545 research outputs found
Encouraging Undergraduate-Faculty Collaborative Research
This paper is the result of the authorsâ participation in a panel session at the Southwest Regional Meeting of the American Accounting Association in Houston, Texas in March 2008. Robert J. Walsh presented an earlier version of this manuscript at the Northeast Regional Meeting of the American Accounting Association in Newport, Rhode Island in November 2008. The authors wish to recognize the contributions of the program chairs, anonymous reviewers, and panel session participants for their helpful comments and suggestions
Charge Exchange Spectra of Hydrogenic and He-like Iron
We present H-like Fe XXVI and He-like Fe XXV charge-exchange spectra
resulting from collisions of highly charged iron with N2 gas at an energy of 10
eV/amu in an electron beam ion trap. Although individual high-n emission lines
are not resolved in our measurements, we observe that the most likely level for
Fe25+ --> Fe24+ electron capture is n~9, in line with expectations, while the
most likely value for Fe26+ --> Fe25+ charge exchange is significantly higher.
In the Fe XXV spectrum, the K-alpha emission feature dominates, whether
produced via charge exchange or collisional excitation. The K-alpha centroid is
lower in energy for the former case than the latter (6666 versus 6685 eV,
respectively), as expected because of the strong enhancement of emission from
the forbidden and intercombination lines, relative to the resonance line, in
charge-exchange spectra. In contrast, the Fe XXVI high-n Lyman lines have a
summed intensity greater than that of Ly-alpha, and are substantially stronger
than predicted from theoretical calculations of charge exchange with atomic H.
We conclude that the angular momentum distribution resulting from electron
capture using a multi-electron target gas is significantly different from that
obtained with H, resulting in the observed high-n enhancement. A discussion is
presented of the relevance of our results to studies of diffuse Fe emission in
the Galactic Center and Galactic Ridge, particularly with ASTRO-E2/Suzaku.Comment: 16 pages, 4 figures (3 color), accepted by Ap
Universal 1/f Noise from Dissipative SOC Models
We introduce a model able to reproduce the main features of 1/f noise:
hyper-universality (the power-law exponents are independent on the dimension of
the system; we show here results in d=1,2) and apparent lack of a low-frequency
cutoff in the power spectrum. Essential ingredients of this model are an
activation-deactivation process and dissipation.Comment: 3 Latex pages, 2 eps Figure
Defects in SiO2 as the possible origin of near interface traps in the SiCâSiO2 system: A systematic theoretical study
A systematic study of the level positions of intrinsic and carbon defects in SiO2 is presented, based on density functional calculations with a hybrid functional in an alpha-quartz supercell. The results are analyzed from the point of view of the near interface traps (NIT), observed in both SiC/SiO2 and Si/SiO2 systems, and assumed to have their origins in the oxide. It is shown that the vacancies and the oxygen interstitial can be excluded as the origin of such NIT, while the silicon interstitial and carbon dimers give rise to gap levels in the energy range inferred from experiments. The properties of these defects are discussed in light of the knowledge about the SiC/SiO2 interface
Noise Probe of the Dynamic Phase Separation in La2/3Ca1/3MnO3
Giant Random Telegraph Noise (RTN) in the resistance fluctuation of a
macroscopic film of perovskite-type manganese oxide La2/3Ca1/3MnO3 has been
observed at various temperatures ranging from 4K to 170K, well below the Curie
temperature (TC = 210K). The amplitudes of the two-level-fluctuations (TLF)
vary from 0.01% to 0.2%. We use a statistical analysis of the life-times of the
TLF to gain insight into the microscopic electronic and magnetic state of this
manganite. At low temperature (below 30K) The TLF is well described by a
thermally activated two-level model. An estimate of the energy difference
between the two states is inferred. At higher temperature (between 60K and
170K) we observed critical effects of the temperature on the life-times of the
TLF. We discuss this peculiar temperature dependence in terms of a sharp change
in the free energy functional of the fluctuators. We attribute the origin of
the RTN to be a dynamic mixed-phase percolative conduction process, where
manganese clusters switch back and forth between two phases that differ in
their conductivity and magnetization.Comment: 15 pages, PDF only, Phys. Rev. Lett. (in press
Relativistic K shell decay rates and fluorescence yields for Zn, Cd and Hg
In this work we use the multiconfiguration Dirac-Fock method to calculate the
transition probabilities for all possible decay channels, radiative and
radiationless, of a K shell vacancy in Zn, Cd and Hg atoms. The obtained
transition probabilities are then used to calculate the corresponding
fluorescence yields which are compared to existing theoretical, semi-empirical
and experimental results
ABIN1 dysfunction as a genetic basis for lupus nephritis
The genetic factors underlying the pathogenesis of lupus nephritis associated with systemic lupus erythematosus are largely unknown, although animal studies indicate that nuclear factor (NF)-?B is involved. We reported previously that aknockin mouse expressinganin active form of ABIN1 (ABIN1[D485N]) develops lupus-like autoimmune disease and demonstrates enhanced activation of NF-?B and mitogen-activated protein kinases in immune cells after toll-like receptor stimulation. In the current study, we show that ABIN1[D485N] mice develop progressive GN similar to class III and IV lupus nephritis in humans. To investigate the clinical relevance of ABIN1 dysfunction, we genotyped five single-nucleotide polymorphisms in the gene encoding ABIN1, TNIP1, in samples from European-American, African American, Asian, Gullah, and Hispanic participants in the Large Lupus Association Study 2. Comparing cases of systemic lupus erythematosus with nephritis and cases ofsystemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans. Comparing cases of systemic lupus erythematosus with nephritis and healthy controls revealed a stronger association at rs7708392 in European Americans but not at rs4958881 in African Americans. Our data suggest that variants in the TNIP1 gene are associated with the risk for lupus nephritis and could be mechanistically involved in disease development via aberrant regulation of NF-?B and mitogen-activated protein kinase activity. Copyright © 2013 by the American Society of Nephrology
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease characterized by loss of immune tolerance to nuclear and cell surface antigens. Previous genome-wide association studies (GWAS) had modest sample sizes, reducing their scope and reliability. Our study comprised 7,219 cases and 15,991 controls of European ancestry, constituting a new GWAS, a meta-analysis with a published GWAS and a replication study. We have mapped 43 susceptibility loci, including ten new associations. Assisted by dense genome coverage, imputation provided evidence for missense variants underpinning associations in eight genes. Other likely causal genes were established by examining associated alleles for cis-acting eQTL effects in a range of ex vivo immune cells. We found an over-representation (n = 16) of transcription factors among SLE susceptibility genes. This finding supports the view that aberrantly regulated gene expression networks in multiple cell types in both the innate and adaptive immune response contribute to the risk of developing SLE
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