Project risk screening matrix for stream management and restoration

The ‘Project Risk Screening Matrix’ derives from a broader effort to assist US government agency staff in reviewing proposed stream management and restoration projects more efficiently and effectively. The River Restoration Analysis Tool (RiverRAT) developed through this effort provides a thorough, comprehensive and auditable approach to review and evaluation of proposed stream actions and projects (www.restorationreview.com). The matrix was initially developed as the first step in applying the RiverRAT, its purpose being to assist reviewers in assessing the risk to natural resources associated with a particular proposal and matching the intensity of their review to the severity of that risk. Hence, the primary application of the matrix to date has been to identify and screen out low risk projects that may be dealt with expeditiously, and so freeing the time and technical resources needed to allow deep reviews of higher risk projects. A second form of screening emerged from this primary function because the matrix proved adept at identifying the minimum level of site and project characterization required to support initial risk assessment. On this basis, proposals lacking adequate information can also be screened out, being referred back to the proponent with a request for additional information. More recently, new and novel versions of the matrix, featuring modification and refinement of one or both of the original axes, have emerged to widen and refine its application to linear infrastructure (e.g. pipelines, roads, and electrical transmission lines), instream structures (e.g. large wood placement and culvert removal), and pre-application, regulatory, decision-support tools

Project risk screening matrix for stream management and restoration

The ‘Project Risk Screening Matrix’ derives from a broader effort to assist US government agency staff in reviewing proposed stream management and restoration projects more efficiently and effectively. The River Restoration Analysis Tool (RiverRAT) developed through this effort provides a thorough, comprehensive and auditable approach to review and evaluation of proposed stream actions and projects (www.restorationreview.com). The matrix was initially developed as the first step in applying the RiverRAT, its purpose being to assist reviewers in assessing the risk to natural resources associated with a particular proposal and matching the intensity of their review to the severity of that risk. Hence, the primary application of the matrix to date has been to identify and screen out low risk projects that may be dealt with expeditiously, and so freeing the time and technical resources needed to allow deep reviews of higher risk projects. A second form of screening emerged from this primary function because the matrix proved adept at identifying the minimum level of site and project characterization required to support initial risk assessment. On this basis, proposals lacking adequate information can also be screened out, being referred back to the proponent with a request for additional information. More recently, new and novel versions of the matrix, featuring modification and refinement of one or both of the original axes, have emerged to widen and refine its application to linear infrastructure (e.g. pipelines, roads, and electrical transmission lines), instream structures (e.g. large wood placement and culvert removal), and pre-application, regulatory, decision-support tools

Under Pressure: Quenching Star Formation in Low-Mass Satellite Galaxies via Stripping

Recent studies of galaxies in the local Universe, including those in the Local Group, find that the efficiency of environmental (or satellite) quenching increases dramatically at satellite stellar masses below ~ $10^8\ {\rm M}_{\odot}$. This suggests a physical scale where quenching transitions from a slow "starvation" mode to a rapid "stripping" mode at low masses. We investigate the plausibility of this scenario using observed HI surface density profiles for a sample of 66 nearby galaxies as inputs to analytic calculations of ram-pressure and viscous stripping. Across a broad range of host properties, we find that stripping becomes increasingly effective at $M_{*} < 10^{8-9}\ {\rm M}_{\odot}$, reproducing the critical mass scale observed. However, for canonical values of the circumgalactic medium density ($n_{\rm halo} < 10^{-3.5}$${\rm cm}^{-3}$), we find that stripping is not fully effective; infalling satellites are, on average, stripped of < 40 - 70% of their cold gas reservoir, which is insufficient to match observations. By including a host halo gas distribution that is clumpy and therefore contains regions of higher density, we are able to reproduce the observed HI gas fractions (and thus the high quenched fraction and short quenching timescale) of Local Group satellites, suggesting that a host halo with clumpy gas may be crucial for quenching low-mass systems in Local Group-like (and more massive) host halos.Comment: updated version after review, now accepted to MNRAS; Accepted 2016 August 22. Received 2016 August 18; in original form 2016 June 2

Fractal-like Distributions over the Rational Numbers in High-throughput Biological and Clinical Data

Recent developments in extracting and processing biological and clinical data are allowing quantitative approaches to studying living systems. High-throughput sequencing, expression profiles, proteomics, and electronic health records are some examples of such technologies. Extracting meaningful information from those technologies requires careful analysis of the large volumes of data they produce. In this note, we present a set of distributions that commonly appear in the analysis of such data. These distributions present some interesting features: they are discontinuous in the rational numbers, but continuous in the irrational numbers, and possess a certain self-similar (fractal-like) structure. The first set of examples which we present here are drawn from a high-throughput sequencing experiment. Here, the self-similar distributions appear as part of the evaluation of the error rate of the sequencing technology and the identification of tumorogenic genomic alterations. The other examples are obtained from risk factor evaluation and analysis of relative disease prevalence and co-mordbidity as these appear in electronic clinical data. The distributions are also relevant to identification of subclonal populations in tumors and the study of the evolution of infectious diseases, and more precisely the study of quasi-species and intrahost diversity of viral populations

Re-evaluation of cosmic ray cutoff terminology

The study of cosmic ray access to locations inside the geomagnetic field has evolved in a manner that has led to some misunderstanding and misapplication of the terminology originally developed to describe particle access. This paper presents what is believed to be a useful set of definitions for cosmic ray cutoff terminology for use in theoretical and experimental cosmic ray studies

Enumeration of States in a Periodic Glass

We present an analytic enumeration of the metastable states, $N_s$, in a periodic long-range Josephson array frustrated by a transverse field. We find that the configurational entropy, $S_{conf} \equiv \ln N_s$, is extensive and scales with frustration, confirming that the non-random system is glassy. We also find that $S_{conf}$ is different from that of its disordered analogue, despite that fact that the two models share the same dynamical equations

Hydrogen atom in a spherical well: linear approximation

We discuss the boundary effects on a quantum system by examining the problem of a hydrogen atom in a spherical well. By using an approximation method which is linear in energy we calculate the boundary corrections to the ground-state energy and wave function. We obtain the asymptotic dependence of the ground-state energy on the radius of the well.Comment: Revised version to appear in European Journal of Physic

Dopamine D_2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive 4 nicotinic receptors via a cholinergic-dependent mechanism

Recent studies suggest that high-affinity neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits (α4β2*) functionally interact with G-protein-coupled dopamine (DA) D_2 receptors in basal ganglia. We hypothesized that if a functional interaction between these receptors exists, then mice expressing an M2 point mutation (Leu9'Ala) rendering 4 nAChRs hypersensitive to ACh may exhibit altered sensitivity to a D_2-receptor agonist. When challenged with the D_(2)R agonist, quinpirole (0.5–10 mg/kg), Leu9'Ala mice, but not wild-type (WT) littermates, developed severe, reversible motor impairment characterized by rigidity, catalepsy, akinesia, and tremor. While striatal DA tissue content, baseline release, and quinpirole-induced DA depletion did not differ between Leu9'Ala and WT mice, quinpirole dramatically increased activity of cholinergic striatal interneurons only in mutant animals, as measured by increased c-Fos expression in choline acetyltransferase (ChAT)-positive interneurons. Highlighting the importance of the cholinergic system in this mouse model, inhibiting the effects of ACh by blocking muscarinic receptors, or by selectively activating hypersensitive nAChRs with nicotine, rescued motor symptoms. This novel mouse model mimics the imbalance between striatal DA/ACh function associated with severe motor impairment in disorders such as Parkinson’s disease, and the data suggest that a D_(2)R–α4*-nAChR functional interaction regulates cholinergic interneuron activity.—Zhao-Shea, R., Cohen, B. N., Just, H., McClure-Begley, T., Whiteaker, P., Grady, S. R., Salminen, O., Gardner, P. D., Lester, H. A., Tapper, A. R. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive α4 nicotinic receptors via a cholinergic-dependent mechanism

Social presence in the 21st Century: an adjustment to the Community of Inquiry framework

The Community of Inquiry framework, originally proposed by Garrison, Anderson and Archer (2000) identifies teaching, social and cognitive presences as central to a successful online educational experience. This article presents the findings of a study conducted in Uruguay between 2007 and 2010. The research aimed to establish the role of cognitive, social and teaching presences in the professional development of 40 English language teachers on Continuous Professional Development (CPD) programmes delivered in blended learning settings. The findings suggest that teaching presence and cognitive presence have themselves 'become social'. The research points to social presence as a major lever for engagement, sense-making and peer support. Based on the patterns identified in the study, this article puts forward an adjustment to the Community of Inquiry framework, which shows social presence as more prominent within the teaching and cognitive constructs than the original version of the framework suggests