23 research outputs found

    GA4GH: International policies and standards for data sharing across genomic research and healthcare.

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    The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic sequencing (along with other genome-wide molecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions of humans, with increasing levels of diversity. In this perspective, we present the GA4GH strategies for addressing the major challenges of this data revolution. We describe the GA4GH organization, which is fueled by the development efforts of eight Work Streams and informed by the needs of 24 Driver Projects and other key stakeholders. We present the GA4GH suite of secure, interoperable technical standards and policy frameworks and review the current status of standards, their relevance to key domains of research and clinical care, and future plans of GA4GH. Broad international participation in building, adopting, and deploying GA4GH standards and frameworks will catalyze an unprecedented effort in data sharing that will be critical to advancing genomic medicine and ensuring that all populations can access its benefits

    AN ASSESSMENT OF THE COMPETITIVE POSITION OF GREAT LAKES PORTS IN THE INTERNATIONAL STEAM COAL MARKET

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    This report, using a linear programming model to minimize total delivered world steam coal costs, analyzes future coal trade flows. Assessing the possibility of exporting Northern Great Plains coal through the St. Lawrence via the twin ports of Duluth, Minnesota and Superior, Wisconsin is the main goal of the study. World steam coal trade flows are projected for the years 1985, 1990 and 2000 through the linear programming model. The model includes demand from 25 coal importing nations and supply from 19 coal producing regions around the world

    AN ASSESSMENT OF THE COMPETITIVE POSITION OF GREAT LAKES PORTS IN THE INTERNATIONAL STEAM COAL MARKET

    No full text
    This report, using a linear programming model to minimize total delivered world steam coal costs, analyzes future coal trade flows. Assessing the possibility of exporting Northern Great Plains coal through the St. Lawrence via the twin ports of Duluth, Minnesota and Superior, Wisconsin is the main goal of the study. World steam coal trade flows are projected for the years 1985, 1990 and 2000 through the linear programming model. The model includes demand from 25 coal importing nations and supply from 19 coal producing regions around the world.Resource /Energy Economics and Policy,
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