The using of the technology of forming design competence in the educational process of secondary professional education

Specific character of organizing of project competence of future clothes design specialists in institutions of secondary professional training is considered in the article. Content of profes-sional training is opened on the base of using in educational process technologies of forming project competenceВ статье рассматривается специфика формирования проектной компетентности у будущих специалистов дизайна одежды в образовательных организациях среднего профессионального образования. Содержание профессиональной подготовки обучающихся раскрывается на основе использования в учебном процессе технологий формирования проектной компетентност

Covalent Binding Antibodies Suppress Advanced Glycation: On the Innate Tier of Adaptive Immunity

Non-enzymatic protein glycation is a source of metabolic stress that contributes to cytotoxicity and tissue damage. Hyperglycemia has been linked to elevation of advanced glycation endproducts, which mediate much of the vascular pathology leading to diabetic complications. Enhanced glycation of immunoglobulins and their accelerated vascular clearance is proposed as a natural mechanism to intercept alternative advanced glycation endproducts, thereby mitigating microvascular disease. We reported that antibodies against the glycoprotein KLH have elevated reactivity for glycopeptides from diabetic serum. These reactions are mediated by covalent binding between antibody light chains and carbonyl groups of glycated peptides. Diabetic animals that were immunized to induce reactive antibodies had attenuated diabetic nephropathy, which correlated with reduced levels of circulating and kidney-bound glycation products. Molecular analysis of antibody glycation revealed the preferential modification of light chains bearing germline-encoded lambda V regions. We previously noted that antibody fragments carrying V regions in the germline configuration are selected from a human Fv library by covalent binding to a reactive organophosphorus ester. These Fv fragments were specifically modified at light chain V region residues, which map to the combining site at the interface between light and heavy chains. These findings suggest that covalent binding is an innate property of antibodies, which may be encoded in the genome for specific physiological purposes. This hypothesis is discussed in context with current knowledge of the natural antibodies that recognize altered self molecules and the catalytic autoantibodies found in autoimmune disease

Features of forming of project competence are in the system of secondary professional education

In the article the theoretical and practical aspects of forming of project competence are examined for future specialists in the system of secondary professional educationРассматриваются теоретические и практические аспекты формирования проектной компетентности у будущих специалистов в системе среднего профессионального образовани

FOLK ART AS A MEANS OF CREATIVE SELF-DEVELOPMENT OF STUDENTS

В статье рассматриваются возможности использования технологий народного искусства как средства творческого саморазвития студентов. Прослежена зависимость между творческим наследием народа и творческим саморазвитием в условиях среднего профессионального образованияThe article considers the possibilities of using folk art technologies as a means of creative self-development of students. The author traces the relationship between the creative heritage of the people and creative self-development in the conditions of secondary vocational educatio

Modern Educational Technologies in the Training of Middle-Level Specialists

В статье рассматриваются современные технологии обучения в условиях среднего профессионального образования. Проведенный анализ результатов исследования позволяет сделать вывод, что использование современных образовательных технологий в профессиональном образовании является важным условием развития индивидуальных психологических и личностных характеристик обучающихся.The article deals with modern technologies of teaching in the conditions of secondary vocational education. The analysis of the results of the use allows us to conclude that the use of modern educational technologies in vocational education is an important condition for the development of individual psychological and personal characteristics of students

Assessment of the student’s educational experience as a tool for making management decisions in the university

This article draws attention to students’ educational experience at a Russian regional university. Such experience is based on two aspects: on the one hand, it is a result of abilities integration, and on the other, it is an ability to act in a context of uncertainty. The latter aspect in understanding students’ experience is the most important for the personality formation in today’s complex world. Within the context of the higher education transformation, experience as an ability to act plays a significant role in individual development. That is why this study is aimed at analyzing the educational experience of first-year students and university graduates. Their educational experience is assessed based on their involvement in educational practices in class, in research activities at the university, and in self-educational activities. The results show that the first-year students’ experience and the graduates’ one at the university have functional differences. The first-year students’ academic engagement is higher as compared to the graduate students’. The research experience of both is expressed in a low degree. The self-educational experience at the university is not strategically formed. Comparing the first-year students’ and the graduates’ educational experiences, one can conclude that the structure of the latter is more functional due to the graduates’ limited involvement in educational activities. This means that the educational experience varies during the period of studies mainly in individual competencies, which are not connected with each other. The low level of the students’ involvement in educational practice reflects the weak development of their experience as an ability to act. It is the structure of a student’s motives that can be one of the main factors of his/her involvement in the learning process. Our findings contribute to the design of educational practices at the university and suggest the strong demand for a more responsible approach to designing the educational environment and educational practices at all university levels.В данной исследовательской статье предлагается обратить внимание на образовательный опыт студентов в региональном университете. Образовательный опыт можно понимать в двух аспектах: и как результат интеграции способностей, и как способность к действию в условиях неопределенности. Последний аспект в понимании опыта является наиболее важным для формирования личности в условиях сложного мира. В ситуации трансформации высшего образования опыт как способность к действию играет значимую роль в развитии личности, поэтому цель проведенного исследования состояла в анализе образовательного опыта студентов первого и выпускного курсов. Образовательный опыт студентов оценивался по их вовлеченности в образовательные практики непосредственно в аудитории, а также в научную деятельность в университете и самообразовательную деятельность. Результаты показали, что опыт студентов первого курса и выпускников в данном региональном университете имеет функциональные различия. Студенты первого курса проявляют более высокую образовательную активность по сравнению со студентами, обучающимися на выпускном курсе. Научно-исследовательский опыт обеих когорт студентов выражен в низкой степени. Опыт самостоятельных активностей в вузе или опыт самообразования целенаправленно не формируется. Сравнивая образовательный опыт студентов первого и выпускного курсов, можно заключить, что для выпускников структура опыта выглядит более функционально, такой вывод следует из их невысокой вовлеченности в образовательные практики по сравнению с первокурсниками. Это означает, что образовательный опыт от курса к курсу меняется преимущественно в отдельных компетенциях, не связанных друг с другом. Низкая вовлеченность студентов в образовательные практики говорит о слабом развитии у них опыта как способности к действию. Установлено, что одним из важных факторов вовлеченности в образовательный процесс, а значит, и формирования образовательного опыта студента выступает структура его мотивов. Полученные результаты вносят определенный вклад в проектирование образовательных практик в университете и говорят о необходимости более ответственного подхода к проектированию образовательной среды и образовательных практик на всех уровнях университета

МНОГООБРАЗИЯ КОМПЛЕКСНОГО И ВЕЩЕСТВЕННОГО ЦЕНТРА ДВУМЕРНЫХ АВТОНОМНЫХ ПОЛИНОМИАЛЬНЫХ ДИФФЕРЕНЦИАЛЬНЫХ СИСТЕМ

In the present article we consider the interaction between the solution of the problem of obtaining necessary and sufficient conditions of existence of a time-independent first integral analytical in the neighborhood of the origin for the complex system of the form x = y + P(x, y), y = −x + Q(x, y), where P(x, y), Q(x, y) are polynomials without constant and linear terms, and the solution of the center-focus problem for the real system of the same form.В работе показана связь между решением задачи получения необходимых и достаточных условий существования аналитического в окрестности начала координат первого интеграла, не зависящего от времени, для комплексной системы вида x = y + P(x, y), y = −x + Q(x, y), где P(x, y), Q(x, y) – полиномы без свободных и линейных членов, и решением проблемы различения центра и фокуса для вещественного аналога этой системы

Combined QCD and electroweak analysis of HERA data

A simultaneous fit of parton distribution functions (PDFs) and electroweak parameters to HERA data on deep inelastic scattering is presented. The input data are the neutral current and charged current inclusive cross sections which were previously used in the QCD analysis leading to the HERAPDF2.0 PDFs. In addition, the polarisation of the electron beam was taken into account for the ZEUS data recorded between 2004 and 2007. Results on the vector and axial-vector couplings of the Z boson to u- and d-type quarks, on the value of the electroweak mixing angle and the mass of the W boson are presented. The values obtained for the electroweak parameters are in agreement with Standard Model predictions.Comment: 32 pages, 10 figures, accepted by Phys. Rev. D. Small corrections from proofing process and small change to Fig. 12 and Table

Limits on the effective quark radius from inclusive epep scattering at HERA

The high-precision HERA data allows searches up to TeV scales for Beyond the Standard Model contributions to electron-quark scattering. Combined measurements of the inclusive deep inelastic cross sections in neutral and charged current $ep$ scattering corresponding to a luminosity of around 1 fb$^{-1}$ have been used in this analysis. A new approach to the beyond the Standard Model analysis of the inclusive $ep$ data is presented; simultaneous fits of parton distribution functions together with contributions of "new physics" processes were performed. Results are presented considering a finite radius of quarks within the quark form-factor model. The resulting 95% C.L. upper limit on the effective quark radius is $0.43\cdot 10^{-16}$ cm.Comment: 10 pages, 4 figures, accepted by Phys. Lett.

Search for a narrow baryonic state decaying to pKS0{pK^0_S} and pˉKS0{\bar{p}K^0_S} in deep inelastic scattering at HERA

A search for a narrow baryonic state in the $pK^0_S$ and $\bar{p}K^0_S$ system has been performed in $ep$ collisions at HERA with the ZEUS detector using an integrated luminosity of 358 pb$^{-1}$ taken in 2003-2007. The search was performed with deep inelastic scattering events at an $ep$ centre-of-mass energy of 318 GeV for exchanged photon virtuality, $Q^2$, between 20 and 100 $\rm{} GeV^{2}$. Contrary to evidence presented for such a state around 1.52 GeV in a previous ZEUS analysis using a sample of 121 pb$^{-1}$ taken in 1996-2000, no resonance peak was found in the $p(\bar{p})K^0_S$ invariant-mass distribution in the range 1.45-1.7 GeV. Upper limits on the production cross section are set.Comment: 16 pages, 4 figures, accepted by Phys. Lett. B. Minor changes from journal reviewing process, including a small correction to figure