Testing and evaluation of Dacron parachute elements after exposure to ethylene oxide and simulated package loading and heat cycle

Testing Dacron parachute components and assemblies by exposure to ethylene oxide sterilization, simulated package loading, and heat cycl

Radar studies of the planets

The radar measurements phase of the lunar studies involving reflectivity and topographic mapping of the visible lunar surface was ended in December 1972, but studies of the data and production of maps have continued. This work was supported by Manned Spacecraft Center, Houston. Topographic mapping of the equatorial regions of Mars has been carried out during the period of each opposition since that of 1967. The method comprised extended precise traveling time measurements to a small area centered on the subradar point. As measurements continued, planetary motions caused this point to sweep out extensive areas in both latitude and longitude permitting the development of a fairly extensive topographical map in the equatorial region. Radar observations of Mercury and Venus have also been made over the past few years. Refinements of planetary motions, reflectivity maps and determinations of rotation rates have resulted

Structural characterization and comparison of iridium, platinum and gold/palladium ultra-thin film coatings for STM of biomolecules

Scanning tunneling microscopy (STM) is capable of atomic resolution and is ideally suited for imaging surfaces with uniform work function. A biological sample on a conducting substrate in air does not meet this criteria and requires a conductive coating for stable and reproducible STM imaging. In this paper, the authors describe the STM and transmission electron microscopy (TEM) characterization of ultra-thin ion-beam sputtered films of iridium and cathode sputtered gold/palladium and platinum films on highly ordered pyrolytic graphite (HOPG) which were developed for use as biomolecule coatings. The goals were the development of metal coatings sufficiently thin and fine grained that 15--20 {angstrom} features of biological molecules could be resolved using STM, and the development of a substrate/coating system which would allow complementary TEM information to be obtained for films and biological molecules. The authors demonstrate in this paper that ion-beam sputtered iridium on highly ordered pyrolytic graphite (HOPG) has met both these goals. The ion-beam sputtered iridium produced a very fine grained (< 10 {angstrom}) continuous film at 5--6 {angstrom} thickness suitable for stable air STM imaging. In comparison, cathode sputtered platinum produced 16 {angstrom} grains with the thinnest continuous film at 15 {angstrom} thickness, and the sputtered gold/palladium produced 25 {angstrom} grains with the thinnest continuous film at 18 {angstrom} thickness

Fish Bioenergetics 4.0: An R‐Based Modeling Application

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141352/1/fsh0586.pd

A Signature of Maternal Anti-Fetal Rejection in Spontaneous Preterm Birth: Chronic Chorioamnionitis, Anti-Human Leukocyte Antigen Antibodies, and C4d

Chronic chorioamnionitis is found in more than one-third of spontaneous preterm births. Chronic chorioamnionitis and villitis of unknown etiology represent maternal anti-fetal cellular rejection. Antibody-mediated rejection is another type of transplantation rejection. We investigated whether there was evidence for antibody-mediated rejection against the fetus in spontaneous preterm birth.This cross-sectional study included women with (1) normal pregnancy and term delivery (n = 140) and (2) spontaneous preterm delivery (n = 140). We analyzed maternal and fetal sera for panel-reactive anti-HLA class I and class II antibodies, and determined C4d deposition on umbilical vein endothelium by immunohistochemistry. Maternal anti-HLA class I seropositivity in spontaneous preterm births was higher than in normal term births (48.6% vs. 32.1%, p = 0.005). Chronic chorioamnionitis was associated with a higher maternal anti-HLA class I seropositivity (p<0.01), significant in preterm and term birth. Villitis of unknown etiology was associated with increased maternal and fetal anti-HLA class I and II seropositivity (p<0.05, for each). Fetal anti-HLA seropositivity was closely related to maternal anti-HLA seropositivity in both groups (p<0.01, for each). C4d deposition on umbilical vein endothelium was more frequent in preterm labor than term labor (77.1% vs. 11.4%, p<0.001). Logistic regression analysis revealed that chronic chorioamnionitis (OR = 6.10, 95% CI 1.29–28.83), maternal anti-HLA class I seropositivity (OR = 5.90, 95% CI 1.60–21.83), and C4d deposition on umbilical vein endothelium (OR = 36.19, 95% CI 11.42–114.66) were associated with preterm labor and delivery.A major subset of spontaneous preterm births has a signature of maternal anti-fetal cellular and antibody-mediated rejections with links to fetal graft-versus-host disease and alloimmune reactions

Is Iowa making the grade?: An assessment of K-12 health education programs in public schools

There is great potential for health education, when facilitated well in public schools, to provide future leaders with the knowledge and literacy tools needed to improve health. The focus of this research was to explore the challenges faced in teaching and supporting health education in Iowa public schools. It is the intent of this study to further understand what Iowa health education teachers and district administrators perceive as barriers to successfully facilitating a robust health education program. For this study, semistructured interviews were used to further understand the lived experiences of health education teachers and curriculum directors in Iowa public schools. The interviews captured how these experiences impact student learning. They were designed to illustrate current health education and district administrative support to better understand the learning conditions in the health education classroom. The research offers many implications for health education teachers, school district administrators, policy makers, and stakeholders at all levels. The data collected from this study could assist school district administrators and health education teachers in understanding the barriers associated with facilitating a solid health education program and offer suggestions for improving public health education. The various groups could use this information to look critically at the impact of a strong health education program and to improve the level of health literacy in their students