The efficacy of 8% Arginine-CaCO3 applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study

Objectives: Periodontal therapy is one of the etiological factors of dentine hypersensitivity (DH). This study aimed to evaluate the efficacy of %8Arginine-CaCO 3 on DH that affects patients after periodontal treatment. Study design: Seventy-one teeth from the volunteers (n=36) with history of DH caused by periodontal therapy were included in this study, and randomly divided into two groups: group-1, who received 8%Arginine-CaCO 3 and group-2, who received 1.23%NaF-gel. The clinical indices were recorded at first visit.DH was evaluated by using tactile, air-blast, and thermal stimuli. The subject's response was recorded at baseline, immediately (Day-0) and one month after the application. Results and conclusions: The results were statistically analyzed, and it was found that 8% Arginine-CaCO 3 treat - ment was more effective than 1.23% NaF-gel at time intervals. Sensitivity score differences between the groups were statistically significant at Day-28. The 8% Arginine-CaCO 3 group exhibited statistically significant reduc - tion in DH on three stimuli at baseline to Day-28. It was concluded that 8% Arginine-CaCO 3 is more effective than 1.23% NaF-gel in reduction of patients' pain

Histologic and Histomorphometric Assessment of Eggshell-Derived Bone Graft Substitutes on Bone Healing in Rats

Objective: The objective of this study was to histologically and histomorphometrically evaluate the efficacy of the new formulations of eggshell-derived calcium carbonate in rats. Study Design: The study was conducted on 30 adult male rats. Four standardized and circular intra-bony defects were created in the both maxilla and mandibula of each animal. Three different graft materials were prepared as follows: 1) Material A: Eggshell-derived calcium carbonate combined with carrageenan gel, 2) Material B: Eggshellderived calcium carbonate combined with xanthan gum gel, and 3) Material C: Eggshell-derived calcium carbonate powder. The right mandibular defect sites were grafted with Material A in all animals, and defects on the left were grafted with Material B. Defects on the right side of maxilla were received Material C in all animals, and all left maxillary defects were remained untreated as controls. The animals were sacrificed either postoperatively on the 15th day, postoperatively on the 30th day or postoperatively on the 45th day. Histomorphometric measurements were made of the areas of newly formed bone, necrotic bone, fibrous tissue and residual graft material. Results: Material A exhibited the highest level of osteoid formation followed by Material B and Material C on the 45th day. In terms of osteoid formation, statistically significant differences were observed between graft materials and controls at 45th day compared to 15th and 30th day (p<0.05). Conclusions: Eggshell-derived graft substitutes in both gel and powder forms are biocompatible materials which may have the potential to enhance the new bone formation

Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome

BACKGROUND & AIMS: Interferon is the only effective treatment for chronic hepatitis D virus (HDV) infection. No rules have been set for stopping treatment based on viral kinetics. We analyzed data from an international study of hepatitis D treatment to identify factors associated with outcomes of pegylated interferon treatment, with and without adefovir

Two Percent Chitosan Mouthwash: A Microbiological And Clinical Comparative Study

Background/purpose: The aim of this study was to evaluate the microbiological and clinical effects of a chitosan (CH) mouth rinse on plaque inhibition. Materials and methods: Thirty-six healthy participants were recruited. The following clinical data were recorded: a plaque index (PI), gingival index (GI), Quickley-Hein plaque index (QPI), and probing depth (PD). Volunteers were given oral hygiene (OH) instruction and trained on scaling and professional tooth cleaning (PTC). After the final PTC, volunteers were randomly allocated into three groups. Group A rinsed with 2% CH, group B rinsed with 0.2% chlorhexidine digluconate (CHX), and group C rinsed with 2% CH 0.2% CHX. Plaque samples were collected and assayed for Streptococcus mutans, Candida albicans, and enterococci. Results: After a non-brushing period, the full-mouth PI and QPI values between the CH and CHX + CH groups differed significantly. A higher PI score at sampling sites was seen in the CH group, but no significant differences were observed between groups. The S. mutans and C. albicans levels were statistically significant in each group on Days 0 and 4. Differences of C. albicans levels between groups were found to be significant; however, no statistical differences were obtained for S. mutans or enterococci levels among the groups at the various time intervals. Conclusion: We conclude that further investigations are needed to evaluate the potential value of CH as an effective antiplaque mouth rinse. Copyright (C) 2012, Association for Dental Sciences of the Republic of China. Published by Elsevier Taiwan LLC. All rights reserved.WoSScopu

Kardiyovasküler İşlemlerde Görüntüleme

Doğum sırasındaki fizyolojik değişimlerle kapanması öngörülen foramen ovale erişkin populasyonun yaklaşık %75’inde tamamen kapanmış olarak izlenirken, %25’inde ise kapanmaz ve patent foramen ovale (PFO) olarak varlığını sürdürür.1 PFO, serebrovasküler olay dahil birçok patoloji (auralı migren, dalgıçlarda dekompresyon hastalığı vs.) ile ilişkilendirilmiştir. İskemik inmelerin %25’inde standart tanısal değerlendirmeye rağmen bir neden bulunamaz ve bu grup kriptojenik inme olarak adlandırılır. PFO ve kriptojenik inme arasındaki patofizyolojik ilişki paradoksal embolizm, PFO içerisinde meydana gelen trombüs, sol atriyal disfonksiyon ve atriyal aritmiler gibi nedenlere bağlı olabilir. Epidemiyolik veriler ve klinik gözlemsel çalışmalar, PFO kapatılmasıyla inme rekürrenslerinin azaldığını gösteren randomize kontrollü çalışmalar tarafından kuvvetle desteklenmektedir.2 PFO’nun tanısında ve perkütan tedavisinde çoklu görüntüleme yöntemleri önem arz etmektedir