Body dissatisfaction, appearance investment and wellbeing: how older obese men orient to 'aesthetic health' [forthcoming]

Most research on male body image to date has focused on young men using quantitative methods. The study reported here is based on qualitative interviews with a sample of older men (n = 30) on a weight management programme, and we asked them about body-related feelings. The interviews were all transcribed and analysed using thematic analysis. Our results indicate that although body weight was typically minimised, body image was a key concern, with many examples of body consciousness and body dissatisfaction evident. On the other hand, post-programme weight loss was associated with a transformative shift in body image, with the men emphasising enhanced body confidence, self-esteem and psychological wellbeing. We conclude by highlighting the need to recognise and address appearance issues and/as health concerns for middle-aged and older men

Patterns of contribution to citizen science biodiversity projects increase understanding of volunteers’ recording behaviour

The often opportunistic nature of biological recording via citizen science leads to taxonomic, spatial and temporal biases which add uncertainty to biodiversity estimates. However, such biases may also give valuable insight into volunteers’ recording behaviour. Using Greater London as a case-study we examined the composition of three citizen science datasets – from Greenspace Information for Greater London CIC, iSpot and iRecord - with respect to recorder contribution and spatial and taxonomic biases, i.e. when, where and what volunteers record. We found most volunteers contributed few records and were active for just one day. Each dataset had its own taxonomic and spatial signature suggesting that volunteers’ personal recording preferences may attract them towards particular schemes. There were also patterns across datasets: species’ abundance and ease of identification were positively associated with number of records, as was plant height. We found clear hotspots of recording activity, the 10 most popular sites containing open water. We note that biases are accrued as part of the recording process (e.g. species’ detectability) as well as from volunteer preferences. An increased understanding of volunteer behaviour gained from analysing the composition of records could thus enhance the fit between volunteers’ interests and the needs of scientific projects

Food assessment: a discursive analysis of diet talk in interviews with older men who are obese

Objective: Obesity rates are increasing faster in men than in women, with particular concerns raised regarding older men. However, men are less likely than women to engage in weight-loss activities such as dieting, typically constructed as a feminine practice. Previous research has argued that men’s food consumption is notably different and unhealthier than women’s. The novel contribution of this article is an analysis of food assessments in order to explore how older men (mostly) undergoing weight management programmes make sense of changes in their nutritional intake. Design: Semi-structured interviews were conducted with 30 men who were obese, 27 of whom were engaged in weight loss programmes. Discursive psychology was employed to analyse the data. Results: In contrast to other research, participants constructed nutritional advice as enlightening. Participants worked up ‘ownership’ and pleasure assessments to certain food choices which they contrasted with new, less calorific, eating practices. Moreover, new diets were constructed as acceptable. Conclusion: Our study contributes new insights about how nutritional advice impacts upon preconceived (mis)understandings of healthy eating practices. During the interviews, men positioned themselves as educators – health promoters might usefully develop nutritional advice in collaboration with men who have successfully changed their diets for optimum effect

Evolving Industry Partnerships and Investments in Cell and Gene Therapies

Cell and gene therapies hold the promise of providing significant and durable health gains to patients in many disease states and have recently elicited significant investor and partner interest. We cover the current state of industry partnerships and investments, highlight what makes a partnership advantageous, and discuss implications for stem cell therapies

Quantifying the anisotropy in the infrared emission of powerful AGN

We use restframe near- and mid-IR data of an isotropically selected sample of quasars and radio galaxies at 1.0 \leq z \leq 1.4, which have been published previously, to study the wavelength-dependent anisotropy of the IR emission. For that we build average SEDs of the quasar subsample (= type 1 AGN) and radio galaxies (= type 2 AGN) from ~1-17 {\mu}m and plot the ratio of both average samples. From 2 to 8 {\mu}m restframe wavelength the ratio gradually decreases from 20 to 2 with values around 3 in the 10{\mu}m silicate feature. Longward of 12{\mu}m the ratio decreases further and shows some high degree of isotropy at 15 {\mu}m (ratio ~1.4). The results are consistent with upper limits derived from the X-ray/mid-IR correlation of local Seyfert galaxies. We find that the anisotropy in our high-luminosity radio-loud sample is smaller than in radio-quiet lower-luminosity AGN which may be interpreted in the framework of a receding torus model with luminosity-dependent obscuration properties. It is also shown that the relatively small degree of anisotropy is consistent with clumpy torus models.Comment: 6 pages, 2 figures; accepted by Ap

Revisiting the WMAP - NVSS angular cross correlation. A skeptic's view

In the context of the study of the ISW, we revisit the angular cross correlation of WMAP CMB data with the NVSS radio survey. We compute 2-point cross functions between the two surveys in real and in Fourier space, paying particular attention on the dependence of results on the flux of NVSS radio sources, the angular scales where correlations arise and the comparison with theoretical expectations. We reproduce previous results that claim an excess of correlation in the angular correlation function (ACF), and we also find some (low significance) similarity between the CMB and radio galaxy data in the multipole range \el \in [10, 25]. However, the S/N in the ACFs increases with higher flux thresholds for NVSS sources, but drops a $\sim$ 30 - 50% in separations of the order of a pixel size, suggesting some residual point source contribution. When restricting our analyses to multipoles \el \gt 60, we fail to find any evidence for cross correlation in the range \el \in [2,10], where according to the model predictions and our simulations $\sim$ 50% of the S/N is supposed to arise. Also, the accumulated S/N for \el \lt 60 is below 1, far from the theoretical expectation of S/N$\sim 5$. Part of this disagreement may be caused by an inaccurate modeling of the NVSS source population: as in previous works, we find a level of large scale (\el \lt 70) clustering in the NVSS catalog that seems incompatible with a high redshift population. This is unlikely to be caused by contaminants or systematics, since it is independent of flux threshold, and hence present for the brightest ($\gt 30 \sigma$) NVSS sources. Either our NVSS catalogs are not probing the high redshift, large scale gravitational potential wells, or there is a clear mismatch between the ISW component present in WMAP data and theoretical expectations.Comment: 16 pages, one extra figure (13 total), matches accepted version in A&

Substrate Type Determines Metagenomic Profiles from Diverse Chemical Habitats

Environmental parameters drive phenotypic and genotypic frequency variations in microbial communities and thus control the extent and structure of microbial diversity. We tested the extent to which microbial community composition changes are controlled by shifting physiochemical properties within a hypersaline lagoon. We sequenced four sediment metagenomes from the Coorong, South Australia from samples which varied in salinity by 99 Practical Salinity Units (PSU), an order of magnitude in ammonia concentration and two orders of magnitude in microbial abundance. Despite the marked divergence in environmental parameters observed between samples, hierarchical clustering of taxonomic and metabolic profiles of these metagenomes showed striking similarity between the samples (>89%). Comparison of these profiles to those derived from a wide variety of publically available datasets demonstrated that the Coorong sediment metagenomes were similar to other sediment, soil, biofilm and microbial mat samples regardless of salinity (>85% similarity). Overall, clustering of solid substrate and water metagenomes into discrete similarity groups based on functional potential indicated that the dichotomy between water and solid matrices is a fundamental determinant of community microbial metabolism that is not masked by salinity, nutrient concentration or microbial abundance.</p

Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over : a randomised controlled trial

Background: Observational studies have frequently reported an association between cognitive function and nutrition in later life but randomised trials of B vitamins and antioxidant supplements have mostly found no beneficial effect. We examined the effect of daily supplementation with 11 vitamins and 5 minerals on cognitive function in older adults to assess the possibility that this could help to prevent cognitive decline. Methods: The study was carried out as part of a randomised double blind placebo controlled trial of micronutrient supplementation based in six primary care health centres in North East Scotland. 910 men and women aged 65 years and over living in the community were recruited and randomised: 456 to active treatment and 454 to placebo. The active treatment consisted of a single tablet containing eleven vitamins and five minerals in amounts ranging from 50–210 % of the UK Reference Nutrient Intake or matching placebo tablet taken daily for 12 months. Digit span forward and verbal fluency tests, which assess immediate memory and executive functioning respectively, were conducted at the start and end of the intervention period. Risk of micronutrient deficiency at baseline was assessed by a simple risk questionnaire. Results: For digit span forward there was no evidence of an effect of supplements in all participants or in sub-groups defined by age or risk of deficiency. For verbal fluency there was no evidence of a beneficial effect in the whole study population but there was weak evidence for a beneficial effect of supplementation in the two pre-specified subgroups: in those aged 75 years and over (n 290; mean difference between supplemented and placebo groups 2.8 (95% CI -0.6, 6.2) units) and in those at increased risk of micronutrient deficiency assessed by the risk questionnaire (n 260; mean difference between supplemented and placebo groups 2.5 (95% CI -1.0, 6.1) units). Conclusion: The results provide no evidence for a beneficial effect of daily multivitamin and multimineral supplements on these domains of cognitive function in community-living people over 65 years. However, the possibility of beneficial effects in older people and those at greater risk of nutritional deficiency deserves further attention.Peer reviewedPublisher PD