Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: A gene required for repair of double strand break and recombination

A new Schizosaccharomyces pombe mutant (rad32) which is sensitive to gamma and UV irradiation is described. Pulsed field gel electrophoresis of DNA from irradiated cells indicates that the rad32 mutant, in comparison to wild type cells, has decreased ability to repair DNA double strand breaks. The mutant also undergoes decreased meiotic recombination and displays reduced stability of minichromosomes. The rad32 gene has been cloned by complementation of the UV sensitive phenotype. The gene, which is not essential for cell viability and is expressed at a moderate level in mitotically dividing cells, has significant homology to the meiotic recombination gene MRE11 of Saccharomyces cerevisiae. Epistasis analysis indicates that rad32 functions in a pathway which includes the rhp51 gene (the S. pombe homologue to S. cerevisiae RAD51) and that cells deleted for the rad32 gene in conjunction with either the rad3 deletion (a G2 checkpoint mutation) or the rad2 deletion (a chromosome stability and potential nucleotide excision repair mutation) are not viable

Considering DG in Expansion Planning of Subtransmission System

Deregulation has been obtained new options in the design and planning of the power system. One of these options is the integration of Distributed Generation (DG) into the power system. In this paper, the presence of distributed generation is regarded as another alternative for supplying the load of subtransmission system. The effects of DG on expansion planning of subtransmission system have been modeled as an  optimization problem where the Genetic Algorithm (GA) and Linear Programming (LP) are employed to solve it. The proposed approach is applied to a realistic subtransmission system and the results are evaluated

Removal of malathion insecticide from water by employing acoustical wave technology

Background: Organophosphorus pesticides are one of the most prevalent usages for pest control in the country. Such pesticides enter into water sources by different routes. Since drinking of contaminated water at the higher doses than the standard level, may causes undesirable effects to human health and ecosystem. The object of this research was to investigate the effect of various parameters including time, power and concentration on sonodecomposition of malathion insecticide in the water. Methods: The sonochemical degradation of malathion was investigated using acoustic wave technology (AWT). AWT with 130 kHz was used to study the decomposition of insecticide solution. Samples were analyzed using HPLC at different intervals times. Effectiveness of AWT at different times (20, 40, 60, 80, 100, and 120 minutes), concentrations of malathion at 2, 4 and 8 mg/L as well as powers of device (300W, 400W, 500W) are compared. Results: These findings showed that the degradation of the malathion insecticide at lower concentrations was greater in comparison to higher concentrations. Also, there was positive correlation between power increasing and the ability to malathion degradation Conclusion: The sonodegradation of malathion at different concentrations and powers was successfully achieved. It has been shown that acoustical wave technology can be used to reduce the concentration of dissolved insecticide using high frequency

Robust state feedback controller design of STATCOM using chaotic optimization algorithm

In this paper, a new design technique for the design of robust state feedback controller for static synchronous compensator (STATCOM) using Chaotic Optimization Algorithm (COA) is presented. The design is formulated as an optimization problem which is solved by the COA. Since chaotic planning enjoys reliability, ergodicity and stochastic feature, the proposed technique presents chaos mapping using Lozi map chaotic sequences which increases its convergence rate. To ensure the robustness of the proposed damping controller, the design process takes into account a wide range of operating conditions and system configurations. The simulation results reveal that the proposed controller has an excellent capability in damping power system low frequency oscillations and enhances greatly the dynamic stability of the power systems. Moreover, the system performance analysis under different operating conditions shows that the phase based controller is superior compare to the magnitude based controller

Quantum Rejection Sampling

Let H be a finite dimensional Hilbert space and ρ, σ ∈ D(H) be quantum states in H such that S(ρ||σ) is finite. In this thesis, we consider the following communication task involving two parties Alice and Bob. Suppose that Alice is given a classical description of the states ρ and σ. Given an unlimited number of copies of an entangled state whose marginal on Bob’s side is σ, Alice’s goal is to help Bob output a single copy of the state ρ by sending a single message to Bob in a one-way LOCC (short for local operation and classical communication) protocol. We propose a class of one-way LOCC protocols for this task which we refer to as quantum rejection sampling protocols. Inspired by the classical rejection sampling protocol of Harsha, Jain, McAllester, and Radhakrishnan [25] for a similar classical communication task, we introduce the Greedy Quantum Rejection Sampler. We characterize the expected communication cost of the protocol in terms of max-relative entropy of ρ with respect to σ, in the case where the state ρ is a pure state and prove that the Greedy Quantum Rejection Sampler is an optimal quantum rejection sampling protocol in this case. We describe an optimal quantum rejection sampling protocol in terms of a semidefinite program and we find general lower bounds and upper bounds on the expected communication cost of the optimal protocol. We propose an LOCC compression protocol based on the Greedy Quantum Rejection Sampler protocol, for lossless compression of an arbitrary pure state quantum source in the visible compression model and we show an upper bound on the average length of this encoding. The upper bound is always less than or equal to the Shannon entropy of the quantum source and the gap between the two quantities can be arbitrary large. Finally, we introduce a high-entanglement deterministic exact protocol for remote preparation of an arbitrary ensemble of quantum states. Our protocol is based on a quantum rejection sampling protocol which uses a prefix-free encoding for communication of the messages. We establish an upper bound on the expected communication cost of this protocol for the worst case choice of the target state in terms of the max-information in Bob’s output register at the end of the protocol about Alice’s classical input register. Furthermore, this protocol can be used as a non-oblivious universal protocol for exact remote preparation of an arbitrary d-dimensional state at an expected communication cost of at most lg(d) +O (lg(lg(d))).4 month

Noisy Interactive Quantum Communication

We consider the problem of implementing two-party interactive quantum communication over noisy channels, a necessary endeavor if we wish to fully reap quantum advantages for communication. For an arbitrary protocol with n messages, designed for noiseless qudit channels (where d is arbitrary), our main result is a simulation method that fails with probability less than 2⁻ᶿ⁽ⁿᵋ⁾ and uses a qudit channel n(1 + Θ(√ε)) times, of which ε fraction can be corrupted adversarially. The simulation is thus capacity achieving to leading order, and we conjecture that it is optimal up to a constant factor in the √ε term. Furthermore, the simulation is in a model that does not require pre-shared resources such as randomness or entanglement between the communicating parties. Surprisingly, this outperforms the best known overhead of 1 + O(√(ε log log 1/ε)) in the corresponding classical model, which is also conjectured to be optimal [Haeupler, FOCS’14]. Our work also improves over the best previously known quantum result where the overhead is a non-explicit large constant [Brassard et al., FOCS’14] for small ε

Oral Midazolam Vs Promethazine as Pre Sedation Medication in Pediatric Dentistry

Objectives Pre- and post-sedation effect of oral Midazolam to promethazine in2-6 yrs old fearful children for dental treatmentMethods This randomized clinical trial was carried out on a group of 26 children aged 2-6 years referred to the dental school due to their fear and multiple dental needs. Patients were selected from ASA I or II classification and scored 1 in Frankl Behavior scale. Each patient was scheduled for two subsequent visits to receive one of the two pre medications before IV sedation. Each patient served as self-control and randomly assigned to either group A: receiving Midazolam oral as premed in 1st visit or group B: receiving Promethazine oral as the premed in 1st visit. Six hour NPO was instructed prior to sedation visit. Monitoring vital signs were conducted at every 15 minutes starting with base line before any drug administration. Sedation score was recorded using Houpt Sedation scale. Post sedation problems were recorded by operator. Data were analyzed using Student t test and Kruskal Wallis.Results No significant difference was noted between the patient perceptions at the two different visits. Children did not show a significant difference on symptoms such as Crying, Movement, Sleep and overall behavior in two visits at the first 15 minutes of sedative injection. Post-operative complications were having no significant difference. Lower sickness and vomiting were reported following promethazine intake.Conclusion Promethazine seems to be as effective and as acceptable premedication as Midazolam in pediatric dentistry