146 research outputs found

    Development and research directions in ship recycling : a systematic literature review with bibliometric analysis

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    Ship recycling has gained significant importance in recent years due to the growing awareness of environmental concerns and the need for sustainable practices within the maritime industry. As vessels reach the end of their operational life, proper recycling methods are crucial to mitigate environmental impacts and promote resource conservation. With an increasing number of ships being decommissioned annually, there has been a growing interest and emphasis on developing efficient and eco-friendly ship recycling practices worldwide. This article presents a systematic literature review and bibliometric analysis of 228 studies on ship recycling indexed in Scopus. Employing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) methodology for its robustness in comprehensive literature analysis, this review uncovers key insights into prominent countries, authors, journals, collaborations, topics, and historical trends in ship recycling research, thereby extending the scope of previous reviews. Notably, major contributions from Turkey, India, Bangladesh, the USA, and China focus on environmental impact studies, reflecting urgent global sustainability concerns. The review discusses commonly adopted methodologies such as Life Cycle Assessment and Elemental Analysis, shedding light on their application in this field. Through thematic analysis across 8 categories, future research pathways are identified, highlighting crucial areas such as continuous environmental monitoring, innovative renewable energy extraction from end-of-life vessels, and the need for human factors in ship recycling. This comprehensive synthesis of existing knowledge and identification of emergent research needs and opportunities serve as a foundational resource for impactful future research and informed policymaking, particularly in aligning with global environmental and sustainability goals. Researchers, policymakers and other stakeholders in maritime safety and environmental sustainability may find the knowledge gained from this systematic literature review insightful

    Nurse participation in legal executions: An ethics round-table discussion

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    A paper was published in 2003 discussing the ethics of nurses participating in executions by inserting the intravenous line for lethal injections and providing care until death. This paper was circulated on an international email list of senior nurses and academics to engender discussion. From that discussion, several people agreed to contribute to a paper expressing their own thoughts and feelings about the ethics of nurses participating in executions in countries where capital punishment is legal. While a range of opinions were presented, these opinions fell into two main themes. The first of these included reflections on the philosophical obligations of nurses as caregivers who support those in times of great need, including condemned prisoners at the end of life. The second theme encompassed the notion that no nurse ever should participate in the active taking of life, in line with the codes of ethics of various nursing organisations. This range of opinions suggests the complexity of this issue and the need for further public discussion

    Optical gain in 1.3-μm electrically driven dilute nitride VCSOAs

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    We report the observation of room-temperature optical gain at 1.3 μm in electrically driven dilute nitride vertical cavity semiconductor optical amplifiers. The gain is calculated with respect to injected power for samples with and without a confinement aperture. At lower injected powers, a gain of almost 10 dB is observed in both samples. At injection powers over 5 nW, the gain is observed to decrease. For nearly all investigated power levels, the sample with confinement aperture gives slightly higher gain

    Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity

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    Background: Activated phosphoinositide-3-kinase d syndrome (APDS) is an inborn error of immunity (IEI) with infection susceptibility and immune dysregulation, clinically overlapping with other conditions. Management depends on disease evolution, but predictors of severe disease are lacking. Objectives: This study sought to report the extended spectrum of disease manifestations in APDS1 versus APDS2; compare these to CTLA4 deficiency, NFKB1 deficiency, and STAT3 gain of-function (GOF) disease; and identify predictors of severity in APDS. Methods: Data was collected from the ESID (European Society for Immunodeficiencies)-APDS registry and was compared with published cohorts of the other IEIs. Results: The analysis of 170 patients with APDS outlines high penetrance and early onset of APDS compared to the other IEIs. The large clinical heterogeneity even in individuals with the same PIK3CD variant E1021K illustrates how poorly the genotype predicts the disease phenotype and course. The high clinical overlap between APDS and the other investigated IEIs suggests relevant pathophysiological convergence of the affected pathways. Preferentially affected organ systems indicate specific pathophysiology: bronchiectasis is typical of APDS1; interstitial lung disease and enteropathy are more common in STAT3 GOF and CTLA4 deficiency. Endocrinopathies are most frequent in STAT3 GOF, but growth impairment is also common, particularly in APDS2. Early clinical presentation is a risk factor for severe disease in APDS. Conclusions: APDS illustrates how a single genetic variant can result in a diverse autoimmune-lymphoproliferative phenotype. Overlap with other IEIs is substantial. Some specific features distinguish APDS1 from APDS2. Early onset is a risk factor for severe disease course calling for specific treatment studies in younger patients. (J Allergy Clin Immunol 2023;152:984-96.

    Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins

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    Single-molecule Förster-resonance energy transfer (smFRET) experiments allow the study of biomolecular structure and dynamics in vitro and in vivo. We performed an international blind study involving 19 laboratories to assess the uncertainty of FRET experiments for proteins with respect to the measured FRET efficiency histograms, determination of distances, and the detection and quantification of structural dynamics. Using two protein systems with distinct conformational changes and dynamics, we obtained an uncertainty of the FRET efficiency ≤0.06, corresponding to an interdye distance precision of ≤2 Å and accuracy of ≤5 Å. We further discuss the limits for detecting fluctuations in this distance range and how to identify dye perturbations. Our work demonstrates the ability of smFRET experiments to simultaneously measure distances and avoid the averaging of conformational dynamics for realistic protein systems, highlighting its importance in the expanding toolbox of integrative structural biology

    Study of single sweep event related brain potentials in dyslexia

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    The study of event-related potentials in dyslexic children requires particular attention in the definition of the clinical and analysis protocols. The clinical protocol here described was studied for the analysis of the different functions involved in the reading process. The analysis procedure is aimed to the reduction of ocular artifact, to the extraction of single sweep responses, to the estimation of parameters for the characterization of the processes involved in the reading function. A group of normal and dyslexic children was studied, and different mechanisms were evidenced during the reading function, through the evaluation of the activation sequence of the involved cortical areas
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