The successfulness of photoastigmatic refractive keratectomy

We evaluated 44 patients totaling 64 eyes that had undergone photoastigmatic refractive keratectomy at Casey Eye Institute, Portland, Oregon for the correction of myopia and astigmatism. The mean entering manifest sphere was -4.11D, the mean cylinder was -1.54D. Forty-five eyes had with-the-rule astigmatism, fifteen had against-the- rule astigmatism, and four eyes had oblique astigmatism. The mean entering best corrected manifest visual acuity was 20/20+ 1. Patients with 6 months of follow-up care showed a mean sphere correction of +0.15D and a mean cylinder correction of -0.57D. The mean best corrected visual acuity was 20/20+ 1, and the mean uncorrected acuity was 20/20-2. These data show that there is a significant and accurate correction of myopic astigmatism with P.A.R.K., and that P.A.R.K. is an effective treatment for patients wanting to undergo vision correction surgery

Synoptic-Scale Precursors, Characteristics and Typing of Nocturnal Mesoscale Convective Complexes in the Great Plains

Mesoscale convective complexes (MCCs) occur frequently during the warm season in the central U.S. and can produce flooding rains, hail and tornadoes. Previous work has found that the synoptic-scale environment can greatly affect, and be affected by, the development and maintenance of MCCs. Ninetytwo MCC cases from 2006–2011 are manually identified using infrared satellite imagery and partitioned into three types (upstream trough, zonal and ridge) using a unique manual synoptic typing based on 500- hPa height patterns. Upstream trough cases feature an amplified longwave 500-hPa trough upstream of the MCC genesis region (GR), while the 500-hPa flow is relatively flat in zonal cases, and a strong 500-hPa ridge is present over the Rockies in ridge cases. Individual case and storm-relative composite analyses of a subset of 28 cases show that of the three types, upstream trough cases feature both the strongest quasigeostrophic forcing for ascent and lower-tropospheric frontogenesis, the latter of which enhances ascent and is associated with a strong southerly low-level jet (LLJ). Zonal and ridge cases feature smaller magnitudes (in descending order) of all ascent-forcing parameters. Ridge cases, in particular, are characterized by weak Q-vector convergence, but easterly upslope flow likely acts as a compensating ascent mechanism. A thermodynamic analysis shows that high-θe air is advected into the GR in all three MCC types, and serves as fuel for development and maintenance. However, while the southerly LLJ advects high-θe air from the Gulf of Mexico in the upstream trough and zonal cases, such air is already pooled in the High Plains in the ridge cases and advected into the GR by easterly flow. In accordance with the synoptic-dynamic analysis, upstream trough cases have the longest duration and largest impact on the synoptic-scale environment, while ridge cases are the shortest-lived. The various underlying precipitation structures of each group are also explored; zonal cases, for example, appear to preferentially be associated with bow echoes

Principles of entrepreneurship (ENT 530): Business model canvas: The Dee Dee’s Chocolate / Shawn O’Neill Anak Kelly

The Dee Dee’s Chocolate are established in the end of the 2019 year. It is a business that are selling popular foods that are usually in high demand during public holidays which is in Raya and Gawai Festive season. Besides this business is a partnership business as the owner of this company which is Shawn O’niel anak Kellly as an owner and with it’s her partnership with his mother which is Nora anak Nanta. It is established due to his mother want to have a business which is selling food. This is because due to her business experience at her young age, it gets the attention of his son. Therefore, its owner is willingly help his mother to fulfil her ambition due to his son has the same passion as her. Besides that, we start selling our product at the end of 2019 till this day. Even though there are some calamities that makes a difficulty to sell our product, it is not enough to break our determination to do our best to make our business to become successful than before. As we can see from the festive season that will be coming soon on June, it is a perfect opportunity to sell our product due to its high demand from people especially at the Kota Samarahan area. Even though there are some slides up and down within our business, we are able to execute our business task with a little difficulty. This is because we are selling our product at reasonable price but at high quality that can satisfy the needs of our customer. Despite having a competitor that sells similar product as us within the Samarahan area, it gives us a healthy competition between each other as it has its own pro and cons while executing the business. In order to keep up with other competitor advantages, we offer a delivery service of our product towards our customer in order to keep our business in good condition. Due to its good feedback from our customer, it shows a positive sign to our business to operate in a long period of time. Without the feedback and critics from our customer, our businesses might not be as successful as it happens on this day. Thus, it gives us a chance to fulfil our goals to be a successful company that are selling the Kuih Chocolate Almond London and Chocolate Cookies without having a problem

Inline voice commands in word processor

Invoking a command in a word processor typically involves a break in the flow of writing. For example, if a user wants to insert a table into a document that she is editing, she has to execute an operation such as pressing a key combination, performing a mouse movement, or a gesture to invoke a command. Such breaks in flow causes a loss of productivity. Further, performing such movements may be difficult for users with motor disabilities. This disclosure describes techniques that enable a user to issue voice commands without a break in the flow of writing

A system for efficient neural stimulation with energy recovery

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2004.Includes bibliographical references (p. 191-195).An analog VLSI-based low-power neural tissue stimulator is presented as a part of the MIT and Massachusetts Eye and Ear Infirmary Retinal Implant Project to develop a prosthesis for restoring some useful vision to patients blinded by retinal degeneration. Such a prosthesis would receive image data from an external camera and electrically stimulate surviving ganglion nerve cells. However, power consumption for this type of implant is dominated by the tissue and electrode-tissue interface, and the current source stimulators generally used are inefficient, limiting battery life and generating potentially damaging temperature increases at the retinal surface. A stimulation system has been developed which delivers the required stimulus charge to the electrodes, but uses far less power than typical stimulators. A traditional current source uses output transistors to limit current, but those transistors can drop substantial voltage, and therefore cost power. The aim of this system is to generate a step-ramp voltage waveform which mimics the electrode voltage (modeled as a series resistance and capacitance) during constant current stimulation. This is implemented with a series of voltage steps, each step a separate power supply.(cont.) Electrodes are switched through a series of steps, and each step is maintained at its prescribed voltage by a controlled synchronous rectifier, which charges the supply capacitor from a single AC secondary power coil. This novel architecture uses less than half of the power used by an aggressively designed current source stimulator with the same voltage rails, and about one-third of the power consumed by typical stimulators used for this function.by Shawn Kevin Kelly.Ph.D

On the Dynamics, Thermodynamics, and Forecast Model Evaluation of Two Snow-Burst Events in Southern Alberta

Two high-impact convective snowband events (‘‘snow bursts’’) that affected Calgary, Alberta, Canada, are examined to better understand the dynamics and thermodynamics of heavy snowbands not associated with lake effects or the cold conveyor belt of synoptic-scale cyclones. Such events are typically characterized by brief, but heavy, periods of snow; low visibilities; and substantial hazards to automobile and aviation interests. Previous literature on these events has been limited to a few case studies across North America, including near the leeside foothills of the U.S. Rockies. The large-scale dynamics and thermodynamics are investigated using the National Centers for Environmental Prediction (NCEP) North American Regional Reanalysis (NARR). Previously, high-resolution convection-explicit Weather Research and Forecasting Model (WRF) simulations have shown some ability to successfully reproduce the dynamics, thermodynamics, and appearance of convective snowbands, with small errors in location and timing. Therefore, WRF simulations are performed for both events, and are evaluated along with the NCEP North American Mesoscale (NAM) model forecasts. Both the NARR and WRF simulations show that while the two snow bursts are similar in appearance, they form as a result of different dynamic and thermodynamic mechanisms. The first event occurs downstream of an upper-tropospheric jet streak in a region of little synoptic-scale ascent, where ageostrophic frontogenesis helps to release conditional, dry symmetric, and inertial instability in an unsaturated environment. The inertial instability is determined to be related to fast flow over upstream high terrain. The second event occurs in a saturated environment in a region of Q-vector convergence (primarily geostrophic frontogenesis), which acts to release conditional, convective, and conditional symmetric instability (CSI)

Qualification of Additive Manufacturing Flaw Fabrication Process for Verification of X-ray Computed Tomography of Complex Geometry Components

Nondestructive Evaluation (NDE) techniques are needed to validate the additive manufacturing (AM) process performance. The lack of adequate NDE techniques for examination before, during and after AM component fabrication was identified as one of the main current challenges [1]. X-ray computed tomography (CT) was selected as primary technique for post-process inspection of components with complex shapes where the advantages of AM are fully realized [2]. To establish an initial baseline of CT data, Direct Metal Laser Melting (DMLM) and Electron Beam Melting (EBM) were used to fabricate coupons and complex geometry aerospace components with typical flaws and conditions. A flaw matrix was designed and the two processes were optimized to produce the desired flaws necessary for verification of CT performance in Inconel 718 and Ti-6Al-4V. Four coupon batches were fabricated. Surface and subsurface flaws were implanted such as pores, up to 135 AM process induced, and 8 machined artificial flaws. All four batches were CT inspected to measure the flaws and compare with the matrix to qualify the flaw fabrication process and determine the range of flaws that could reliably be produced. Coupons were sectioned to verify the CT measurements. CT data showed residual powder and differences between surface and subsurface flaw morphology. Results will be used in subsequent phases of the project to build and CT inspect components with complex shape and geometry for establishing CT baseline capabilities

RYR1 myopathy complicated by RSV bronchiolitis requiring intubation leading to posthypoxic leukoencephalopathy in a 4 year-old.

Central core disease due to RYR1 mutations is a rare heterogeneous myopathy characterized by skeletal muscle weakness. In light of both the rarity of presentation as well as the relatively broad spectrum of clinical phenotypes, there is a need to report treatment strategies for common complications of this condition. In this case, we outline the ICU management of a 4 year-old girl with central core disease caused by RYR1 mutation who was hospitalized due to respiratory syncytial virus (RSV) bronchiolitis leading to respiratory failure. Her hospital stay was complicated by multiple failed extubations, hospital infections, and post-anoxic leukoencephalopathy.&nbsp

Free Market Ideology and Deregulation in Colorado\u27s Oil Fields: Evidence for Triple Movement Activism?

Unconventional oil and gas extraction(UOGE) has spurred an unprecedented boom in on-shore production in the U.S.Despite a surge in related research, a void exists regarding policy-related inquiries.To address this gap, we examine support of federal regulatory exemptions for UOGE using survey data collected in 2015 from two northern Colorado communities as part of a National Institutes of Health study.We assert that current regulatory exemptions for UOGE can be understood as components of broader societal processes of neoliberalization. We test whether free market ideologies relate to people’s regulatory views and find that free market ideology increases public support for federal regulatory exemptions for UOGE.We find that perceived negative impacts do not necessarily drive people to support increased federal regulation. Utilizing neo-Polanyian theory, we tested for an interaction between free market ideology and perceived negative impacts(Block and Somers 2014; Author 2015).Interestingly, free market ideology appears to moderate people’s views of regulation.Free market ideology seems to increase the effect of perceived negative impacts while simultaneously increasing support for deregulation.We conclude with a nuanced theoretical discussion to analyze how free market ideology might normalize the impacts of UOGE activity