63 research outputs found

    ICONE12-49527 STUDY ON SIMULATION, CONTROL AND ONLINE ASSISTANCE INTEGRATED SYSTEM OF 10 MW HIGH TEMPERATURE GAS-COOLED TEST REACTOR

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    ABSTRACT In order to provide a convenient tool for engineering designed, safety analysis, operator training and control system design of the high temperature gas-cooled test reactor (HTR), an integrated system for simulation, control and online assistance of the HTR-10 has been designed and is still under development by the Institute of Nuclear Energy Technology (INET) of Tsinghua University in China. The whole system is based on a network environment and includes three subsystems: the simulation subsystem (SIMUSUB), the visualized control designed subsystem (VCDSUB) and the online assistance subsystem (OASUB). The SIMUSUB consists of four parts: the simulation calculating server (SCS), the main control client (MCC), the data disposal client (DDC) and the results graphic display client (RGDC), all of which can communicate each other via network. The SIMUSUB is intended to analyze and calculate the physical processes of the reactor core, the main loop system and the stream generator, etc., as well as to simulate the normal operation and transient accidents, and the result data can be graphically displayed through the RGDC dynamically. The VCDSUB provides a platform for control system modeling where the control flow systems can be automatically generated and graphically simulated. Based on the data from the field bus, the OASUB provides some of the reactor core parameter, which are difficult to measure. This whole system can be used as an educational tool to understand the design and operational characteristics of the HTR-10, and can also provide online supports for operators in the main control room, or as a convenient powerful tool for the control system design

    Enhancing Network Processor Simulation Speed with Statistical Input Sampling, ser

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    Abstract. While cycle-accurate simulation tools have been widely used in modeling high-performance processors, such an approach can be hindered by the increasing complexity of the simulation, especially in modeling chip multi-processors with multi-threading such as the network processors (NP). We have observed that for NP cycle level simulation, several days of simulation time covers only about one second of the real-world network traffic. Existing approaches to accelerating simulation are through either code analysis or execution sampling. Unfortunately, they are not applicable in speeding up NP simulations due to the small code size and the iterative nature of NP applications. We propose to sample the traffic input to the NP so that a long packet trace is represented by a much shorter one with simulation error bounded within ±3% and 95% confidence. Our method resulted one order of magnitude improvement in the NP simulation speed

    Reveal a hidden highly toxic substance in biochar to support its effective elimination strategy

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    With the aim to develop optimized biochar with minimal contaminants, it is important significance to broaden the understanding of biochar. Here, we disclose for the first time, a highly toxic substance (metal cyanide, MCN, such as KCN or NaCN) in biochar. The cyanide ion (CN−) content in biochar can be up to 85,870 mg/kg, which is determined by the inherent metal content and type in the biomass with K and Na increasing and Ca, Mg and Fe decreasing its formation. Density functional theory (DFT) analysis shows that unstable alkali oxygen-containing metal salts such as K2CO3 can induce an N rearrangement reaction to produce for example, KOCN. The strong reducing character of the carbon matrix further converts KOCN to KCN, thus resulting biochar with high risk. However, the stable Mg, Ca and Fe salts in biomass cannot induce an N rearrangement reaction due to their high binding energies. We therefore propose that high valent metal chloride salts such as FeCl3 and MgCl2 could be used to inhibit the production of cyanide via metal interactive reaction. These findings open a new point of view on the potential risk of biochar and provide a mitigation solution for biochar’s sustainable application

    Vitamin D and cause-specific vascular disease and mortality:a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults

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    An interlaboratory comparison of aerosol inorganic ion measurements by ion chromatography : Implications for aerosol pH estimate

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    Water-soluble inorganic ions such as ammonium, nitrate and sulfate are major components of fine aerosols in the atmosphere and are widely used in the estimation of aerosol acidity. However, different experimental practices and instrumentation may lead to uncertainties in ion concentrations. Here, an intercomparison experiment was conducted in 10 different laboratories (labs) to investigate the consistency of inorganic ion concentrations and resultant aerosol acidity estimates using the same set of aerosol filter samples. The results mostly exhibited good agreement for major ions Cl-, SO2-4, NO-3, NHC4 and KC. However, F-, Mg2C and Ca2C were observed with more variations across the different labs. The Aerosol Chemical Speciation Monitor (ACSM) data of nonrefractory SO2-4, NO-3 and NHC4 generally correlated very well with the filter-analysis-based data in our study, but the absolute concentrations differ by up to 42 %. Cl-from the two methods are correlated, but the concentration differ by more than a factor of 3. The analyses of certified reference materials (CRMs) generally showed a good detection accuracy (DA) of all ions in all the labs, the majority of which ranged between 90 % and 110 %. The DA was also used to correct the ion concentrations to showcase the importance of using CRMs for calibration check and quality control. Better agreements were found for Cl-, SO2-4, NO-3, NHC4 and KC across the labs after their concentrations were corrected with DA; the coefficient of variation (CV) of Cl-, SO2-4, NO-3, NHC4 and KC decreased by 1.7 %, 3.4 %, 3.4 %, 1.2 % and 2.6 %, respectively, after DA correction. We found that the ratio of anion to cation equivalent concentrations (AE/CE) and ion balance (anions-cations) are not good indicators for aerosol acidity estimates, as the results in different labs did not agree well with each other. In situ aerosol pH calculated from the ISORROPIA II thermodynamic equilibrium model with measured ion and ammonia concentrations showed a similar trend and good agreement across the 10 labs. Our results indicate that although there are important uncertainties in aerosol ion concentration measurements, the estimated aerosol pH from the ISORROPIA II model is more consistent

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Role of the 5′-Proximal Stem-Loop Structure of the 5′ Untranslated Region in Replication and Translation of Hepatitis C Virus RNA

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    Sequences of the untranslated regions at the 5′ and 3′ ends (5′UTR and 3′UTR) of the hepatitis C virus (HCV) RNA genome are highly conserved and contain cis-acting RNA elements for HCV RNA replication. The HCV 5′UTR consists of two distinct RNA elements, a short 5′-proximal stem-loop RNA element (nucleotides 1 to 43) and a longer element of internal ribosome entry site. To determine the sequence and structural requirements of the 5′-proximal stem-loop RNA element in HCV RNA replication and translation, a mutagenesis analysis was preformed by nucleotide deletions and substitutions. Effects of mutations in the 5′-proximal stem-loop RNA element on HCV RNA replication were determined by using a cell-based HCV replicon replication system. Deletion of the first 20 nucleotides from the 5′ end resulted in elimination of cell colony formation. Likewise, disruption of the 5′-proximal stem-loop by nucleotide substitutions abolished the ability of HCV RNA to induce cell colony formation. However, restoration of the 5′-proximal stem-loop by compensatory mutations with different nucleotides rescued the ability of the subgenomic HCV RNA to replicate in Huh7 cells. In addition, deletion and nucleotide substitutions of the 5′-proximal stem-loop structure, including the restored stem-loop by compensatory mutations, all resulted in reduction of translation by two- to fivefold, suggesting that the 5′-proximal stem-loop RNA element also modulates HCV RNA translation. These findings demonstrate that the 5′-proximal stem-loop of the HCV RNA is a cis-acting RNA element that regulates HCV RNA replication and translation

    Differentially private mechanisms for budget limited mobile crowdsourcing

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    Recently, Mobile Crowdsourcing (MC) has aroused great interest on the part of both academic and industrial circles. One of the key problems in MC is designing the proper mechanisms to incentivize user participation, as users are typically self-interested and must consume a substantial amount of MC resources/costs. Although considerable research has been devoted to this problem, the majority of studies have neglected the privacy issue in mechanism design. In this study, we consider the scenario where a mobile crowdsourcing platform aims to maximize the crowdsourcing revenue under a budget constraint, and users are interested in maximizing their utility while keeping their cost private. We design differentially-private mechanisms for such a scenario under an offline setting where users bid their costs simultaneously and under an online setting where user bids are revealed one by one. We show that our mechanisms simultaneously achieve provable performance bounds with respect to several measures, including revenue, differential privacy, truthfulness, and individual rationality. Finally, we also conduct extensive numerical experiments to demonstrate the effectiveness of our approach.Accepted versio

    Mullite Reinforced SiC/Al2O3 Composites Prepared by Microwave Sintering Based on Green Manufacturing

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    In the preparation process of composites, the implementation of green manufacturing technology has an important impact on improving material properties and preparation efficiency. The adopting of green manufacturing technology not only greatly reduces the energy consumption but also effectively avoids the environmental pollution. Compared with the traditional material preparation process, the material preparation process for green manufacturing is a new concept and idea. Microwave sintering is such an efficient, clean, and pollution-free preparation process, so it is widely used in the field of material preparation. By microwave sintering, the mullite reinforced SiC/Al2O3 composites with different SiC particle size were prepared from the composite powders composed of SiC particles coated with SiO2, by a sol-gel method and Al2O3 particles. The effect of SiC particle size on the microstructure, bulk density, fracture toughness, flexural strength, and thermal shock resistance of SiC/Al2O3 composites was studied. The bulk density, fracture toughness, and flexural strength were evaluated by the Archimedes method, single-side notched beam method, and three-point bending method, respectively. The thermal shock resistance of samples was investigated through the combination of water quenching and three-point bending methods. The results showed that with the increase of SiC particle size, the bulk density, fracture toughness, and flexural strength of samples all increased first and then decreased. The bulk density, fracture toughness, flexural strength, and flexural strength retention of SiC(5 μm)/Al2O3 composites were better than those of other samples, which were 2.06 g/cm3, 1.98 MPa·m1/2, 63 MPa, and 60%, respectively. The better mechanical properties and thermal shock resistance of SiC(5 μm)/Al2O3 composites are due to the formation of bridging mullite whiskers between SiC and Al2O3 particles with large length diameter ratio. Therefore, the unique sintering mechanisms of size coupling effect and local thermal aggregation effect in microwave sintering were discussed. The research results can not only provide reference for the preparation process of mullite reinforced SiC/Al2O3 composites but also for the wide application of microwave sintering technology
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