522 research outputs found
Advanced Ceramics for Use as Fuel Element Materials in Nuclear Thermal Propulsion Systems
With the recent start (October 2011) of the joint National Aeronautics and Space Administration (NASA) and Department of Energy (DOE) Advanced Exploration Systems (AES) Nuclear Cryogenic Propulsion Stage (NCPS) Program, there is renewed interest in developing advanced ceramics for use as fuel element materials in nuclear thermal propulsion (NTP) systems. Three classes of fuel element materials are being considered under the NCPS Program: (a) graphite composites - consisting of coated graphite elements containing uranium carbide (or mixed carbide), (b) cermets (ceramic/metallic composites) - consisting of refractory metal elements containing uranium oxide, and (c) advanced carbides consisting of ceramic elements fabricated from uranium carbide and one or more refractory metal carbides [1]. The current development effort aims to advance the technology originally developed and demonstrated under Project Rover (1955-1973) for the NERVA (Nuclear Engine for Rocket Vehicle Application) [2]
Male frequent attenders of general practice and their help seeking preferences
Background: Low rates of health service usage by men are commonly linked to masculine values and traditional male gender roles. However, not all men conform to these stereotypical notions of masculinity, with some men choosing to attend health services on a frequent basis, for a variety of different reasons. This study draws upon the accounts of male frequent attenders of the General Practitioner's (GP) surgery, examining their help-seeking preferences and their reasons for choosing services within general practice over other sources of support. Methods: The study extends thematic analysis of interview data from the Self Care in Primary Care study (SCinPC), a large scale multi-method evaluation study of a self care programme delivered to frequent attenders of general practice. Data were collected from 34 semi-structured interviews conducted with men prior to their exposure to the intervention. Results: The ages of interviewed men ranged from 16 to 72 years, and 91% of the sample (n= 31) stated that they had a current health condition. The thematic analysis exposed diverse perspectives within male help-seeking preferences and the decision-making behind men's choice of services. The study also draws attention to the large variation in men's knowledge of available health services, particularly alternatives to general practice. Furthermore, the data revealed some men's lack of confidence in existing alternatives to general practice. Conclusions: The study highlights the complex nature of male help-seeking preferences, and provides evidence that there should be no 'one size fits all' approach to male service provision. It also provides impetus for conducting further studies into this under researched area of interest. © 2011 WPMH GmbH
Simultaneous Pre-and Post-Turbulence Compensation of Multiple Orbital-Angular-Momentum 100-Gbit/s Data Channels in a Bidirectional Link Using a Single Adaptive-Optics System
The simultaneous pre-and post-turbulence compensation of multiple orbital-angular-momentum (OAM) modes propagating through turbulent channel is experimentally demonstrated in a bidirectional free-space optical (FSO) link by using a single adaptive-optics system.United States. Defense Advanced Research Projects Agency. Information in a Photon (InPho) ProgramIntel Corporatio
Roadmaps to Utopia: Tales of the Smart City
Notions of the Smart City are pervasive in urban development discourses. Various frameworks for the development of smart cities, often conceptualized as roadmaps, make a number of implicit claims about how smart city projects proceed but the legitimacy of those claims is unclear. This paper begins to address this gap in knowledge. We explore the development of a smart transport application, MotionMap, in the context of a £16M smart city programme taking place in Milton Keynes, UK. We examine how the idealized smart city narrative was locally inflected, and discuss the differences between the narrative and the processes and outcomes observed in Milton Keynes. The research shows that the vision of data-driven efficiency outlined in the roadmaps is not universally compelling, and that different approaches to the sensing and optimization of urban flows have potential for empowering or disempowering different actors. Roadmaps tend to emphasize the importance of delivering quick practical results. However, the benefits observed in Milton Keynes did not come from quick technical fixes but from a smart city narrative that reinforced existing city branding, mobilizing a growing network of actors towards the development of a smart region. Further research is needed to investigate this and other smart city developments, the significance of different smart city narratives, and how power relationships are reinforced and constructed through them
Observational evidence for the accretion-disk origin for a radio jet in an active galaxy
Accretion of gas onto black holes is thought to power the relativistic jets of material ejected from active galactic nuclei (AGN) and the 'microquasars' located in our Galaxy(1-3). In microquasars, superluminal radio-emitting features appear and propagate along the jet shortly after sudden decreases in the Xray fluxes(1). This establishes a direct observational link between the black hole and the jet: the X-ray dip is probably caused by the disappearance of a section of the inner accretion disk(4) as it falls past the event horizon, while the remainder of the disk section is ejected into the jet, creating the appearance of a superluminal bright spot(5). No such connection has hitherto been established for AGN, because of insufficient multi-frequency data. Here we report the results of three years of monitoring the X-ray and radio emission of the galaxy 3C120. As has been observed for microquasars, we find that dips in the X-ray emission are followed by ejections of bright superluminal knots in the radio jet. The mean time between X-ray dips appears to scale roughly with the mass of the black hole, although there are at present only a few data points.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62888/1/nature00772.pd
Gravitational Geometric Phase in the Presence of Torsion
We investigate the relativistic and non-relativistic quantum dynamics of a
neutral spin-1/2 particle submitted an external electromagnetic field in the
presence of a cosmic dislocation. We analyze the explicit contribution of the
torsion in the geometric phase acquired in the dynamic of this neutral
spinorial particle. We discuss the influence of the torsion in the relativistic
geometric phase. Using the Foldy-Wouthuysen approximation, the non-relativistic
quantum dynamics are studied and the influence of the torsion in the
Aharonov-Casher and He-McKellar-Wilkens effects are discussed.Comment: 14 pages, no figur
Radio Astronomy
Contains reports on seven research projects.M. I. T. Sloan Fund for Basic ResearchNational Science Foundation (Grant GP-8415)Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E)National Aeronautics and Space Administration (Grant NGL 22-009-016
Phylogeography of Japanese encephalitis virus:genotype is associated with climate
The circulation of vector-borne zoonotic viruses is largely determined by the overlap in the geographical distributions of virus-competent vectors and reservoir hosts. What is less clear are the factors influencing the distribution of virus-specific lineages. Japanese encephalitis virus (JEV) is the most important etiologic agent of epidemic encephalitis worldwide, and is primarily maintained between vertebrate reservoir hosts (avian and swine) and culicine mosquitoes. There are five genotypes of JEV: GI-V. In recent years, GI has displaced GIII as the dominant JEV genotype and GV has re-emerged after almost 60 years of undetected virus circulation. JEV is found throughout most of Asia, extending from maritime Siberia in the north to Australia in the south, and as far as Pakistan to the west and Saipan to the east. Transmission of JEV in temperate zones is epidemic with the majority of cases occurring in summer months, while transmission in tropical zones is endemic and occurs year-round at lower rates. To test the hypothesis that viruses circulating in these two geographical zones are genetically distinct, we applied Bayesian phylogeographic, categorical data analysis and phylogeny-trait association test techniques to the largest JEV dataset compiled to date, representing the envelope (E) gene of 487 isolates collected from 12 countries over 75 years. We demonstrated that GIII and the recently emerged GI-b are temperate genotypes likely maintained year-round in northern latitudes, while GI-a and GII are tropical genotypes likely maintained primarily through mosquito-avian and mosquito-swine transmission cycles. This study represents a new paradigm directly linking viral molecular evolution and climate
Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity
Engineered metalloproteins constitute a flexible new class of analyte-sensitive molecular imaging agents detectable by magnetic resonance imaging (MRI), but their contrast effects are generally weaker than synthetic agents. To augment the proton relaxivity of agents derived from the heme domain of cytochrome P450 BM3 (BM3h), we formed manganese(III)-containing proteins that have higher electron spin than their native ferric iron counterparts. Metal substitution was achieved by coexpressing BM3h variants with the bacterial heme transporter ChuA in Escherichia coli and supplementing the growth medium with Mn3+-protoporphyrin IX. Manganic BM3h variants exhibited up to 2.6-fold higher T1 relaxivities relative to native BM3h at 4.7 T. Application of ChuA-mediated porphyrin substitution to a collection of thermostable chimeric P450 domains resulted in a stable, high-relaxivity BM3h derivative displaying a 63% relaxivity change upon binding of arachidonic acid, a natural ligand for the P450 enzyme and an important component of biological signaling pathways. This work demonstrates that protein-based MRI sensors with robust ligand sensitivity may be created with ease by including metal substitution among the toolkit of methods available to the protein engineer.National Institutes of Health (U.S.) (NIH Grant R01-DA28299 )National Institutes of Health (U.S.) (NIH NRSA Fellowship (Award F32-GM087102))California Institute of Technology (Caltech Jacobs Grant
Gravity, Lorentz Violation, and the Standard Model
The role of the gravitational sector in the Lorentz- and CPT-violating
Standard-Model Extension (SME) is studied. A framework is developed for
addressing this topic in the context of Riemann-Cartan spacetimes, which
include as limiting cases the usual Riemann and Minkowski geometries. The
methodology is first illustrated in the context of the QED extension in a
Riemann-Cartan background. The full SME in this background is then considered,
and the leading-order terms in the SME action involving operators of mass
dimension three and four are constructed. The incorporation of arbitrary
Lorentz and CPT violation into general relativity and other theories of gravity
based on Riemann-Cartan geometries is discussed. The dominant terms in the
effective low-energy action for the gravitational sector are provided, thereby
completing the formulation of the leading-order terms in the SME with gravity.
Explicit Lorentz symmetry breaking is found to be incompatible with generic
Riemann-Cartan geometries, but spontaneous Lorentz breaking evades this
difficulty.Comment: 21 pages REVTeX, references added, accepted in Physical Review
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