using the 2000 Centers for Disease Control and Prevention (CDC) reference and the International Obesity Task Force (IOTF) criteria. Stunting and underweight were assessed using the 2000 CDC reference.</p> <p>Results</p> <p>Overweight/obesity was more prevalent in Ramallah than in Hebron and affected more girls than boys. Using the 2000 CDC reference, the prevalence of overweight and obesity in Ramallah among boys was 9.6% and 8.2%, respectively versus 15.6% and 6.0% among girls (P < 0.01). In Hebron, the corresponding figures were 8.5% and 4.9% for boys and 13.5% and 3.4% for girls (P < 0.01). Using the IOTF criteria, the prevalence of overweight and obesity among boys in Ramallah was 13.3% and 5.2%, respectively versus 18.9% and 3.3% for girls. The prevalence of overweight and obesity among boys in Hebron was 10.9% and 2.2%, respectively versus 14.9% and 2.0% for girls. Overweight/obesity was associated with high standard of living (STL) among boys and with the onset of puberty among girls. More boys were underweight than girls, and the prevalence was higher in Hebron (12.9% and 6.0% in boys and girls, respectively (P < 0.01)) than in Ramallah (9.7% and 3.1% in boys and girls, respectively (p < 0.01)). The prevalence of stunting was similar in both governorates, and was higher among boys (9.2% and 9.4% in Ramallah and Hebron, respectively) than among girls (5.9% and 4.2% in Ramallah and Hebron, respectively). Stunting was negatively associated with father's education among boys and with urban residence, medium STL and onset of puberty among girls.</p> <p>Conclusion</p> <p>Under- and overnutrition co-exist among Palestinian adolescents, with differences between sexes. Region, residence, STL, and onset of puberty were associated factors.</p

Fast and accurate mutation detection in whole genome sequences of multiple isogenic samples with IsoMut

Background: Detection of somatic mutations is one of the main goals of next generation DNA sequencing. A wide range of experimental systems are available for the study of spontaneous or environmentally induced mutagenic processes. However, most of the routinely used mutation calling algorithms are not optimised for the simultaneous analysis of multiple samples, or for non-human experimental model systems with no reliable databases of common genetic variations. Most standard tools either require numerous in-house post filtering steps with scarce documentation or take an unpractically long time to run. To overcome these problems, we designed the streamlined IsoMut tool which can be readily adapted to experimental scenarios where the goal is the identification of experimentally induced mutations in multiple isogenic samples. Methods: Using 30 isogenic samples, reliable cohorts of validated mutations were created for testing purposes. Optimal values of the filtering parameters of IsoMut were determined in a thorough and strict optimization procedure based on these test sets. Results: We show that IsoMut, when tuned correctly, decreases the false positive rate compared to conventional tools in a 30 sample experimental setup; and detects not only single nucleotide variations, but short insertions and deletions as well. IsoMut can also be run more than a hundred times faster than the most precise state of art tool, due its straightforward and easily understandable filtering algorithm. Conclusions: IsoMut has already been successfully applied in multiple recent studies to find unique, treatment induced mutations in sets of isogenic samples with very low false positive rates. These types of studies provide an important contribution to determining the mutagenic effect of environmental agents or genetic defects, and IsoMut turned out to be an invaluable tool in the analysis of such data. © 2017 The Author(s)