Prevention of bone mineral changes induced by bed rest: Modification by static compression simulating weight bearing, combined supplementation of oral calcium and phosphate, calcitonin injections, oscillating compression, the oral diophosphonatedisodium etidronate, and lower body negative pressure

The phenomenon of calcium loss during bed rest was found to be analogous to the loss of bone material which occurs in the hypogravic environment of space flight. Ways of preventing this occurrence are investigated. A group of healthy adult males underwent 24-30 weeks of continuous bed rest. Some of them were given an exercise program designed to resemble normal ambulatory activity; another subgroup was fed supplemental potassium phosphate. The results from a 12-week period of treatment were compared with those untreated bed rest periods. The potassium phosphate supplements prevented the hypercalciuria of bed rest, but fecal calcium tended to increase. The exercise program did not diminish the negative calcium balance. Neither treatment affected the heavy loss of mineral from the calcaneus. Several additional studies are developed to examine the problem further

Steady state free radical budgets and ozone photochemistry during TOPSE

A steady state model, constrained by a number of measured quantities, was used to derive peroxy radical levels for the conditions of the Tropospheric Ozone Production about the Spring Equinox (TOPSE) campaign. The analysis is made using data collected aboard the NCAR/NSF C-130 aircraft from February through May 2000 at latitudes from 40° to 85°N, and at altitudes from the surface to 7.6 km. HO2 + RO2 radical concentrations were measured during the experiment, which are compared with model results over the domain of the study showing good agreement on the average. Average measurement/model ratios are 1.04 (σ = 0.73) and 0.96 (σ = 0.52) for the MLB and HLB, respectively. Budgets of total peroxy radical levels as well as of individual free radical members were constructed, which reveal interesting differences compared to studies at lower latitudes. The midlatitude part of the study region is a significant net source of ozone, while the high latitudes constitute a small net sink leading to the hypothesis that transport from the middle latitudes can explain the observed increase in ozone in the high latitudes. Radical reservoir species concentrations are modeled and compared with the observations. For most conditions, the model does a good job of reproducing the formaldehyde observations, but the peroxide observations are significantly less than steady state for this study. Photostationary state (PSS) derived total peroxy radical levels and NO/NO2ratios are compared with the measurements and the model; PSS-derived results are higher than observations or the steady state model at low NO concentrations

Special Libraries, May-June 1932

Volume 23, Issue 5https://scholarworks.sjsu.edu/sla_sl_1932/1004/thumbnail.jp

Spatio-temporal variability and trends of precipitation and extreme rainfall events in Ethiopia in 1980–2010

This article summarizes the results from an analysis conducted to investigate the spatio-temporal variability and trends in the rainfall over Ethiopia over a period of 31 years from 1980 to 2010. The data is mostly observed station data supplemented by bias-corrected AgMERRA climate data. Changes in annual and Belg (March–May) and Kiremt (June to September) season rainfalls and rainy days have been analysed over the entire Ethiopia. Rainfall is characterized by high temporal variability with coefficient of variation (CV, %) varying from 9 to 30% in the annual, 9 to 69% during the Kiremt season and 15–55% during the Belg season rainfall amounts. Rainfall variability increased disproportionately as the amount of rainfall declined from 700 to 100 mm or less. No significant trend was observed in the annual rainfall amounts over the country, but increasing and decreasing trends were observed in the seasonal rainfall amounts in some areas. A declining trend is also observed in the number of rainy days especially in Oromia, Benishangul-Gumuz and Gambella regions. Trends in seasonal rainfall indicated a general decline in the Belg season and an increase in the Kiremt season rainfall amounts. The increase in rainfall during the main Kiremt season along with the decrease in the number of rainy days leads to an increase in extreme rainfall events over Ethiopia. The trends in the 95th-percentile rainfall events illustrate that the annual extreme rainfall events are increasing over the eastern and south-western parts of Ethiopia covering Oromia and Benishangul-Gumuz regions. During the Belg season, extreme rainfall events are mostly observed over central Ethiopia extending towards the southern part of the country while during the Kiremt season, they are observed over parts of Oromia, (covering Borena, Guji, Bali, west Harerge and east Harerge), Somali, Gambella, southern Tigray and Afar regions. Changes in the intensity of extreme rainfall events are mostly observed over south-eastern parts of Ethiopia extending to the south-west covering Somali and Oromia regions. Similar trends are also observed in the greatest 3-, 5- and 10-day rainfall amounts. Changes in the consecutive dry and wet days showed that consecutive wet days during Belg and Kiremt seasons decreased significantly in many areas in Ethiopia while consecutive dry days increased. The consistency in the trends over large spatial areas confirms the robustness of the trends and serves as a basis for understanding the projected changes in the climate. These results were discussed in relation to their significance to agriculture

Evaluation of the health-related quality of life of children in Schistosoma haematobium-endemic communities in Kenya: a cross-sectional study.

BACKGROUND: Schistosomiasis remains a global public health challenge, with 93% of the ~237 million infections occurring in sub-Saharan Africa. Though rarely fatal, its recurring nature makes it a lifetime disorder with significant chronic health burdens. Much of its negative health impact is due to non-specific conditions such as anemia, undernutrition, pain, exercise intolerance, poor school performance, and decreased work capacity. This makes it difficult to estimate the disease burden specific to schistosomiasis using the standard DALY metric. METHODOLOGY/PRINCIPAL FINDINGS: In our study, we used Pediatric Quality of Life Inventory (PedsQL), a modular instrument available for ages 2-18 years, to assess health-related quality of life (HrQoL) among children living in a Schistosoma haematobium-endemic area in coastal Kenya. The PedsQL questionnaires were administered by interview to children aged 5-18 years (and their parents) in five villages spread across three districts. HrQoL (total score) was significantly lower in villages with high prevalence of S. haematobium (-4.0%, p<0.001) and among the lower socioeconomic quartiles (-2.0%, p<0.05). A greater effect was seen in the psychosocial scales as compared to the physical function scale. In moderate prevalence villages, detection of any parasite eggs in the urine was associated with a significant 2.1% (p<0.05) reduction in total score. The PedsQL reliabilities were generally high (Cronbach alphas ≥0.70), floor effects were acceptable, and identification of children from low socioeconomic standing was valid. CONCLUSIONS/SIGNIFICANCE: We conclude that exposure to urogenital schistosomiasis is associated with a 2-4% reduction in HrQoL. Further research is warranted to determine the reproducibility and responsiveness properties of QoL testing in relation to schistosomiasis. We anticipate that a case definition based on more sensitive parasitological diagnosis among younger children will better define the immediate and long-term HrQoL impact of Schistosoma infection

Flexible Lifestyles for Youth (FL3X) behavioural intervention for at-risk adolescents with Type 1 diabetes: a randomized pilot and feasibility trial

To determine the potential effect sizes for the Flexible Lifestyle for Youth (FL3X) behavioural intervention to improve glycaemic control (HbA1c) and quality of life for at-risk adolescents with Type 1 diabetes

Steady state free radical budgets and ozone photochemistry during TOPSE

A steady state model, constrained by a number of measured quantities, was used to derive peroxy radical levels for the conditions of the Tropospheric Ozone Production about the Spring Equinox (TOPSE) campaign. The analysis is made using data collected aboard the NCAR/NSF C‐130 aircraft from February through May 2000 at latitudes from 40° to 85°N, and at altitudes from the surface to 7.6 km. HO2 + RO2 radical concentrations were measured during the experiment, which are compared with model results over the domain of the study showing good agreement on the average. Average measurement/model ratios are 1.04 (σ = 0.73) and 0.96 (σ = 0.52) for the MLB and HLB, respectively. Budgets of total peroxy radical levels as well as of individual free radical members were constructed, which reveal interesting differences compared to studies at lower latitudes. The midlatitude part of the study region is a significant net source of ozone, while the high latitudes constitute a small net sink leading to the hypothesis that transport from the middle latitudes can explain the observed increase in ozone in the high latitudes. Radical reservoir species concentrations are modeled and compared with the observations. For most conditions, the model does a good job of reproducing the formaldehyde observations, but the peroxide observations are significantly less than steady state for this study. Photostationary state (PSS) derived total peroxy radical levels and NO/NO2 ratios are compared with the measurements and the model; PSS‐derived results are higher than observations or the steady state model at low NO concentrations

Chemical composition of Asian continental outflow over the western Pacific: Results from Transport and Chemical Evolution over the Pacific (TRACE‐P)

We characterize the chemical composition of Asian continental outflow observed during the NASA Transport and Chemical Evolution over the Pacific (TRACE‐P) mission during February–April 2001 in the western Pacific using data collected on the NASA DC‐8 aircraft. A significant anthropogenic impact was present in the free troposphere and as far east as 150°E longitude reflecting rapid uplift and transport of continental emissions. Five‐day backward trajectories were utilized to identify five principal Asian source regions of outflow: central, coastal, north‐northwest (NNW), southeast (SE), and west‐southwest (WSW). The maximum mixing ratios for several species, such as CO, C2Cl4, CH3Cl, and hydrocarbons, were more than a factor of 2 larger in the boundary layer of the central and coastal regions due to industrial activity in East Asia. CO was well correlated with C2H2, C2H6, C2Cl4, and CH3Cl at low altitudes in these two regions (r2 ∼ 0.77–0.97). The NNW, WSW, and SE regions were impacted by anthropogenic sources above the boundary layer presumably due to the longer transport distances of air masses to the western Pacific. Frontal and convective lifting of continental emissions was most likely responsible for the high altitude outflow in these three regions. Photochemical processing was influential in each source region resulting in enhanced mixing ratios of O3, PAN, HNO3, H2O2, and CH3OOH. The air masses encountered in all five regions were composed of a complex mixture of photochemically aged air with more recent emissions mixed into the outflow as indicated by enhanced hydrocarbon ratios (C2H2/CO ≥ 3 and C3H8/C2H6 ≥ 0.2). Combustion, industrial activities, and the burning of biofuels and biomass all contributed to the chemical composition of air masses from each source region as demonstrated by the use of C2H2, C2Cl4, and CH3Cl as atmospheric tracers. Mixing ratios of O3, CO, C2H2, C2H6, SO2, and C2Cl4 were compared for the TRACE‐P and PEM‐West B missions. In the more northern regions, O3, CO, and SO2 were higher at low altitudes during TRACE‐P. In general, mixing ratios were fairly similar between the two missions in the southern regions. A comparison between CO/CO2, CO/CH4, C2H6/C3H8, NOx/SO2, and NOy/(SO2 + nss‐SO4) ratios for the five source regions and for the 2000 Asian emissions summary showed very close agreement indicating that Asian emissions were well represented by the TRACE‐P data and the emissions inventory