210— Factors Affecting Teenage Pregnancy in the Philippines

The Philippines has one of the highest adolescent birth rates among the Southeast Asian countries. In 2019, the Philippines National Economic and Development Authority (NEDA) declared the number of teenage pregnancies a national social emergency . Rodrigo Duterte, the President of the Philippines, realized the urgency as the Commission on Population and Development in 2019 recorded that almost seven girls, aged ten to fourteen, gave birth everyday- 2,411 girls that year. Teenage pregnancy prevents the opportunity for women to escape from poverty and improve their human development levels. Increased risk of these outcomes are predominantly caused by inadequate sex education, lack of access to birth control, increasing cohabitation, and misconceptions led by religion or stereotypes. Trade is crucial to increase women\u27s employment and wages. Leveraging trade to increase women\u27s education and empowerment is essential for a sustainable path to significant development. The research examines the policies implemented to tackle important determinants of teen pregnancy and connects trade policies within the Philippines to measure the profound impact of trade on girls\u27 education and empowerment

Sustainability and Replicability of Multiple-Use Water Systems (MUS)

The concept of multiple-use water services and systems (MUS) has received increasingattention in international water and development fora and has emerged as a promising wayto enhance the social and gender equity and productivity of water systems designed forsingle use, e.g. for irrigation or water supply. In Nepal, several MUS models have beenpiloted and implemented for more than a decade by the International DevelopmentEnterprises (iDE) and a few other development organizations. Whereas the short-termbenefits of these systems on gender relationships, women's empowerment, nutrition andhealth have been documented, the sustainability and resilience of these systems has not yetbeen analyzed. The latter is the focus of the research study presented in this report, whichwas conducted by the International Water Management Institute (IWMI) in Western Nepalas part of the USAID-funded Market Access and Water Technology for Women (MAWTW)project

Improved trapping and handling of an arboreal, montane mammal: Red Panda Ailurus fulgens

It is sometimes essential to have an animal in the hand to study some of their ecological and biological characteristics. However, capturing a solitary, cryptic, elusive arboreal species such as the red panda in the wild is challenging. We developed and successfully tested a protocol for tracking, trapping, immobilization, and handling of red pandas in the wild in eastern Nepal. We established a red panda sighting rate of 0.89 panda/day with a capture success rate of 0.6. We trapped and collared one animal in 3.7 days. On average, we took nearly 136 (range 50–317) min to capture an animal after spotting it. Further processing was completed in 38.5 (21–70) min. Before capture, we found it difficult to recognize the sex of the red panda and to differentiate sub-adults above six months from adults. However, body weight, body length, tail length, shoulder height, and chest girth can be used for diagnosis, as these attributes are smaller in sub-adults. Our method is a welfare-friendly way of trapping and handling wild red pandas. We report new morphometric data that could serve as a guide for field identification

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

TDMA scheduling in wireless sensor networks

In this thesis, we address the time slot scheduling problem that arises while utilizing time division multiple access (TDMA) as the medium access control (MAC) protocol for wireless sensor networks (WSN). We first propose two algorithms: Centralized link scheduling and channel assignment algorithm, and distributed broadcast TDMA scheduling algorithm (DB-TDMA), to solve the scheduling problem. The centralized link scheduling and channel assignment algorithm allocates receiving channels to each node and allocates time slot to each link between two nodes. Prior to link scheduling algorithm, a balanced tree formation algorithm is introduced to generate a balanced tree structured network topology. Another proposed scheduling algorithm is the distributed broadcast TDMA scheduling algorithm (DB-TDMA), that allows each node to select its own time slot based on the local two-hop neighbourhood information. Here, an option to obtain either global time framing or local time framing after .We focus on reducing the message transaction between the nodes without compromising the convergence time of the algorithm. We also present an extension to the distributed broadcasts scheduling algorithm to provide multiple time slots to some nodes. Finally, we present the performance analysis of the algorithms presented in this thesis. Our experimental results show that: 1) In centralized link scheduling and channel assignment algorithm, the schedule length decreases with the increase in number of available channels. The decrease is maximum when channel availability increases from one to two. However, the decrease in schedule length becomes -less significant when channel availability is more than two; 2) The DB-TDMA and its extension provides optimal time slot schedule with low message transactions within reasonable run time; 3) The performance of DB-TDMA is observed to better than previously proposed distributed algorithms; distributed randomized TDMA scheduling (DRAND) and deterministic distributed TDMA scheduling (DDTDMA) algorithms in terms of message actions required for scheduling

Characterization of CAP5.5 and CAP5.5V, atypical calpains in Trypanosoma brucei

Calpains are a group of calcium-dependent cysteine proteases with roles ranging from cytoskeletal remodelling to signal transduction. In Trypanosoma brucei, the causal agent of African sleeping sickness, an unusually large number of calpain- like proteins exist, whose functions remain unknown. Recently, the procyclic form- specific cytoskeleton associated protein 5.5 (CAP5.5) and its bloodstream-specific paralogous variant, CAP5.5V were discovered to be essential for the proper morphogenesis of the parasite. However, precise functional roles of these proteins remain unknown. In this MSc thesis, I employed a two-pronged approach combining cell biology studies of CAP5.5 and CAP5.5V in T. brucei with in vitro assays of recombinant calpains expressed in Escherichia coli to further characterize CAP5.5 and CAP5.5V. To resolve whether the function of CAP5.5 and CAP5.5V is dependent upon proteolytic activity, I expressed and purified recombinant CAP5.5V’s catalytic domain. I demonstrated that this domain did not have any detectable autolytic activity or activity against universal protease substrates such as casein. Ectopic expression of CAP5.5::YFP::Ty in procyclic trypanosomes led to nuclear mis-positioning among other morphological defects. Additionally, I demonstrated a cell cycle dependency on incorporation of CAP5.5::YFP::Ty into the cytoskeleton and corroborate previous data that suggest that CAP5.5 is built in from the dynamic, posterior end of the cell. Investigation of the molecular determinants in CAP5.5’s sequence such as motifs or domains suggested that CAP5.5’s domain IV may be the domain mediating association with the sub-pellicular cytoskeleton.This thesis is not currently available in ORA

Climate change, out-migration and agrarian stress: the potential for upscaling small-scale water storage in Nepal.

Climate change could have a critical impact on agriculture in Nepal due to dry-season water shortages, and changes in the variability of water availability and associated uncertainty. This makes water storage systems (most notably ponds and tanks) increasingly important. This report explores the potential role of small-scale water storage infrastructure in two subbasins within the larger Koshi River Basin in central and eastern Nepal, yet shows that upscaling such infrastructure requires an appreciation of the other drivers of change in agriculture aside from climate (e.g., rising cost of living and poor terms of trade for agriculture). It also identifies the social relations and dynamics (distribution of land, water and labor) which could mediate the success of future interventions. It is clear from the research that, while small-scale water storage has the potential to significantly strengthen livelihoods in the Nepali hills, it is necessary to tailor projects to the existing political-economic context

Distribution and habitat use of red panda in the Chitwan-Annapurna Landscape of Nepal

In Nepal, the red panda (Ailurus fulgens) has been sparsely studied, although its range covers a wide area. The present study was carried out in the previously untapped Chitwan-Annapurna Landscape (CHAL) situated in central Nepal with an aim to explore current distributional status and identify key habitat use. Extensive field surveys conducted in 10 red panda range districts were used to estimate species distribution by presence-absence occupancy modeling and to predict distribution by presence-only modeling. The presence of red pandas was recorded in five districts: Rasuwa, Nuwakot, Myagdi, Baglung and Dhading. The predictive distribution model indicated that 1,904.44 km of potential red panda habitat is available in CHAL with the protected area covering nearly 41% of the total habitat. The habitat suitability analysis based on the probability of occurrence showed only 16.58% (A = 315.81 km ) of the total potential habitat is highly suitable. Red Panda occupancy was estimated to be around 0.0667, indicating nearly 7% (218 km ) of the total habitat is occupied with an average detection probability of 0.4482±0.377. Based on the habitat use analysis, altogether eight variables including elevation, slope, aspect, proximity to water sources, bamboo abundance, height, cover, and seasonal precipitation were observed to have significant roles in the distribution of red pandas. In addition, 25 tree species were documented from red panda sign plots out of 165 species recorded in the survey area. Most common was Betula utilis followed by Rhododendron spp. and Abies spectabilis. The extirpation of red pandas in previously reported areas indicates a need for immediate action for the long-term conservation of this species in CHAL