49 research outputs found

    A KD framework in football data analytics: a value co-creation framework for the use of knowledge discovery technologies in the football industry

    Get PDF
    Investment in sport technologies are expected to grow by 40.1% during 2016-2022 reaching approximately $3.97 billion by 2022. As well the recent changes in technology regulations by The Federation Internationale de Football Association (FIFA) since the 2018 World Cup created promising football technologies. This research questions addressing the issue of what is the value of such technologies for professional football teams? and what are the benefits of these technologies? This is achieved by developing a framework for understanding the value co-creation process from the knowledge discovery systems in the football industry. The framework aids in mapping the resources, pinpointing the outputs, identifying the competencies leading into capabilities, and finally in realisation of the value of the final outcomes in that journey. On another words, different teams have different resources that allow them to achieve certain outputs. These outputs enable the coaching team to achieve and maintain certain abilities. By changes in practice the will improve the team ability and enhance their analytical capabilities. Therefore, that will allow and aid the coaching team to gain new outcomes such as improving training strategies, transferring players, and informative match strategies. Additionally, improved understanding of the value co-creation process from the knowledge discovery systems in the football industry answering, why are some teams better able to gain value from investment in knowledge discovery technologies than other teams in the football industry. The framework has been developed in three phases in which semi-structured interviews where used in the first and second phases for developing and validating the framework respectively. The third and final phases is verifying the framework by developing a knowledge discovery maturity model as an online assessment s tool in operationalising the research findings. The main contributions of this research are the adaptation and customisation of Melville et al. (2004) to develop a value co-creation process form knowledge discovery resources. Moreover, applying Agile (APM, 2015) artefacts and techniques and tools in improving the value co-creation process between coaches and data analysts. That s aided in developing the value co-creation knowledge discovery framework in football analytics. Additionally, the development of a key performance indicators balanced scorecard and its adaptation as a in understanding the relationships between the key performance indicators (i.e. physical, psychological, technical and tactical performance indicators). Finally, the development of the knowledge discovery maturity model in football analytics which was used in understanding and pinpointing areas of strength and weakness in the utilisation of the various football resources used in football analytics (human resources, technological resources, value co-creation resources and analytical models used)

    L-Tryptophan and Thiamine Hydrochloride as Vital Factors of the Indole Acetic Acid and Siderophores Produced by Rhizobium leguminosarum bv. viceae and Their reflection on Faba Bean growth Yield and some Soil Properties under Saline Soil

    Get PDF
    Plant growth promoting rhizobacteria such as R. leguminosarum bv. viceae strains no. 481 & 441 were shown to produce indole-3-acetic acid (IAA) and siderophores in bacterial culture supplemented with L-tryptophan (L-trp) and thiamine hydrochloride (Thch) concentrations. Maximum IAA production was found in the medium amended with 1.5mg ml-1 (L-trp). IAA production was not observed with the (L-trp) in free medium while (Thch) produced a maximum amount of growth and IAA at 3 mg ml-1 for both the two rhizobial strains. Biosynthesis of siderophore was maximum (44.23% and 35.75%) at 1.5mg ml-1 of (L-trp ) while the production of sidrophore was (40.49% & 34.68 % of siderophore units) at 3 mg ml-1 of (Thch) in R. leguminosarum bv. viceae strain 481 & 441 respectively. Rhizobial strain 481 was more active in the production IAA and siderophore than the other rhizobial strain 441. A field experiment on a newly reclaimed saline soil at Sahl El-Hussinia, El-Sharkia Governorate, Egypt, used to evaluate the effect of IAA and siderophores synthesizing by rhizobial strains on plant growth parameters and soil characteristics. The obtained results revealed that applying of rhizobial strains grown on 1.5mg ml-1 L-Trp and 3 mg ml-1 (Thch) led to improve soil properties which reflected on the crop growth and yield components. Soil respiration (CO2 evolution) and proline content were also studied

    Effect of the pre-magnetic treatment of seeds and the N-fertilizer on the yield and quality of groundnut grown in sandy soil

    Get PDF
    This field trial aimed to study the effect of the magnetic treatment (MT) of urea as a nitrogen (N) fertilizer as well as the MT of the groundnut (Arachis hypogaea L.) seeds before sowing on the crop yield and quality under sandy soil conditions during the summer seasons of 2020 and/or 2021. Treatments were distributed in a split-plots design in triplicates. The control CL has received the recommended dose RD of the N-fertilizer while other treatments received the rates 50, 75, and 100% of the RD as magnetized urea (main factor F1) applied to the surface soil. The sub-factor (F2) was the time of MT (15, 30, and 45 min) of the groundnut seeds exposed to magnetic field MF 1.4 T before planting. Representative samples from the soil and plant were taken after harvesting. At the 15-min time and 100% N-fertilization, the yield of pods and seeds (kg ha-1) has increased relatively by 8.2% and 9.7% respectively, compared to the corresponding CL. At the 30-min time and 50% and 100% N-fertilization, the yield (kg ha-1) has increased relatively by 9.7% and 13.3% respectively for pods and by 10.1% and 16.8% respectively for the seeds. At the 45-min time and 50% N-fertilization, the yield (kg ha-1) has increased by 12.4% and 14.6% for pods and seeds, respectively. The 100% N-fertilization along with 15 min MT before cultivation or the 50% and/or 100% N-fertilization along with 30 min MT or the 50% along with 45 min MT could be recommended. The agronomic efficiency (AE) for the N, P, and K nutrients was increased by the MT in the order 15 min < 30 min < 45 min at the 50, 75, and 100% N-fertilization rates

    An Approach to Mining Picture Objects Based on Textual Cues

    Get PDF
    Abstract. The task of extracting knowledge from text is an important research problem for information processing and document understanding. Approaches to capture the semantics of picture objects in documents constitute subjects of great interest in the domain of document mining recently. In this paper, we present an approach to extracting information about picture objects in a document using cues from the text written about them. The goal of this work is to mine a document and understand the content of picture objects in the document based on meaning inferred from the texts written about such objects. We apply some Natural Language Processing techniques to extract semantic information about picture objects in a document and process texts written about them. The mining algorithms were developed and implemented as a working system and gone through testing and experimentations. Results and future extensions of the work are discussed in this paper

    Effect of pre-sowing magnetic treatment of seeds with bio- and mineral fertilization on the soybean cultivated in a saline calcareous soil

    Get PDF
    Bio-farming is an eco-friendly advance that minimizes the required chemical additives for optimizing the quality of crops that their storage is often accompanied by seeds’ components degradation. Magnetic treatment of seed was considered as a promising tool improves germination and growth. This study aims to evaluate the effect of individual and combined application of bio-fertilizers and the N-P-K mineral fertilizers preceded by magnetic treatment of dry and/or water-soaked seeds before sowing on the yield and quality of soybean cultivated in a saline soil.The field experiment was carried out in a split-split plot design with triplicates. The main two factors (F1) were not bio-fertilized and bio-fertilized plots. The sub-factors (F2) were three application rates (A: 50%, B: 75%, and C: 100%) of recommended doses of the three N, P, K fertilizers. The sub-sub factors (F3) were seeds not magnetically treated (NM) and magnetically treated (M). All factors were studied for dry soybean seeds (without soaking) and soaked seeds in magnetically treated water. After harvesting, soil and plant samples were analyzed. The most significant increase in the soybean seed yield (kg ha-1) was by 49.98% for the bio-fertilized magnetized dry seeds at 75% and 100% mineral N-P-K fertilization compared with the NM soaked seeds at 50% N-P-K (A rate) without bio-fertilization. The 75% mineral fertilization significantly increased the protein (%) by 41.69% and decreased the proline (mg g-1dw) by 46.68%. Magnetic treatment of seeds before cultivation and combined bio/mineral N-P-K fertilization reduced the Proline that alleviats the stress conditions

    3D extrusion printing of high drug loading immediate release paracetamol tablets

    Get PDF
    The manufacture of immediate release high drug loading paracetamol oral tablets was achieved using an extrusion based 3D printer from a premixed water based paste formulation. The 3D printed tablets demonstrate that a very high drug (paracetamol) loading formulation (80% w/w) can be printed as an acceptable tablet using a method suitable for personalisation and distributed manufacture. Paracetamol is an example of a drug whose physical form can present challenges to traditional powder compression tableting. Printing avoids these issues and facilitates the relatively high drug loading. The 3D printed tablets were evaluated for physical and mechanical properties including weight variation, friability, breaking force, disintegration time, and dimensions and were within acceptable range as defined by the international standards stated in the United States Pharmacopoeia (USP). X-Ray Powder Diffraction (XRPD) was used to identify the physical form of the active. Additionally, XRPD, Attenuated Total Reflectance Fourier Transform Infrared spectroscopy (ATR-FTIR) and differential scanning calorimetry (DSC) were used to assess possible drug-excipient interactions. The 3D printed tablets were evaluated for drug release using a USP dissolution testing type I apparatus. The tablets showed a profile characteristic of the immediate release profile as intended based upon the active/excipient ratio used with disintegration in less than 60 seconds and release of most of the drug within 5 minutes. The results demonstrate the capability of 3D extrusion based printing to produce acceptable high-drug loading tablets from approved materials that comply with current USP standards

    3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

    Get PDF
    We have used three dimensional (3D) extrusion printing to manufacture a multi-active solid dosage form or so called polypill. This contains five compartmentalised drugs with two independently controlled and well-defined release profiles. This polypill demonstrates that complex medication regimes can be combined in a single personalised tablet. This could potentially improve adherence for those patients currently taking many separate tablets and also allow ready tailoring of a particular drug combination/drug release for the needs of an individual. The polypill here represents a cardiovascular treatment regime with the incorporation of an immediate release compartment with aspirin and hydrochlorothiazide and three sustained release compartments containing pravastatin, atenolol, and ramipril. X-ray powder diffraction (XRPD) and Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR) were used to assess drug-excipient interaction. The printed polypills were evaluated for drug release using USP dissolution testing. We found that the polypill showed the intended immediate and sustained release profiles based upon the active/excipient ratio used

    Extrusion 3D printing of paracetamol tablets from a single formulation with tunable release profiles through control of tablet geometry

    Get PDF
    An extrusion based 3D printer was used to fabricate paracetamol tablets with different geometries (mesh, ring, and solid) from a single paste-based formulation formed from standard pharmaceutical ingredients. The tablets demonstrate that tunable drug release profiles can be achieved from this single formulation even with high drug loading (>80% w/w). The tablets were evaluated for drug release using a USP dissolution testing type I apparatus. The tablets showed well-defined release profiles (from immediate to sustained release) controlled by their different geometries. The dissolution results showed dependency of drug release on the surface area/volume (SA/V) ratio and the SA of the different tablets. The tablets with larger SA/V ratios and SA had faster drug release. The 3D printed tablets were also evaluated for physical and mechanical properties including tablet dimension, drug content, weight variation, breaking force and were within acceptable range as defined by the international standards stated in the United States Pharmacopoeia. X-Ray Powder Diffraction, Differential Scanning Calorimetry, and Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy were used to identify the physical form of the active and to assess possible drug-excipient interactions. These data again showed that the tablets meet USP requirement. These results clearly demonstrate the potential of 3D printing to create unique pharmaceutical manufacturing, and potentially clinical, opportunities. The ability to use a single unmodified formulation to achieve defined release profiles could allow, for example, relatively straightforward personalization of medicines for individuals with different metabolism rates for certain drugs and hence could offer significant development and clinical opportunities

    A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants

    Get PDF
    We propose a strategy for creating tuneable 3D printed drug delivery devices. 3D printing offers the opportunity for improved compliance and patient treatment outcomes through personalisation, but bottlenecks include finding formulations that provide a choice of drug loading and release rate, are tuneable and avoid the need for surgical removal. Our solution is to exploit 3D inkjet printing freedoms. We use a reactive prodrug that can polymerize into drug-attached macromolecules during 3D printing, and by tuning the hydrophilicity we can facilitate or hinder hydrolysis, which in turn controls the drug release. To demonstrate this approach, we attach ibuprofen to 2-hydroxyethyl acrylate through a cleavable ester bond, formulate it for inkjet 3D printing, and then print to produce a solid dosage form. This allows a much higher loading than is usually achievable-in our case up to 58 wt%. Of equal importance, the 3D inkjet printing freedoms mean that our drug delivery device is highly tuneable: by selection of spacer monomers to adjust the hydrophilicity; through geometry; by spatially varying the components. Consequently, we create bespoke, hierarchical release systems, from the molecular to macro. This approach represents a new paradigm for the formulation of printable inks for drug-loaded medical devices

    Extrusion 3D printing of paracetamol tablets from a single formulation with tunable release profiles through control of tablet geometry

    Get PDF
    An extrusion based 3D printer was used to fabricate paracetamol tablets with different geometries (mesh, ring, and solid) from a single paste-based formulation formed from standard pharmaceutical ingredients. The tablets demonstrate that tunable drug release profiles can be achieved from this single formulation even with high drug loading (>80% w/w). The tablets were evaluated for drug release using a USP dissolution testing type I apparatus. The tablets showed well-defined release profiles (from immediate to sustained release) controlled by their different geometries. The dissolution results showed dependency of drug release on the surface area/volume (SA/V) ratio and the SA of the different tablets. The tablets with larger SA/V ratios and SA had faster drug release. The 3D printed tablets were also evaluated for physical and mechanical properties including tablet dimension, drug content, weight variation, breaking force and were within acceptable range as defined by the international standards stated in the United States Pharmacopoeia. X-Ray Powder Diffraction, Differential Scanning Calorimetry, and Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy were used to identify the physical form of the active and to assess possible drug-excipient interactions. These data again showed that the tablets meet USP requirement. These results clearly demonstrate the potential of 3D printing to create unique pharmaceutical manufacturing, and potentially clinical, opportunities. The ability to use a single unmodified formulation to achieve defined release profiles could allow, for example, relatively straightforward personalization of medicines for individuals with different metabolism rates for certain drugs and hence could offer significant development and clinical opportunities
    corecore