Orphan SelD proteins and selenium-dependent molybdenum hydroxylases

Bacterial and Archaeal cells use selenium structurally in selenouridine-modified tRNAs, in proteins translated with selenocysteine, and in the selenium-dependent molybdenum hydroxylases (SDMH). The first two uses both require the selenophosphate synthetase gene, selD. Examining over 500 complete prokaryotic genomes finds selD in exactly two species lacking both the selenocysteine and selenouridine systems, Enterococcus faecalis and Haloarcula marismortui. Surrounding these orphan selD genes, forming bidirectional best hits between species, and detectable by Partial Phylogenetic Profiling vs. selD, are several candidate molybdenum hydroxylase subunits and accessory proteins. We propose that certain accessory proteins, and orphan selD itself, are markers through which new selenium-dependent molybdenum hydroxylases can be found

Can Social Networking Be Used to Promote Engagement in Child Maltreatment Prevention Programs? Two Pilot Studies

Introduction: Child maltreatment is one of the United States’ most significant public health problems.In efforts to prevent maltreatment experts recommend use of Behavioral Parent Training Programs(BPTs), which focus on teaching skills that will replace and prevent maltreating behavior. eScholarship provides open access, scholarly publishing services to the University of California and delivers a dynamic research platform to scholars worldwide. While there isresearch to support the effectiveness of BPTs in maltreatment prevention, the reach of such programsis still limited by several barriers, including poor retention of families in services. Recently, newtechnologies have emerged that offer innovative opportunities to improve family engagement. Thesetechnologies include smartphones and social networking; however, very little is known about thepotential of these to aid in maltreatment prevention. The primary goal of this study was to conduct 2pilot exploratory projects. Methods: The first project administered a survey to parents and providers to gather data about at-risk parents’ use of smartphones and online social networking technologies. The second project tested asocial networking-enhanced brief parenting program with 3 intervention participants and evaluatedparental responses. Results: Seventy-five percent of parents surveyed reported owning a computer that worked. Eightyninepercent of parents reported that they had reliable Internet access at home, and 67% said theyused the Internet daily. Three parents participated in the intervention with all reporting improvement in parent-child interaction skills and a positive experience participating in the social networking-enhanced SafeCare components. Conclusion: In general, findings suggest that smartphones, social networking, and Facebook, in particular, are now being used by individuals who show risk factors forma treatment. Further, themajorityof parents surveyed in this study said that they like Facebook, and all parents surveyed said that they useFacebook and have a Facebook account. As well, all saw it as a potentially beneficial supplement forfuture parents enrolling in parenting programs

Marginal Cost Analysis of Two Train-the-Trainer Models for Implementing SafeCare

[West J Emerg Med. 2014;15(5):623–626.

Technology-Based Innovations in Child Maltreatment Prevention Programs: Examples from SafeCare®

Each year, hundreds of thousands of children in the U.S. are victims of child maltreatment. Experts recommend behavioral, skill-based parent training programs as a strategy for the prevention of child abuse and neglect. These programs can be enhanced using innovative technology strategies. This paper presents a brief history of the use of technology in SafeCare®, a home visiting program shown to prevent child neglect and physical abuse, and highlights current work that takes a technology-based hybrid approach to SafeCare delivery. With this unique approach, the provider brings a tablet computer to each session, and the parent interacts with the software to receive psychoeducation and modeling of target skills. The provider and parent then work together to practice the targeted skills until mastery is achieved. Initial findings from ongoing research of both of these strategies indicate that they show potential for improving engagement and use of positive parenting skills for parents and ease of implementation for providers. Future directions for technology enhancements in SafeCare are also presented

Holocene climate and environmental change in north-eastern Kamchatka (Russian Far East), inferred from a multi-proxy study of lake sediments

The study was supported by the Swedish Research Council through grants 621-2004-5224 and 621-2005-4444 to K.D. Bennett. A. Self and N. Solovieva acknowledge S. Brooks and V. Jones and were supported by NERC grant NE/H008160/1.A sediment record from a small lake in the north-eastern part of the Kamchatka Peninsula has been investigated in a multi-proxy study to gain knowledge of Holocene climatic and environmental change. Pollen, diatoms, chironomids and selected geochemical parameters were analysed and the sediment record was dated with radiocarbon. The study shows Holocene changes in the terrestrial vegetation as well as responses of the lake ecosystem to catchment maturity and multiple stressors, such as climate change and volcanic eruptions. Climate change is the major driving force resulting in the recorded environmental changes in the lake, although recurrent tephra deposition events also contributed. The sediment record has an age at the base of about 10,000 cal yrs BP, and during the first 400 years the climate was cold and the lake exhibited extensive ice-cover during winter and relatively low primary production. Soils in the catchment were poor with shrub alder and birches dominating the vegetation surrounding the lake. At about 9600–8900 cal yrs BP the climate was cold and moist, and strong seasonal wind stress resulted in reduced ice-cover and increased primary production. After ca. 8900 cal yrs BP the forest density increased around the lake, runoff decreased in a generally drier climate resulting in decreased primary production in the lake until ca. 7000 cal yrs BP. This generally dry climate was interrupted by a brief climatic perturbation, possibly attributed to the 8.2 ka event, indicating increasingly windy conditions with thick snow cover, reduced ice-cover and slightly elevated primary production in the lake. The diatom record shows maximum thermal stratification at ca. 6300–5800 cal yrs BP and indicates together with the geochemical proxies a dry and slightly warmer climate resulting in a high productive lake. The most remarkably change in the catchment vegetation occurred at ca. 4200 cal yrs BP in the form of a conspicuous increase in Siberian dwarf pine (Pinus pumila), indicating a shift to a cooler climate with a thicker and more long-lasting snow cover. This vegetational change was accompanied by marked shifts in the diatom and chironomid stratigraphies, which are also indicative of colder climate and more extensive ice-cover.Publisher PDFPeer reviewe

Dynamic Adaptation Process to Implement an Evidence-based Child Maltreatment Intervention

Background: Adaptations are often made to evidence-based practices (EBPs) by systems, organizations, and/or service providers in the implementation process. The degree to which core elements of an EBP can be maintained while allowing for local adaptation is unclear. In addition, adaptations may also be needed at the system, policy, or organizational levels to facilitate EBP implementation and sustainment. This paper describes a study of the feasibility and acceptability of an implementation approach, the Dynamic Adaptation Process (DAP), designed to allow for EBP adaptation and system and organizational adaptations in a planned and considered, rather than ad hoc, way. The DAP involves identifying core elements and adaptable characteristics of an EBP, then supporting implementation with specific training on allowable adaptations to the model, fidelity monitoring and support, and identifying the need for and solutions to system and organizational adaptations. In addition, this study addresses a secondary concern, that of improving EBP model fidelity assessment and feedback in real-world settings. Methods: This project examines the feasibility, acceptability, and utility of the DAP; tests the degree to which fidelity can be maintained using the DAP compared to implementation as usual (IAU); and examines the feasibility of using automated phone or internet-enabled, computer-based technology to assess intervention fidelity and client satisfaction. The study design incorporates mixed methods in order to describe processes and factors associated with variations in both how the DAP itself is implemented and how the DAP impacts fidelity, drift, and adaptation. The DAP model is to be examined by assigning six regions in California (USA) to either the DAP (n = 3) or IAU (n = 3) to implement an EBP to prevent child neglect. Discussion: The DAP represents a data-informed, collaborative, multiple stakeholder approach to maintain intervention fidelity during the implementation of EBPs in the field by providing support for intervention, system, and organizational adaptation and intervention fidelity to meet local needs. This study is designed to address the real-world implications of EBP implementation in public sector service systems and is relevant for national, state, and local service systems and organizations

The Student Movement Volume 105 Issue 15: SASA\u27s Saris Shine at Cultural Celebration

NEWS SASA Hosts Once Upon a Time in Bollywood , Caralynn Chan Vaccinated: Andrews Students Receive Fist Dose of COVID-19 Vaccine, Taylor Uphus PULSE AAPI Issues on Campus: A Dialogue, Jessica Rim Student Features: The Story Behind the Car, Interviews by Wambui Karanja Summer Plans: STEM Majors, Interviews by Masy Domecillo HUMANS A Quarter Century of Research, Interviewed by Alyssa Henriquez An Interview with Taylor Biek: Next Year\u27s AUSA Social VP, Interviewed by Abigail Lee Makarios Easter Passion Play, Interviewed by Ben Lee ARTS & ENTERTAINMENT April Current Favorite Songs, Hannah Cruse Celebrating National Poetry Month, Alannah Tjhatra Creative Spotlight: Karen Garcia, Interviewed by Megan Napod Signal Boost: Rookie Historian Goo Hae-ryung, Hannah Cruse IDEAS A Birthday Boy\u27s Reflections: What I\u27m Learning Now, Adoniah Simon Biden\u27s Job Plan: The Latest Example of Government Investment in Our Future, Lyle Goulbourne THE LAST WORD My (Last) Last Word, Daniel Selfhttps://digitalcommons.andrews.edu/sm-105/1019/thumbnail.jp

The Student Movement Volume 105 Issue 7: Putting the Finishing Touches on Fall Semester

NEWS Andrews Releases Spring 2021 Opening Plan, Amanda Cho Creating Visions for the Future, Joelle Kim Semester Reflections: Living During a Global Pandemic, Taylor Uphus PULSE The Best Drive-Through Meals, Masy Domecillo Reviewing Leaving the Shadowland of Stress, Depression, and Anxiety , Jessica Rim Study Tips: Re-Examining Routine, Wambui Karanja HUMANS Christmas vs. Thanksgiving, Interviewed by Abigail Lee Interview with Dongchan Kim, AUSA Executive Vice President, Interviewd by Ben Lee Studying Abroad in Argentina: An Interview with Lisiane Umuhire, Interviewed by TJ Hunter ARTS & ENTERTAINMENT Creative Spotlight: Ivan Rachath, Interviewed by Megan Napod Elementary, Hannah Cruse It\u27s Beginning to Sound A Lot Like Christmas!, Megan Napod IDEAS The Good, Kyara Samuels The Power of Resource, Evin N. Musgrove LAST WORD Fallen Titans: Remembering Alex Trebek and Rabbi Jonathan Sacks, Daniel Selfhttps://digitalcommons.andrews.edu/sm-105/1008/thumbnail.jp

Toward Estimating Noise–Power–Distance Curves for Propeller-Powered Zero-Emission Hydrogen Aircraft

As part of the UK Research and Innovation project New Aviation, Propulsion, Knowledge and Innovation Network (NAPKIN), a high-level framework was developed for the assessment of the noise impact of the proposed regional-sized hydrogen-powered aircraft. This study consists of the methodology used to generate the industry-standard noise–power–distance (NPD) curves from individual component noise analysis, specifically propeller tonal noise. The model is based on an asymptotic analysis of a frequency domain propeller tonal noise model combined with a linear approximation, taking advantage of the logarithmic nature of noise. An error analysis on the linear approximation assumption proves that the relative error between predicted and actual values of the noise remains below 10% for appropriately chosen baseline points. Verification of the framework was achieved through a bench-marking procedure that compared predictions of departure NPD curves for current technology regional aircraft against published ones over a range of operational power settings. Finally, departure and approach NPD predictions for three of the NAPKIN hydrogen concept aircraft are presented. Concepts featuring a larger, slower-rotating propeller with an increased number of blades relative to the reference aircraft showed benefits over the reference aircraft, despite, in some cases, increases in maximum takeoff weight

The Student Movement Volume 105 Issue 6: AU Infused with New Cultural Perspectives

NEWS Andrews University Wind Symphony Performs Songs of the Sea Concert, Jenae Rogers Dr. Marilyn McEntyre Speaks at John O. Walker Lecture, Taylor Uphus Students Worship Together at Infusion Vespers, Caralynn Chan PULSE Interest and Apathy Towards Politics, Wambui Karanja Memories of Chuseok: Celebrating Community, Jessica Rim Pumpkin Spice: Deconstructed, Masy Domecillo HUMANS Explaining the Letter: Talking with Kelli Coffen, Interviewed by Abigail Lee Holly Sharp, AFIA Cultural VP, on Filipino American History Month, Interviewed by Terika Williams Thoughts on the Last Presidential Debate, Interviewed by Alyssa Henriquez ARTS & ENTERTAINMENT Another Fall Playlist!, Created by Evin N. Musgrove Artist Spotlight: Courtney Saunders, Interviewed by Pearl Parker Unorthodox, Hannah Cruse IDEAS Get Your Flu Shot! Now More Than Ever, Sung Been Han Just This Once , Evin N. Musgrove LAST WORD Apoliticism in Election Season, Daniel Selfhttps://digitalcommons.andrews.edu/sm-105/1006/thumbnail.jp