426 research outputs found

    The management of expatriates : contemporary developments and future challenges

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    The rapid growth of international business at a time when many multinational companies (MNCs) are under increasing cost pressures has led these organisations to take a much closer look at their expatriation policies and practices. Faced with unprecedented levels of foreign competition at home and abroad, firms are beginning to recognise not only that international business is high on top management's list of priorities but that finding and nurturing the human resources required to implement an international strategy is of critical importance (Dowling et al., 1994). Much of the research on the management of expatriates currently available is drawn from research focused on North American multinationals. Adler (1997) commented that most research on international human resource management was concerned with American expatriates and continues to be written from an American rather than an international perspective. This introduction seeks to highlight the growth of research into expatriation to set the context for the five papers in this special edition that both add to some traditional areas of expatriate research and open up new fields relevant to this area of enquiry in international management and international business

    Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis

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    Funding The study was funded entirely by institutional funds.Peer reviewedPostprin

    2D and 3D Analysis of a Torus-unstable Quiet-Sun Prominence Eruption

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    The role of ideal-MHD instabilities in a prominence eruption is explored through 2D and 3D kinematic analysis of an event observed with the Solar Dynamics Observatory and the Solar Terrestrial Relations Observatory between 22:06 UT on 2013 February 26 and 04:06 UT on 2013 February 27. A series of 3D radial slits are used to extract height–time profiles ranging from the midpoint of the prominence leading edge to the southeastern footpoint. These height–time profiles are fit with a kinematic model combining linear and nonlinear rise phases, returning the nonlinear onset time (t nl) as a free parameter. A range (1.5–4.0) of temporal power indices (i.e., β in the nonlinear term (t−tnl)β{(t-{t}_{\mathrm{nl}})}^{\beta }) are considered to prevent prescribing any particular form of nonlinear kinematics. The decay index experienced by the leading edge is explored using a radial profile of the transverse magnetic field from a PFSS extrapolation above the prominence region. Critical decay indices are extracted for each slit at their own specific values of height at the nonlinear phase onset (h(t nl)) and filtered to focus on instances resulting from kinematic fits with χred2<2{\chi }_{\mathrm{red}}^{2}\lt 2 (restricting β to 1.9–3.9). Based on this measure of the critical decay index along the prominence structure, we find strong evidence that the torus instability is the mechanism driving this prominence eruption. Defining any single decay index as being "critical" is not that critical because there is no single canonical or critical value of decay index through which all eruptions must succeed

    Ultrashort PW laser pulse interaction with target and ion acceleration

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    We present the experimental results on ion acceleration by petawatt femtosecond laser solid interaction and explore strategies to enhance ion energy. The irradiation of micrometer thick (0.2 - 6.0 micron) Al foils with a virtually unexplored intensity regime (8x10^19 W/cm^2 - 1x10^21 W/cm^2) resulting in ion acceleration along the rear and the front surface target normal direction is investigated. The maximum energy of protons and carbon ions, obtained at optimised laser intensity condition (by varying laser energy or focal spot size), exhibit a rapid intensity scaling as I^0.8 along the rear surface target normal direction and I^0.6 along the front surface target normal direction. It was found that proton energy scales much faster with laser energy rather than the laser focal spot size. Additionally, the ratio of maximum ion energy along the both directions is found to be constant for the broad range of target thickness and laser intensities. A proton flux is strongly dominated in the forward direction at relatively low laser intensities. Increasing the laser intensity results in the gradual increase in the backward proton flux and leads to almost equalisation of ion flux in both directions in the entire energy range. These experimental findings may open new perspectives for applications.Comment: 6 pages, 5 figures, 3rd EAAC worksho

    A new emphasis on root traits for perennial grass and legume varieties with environmental and ecological benefits

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    Grasslands cover a significant proportion of the agricultural land within the UK and across the EU, providing a relatively cheap source of feed for ruminants and supporting the production of meat, wool and milk from grazing animals. Delivering efficient animal production from grassland systems has traditionally been the primary focus of grassland‐based research. But there is increasing recognition of the ecological and environmental benefits of these grassland systems and the importance of the interaction between their component plants and a host of other biological organisms in the soil and in adjoining habitats. Many of the ecological and environmental benefits provided by grasslands emanate from the interactions between the roots of plant species and the soil in which they grow. We review current knowledge on the role of grassland ecosystems in delivering ecological and environmental benefits. We will consider how improved grassland can deliver these benefits, and the potential opportunities for plant breeding to improve specific traits that will enhance these benefits whilst maintaining forage production for livestock consumption. Opportunities for exploiting new plant breeding approaches, including high throughput phenotyping, and for introducing traits from closely related species are discussed

    Deep seam and minesoil carbon sequestration potential of the South Wales Coalfield, UK

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    Combustion of coal for energy generation has been a significant contributor to increased concentrations of atmospheric carbon dioxide. It is of interest to evaluate the potential of former coalfields for mitigating these increases by carbon sequestration and to compare different options to achieving this end. Here, carbon sequestration in residual coal seams and through reclamation of spoil tips is compared, and their carbon dioxide storage potential in the South Wales Coalfield estimated. Coal seam sequestration estimates come from an established methodology and consider the total unmined coal resource below 500 m deep with potential for carbon sequestration. The most likely effective deep seam storage capacity is 104.9 Mt carbon dioxide, taking account of reservoir conditions and engineering factors. Whilst many spoil tips in South Wales have been reclaimed, the focus has not been on carbon sequestration potential. Estimates of minesoil restoration sequestration capacity were based on a survey of restored minesoil and vegetation carbon stocks, mainly on sites 20–30 years after restoration; data from this survey were then extrapolated to the coalfield as a whole. Minesoil storage is estimated at 1.5 or 2.5 Mt (+2.2 Mt in tree biomass) carbon dioxide based on average grassland or woodland measurements, respectively; modelled data predicted equilibrium values of 2.9 and 2.6 Mt carbon dioxide respectively in grassland or woodland minesoils. If all sites achieved close to the maximum capacity in their land use class, minesoil storage capacity would increase to 2.1 or 3.9 Mt carbon dioxide, respectively. Combining the best woodland minesoil and standing biomass values, sequestration capacity increases to 7.2 Mt carbon dioxide. The wider social, economic, environmental and regulatory constraints to achieving this sequestration for each approach are discussed. Coal seam sequestration has a much higher capacity but sequestration in mine sites is less costly and has fewer regulatory constraints. Findings indicate a significant combined potential for carbon sequestration in the South Wales Coalfield and highlight challenges in achieving this potential. On a global scale, ex-coalfield sequestration could contribute to broader efforts to mitigate emissions

    SULIS: a coronal magnetism explorer for ESA’s Voyage 2050

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    Magnetism dominates the structure and dynamics of the solar corona. To understand the true nature of the solar corona and the long-standing coronal heating problem requires measuring the vector magnetic field of the corona at a sufficiently high resolution (spatially and temporally) across a large Field-of-View (FOV). Despite the importance of the magnetic field in the physics of the corona and despite the tremendous progress made recently in the remote sensing of solar magnetic fields, reliable measurements of the coronal magnetic field strength and orientation do not exist. This is largely due to the weakness of coronal magnetic fields, previously estimated to be on the order of 1-10 G, and the difficulty associated with observing the extremely faint solar corona emission. With the Solar cUbesats for Linked Imaging Spectro-polarimetry (SULIS) mission, we plan to finally observe, in detail and over the long-term, uninterrupted measurements of the coronal magnetic vector field using a new and very affordable instrument design concept. This will be profoundly important in the study of local atmospheric coronal heating processes, as well as in measuring the nature of magnetic clouds, in particular, within geoeffective Earth-bound Coronal Mass Ejections (CMEs) for more accurate forecasting of severe space weather activity

    SULIS: a coronal magnetism explorer for ESA’s Voyage 2050

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    Magnetism dominates the structure and dynamics of the solar corona. To understand the true nature of the solar corona and the long-standing coronal heating problem requires measuring the vector magnetic field of the corona at a sufficiently high resolution (spatially and temporally) across a large Field-of-View (FOV). Despite the importance of the magnetic field in the physics of the corona and despite the tremendous progress made recently in the remote sensing of solar magnetic fields, reliable measurements of the coronal magnetic field strength and orientation do not exist. This is largely due to the weakness of coronal magnetic fields, previously estimated to be on the order of 1-10 G, and the difficulty associated with observing the extremely faint solar corona emission. With the Solar cUbesats for Linked Imaging Spectro-polarimetry (SULIS) mission, we plan to finally observe, in detail and over the long-term, uninterrupted measurements of the coronal magnetic vector field using a new and very affordable instrument design concept. This will be profoundly important in the study of local atmospheric coronal heating processes, as well as in measuring the nature of magnetic clouds, in particular, within geoeffective Earth-bound Coronal Mass Ejections (CMEs) for more accurate forecasting of severe space weather activity

    A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

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    This work is supported by Cancer Research UK Grant C434/A13067 (M.H.T & R.T.H) and Wellcome Trust Grant 098391/Z/12/7 (R.T.H.).Aspirin, or acetylsalicylic acid is widely used to control pain, inflammation and fever. Important to this function is its ability to irreversibly acetylate cyclooxygenases at active site serines. Aspirin has the potential to acetylate other amino-acid side-chains, leading to the possibility that aspirin-mediated lysine acetylation could explain some of its as-yet unexplained drug actions or side-effects. Using isotopically labeled aspirin-d3, in combination with acetylated lysine purification and LC-MS/MS, we identified over 12000 sites of lysine acetylation from cultured human cells. Although aspirin amplifies endogenous acetylation signals at the majority of detectable endogenous sites, cells tolerate aspirin mediated acetylation very well unless cellular deacetylases are inhibited. Although most endogenous acetylations are amplified by orders of magnitude, lysine acetylation site occupancies remain very low even after high doses of aspirin. This work shows that while aspirin has enormous potential to alter protein function, in the majority of cases aspirin-mediated acetylations do not accumulate to levels likely to elicit biological effects. These findings are consistent with an emerging model for cellular acetylation whereby stoichiometry correlates with biological relevance, and deacetylases act to minimize the biological consequences non-specific chemical acetylations.Publisher PDFPeer reviewe

    Magnetism in Semiconducting Molybdenum Dichalcogenides

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    Transition metal dichalcogenides (TMDs) are interesting for understanding fundamental physics of two-dimensional materials (2D) as well as for many emerging technologies, including spin electronics. Here, we report the discovery of long-range magnetic order below TM = 40 K and 100 K in bulk semiconducting TMDs 2H-MoTe2 and 2H-MoSe2, respectively, by means of muon spin-rotation (muSR), scanning tunneling microscopy (STM), as well as density functional theory (DFT) calculations. The muon spin rotation measurements show the presence of a large and homogeneous internal magnetic fields at low temperatures in both compounds indicative of long-range magnetic order. DFT calculations show that this magnetism is promoted by the presence of defects in the crystal. The STM measurements show that the vast majority of defects in these materials are metal vacancies and chalcogen-metal antisites which are randomly distributed in the lattice at the sub-percent level. DFT indicates that the antisite defects are magnetic with a magnetic moment in the range of 0.9-2.8 mu_B. Further, we find that the magnetic order stabilized in 2H-MoTe2 and 2H-MoSe2 is highly sensitive to hydrostatic pressure. These observations establish 2H-MoTe2 and 2H-MoSe2 as a new class of magnetic semiconductors and opens a path to studying the interplay of 2D physics and magnetism in these interesting semiconductors.Comment: 13 pages, 10 Figure
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