UKRAINIAN-RUSSIAN CONFLICT IN THE DONBAS FROM THE POINT OF VIEW OF WESTERN HISTORIOGRAPHY: CHARACTER, ORIGINS, REASONS

Object of research: analysis of the works of modern foreign authors, which reflect the process of the Russian-Ukrainian conflict in the Donbas, which cast doubt on the European security system, has complicated the lives of millions of citizens. Clarification of the reasons that led to the amorphous national identity of the population of Donbas, rejection of Western values, mythical ideas about fascists-Banderites. Disclosure of the diversity of assessments of Western historiography regarding the origins and causes of the conflict, its nature. From a critical point of view, the work of "geopolitical realists" who are trying to minimize the Kremlin’s actions in relation to Ukraine is considered. Investigated problem: to show and prove that the revival of Russian neo-imperialism, which even after 1991 considered Ukraine a vassal, became the main external factor that led to the escalation of the conflict and its actual “freezing”. The attention is focused on the reasons for the appearance of peculiar stereotypes of thinking and behavior of residents of the Donetsk basin, contrasted with the mentality of citizens of other regions, especially Western Ukraine. The cultural-historical split of Ukraine, which developed historically, could not be the cause of the armed conflict, even with the pole opposition “Lviv-Donetsk”. Therefore, the separatist sentiments that appeared in Donbas at certain times were not a mass phenomenon even in 2014 because of this, it is impossible to explain Russian aggravation of relations between the elites of Kyiv and Donbas without analyzing external interference. The state of affairs was also aggravated by both sabotage of the Donbas elites, they did not recognize the legitimacy of the new government in Kyiv after February 2014, and by the mistakes made by the central government in Kyiv. Hasty and ill-conceived, according to Western experts, was the adoption by the Verkhovna Rada of Ukraine of a law abolishing the regional status of the Russian language. The name of the military operations from the Kyiv side as “anti-terrorist operation” was doubtful. It was changed late. Main scientific results: in fact, for the first time in the historiography of Ukraine, the latest works of Western scholars on the Ukrainian-Russian conflict have been analyzed. Conclusions are made about the inconsistency of the views of Western historians regarding the nature and causes of the conflict, the prospects for its settlement

PECULIAIRITIES OF THE INFLUENCE NITROGEN MONOXIDE SYNTHESIS BLOCKADE ON CIRCADIAN ORGANIZATION OF KIDNEY ACID-REGULATING FUNCTION UNDER CONDITIONS OF PINEAL GLAND HYPERFUNCTION

Introduction: In recent decades chronobiology - a science that studies the regularities of the functioning of the organism, especially biological rhythms is developing rapidly. Biorhythms are stable nonstopper lifetime fluctuations with individual amplitude-frequency characteristics. Kidneys are characterized by a clear time organization of functions too, however, the peculiarities of circadian organization and the mechanisms of the participation of intracellular messengers in particular nitrogen monoxide (NО) in biorhythmic regulation of renal functions, remain insufficiently studied The aim of our work was to investigate the peculiairities of the influence nitrogen monoxide synthesis blockade on circadian organization of kidney acid-regulating function under conditions of pineal gland hyperfunction. Materials and methods: The experiments were conducted on 72 mature non-linear albino male rats with their body mass 0,15-0,18 kg. The animals were kept under vivarium conditions at a stable temperature and air humidity fed on a standard dietary intake. The control group included animals (n=36) kept under conditions of usual light regimen (12.00L:12.00D) during 7 days. The experimental group included animals (n=36) injected with N-nitro-L-arginine (L-NNA) in the dose of 20 mg/kg during 7 days under conditions of continuous absolute darkness (12.00D:12.00D). On the 8th day the animals were exposed to 5% water load with heated to room temperature water supplied and the parameters of the kidney acid-regulating function under conditions of forced diuresis were investigated. Results: The inhibition of the monoxide synthesis (NО) in conditions of pineal gland (PG) hyperfunction violated the structures of chronorhythms acid-regulating function of the kidneys. The decrease in urine pH at daytime intervals was due to a decrease in the level of hydrogen ion excretion during this period of the day. The introduction of the NО blocker against the background of the PG hyperfunction violated the structure of the acid esterification chronorhythms that are titrated. The maximum level of this indicator was recorded at 20.00 a.m. a day. The blockade of the synthesis NО on the background of the PG hyperfunction significantly reduced the level of excretion of ammonia. Conclusions: The maximum level of excretion was 12.00 a.m., bathyphase - at 24.00 a.m. The average daily level was 1.5 mcmol/100 mcl GF and was lower relative to the control animals and animals that were in the conditions of PG hyperfunction

Цифрові технології впровадження гейміфікації в систему освіти в контекст розвитку індустрії 4.0

The main purpose of the article is to model the stages of using digital technologies for introducing gamification into the education system. In recent years, gamification has been constantly on the list of trends in Industry 4.0. It is being researched by specialists in academic and corporate training, as well as by individual educational institutions. Therefore, we believe that we should take a closer look at this technology. The methodology implies the use of information-graphic modelling methods. Based on the results of the analysis, a multi-stage model of the use of digital technologies for the introduction of the gamification system into the educational process for a specific socio-economic system was formed. The study has limitations and they relate to the use of one educational institution and do not take into account all the digital technologies that can be applied in accordance with the research topic. Further research requires the question of analyzing the complexity of the gamification implementation system in modern conditions and determining what negative consequences it can bring to the socio-economic system.Основною метою статті є моделювання етапів використання цифрових технологій для впровадження гейміфікації в систему освіти. В останні роки гейміфікація постійно була в списку трендів Індустрії 4.0. Її досліджують фахівці з академічного та корпоративного навчання, а також окремі навчальні заклади. Тому ми вважаємо, що варто уважніше придивитися до цієї технології. Методологія передбачає використання методів інформаційно-графічного моделювання. За результатами аналізу сформовано багатоетапну модель використання цифрових технологій для впровадження системи гейміфікації в освітній процес для конкретної соціально-економічної системи. Дослідження має обмеження, які стосуються використання одного навчального закладу та не враховують усі цифрові технології, які можна застосувати відповідно до теми дослідження. Подальшого дослідження потребує питання аналізу складності системи впровадження гейміфікації в сучасних умовах та визначення того, які негативні наслідки вона може мати для соціально-економічної системи

Influence of plasmapheresis on anti-ovarian antibodies level before in vitro fertilization in women with infertility

Introduction. The study of anti-ovarian autoantibodies in patients with ovarian insufficiency against the background of normal levels of gonadotropins, prolactin and androgens shows that the incidence of autoimmune oophoritis among such women varies from 19.2% to 31.5%. The objective of the study was to study the anti-ovarian antibodies level in infertile women at the preparatory stage for in vitro fertilization. Materials and methods. We examined 30 women, who were divided into the following groups: control group – 10 reproductively healthy women, who had a birth in the history (from 1 to 3); study group – 20 women with infertility of tube origin, who were included in the in vitro fertilization program. The study was performed between 2015-2017 in the Bukovinian State Medical University and Centre of Reproductive Medicine, Ukraine. The women signed the informed consent. Results. The anti-ovarian antibodies level in infertile women was found out to be 1.7 times less than in the control group. Reduction of the level of anti-ovarian antibodies in patients from the study group was marked by the obstetric and gynecological history. Conclusions. Anti-ovarian antibodies are present in both reproductively healthy women and in patients with infertility. The level of anti-ovarian antibodies can be both increased and reduced, depending on the pathological process that caused infertility. In both cases, this fact can testify the infertility. After plasmapheresis, the increased level of anti-ovarian antibodies sharply decreases

Using a Neural Network Approach to Predict Deposits on the Surfaces of Heat Exchange Equipment

This work proposes a neural network (NN) approach for predicting the following values: the heat transfer coefficient at the point of interest in the operational period of plate heat exchangers (PHEs), and the time-point to reach the lower allowable limit of the heat transfer coefficient. In this approach, neural network models replace complex mathematical modelling that used systems of differential equations and matrices of heuristic coefficients to calculate the flow rate of deposits on PHE plates, which required the involvement of serious computing resources. Training a feed-forward neural network (FFNN) on a small dataset simulated in the vicinity of reference points obtained by industrial measurements showed the proper coefficient of determination R2 = 0.99 (accuracy) of the short-term prediction forecasts and for operational evaluation of the heat transfer coefficient due to the static type of NN

NEW METHOD OF TREATMENT OF PYOINFLAMMATORY SOFT TISSUE COMPLICATIONS IN PATIENTS WITH DIABETES MELLITUS

Diabetes mellitus (DM) is a chronic, progressive disease characterized by hyperglycemia induced by impaired insulin secretion, action or both. Regardless of the type of diabetes, it puts patient at high risk of tissue, organ and vessel damage. Unfortunately the mechanisms of these damages are still not clea

Using a Neural Network Approach to Predict Deposits on the Surfaces of Heat Exchange Equipment

This work proposes a neural network (NN) approach for predicting the following values: the heat transfer coefficient at the point of interest in the operational period of plate heat exchangers (PHEs), and the time-point to reach the lower allowable limit of the heat transfer coefficient. In this approach, neural network models replace complex mathematical modelling that used systems of differential equations and matrices of heuristic coefficients to calculate the flow rate of deposits on PHE plates, which required the involvement of serious computing resources. Training a feed-forward neural network (FFNN) on a small dataset simulated in the vicinity of reference points obtained by industrial measurements showed the proper coefficient of determination R2 = 0.99 (accuracy) of the short-term prediction forecasts and for operational evaluation of the heat transfer coefficient due to the static type of NN

Social Inequality as Global Challenge

Доступ до книги на сайті видавництва (copyright) https://www.riverpublishers.com/book_details.php?book_id=922У цій книзі обговорюються чинники нерівності, закладеної в наші соціальні, економічні та політичні системи. Соціальна нерівність особливо проявляється в секторах послуг у відмінності в доступі до охорони здоров’я, освіти, соціального захисту, системи житла, догляду за дітьми, догляду за літніми тощо. соціальним статусом певної групи, мовою, релігією, звичаями та нормами є ще одна поширена проблема. Ця книга намагається представити точну картину цих проблем на прикладах з різних країн. Здебільшого, коли ми говоримо про нерівність, акцент робиться на економічній нерівності; однак зберігається значна нерівність, особливо дискримінація за статтю, віком, походженням, етнічною приналежністю, інвалідністю, сексуальною орієнтацією, класом та релігією. Щоб покласти край цій ситуації, необхідно провести соціальні, економічні та політичні реформи. Поки маргіналізовані групи не отримають повноваження, проблему нерівності неможливо вирішити чи навіть мінімізувати. На основі різних тематичних досліджень ця книга заохочує нас переосмислити розвиток суспільства через призму зростаючої нерівності та диспропорції. У книзі представлені нові ідеї для оцінки прогресу соціального розвитку. Книга висвітлює сучасні проблеми соціальної нерівності. У сукупності ця збірка відредагованих статей дає комплексне розуміння питання «чому суспільство нерівне»? Ця книга націлена на тих зацікавлених сторін, які хочуть змінити та побудувати нерозділене, соціально інклюзивне суспільство або внести свій внесок у них, а також для тих, хто хоче зробити свій внесок у розширення прав і можливостей суспільства у ХХІ столітті.В этой книге обсуждаются факторы, лежащие в основе неравенства, присущего нашим социальным, экономическим и политическим системам. Социальное неравенство особенно заметно в секторах услуг - в различиях в доступе к здравоохранению, образованию, социальной защите, жилищным системам, уходу за детьми, уходу за престарелыми и т. д. Другой широко распространенной проблемой является социальный статус конкретных групп, их язык, религия, обычаи и нормы. В этой книге делается попытка представить точную картину этих проблем на примерах из разных стран. На основе различных тематических исследований эта книга побуждает нас переосмыслить социальное развитие через призму растущего неравенства и неравенства. В книге представлены новые идеи для оценки прогресса в социальном развитии. В книге освещаются современные проблемы социального неравенства. В совокупности этот сборник отредактированных статей дает комплексное понимание вопроса «почему общество неравно»? Эта книга адресована тем заинтересованным сторонам, которые хотят внести свой вклад в изменения и построить неразделенное, социально инклюзивное общество, а также тем, кто хочет внести свой вклад в расширение прав и возможностей общества в XXI веке.This book discusses the factors behind the inequalities embedded within our social, economic and political systems. Social inequalities are especially seen in the service sectors â  in the differences of access to healthcare, education, social protection, housing systems, childcare, elderly care etc. Cultural inequality, which segregates people from the mainstream based on recognition problems with a specific groups' social status, language, religion, customs and norms, is another widespread issue. This book tries to present an accurate picture of these issues with cases studies from various countries. Mostly, when we talk about inequality, the focus is on economic inequality; however, much inequality persists, especially discrimination due to gender, age, origin, ethnicity, disability, sexual orientation, class, and religion. To end this situation there is a need for social, economic, and political reform. Until or unless the marginalized groups are empowered, the inequality issue cannot be solved or even minimized. On the basis of various case studies, this book encourages us to rethink societal development through the lens of growing inequalities and disparities. The book presents new insights for evaluating the progress on social development. The book highlights the current challenges of social inequality. In combination this collection of edited papers gives an integrated understanding of the question of “why is society unequal”? This book is aimed at those stakeholders, who want to make or contribute to change and build an undivided, socially inclusive society, and to those who want to contribute to empowering society in the Twenty-First century

EVALUATION OF THE USE OF OZONE THERAPY IN TREATMENT OF INFLAMMATORY PROCESSES IN DIABETES MELLITUS IN AN EXPERIMENT

Despite some advances in the treatment of Diabetic patients with severe localized wound infection, surgical treatment results can not be considered satisfactory. Resulting experience data in the medical practice on physical factors application for purpose of influence reparative processes stimulation associated with targeted pharmacotherapy, confirm the correctness of the search attempts. Ozonotherapy have been widely used for this purpose in recent years