8 research outputs found
Surface Roughness Effect on Discharge Coefficient of Combined Cylindrical Weir Gate Structure
The aim of this research is to investigate the effect of surface roughness on the performance of weir and gate. An experimental study in a laboratory flume is carried out to study flow over and under cylindrical weir gate in combined structure as flow measurement device. Four models having different diameters were tested in a laboratory flume. In each model, the surface was roughed four times. The results of the test show logical negative effect of the increase of surface roughness on the performance. The performance of the combined structure improved with decrease ratio of roughness to the upstream head (Ks/H) and with the increase of the total head to the diameter of the weir (H/d). Empirical relations were obtained to estimate the variation of discharge coefficient (Cd) in terms of some dimensionless parameters. Within the limitations of the present experimental work an equation to predict the discharge is proposed with R2 of 0.936. Finely the contribution of the gate increases relative to the weir when the surface roughness increases
Properties of Flow through and over Gravel Basket Weir
يؤدي إنشاء هدارات من سلال الحصى في المجاري المائية إلى تراكم المياه أمام هذه المشأت المسامية، ويكون فيها منسوب المياه أقل من تلك التي تتجمع مقدمة الهدارات الصلبة. تتضمن هذه الدراسة، تقديرعمق الماء المتجمع امام هذه الهدارات مع قياس شكل السطح الحر للجريان والتنبؤ بقيمة معامل التصريف من خلال التجارب المختبرية. كما تمت دراسة أربعة أطوال مختلفة من الهدارات (15 ، 20 ، 25 و 30 سم) وأربع خشونات مختلفة من الحصى (1.13 ، 1.58 ، 2.19 و 2.27). وفقًا لذلك، فقد تم اختبارستة عشر نموذجاً في ظروف مختلفة من التدفق الحر. أظهرتحليل نتائج نظام الجريان "التدفق النافذ" أن الزيادة في عرض السد تسبب في زيادة عمق الماء المتجمع امام الهدارات ولجميع درجات الخشونة بنسبة 30٪ بينما تقلل الخشونة من العمق بنسبة 28٪. وفي "التدفق الانتقالي"، يؤدي مضاعفة الطول إلى زيادة عمق التدفق بنسبة 7٪، بينما تؤدي زيادة الخشونة من 1.13 إلى 2.72 سم في انخفاض عمق الجريان بنسبة 7٪. يبدأ نظام "التدفق الفائض" بالظهورعندما تساوي نسبة عمق الماء إلى عرض السد حوالي 0.75 للعرض الكبير و1.54 للعرض القليل. تشير المقارنة بين هدارات سلال الحصى والهدارات الصلبة إلى أن متوسط تقليل عمق الماء هو 7.5٪ للصلابة البالغة 1.13 سم و9٪ للصلابة البالغة 2.72 سم. تم اقتراح نماذج رياضية للتنبؤ بعمق المياه لأنظمة التدفق الثلاثة، أما بالنسبة لنظام "التدفق الفائض"، فقد اقتُرِحَت صيغة تجريبية لتقدير معامل التصريف بدقة مقبولة.Construction of gravel basket weir in waterways causes water accumulation in front of this porous structure less than solid weir. In the present study the upstream flow depth, water surface profile and discharge coefficient are investigated through laboratory experiments. Four different weir lengths (15, 20, 25 and 30 cm) and four different degrees of gravel coarseness (1.13, 1.58, 2.19 and 2.27) are studied. Accordingly, sixteen models are tested under different free flow conditions. Analysis of the results show that in "through flow" regime the increase in weir length raises the generated upstream depth for all coarseness degrees by 30% while coarseness lowers the depth by 28%. In "transition flow", however, doubling the length increases the flow depth by 7%, but increasing coarseness from 1.13 to 2.72 cm mean diameter causes 7% reduction in flow depth. The "overflow" regime begins to appear when the depth to length ratio equals 0.75 for long weir, and about 1.54 for shortest weir. A comparison between gravel basket weir and corresponding solid weir indicates that average depth reduction is 7.5% for coarseness of 1.13 cm and 9% for coarseness of 2.72 cm. Mathematical models for water depth prediction for the three flow regimes are presented. For "overflow" an empirical formula is proposed to estimate the coefficient of discharge with acceptable accuracy
Effect of Prismatic Sill on the Performance of Free Flow under Sluice Gate
Sills under sluice gates is used in hydraulic structures; their effect on the head generated upstream gates for certain rate of flow is related to the height and length of sill. A study is held in laboratory flume on four different prismatic sill heights and one model without sill by changing the gate opening four times for each model. Statistical analyses on the dimensionless physical quantities are done. A positive effect of sill on the performance of flow is noted by increasing the flow rate up to 25% for some models. The coefficient of discharge decreases with increase of relative sill height to the head upstream and increases with three other dimensionless parameters. The relative sill height to the gate opening shows the highest correlation factor with the discharge coefficient and its positive effect on the flow phenomena is 55.4%. Within the experimental measures limitations, a linear equation for predicting the discharge coefficient is proposed with Adj. R2 0.923
Research Article Surface Roughness Effects on Discharge Coefficient of Broad Crested Weir
Abstract: The aim of this study is to investigate the effects of surface roughness sizes on the discharge coefficient for a broad crested weirs. For this purpose, three models having different lengths of broad crested weirs were tested in a horizontal flume. In each model, the surface was roughed four times. Experimental results of all models showed that the logical negative effect of roughness increased on the discharge (Q) for different values of length. The performance of broad crested weir improved with decrease ratio of roughness to the weir height (Ks/P) and with the increase of the total Head to the Length (H/L). An empirical equation was obtained to estimate the variation of discharge coefficient C d in terms total head to length ratio, with total head to roughness ratio
Hydraulic Performance for Combined Weir-Gate Structure
Combined hydraulic structure play an important role in controlling flow in open channels. This study was based on experimental and numerical modeling investigations for combined hydraulic structure. For this purpose three physical models of combined sharp crested trapezoidal weir with bottom opening and one physical model of sharp crested trapezoidal weir separately were used and tested by running eight different flow rates over each model. In which three configurations of bottom opening were tested; the first configuration is a rectangular gate while other two configuration were trapezoidal with two different side slopes of (1V:4H) and (1V:2H). The water surface profiles passing through weir-gate system were measured for all thirty two runs of all models which show uniform flow at 2.11h from the upstream of weir. The commercial computational fluid dynamic software ANSYS CFX was used to simulate flow numerically. The verification of the numerical model was based on water surface profiles and discharge which showed acceptable agreement. Also, the results showed that discharge coefficient Cd varies from (0.52-0.58). Furthermore, it was shown that both models with trapezoidal gate pass a higher discharge of flow than the model with rectangular gate with average percentage increase of discharge (40.78% and 19.40%) for trapezoidal side slopes (1H:2V and 1H:4V) respectively. In addition, the combined system with milder trapezoidal side slopes of bottom opening had a better performance for discharging weir flow which is about 40% as compared with traditional one. Finally, the empirical equations for stage-discharge relationship were estimated for all models and discharge coefficients were estimated for all runs
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Summary
Background
The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories.
Methods
In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors.
Findings
Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths.
Interpretation
The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research