371 research outputs found

    Influence of Hydrogen and Low Temperature on Pipeline Steels Mechanical Behaviour

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    Abstract In the presence of H2S, metallic materials, such as carbon and low alloy steels, may suffer hydrogen damage and hydrogen embrittlement. Gas transporting pipes in low temperature environment, during the shutdown and the subsequent re-starting operations, are exposed to very low temperatures (T=-40 °C). In the presence of high H2S content in the gas, the risk of brittle failure can be increased due to the effect of hydrogen on steel toughness. In this paper the influence of hydrogen and low temperature on mechanical properties of two pipeline materials, F22 low alloy and X65 micro-alloyed steels, is studied. Steels have been hydrogen charged by means of an electrochemical method: diffusible hydrogen content of steels is in the range 0.6 to 2 ppm. Charpy and J-R curves tests were carried out in the range from room temperature to T=-120 °C. Hydrogen affects mechanical properties of the tested materials, mainly reducing fracture toughness in J integral tests, while little influence has been observed in CV tests. Fracture surface examination confirms the results of mechanical testing

    A new case of t(5;14)(q31;q32) in a pediatric acute lymphoblastic leukemia presenting with hypereosinophilia

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    Case report of a translocation : A new case of t(5;14)(q31;q32) in a pediatric acute lymphoblastic leukemia presenting with hypereosinophilia

    Expanding the phenotypic and genetic spectrum of radioulnar synostosis associated hematological disease.

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    Medical Research Council, Children with Cancer and Bloodwise

    Enfermedad de Gaucher en Argentina: un informe del Registro Internacional de Gaucher y del Grupo Argentino de DiagnĂłstico y Tratamiento de la Enfermedad de Gaucher

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    La Enfermedad de Gaucher por su baja frecuencia estĂĄ incluida dentro de las enfermedades huĂ©rfanas. En 1991 comenzĂł el ingreso de pacientes en el Registro Internacional de Gaucher. En 1992 se incorporaron los primeros dos pacientes de LatinoamĂ©rica. En 2006 se creĂł el Grupo Argentino de DiagnĂłstico y Tratamiento de la Enfermedad de Gaucher siendo sus objetivos principales el entendimiento de la prevalencia, presentaciĂłn, manejo y tratamiento de la Enfermedad de Gaucher en Argentina. Hasta el 1 de febrero del 2013 ingresaron al Registro Internacional 5.986 pacientes provenientes de 60 paĂ­ses, de los cuales 133 (2.22%) fueron argentinos. El anĂĄlisis de esta publicaciĂłn fue realizado sobre 133 pacientes con Enfermedad de Gaucher. Esta es la primera publicaciĂłn del Grupo Argentino de DiagnĂłstico y Tratamiento en base a los datos del Registro Internacional. La casuĂ­stica argentina mostrĂł un predominio femenino y la forma clĂ­nica mĂĄs frecuente fue el tipo 1 (97.7%, n=128). El genotipo fue identificado en 57 pacientes (42.9%), siendo el mĂĄs frecuente el N370S/ otro alelo (82.5%). Entre los pacientes con datos reportados, los sĂ­ntomas basales predominantes, previos al inicio del tratamiento con Imiglucerasa que predominaron fueron la esplenomegalia (100%, n=13) y la hepatomegalia (88.9%, n=8) y como citopenias mĂĄs frecuentes, la trombocitopenia (64.2%, n=34) y la anemia (45.9%, n=28). La infiltraciĂłn de la mĂ©dula Ăłsea como un marcador especĂ­fico de enfermedad Ăłsea se encontrĂł en el 50% de los pacientes. En total, el 85.7% de los pacientes argentinos reciben terapia de reemplazo enzimĂĄtico con Imiglucerasa, logrĂĄndose las metas terapĂ©uticas, en la mayorĂ­a de los casos, en la Ășltima evaluaciĂłn. Las metas terapĂ©uticas mĂĄs frecuentemente alcanzadas resultaron: el control de las manifestaciones Ăłseas (dolor Ăłseo y crisis Ăłsea, 81.9% y 99% respectivamente) y la normalizaciĂłn de la hemoglobina (86.5%). La terapia de reemplazo enzimĂĄtica con Imiglucerasa, a largo plazo en la poblaciĂłn argentina demostrĂł ser una herramienta eficaz para mejorar los parĂĄmetros clĂ­nicos y bioquĂ­micos de la Enfermedad de Gaucher tipo1.Fil: Drelichman, G.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo GutiĂ©rrez"; ArgentinaFil: FernĂĄndez Escobar, NicolĂĄs. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo GutiĂ©rrez"; ArgentinaFil: Basack, Nora. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo GutiĂ©rrez"; ArgentinaFil: Kohan, R.. Registro Argentino de Gaucher; ArgentinaFil: Watman, N.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos MejĂ­a"; ArgentinaFil: Bolesina, M.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos MejĂ­a"; ArgentinaFil: Elena, G.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Veber, S. E.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Dragosky, M.. Gobierno de la Ciudad de Buenos Aires. Hospital de OncologĂ­a Marie Curie; ArgentinaFil: Annetta, I.. Gobierno de la Ciudad de Buenos Aires. Hospital de OncologĂ­a Marie Curie; ArgentinaFil: Feliu, A.. Gobierno de la Ciudad de Buenos Aires. Hospital de PediatrĂ­a "Juan P. Garrahan"; ArgentinaFil: Sciuccati, Gabriela. Gobierno de la Ciudad de Buenos Aires. Hospital de PediatrĂ­a "Juan P. Garrahan"; ArgentinaFil: Cuello, MarĂ­a Fernanda. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Fynn, Alcira. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Dodelson de Kremer, Raquel. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Angaroni, Celia Juana. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Giner Ayala, Alicia. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Del Valle Oller, Ana MarĂ­a. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Guelbert, Norberto Bernardo. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Delgado, MarĂ­a Andrea. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Becerra, Adriana BerĂłnica. Provincia de Buenos Aires. Ministerio de Salud. Hospital de Niños "Sor MarĂ­a Ludovica" de la Plata; ArgentinaFil: Oliveri, MarĂ­a Beatriz. Universidad de Buenos Aires. Facultad de Medicina. Hospital de ClĂ­nicas General San MartĂ­n; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: LarroudĂ©, M.. Centro MĂ©dico TIEMPO; ArgentinaFil: Masllorens, F.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Nacional “Prof. Dr. A. Posadas"; ArgentinaFil: Szlago, M.. FundaciĂłn para el eEstudio de las Enfermedades NeurometabĂłlicas; Argentina. Laboratorio de NeuroquĂ­mica “Dr. N. A. Chamoles”; ArgentinaFil: Schenone, A.. Laboratorio de NeuroquĂ­mica “Dr. N. A. Chamoles”; Argentina. FundaciĂłn para el eEstudio de las Enfermedades NeurometabĂłlicas; Argentin

    Measurement of τL using the Bs0 →J/ψη decay mode

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    Using a proton–proton collision data sample collected by the LHCb detector and corresponding to an integrated luminosity of 5.7fb-1 , the lifetime of the light Bs0 mass eigenstate, τL , is measured using the Bs0→J/ψη decay mode to be τL=1.445±0.016(stat)±0.008(syst)ps. A combination of this result with a previous LHCb analysis using an independent dataset corresponding to 3 fb - 1 of integrated luminosity gives τL=1.452±0.014±0.007±0.002ps, where the first uncertainty is statistical, the second due to the uncorrelated part of the systematic uncertainty and the third due to the correlated part of the systematic uncertainty

    A study of CP violation in the decays B±→[K+K-π+π-]Dh± (h= K, π) and B±→[π+π-π+π-]Dh±

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    The first study of CP violation in the decay mode B±→[K+K-π+π-]Dh± , with h= K, π , is presented, exploiting a data sample of proton–proton collisions collected by the LHCb experiment that corresponds to an integrated luminosity of 9 \,fb - 1 . The analysis is performed in bins of phase space, which are optimised for sensitivity to local CP asymmetries. CP -violating observables that are sensitive to the angle Îł of the Unitarity Triangle are determined. The analysis requires external information on charm-decay parameters, which are currently taken from an amplitude analysis of LHCb data, but can be updated in the future when direct measurements become available. Measurements are also performed of phase-space integrated observables for B±→[K+K-π+π-]Dh± and B±→[π+π-π+π-]Dh± decays

    Measurement of antiproton production from antihyperon decays in pHe collisions at √sNN=110GeV

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    The interpretation of cosmic antiproton flux measurements from space-borne experiments is currently limited by the knowledge of the antiproton production cross-section in collisions between primary cosmic rays and the interstellar medium. Using collisions of protons with an energy of 6.5 TeV incident on helium nuclei at rest in the proximity of the interaction region of the LHCb experiment, the ratio of antiprotons originating from antihyperon decays to prompt production is measured for antiproton momenta between 12 and 110GeV\!/c . The dominant antihyperon contribution, namely Λ¯ → pÂŻ π+ decays from promptly produced Λ¯ particles, is also exclusively measured. The results complement the measurement of prompt antiproton production obtained from the same data sample. At the energy scale of this measurement, the antihyperon contributions to antiproton production are observed to be significantly larger than predictions of commonly used hadronic production models

    Search for CP\textit{CP} violation in the phase space of D0→KS0K±π∓D^{0} \rightarrow K_{S}^{0} K^{\pm} \pi^{\mp} decays with the energy test

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    A search for CP\textit{CP} violation in D0→KS0K+π−D^{0} \rightarrow K_{S}^{0} K^{+} \pi^{-} and D0→KS0K−π+D^{0} \rightarrow K_{S}^{0} K^{-} \pi^{+} decays is reported. The search is performed using an unbinned model-independent method known as the energy test that probes local CP\textit{CP} violation in the phase space of the decays. The data analysed correspond to an integrated luminosity of 5.4 5.4~fb−1^{-1} collected in proton-proton collisions by the LHCb experiment at a centre-of-mass energy of s=13\sqrt{s}=13~TeV, amounting to approximately 950000 and 620000 signal candidates for the D0→KS0K−π+D^{0} \rightarrow K_{S}^{0} K^{-} \pi^{+} and D0→KS0K+π−D^{0} \rightarrow K_{S}^{0} K^{+} \pi^{-} modes, respectively. The method is validated using D0→K−π+π−π+D^{0} \rightarrow K^{-} \pi^{+} \pi^{-} \pi^{+} and D0→KS0π+π−D^{0} \rightarrow K_{S}^{0} \pi^{+} \pi^{-} decays, where CP\textit{CP}-violating effects are expected to be negligible, and using background-enhanced regions of the signal decays. The results are consistent with CP\textit{CP} symmetry in both the D0→KS0K−π+D^{0} \rightarrow K_{S}^{0} K^{-} \pi^{+} and the D0→KS0K+π−D^{0} \rightarrow K_{S}^{0} K^{+} \pi^{-} decays, with pp-values for the hypothesis of no CP\textit{CP} violation of 70% and 66%, respectively.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-019.html (LHCb public pages

    Studies of η\eta and ηâ€Č\eta' production in pppp and ppPb collisions

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    The production of η\eta and ηâ€Č\eta' mesons is studied in proton-proton and proton-lead collisions collected with the LHCb detector. Proton-proton collisions are studied at center-of-mass energies of 5.025.02 and 13 TeV13~{\rm TeV}, and proton-lead collisions are studied at a center-of-mass energy per nucleon of 8.16 TeV8.16~{\rm TeV}. The studies are performed in center-of-mass rapidity regions 2.5<yc.m.<3.52.5<y_{\rm c.m.}<3.5 (forward rapidity) and −4.0<yc.m.<−3.0-4.0<y_{\rm c.m.}<-3.0 (backward rapidity) defined relative to the proton beam direction. The η\eta and ηâ€Č\eta' production cross sections are measured differentially as a function of transverse momentum for 1.5<pT<10 GeV1.5<p_{\rm T}<10~{\rm GeV} and 3<pT<10 GeV3<p_{\rm T}<10~{\rm GeV}, respectively. The differential cross sections are used to calculate nuclear modification factors. The nuclear modification factors for η\eta and ηâ€Č\eta' mesons agree at both forward and backward rapidity, showing no significant evidence of mass dependence. The differential cross sections of η\eta mesons are also used to calculate η/π0\eta/\pi^0 cross section ratios, which show evidence of a deviation from the world average. These studies offer new constraints on mass-dependent nuclear effects in heavy-ion collisions, as well as η\eta and ηâ€Č\eta' meson fragmentation.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/Publications/p/LHCb-PAPER-2023-030.html (LHCb public pages
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